1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Q	Q	T	A	W	A	P	R	T	S	G	I	A	G	C	G	A	G	G	V	V	M	A	I	A	S	V	T	L	V	T	D	T	P	G	R	V	L	T	G	V	A	A	L	G	L	I	L	F	A	S	A	T	W	R	A	R	P	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?																				?	?	?																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	A	I	T	P	D	G	L	A	I	R	G	W	F	R	T	Q	L	L	R	H	S	N	I	K	I	I	R	I	D	E	F	R	R	Y	G	R	L	V	R	L	L	E	I	E	T	V	S	G	G	L	L	I	L	S	R	W	D	L	G
Secondary structure
SS confidence
Disorder																														?	?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.
Sequence		T	D	P	V	E	V	L	D	A	L	T	A	A	G	Y	A	G	R	G	Q	R
Secondary structure
SS confidence
Disorder														?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 19%) Alpha helix ( 44%) Beta strand ( 23%) TM helix ( 11%) (View membrane topology prediction)

Rank Aligned region

PDB 1mpg chain A domain 2 Region: 117 - 134 Aligned: 18 Modelled: 18 Confidence: 60.5% Identity: 39% Fold: TBP-like Superfamily: TATA-box binding protein-like Family: DNA repair glycosylase, N-terminal domain Phyre2 PDB 1gg3 chain A domain 2 Region: 61 - 87 Aligned: 27 Modelled: 27 Confidence: 44.1% Identity: 19% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Third domain of FERM Phyre2 PDB 3tu3 chain A Region: 32 - 67 Aligned: 36 Modelled: 36 Confidence: 37.6% Identity: 22% PDB header:toxin/toxin chaperone Chain: A: PDB Molecule:exou chaperone; PDBTitle: 1.92 angstrom resolution crystal structure of the full-length spcu in2 complex with full-length exou from the type iii secretion system of3 pseudomonas aeruginosa Phyre2 PDB 1e5w chain A domain 2 Region: 61 - 87 Aligned: 27 Modelled: 27 Confidence: 37.2% Identity: 30% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Third domain of FERM Phyre2 PDB 4akx chain A Region: 32 - 67 Aligned: 36 Modelled: 36 Confidence: 34.6% Identity: 22% PDB header:transport protein Chain: A: PDB Molecule:spcu; PDBTitle: structure of the heterodimeric complex exou-spcu from the type iii2 secretion system (t3ss) of pseudomonas aeruginosa Phyre2 PDB 1isn chain A domain 2 Region: 61 - 87 Aligned: 27 Modelled: 27 Confidence: 31.9% Identity: 26% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Third domain of FERM Phyre2 PDB 1j19 chain A domain 2 Region: 61 - 87 Aligned: 27 Modelled: 27 Confidence: 27.8% Identity: 26% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Third domain of FERM Phyre2 PDB 1ef1 chain A domain 2 Region: 61 - 87 Aligned: 27 Modelled: 27 Confidence: 24.9% Identity: 26% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Third domain of FERM Phyre2 PDB 1ef4 chain A Region: 120 - 135 Aligned: 16 Modelled: 16 Confidence: 24.5% Identity: 50% Fold: DNA/RNA-binding 3-helical bundle Superfamily: RNA polymerase subunit RPB10 Family: RNA polymerase subunit RPB10 Phyre2 PDB 2mc5 chain A Region: 114 - 129 Aligned: 16 Modelled: 16 Confidence: 21.6% Identity: 38% PDB header:protein binding Chain: A: PDB Molecule:45l; PDBTitle: a bacteriophage transcription regulator inhibits bacterial2 transcription initiation by -factor displacement Phyre2 PDB 1ywy chain A domain 1 Region: 74 - 136 Aligned: 47 Modelled: 54 Confidence: 18.6% Identity: 26% Fold: PH domain-like barrel Superfamily: PA2021-like Family: PA2021-like Phyre2 PDB 4qiw chain V Region: 120 - 135 Aligned: 16 Modelled: 16 Confidence: 18.3% Identity: 50% PDB header:transcription Chain: V: PDB Molecule:dna-directed rna polymerase subunit n; PDBTitle: crystal structure of euryarchaeal rna polymerase from thermococcus2 kodakarensis Phyre2 PDB 2zpy chain A domain 2 Region: 61 - 114 Aligned: 48 Modelled: 54 Confidence: 17.0% Identity: 15% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Third domain of FERM Phyre2 PDB 1e5w chain A Region: 61 - 87 Aligned: 27 Modelled: 27 Confidence: 16.7% Identity: 26% PDB header:membrane protein Chain: A: PDB Molecule:moesin; PDBTitle: structure of isolated ferm domain and first long helix of moesin Phyre2 PDB 2pmz chain N Region: 120 - 135 Aligned: 16 Modelled: 16 Confidence: 13.0% Identity: 44% PDB header:translation, transferase Chain: N: PDB Molecule:dna-directed rna polymerase subunit n; PDBTitle: archaeal rna polymerase from sulfolobus solfataricus Phyre2 PDB 4g6t chain A Region: 101 - 141 Aligned: 39 Modelled: 41 Confidence: 12.7% Identity: 15% PDB header:chaperone Chain: A: PDB Molecule:type iii chaperone protein shca; PDBTitle: structure of the hopa1-scha chaperone-effector complex Phyre2 PDB 1qup chain A domain 2 Region: 99 - 135 Aligned: 33 Modelled: 37 Confidence: 10.7% Identity: 15% Fold: Ferredoxin-like Superfamily: HMA, heavy metal-associated domain Family: HMA, heavy metal-associated domain Phyre2 PDB 6d2k chain A Region: 61 - 93 Aligned: 33 Modelled: 33 Confidence: 9.8% Identity: 18% PDB header:signaling protein Chain: A: PDB Molecule:ferm, arhgef and pleckstrin domain-containing protein 2; PDBTitle: crystal structure of the ferm domain of mouse farp2 Phyre2 PDB 2i1k chain A Region: 61 - 87 Aligned: 27 Modelled: 27 Confidence: 9.6% Identity: 22% PDB header:cell adhesion, membrane protein Chain: A: PDB Molecule:moesin; PDBTitle: moesin from spodoptera frugiperda reveals the coiled-coil domain at2 3.0 angstrom resolution Phyre2 PDB 4rm9 chain A Region: 61 - 87 Aligned: 27 Modelled: 27 Confidence: 9.0% Identity: 22% PDB header:peptide binding protein Chain: A: PDB Molecule:ezrin; PDBTitle: crystal structure of human ezrin in space group c2221 Phyre2 1 d1mpga2 2 d1gg3a2 3 c3tu3A_ 4 d1e5wa2 5 c4akxA_ 6 d1isna2 7 d1j19a2 8 d1ef1a2 9 d1ef4a_ 10 c2mc5A_ 11 d1ywya1 12 c4qiwV_ 13 d2zpya2 14 c1e5wA_ 15 c2pmzN_ 16 c4g6tA_ 17 d1qupa2 18 c6d2kA_ 19 c2i1kA_ 20 c4rm9A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42