1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	D	R	I	H	V	Q	P	A	H	L	R	Q	A	A	A	H	H	Q	Q	T	A	D	Y	L	R	T	V	P	S	S	H	D	A	I	R	E	S	L	D	S	L	G	P	I	F	S	E	L	R	D	T	G	R	E	L	L	E	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.
Sequence		R	K	Q	C	Y	Q	Q	Q	A	D	N	H	A	D	I	A	Q	N	L	R	T	S	A	A	M	W	E	Q	H	E	R	A	A	S	R	S	L	G	N	I	I	D	G	S	R
Secondary structure
SS confidence
Disorder								?	?	?	?	?																								?	?					?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 18%) Alpha helix ( 86%) Beta strand ( 0%)

Rank Aligned region

PDB 4iog chain D Region: 1 - 88 Aligned: 85 Modelled: 88 Confidence: 89.4% Identity: 20% PDB header:unknown function Chain: D: PDB Molecule:secreted protein esxb; PDBTitle: the crystal structure of a secreted protein esxb (wild-type, in p212 space group) from bacillus anthracis str. sterne Phyre2 PDB 2vs0 chain B Region: 5 - 88 Aligned: 82 Modelled: 84 Confidence: 87.3% Identity: 16% PDB header:cell invasion Chain: B: PDB Molecule:virulence factor esxa; PDBTitle: structural analysis of homodimeric staphylococcal aureus2 virulence factor esxa Phyre2 PDB 1wa8 chain A domain 1 Region: 4 - 99 Aligned: 94 Modelled: 96 Confidence: 82.0% Identity: 15% Fold: Ferritin-like Superfamily: EsxAB dimer-like Family: ESAT-6 like Phyre2 PDB 3gvm chain A Region: 4 - 97 Aligned: 92 Modelled: 94 Confidence: 49.4% Identity: 17% PDB header:viral protein Chain: A: PDB Molecule:putative uncharacterized protein sag1039; PDBTitle: structure of the homodimeric wxg-100 family protein from streptococcus2 agalactiae Phyre2 PDB 4lws chain A Region: 4 - 100 Aligned: 86 Modelled: 97 Confidence: 31.7% Identity: 21% PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata Phyre2 PDB 4lws chain B Region: 1 - 83 Aligned: 81 Modelled: 83 Confidence: 24.1% Identity: 10% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata Phyre2 PDB 3zbh chain C Region: 9 - 98 Aligned: 88 Modelled: 90 Confidence: 18.6% Identity: 14% PDB header:unknown function Chain: C: PDB Molecule:esxa; PDBTitle: geobacillus thermodenitrificans esxa crystal form i Phyre2 PDB 3a98 chain A Region: 29 - 86 Aligned: 58 Modelled: 58 Confidence: 16.9% Identity: 22% PDB header:signaling protein Chain: A: PDB Molecule:dedicator of cytokinesis protein 2; PDBTitle: crystal structure of the complex of the interacting regions of dock22 and elmo1 Phyre2 PDB 6fue chain C Region: 56 - 80 Aligned: 24 Modelled: 25 Confidence: 15.6% Identity: 50% PDB header:protein transport Chain: C: PDB Molecule:fapf; PDBTitle: periplasmic coiled coil domain of the fapf amyloid transporter Phyre2 PDB 6fue chain A Region: 56 - 80 Aligned: 24 Modelled: 25 Confidence: 15.6% Identity: 50% PDB header:protein transport Chain: A: PDB Molecule:fapf; PDBTitle: periplasmic coiled coil domain of the fapf amyloid transporter Phyre2 PDB 3bbo chain Z Region: 42 - 85 Aligned: 44 Modelled: 44 Confidence: 13.3% Identity: 23% PDB header:ribosome Chain: Z: PDB Molecule:ribosomal protein