rv3466
rv3466
hypothetical protein
M. tuberculosis · H37Rv
[MycoBrowser] [AlphaFold] [UniProt] [Orthologs] [U19] [TnSeq DB] [SeqHub] [evo-mtb]
H37Rv Coordinates: 3883704 – 3884372
Vulnerability Index (VI):
M. smegmatis homologs MSMEG6573, MSMEG2663
M. abscessus homologs MAB0394c, MAB0990c, MAB2374c
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (4) Cortes, 2013 (5) Shell, 2015 (3) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 (5) PMID: 24268774 infA Rv3463 rmlB rmlC Rv3466 Rv3467 Rv3468c mhpE ilvB2
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>rv3466_Rv3466_dna
GTACTTGTGCTCGGCGGAATACAATCCGCAGCGCGAGCACACCATCTGCGCCACAGATCCGACGTTGGCGGTCGATTGGCCGCTGGTCGATGGCGCTGCCCCCAGCCTGTCCGACCGTGATGCCGCTGCGCCCAGCTTCGAGGATGTGCGCGCGTCTGGCCTGCTGCCCAGGTGGGAACAGACGCAGCGGTTCATTGGGGAGATGCGCGGCACCTAGCTCGGTAATCCCTTGTGTTGCTTTAGCTTCAGCGGTCACAGCGCGGCGATTGTTGTCGGTGGCCCCTCGTAGAATTTGGGGTATGGGTTCGGGTAGCCGCGAACGGATTGTCGAGGTCTTTGATGCGCTGGATGCCGAGCTGGACCGCTTGGACGAGGTGTCTTTTGAGGTGTTGACCACCCCAGAACGGCTGCGGTCTCTGGAACGTCTGGAATGCTTGGTGCGCCGGCTACCGGCGGTGGGTCACGCGTTGATCAACCAACTTGACGCCCAAGCCAGCGAGGAAGAACTGGGCGGCACGCTGTGCTGCGCGCTGGCCAACCGGTTACGCATCACCAAGCCCGACGCCGCCCGGCGCATCGCCGACGCCGCCGATCTCGGACCTCGTCGAGCACTCACCGGTGAACCGCTAGCCCCACAGTTGACCGCCACCGCCACCGCCCAACGCCAGGGCCTGATCGGCGAGGCGCACGTCAAAGTGATTCGCGCCCTTTTTCGCCCACCTGCCCGCCGCGGTGGATGTGTCCACCCGCCAGGCCGCCGAAGCCGACCTGGCCGGCAAAGCCGCTCAATATCGTCCCGACGAGCTGGCCCGCTACGCCCAGCGGGTCATGGACTGGCTACACCCCGACGGCGACCTCACCGACACCGAACGCGCCCGCAAACGCGGCATCACCCTGAGCAACCAGCAATACGACGGCATGTCACGGCTAAGTGGCTACCTGACCCCCCAAGCGCGGGCCACCTTTGA

Protein Sequence 

>Rv3466_Rv3466_protein
MGSGSRERIVEVFDALDAELDRLDEVSFEVLTTPERLRSLERLECLVRRLPAVGHALINQLDAQASEEELGGTLCCALANRLRITKPDAARRIADAADLGPRRALTGEPLAPQLTATATAQRQGLIGEAHVKVIRALFRPPARRGGCVHPPGRRSRPGRQSRSISSRRAGPLRPAGHGLATPRRRPHRHRTRPQTRHHPEQPAIRRHVTAKWLPDPPSAGHL

Essentiality:

Call Condition Type Source Notes
Non Essential in vitro TnSeq [DeJesus et al. (2017)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]

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