1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	F	L	A	G	V	L	C	M	C	A	A	A	A	S	A	L	F	G	S	W	S	L	C	H	T	P	T	A	D	P	T	A	L	A	L	R	A	M	A	P	T	Q	L	A	A	A	V	M	L	A	A	G	G	V	V	A	V	A	A
Secondary structure
SS confidence
Disorder		?																																						?	?													?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.
Sequence		P	G	H	T	A	L	M	V	V	I	V	C	I	A	G	A	V	G	T	L	A	A	G	S	W	Q	S	A	Q	Y	A	L	R	R	E	T	A	S	P	T	A	N	C	V	G	S	C	A	V	C	T	Q	A	C	H
Secondary structure
SS confidence
Disorder																							?											?	?	?	?	?	?	?	?	?	?	?	?	?				?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 23%) Alpha helix ( 84%) Beta strand ( 0%)

Rank Aligned region

PDB 2l5b chain A Region: 9 - 26 Aligned: 18 Modelled: 18 Confidence: 20.8% Identity: 39% PDB header:apoptosis Chain: A: PDB Molecule:activator of apoptosis harakiri; PDBTitle: solution structure of the transmembrane domain of bcl-2 member2 harakiri in micelles Phyre2 PDB 4cim chain Q Region: 29 - 39 Aligned: 11 Modelled: 11 Confidence: 10.0% Identity: 64% PDB header:apoptosis Chain: Q: PDB Molecule:bcl-2-like protein 2; PDBTitle: complex of a bcl-w bh3 mutant with a bh3 domain Phyre2 PDB 4cim chain P Region: 29 - 39 Aligned: 11 Modelled: 11 Confidence: 10.0% Identity: 64% PDB header:apoptosis Chain: P: PDB Molecule:bcl-2-like protein 2; PDBTitle: complex of a bcl-w bh3 mutant with a bh3 domain Phyre2 PDB 2k8j chain X Region: 13 - 24 Aligned: 12 Modelled: 12 Confidence: 10.0% Identity: 58% PDB header:viral protein Chain: X: PDB Molecule:p7tm2; PDBTitle: solution structure of hcv p7 tm2 Phyre2 PDB 1m0j chain A Region: 98 - 115 Aligned: 18 Modelled: 18 Confidence: 9.9% Identity: 44% PDB header:metal binding protein Chain: A: PDB Molecule:metallothionein mt_nc; PDBTitle: solution structure of the beta domain of mt_nc Phyre2 PDB 2lqc chain B Region: 78 - 94 Aligned: 17 Modelled: 17 Confidence: 9.1% Identity: 59% PDB header:metal binding protein/transport protein Chain: B: PDB Molecule:voltage-dependent l-type calcium channel subunit alpha-1c; PDBTitle: nmr solution structure of a ca2+-calmodulin with a binding motif2 (nscate) peptide from the n-terminal cytoplasmic domain of the l-type3 voltage-cated calcium channel alpha1c subunit Phyre2 PDB 1zza chain A Region: 67 - 85 Aligned: 19 Modelled: 19 Confidence: 6.5% Identity: 37% PDB header:membrane protein Chain: A: PDB Molecule:stannin; PDBTitle: solution nmr structure of the membrane protein stannin Phyre2 PDB 3gpd chain G domain 1 Region: 106 - 114 Aligned: 9 Modelled: 9 Confidence: 5.8% Identity: 22% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 2msq chain A Region: 102 - 107 Aligned: 6 Modelled: 6 Confidence: 5.8% Identity: 67% PDB header:toxin Chain: A: PDB Molecule:conotoxin cbru9a; PDBTitle: solution study of cbru9a Phyre2 PDB 2pkq chain O domain 1 Region: 90 - 114 Aligned: 25 Modelled: 25 Confidence: 5.8% Identity: 8% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 5gyy chain G Region: 94 - 112 Aligned: 19 Modelled: 19 Confidence: 5.8% Identity: 37% PDB header:plant protein Chain: G: PDB Molecule:s-locus protein 11; PDBTitle: plant receptor complex Phyre2 PDB 2lu2 chain A Region: 49 - 58 Aligned: 10 Modelled: 10 Confidence: 5.7% Identity: 70% PDB header:cell adhesion Chain: A: PDB Molecule:microneme tgmic5 protein; PDBTitle: mic5 regulates the activity of toxoplasma subtilisin 1 by mimicking a2 subtilisin prodomain Phyre2 PDB 2fno chain A domain 1 Region: 19 - 38 Aligned: 20 Modelled: 20 Confidence: 5.3% Identity: 25% Fold: GST C-terminal domain-like Superfamily: GST C-terminal domain-like Family: Glutathione S-transferase (GST), C-terminal domain Phyre2 1 c2l5bA_ 2 c4cimQ_ 3 c4cimP_ 4 c2k8jX_ 5 c1m0jA_ 6 c2lqcB_ 7 c1zzaA_ 8 d3gpdg1 9 c2msqA_ 10 d2pkqo1 11 c5gyyG_ 12 c2lu2A_ 13 d2fnoa1