1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	V	A	P	H	E	D	P	E	D	H	V	A	P	A	A	Q	R	V	R	A	G	T	L	L	L	A	N	T	D	L	L	E	P	T	F	R	R	S	V	I	Y	I	V	E	H	N	D	G	G	T	L	G	V	V	L	N	R	P	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?	?		?									?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	T	A	V	Y	N	V	L	P	Q	W	A	K	L	A	A	K	P	K	T	M	F	I	G	G	P	V	K	R	D	A	A	L	C	L	A	V	L	R	V	G	A	D	P	E	G	V	P	G	L	R	H	V	A	G	R	L	V	M	V
Secondary structure
SS confidence
Disorder														?	?																										?	?	?		?													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	L	D	A	D	P	E	V	L	A	A	A	V	E	G	V	R	I	Y	A	G	Y	S	G	W	T	I	G	Q	L	E	G	E	I	E	R	D	D	W	I	V	L	S	A	L	P	S	D	V	L	V	G	P	R	A	D	L	W	G	Q
Secondary structure
SS confidence
Disorder					?	?				?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.
Sequence		V	L	R	R	Q	P	L	P	L	S	L	L	A	T	H	P	I	D	L	S	R	N
Secondary structure
SS confidence
Disorder																		?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 20%) Alpha helix ( 23%) Beta strand ( 20%)

Rank Aligned region

PDB 2gs5 chain A domain 1 Region: 13 - 197 Aligned: 185 Modelled: 183 Confidence: 100.0% Identity: 42% Fold: VC0467-like Superfamily: VC0467-like Family: VC0467-like Phyre2 PDB 2mui chain A Region: 12 - 195 Aligned: 179 Modelled: 184 Confidence: 100.0% Identity: 26% PDB header:unknown function Chain: A: PDB Molecule:upf0301 protein algh; PDBTitle: solution structure of the algh protein from pseudomonas aeruginosa,2 pa0405, upf0301 Phyre2 PDB 2gzo chain A domain 1 Region: 20 - 198 Aligned: 175 Modelled: 179 Confidence: 100.0% Identity: 25% Fold: VC0467-like Superfamily: VC0467-like Family: VC0467-like Phyre2 PDB 2aj2 chain A Region: 6 - 190 Aligned: 176 Modelled: 185 Confidence: 100.0% Identity: 29% PDB header:unknown function Chain: A: PDB Molecule:hypothetical upf0301 protein vc0467; PDBTitle: x-ray crystal structure of protein vc0467 from vibrio2 cholerae. northeast structural genomics consortium target3 vcr8. Phyre2 PDB 2ew0 chain A domain 1 Region: 19 - 194 Aligned: 172 Modelled: 176 Confidence: 100.0% Identity: 24% Fold: VC0467-like Superfamily: VC0467-like Family: VC0467-like Phyre2 PDB 2do8 chain A domain 1 Region: 20 - 198 Aligned: 174 Modelled: 179 Confidence: 100.0% Identity: 24% Fold: VC0467-like Superfamily: VC0467-like Family: VC0467-like Phyre2 PDB 2haf chain A domain 1 Region: 20 - 189 Aligned: 166 Modelled: 170 Confidence: 100.0% Identity: 30% Fold: VC0467-like Superfamily: VC0467-like Family: VC0467-like Phyre2 PDB 6j4u chain A Region: 33 - 90 Aligned: 58 Modelled: 58 Confidence: 51.1% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:tubulinyl-tyr carboxypeptidase 1; PDBTitle: structural basis of tubulin detyrosination by vasohibins-svbp enzyme2 complex and functional implications Phyre2 PDB 6qby chain A Region: 33 - 90 Aligned: 58 Modelled: 58 Confidence: 46.4% Identity: 19% PDB header:cytosolic protein Chain: A: PDB Molecule:tubulinyl-tyr carboxypeptidase 2; PDBTitle: crystal structure of vash 2 in complex