l29; PDBTitle: homology model for the spinach chloroplast 50s subunit fitted to 9.4a2 cryo-em map of the 70s chlororibosome Phyre2 PDB 5jzr chain A Region: 76 - 91 Aligned: 16 Modelled: 16 Confidence: 13.1% Identity: 56% PDB header:viral protein Chain: A: PDB Molecule:coat protein; PDBTitle: solid-state mas nmr structure of acinetobacter phage 205 (ap205) coat2 protein in assembled capsid particles Phyre2 PDB 3l8j chain A Region: 25 - 65 Aligned: 41 Modelled: 41 Confidence: 12.9% Identity: 29% PDB header:protein binding Chain: A: PDB Molecule:programmed cell death protein 10; PDBTitle: crystal structure of ccm3, a cerebral cavernous malformation protein2 critical for vascular integrity Phyre2 PDB 1pyv chain A Region: 94 - 104 Aligned: 11 Modelled: 11 Confidence: 11.4% Identity: 73% PDB header:hydrolase Chain: A: PDB Molecule:atp synthase beta chain, mitochondrial precursor; PDBTitle: nmr solution structure of the mitochondrial f1b presequence2 peptide from nicotiana plumbaginifolia Phyre2 PDB 2pl9 chain D Region: 29 - 44 Aligned: 16 Modelled: 16 Confidence: 11.0% Identity: 50% PDB header:signaling protien Chain: D: PDB Molecule:chemotaxis protein chez; PDBTitle: crystal structure of chey-mg(2+)-bef(3)(-) in complex with chez(c19)2 peptide solved from a p2(1)2(1)2 crystal Phyre2 PDB 2e8p chain A Region: 53 - 83 Aligned: 31 Modelled: 31 Confidence: 10.9% Identity: 16% PDB header:signaling protein Chain: A: PDB Molecule:elf3 protein; PDBTitle: solution structure of the n-terminal sam-domain of e74-like2 factor 3 Phyre2 PDB 5mlc chain Z Region: 42 - 85 Aligned: 44 Modelled: 44 Confidence: 10.5% Identity: 20% PDB header:ribosome Chain: Z: PDB Molecule:50s ribosomal protein l29, chloroplastic; PDBTitle: cryo-em structure of the spinach chloroplast ribosome reveals the2 location of plastid-specific ribosomal proteins and extensions Phyre2 PDB 4m70 chain A Region: 75 - 87 Aligned: 13 Modelled: 13 Confidence: 8.7% Identity: 69% PDB header:plant protein Chain: A: PDB Molecule:rx protein; PDBTitle: crystal structure of potato rx-cc domain in complex with rangap2-wpp2 domain Phyre2 PDB 2odm chain A Region: 36 - 53 Aligned: 18 Modelled: 18 Confidence: 8.6% Identity: 44% PDB header:unknown function Chain: A: PDB Molecule:upf0358 protein mw0995; PDBTitle: crystal structure of s. aureus ylan, an essential leucine rich protein2 involved in the control of cell shape Phyre2 PDB 2lnd chain A Region: 14 - 43 Aligned: 29 Modelled: 30 Confidence: 7.9% Identity: 41% PDB header:de novo protein Chain: A: PDB Molecule:de novo designed protein, pfk fold; PDBTitle: solution nmr structure of de novo designed protein, pfk fold,2 northeast structural genomics consortium target or134 Phyre2 1 c4iogD_ 2 c2vs0B_ 3 d1wa8a1 4 c3gvmA_ 5 c4lwsA_ 6 c4lwsB_ 7 c3zbhC_ 8 c3a98A_ 9 c6fueC_ 10 c6fueA_ 11 c3bboZ_ 12 c5jzrA_ 13 c3l8jA_ 14 c1pyvA_ 15 c2pl9D_ 16 c2e8pA_ 17 c5mlcZ_ 18 c4m70A_ 19 c2odmA_ 20 c2lndA_ 21 22 23 24 25 26 27 28 29 30 31 32