with svbp Phyre2 PDB 1vpq chain A Region: 137 - 146 Aligned: 10 Modelled: 10 Confidence: 22.5% Identity: 40% Fold: TIM beta/alpha-barrel Superfamily: TM1631-like Family: TM1631-like Phyre2 PDB 2b78 chain A domain 1 Region: 16 - 55 Aligned: 40 Modelled: 40 Confidence: 12.7% Identity: 15% Fold: PUA domain-like Superfamily: PUA domain-like Family: Hypothetical RNA methyltransferase domain (HRMD) Phyre2 PDB 1byy chain A Region: 167 - 186 Aligned: 20 Modelled: 20 Confidence: 12.5% Identity: 5% PDB header:membrane protein Chain: A: PDB Molecule:protein (sodium channel alpha-subunit); PDBTitle: sodium channel iia inactivation gate Phyre2 PDB 1sy6 chain A domain 1 Region: 30 - 44 Aligned: 15 Modelled: 15 Confidence: 8.9% Identity: 13% Fold: Immunoglobulin-like beta-sandwich Superfamily: Immunoglobulin Family: I set domains Phyre2 PDB 4lql chain F Region: 180 - 201 Aligned: 22 Modelled: 22 Confidence: 8.8% Identity: 14% PDB header:isomerase Chain: F: PDB Molecule:l-arabinose isomerase; PDBTitle: crystal structure of l-arabinose isomerase from lactobacillus2 fermentum cgmcc2921 Phyre2 PDB 2zjt chain B Region: 37 - 57 Aligned: 21 Modelled: 21 Confidence: 8.4% Identity: 10% PDB header:isomerase Chain: B: PDB Molecule:dna gyrase subunit b; PDBTitle: crystal structure of dna gyrase b' domain sheds lights on the2 mechanism for t-segment navigation Phyre2 PDB 1jl3 chain A Region: 37 - 47 Aligned: 11 Modelled: 11 Confidence: 8.2% Identity: 9% Fold: Phosphotyrosine protein phosphatases I-like Superfamily: Phosphotyrosine protein phosphatases I Family: Low-molecular-weight phosphotyrosine protein phosphatases Phyre2 PDB 4m7v chain A Region: 35 - 141 Aligned: 94 Modelled: 97 Confidence: 7.9% Identity: 19% PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrofolate reductase; PDBTitle: dihydrofolate reductase from enterococcus faecalis complexed with2 nadp(h)and rab-propyl Phyre2 PDB 6dy3 chain G Region: 170 - 194 Aligned: 25 Modelled: 25 Confidence: 7.7% Identity: 24% PDB header:hydrolase Chain: G: PDB Molecule:n-acylethanolamine-hydrolyzing acid amidase alpha-subunit; PDBTitle: caenorhabditis elegans n-acylethanolamine-hydrolyzing acid amidase2 (naaa) ortholog Phyre2 PDB 6dy1 chain A Region: 170 - 183 Aligned: 14 Modelled: 14 Confidence: 7.1% Identity: 36% PDB header:hydrolase Chain: A: PDB Molecule:n-acylethanolamine acid amidase alpha-subunit; PDBTitle: rabbit n-acylethanolamine-hydrolyzing acid amidase (naaa) with fatty2 acid (myristate), in presence of triton x-100 Phyre2 PDB 2ajt chain A domain 2 Region: 181 - 200 Aligned: 20 Modelled: 20 Confidence: 6.9% Identity: 15% Fold: FucI/AraA N-terminal and middle domains Superfamily: FucI/AraA N-terminal and middle domains Family: AraA N-terminal and middle domain-like Phyre2 1 d2gs5a1 2 c2muiA_ 3 d2gzoa1 4 c2aj2A_ 5 d2ew0a1 6 d2do8a1 7 d2hafa1 8 c6j4uA_ 9 c6qbyA_ 10 d1vpqa_ 11 d2b78a1 12 c1byyA_ 13 d1sy6a1 14 c4lqlF_ 15 c2zjtB_ 16 d1jl3a_ 17 c4m7vA_ 18 c6dy3G_ 19 c6dy1A_ 20 d2ajta2 21 22 23 24 25 26 27 28 29 30