1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	T	G	A	L	S	Q	S	S	N	I	S	P	L	P	L	A	A	D	L	R	S	A	D	N	R	D	C	P	S	R	T	D	V	L	G	A	A	L	A	N	V	V	G	G	P	V	G	R	H	A	L	I	G	R	T	R	L	M	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																					?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	L	R	V	M	F	A	I	A	L	V	F	L	A	L	G	W	S	T	K	A	A	C	L	Q	S	T	G	T	G	P	G	D	Q	R	V	A	N	W	D	N	Q	R	A	Y	Y	Q	L	C	Y	S	D	T	V	P	L	Y	G	A	E
Secondary structure
SS confidence
Disorder																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	L	S	Q	G	K	F	P	Y	K	S	S	W	I	E	T	D	S	N	G	T	P	Q	L	R	Y	D	G	Q	I	A	V	R	Y	M	E	Y	P	V	L	T	G	I	Y	Q	Y	L	S	M	A	I	A	K	T	Y	T	A	L	S	K
Secondary structure
SS confidence
Disorder																	?	?	?	?	?						?	?	?	?	?	?																					?	?						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	A	P	L	P	V	V	A	E	V	V	M	F	F	N	V	A	A	F	G	L	A	L	A	W	L	T	T	V	W	A	T	S	G	L	A	G	R	R	I	W	D	A	A	L	V	A	A	S	P	L	V	I	F	Q	I	F	T	N	F
Secondary structure
SS confidence
Disorder		?	?		?																													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		D	A	L	A	T	G	L	A	T	S	G	L	L	A	W	A	R	R	R	P	V	L	A	G	V	L	I	G	L	G	S	A	A	K	L	Y	P	L	L	F	L	Y	P	L	L	L	L	G	I	R	A	G	R	L	N	A	L	A	R	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		M	A	A	A	A	A	T	W	L	L	V	N	L	P	V	M	L	L	F	P	R	G	W	S	E	F	F	R	L	N	T	R	R	G	D	D	M	D	S	L	Y	N	V	V	K	S	F	T	G	W	R	G	F	D	P	T	L	G	F	W
Secondary structure
SS confidence
Disorder																																																?	?		?	?	?	?	?			?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		E	P	P	L	V	L	N	T	V	V	T	L	L	F	V	L	C	C	A	A	I	A	Y	I	A	L	T	A	P	H	R	P	R	V	A	Q	L	T	F	L	T	V	A	S	F	L	L	V	N	K	V	W	S	P	Q	F	S	L	W	L
Secondary structure
SS confidence
Disorder		?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		V	P	L	A	V	L	A	L	P	H	R	R	I	L	L	A	W	M	T	I	D	A	L	V	W	V	P	R	M	Y	Y	L	Y	G	N	P	S	R	S	L	P	E	Q	W	F	T	T	T	V	L	L	R	D	I	A	V	M	V	L	C
Secondary structure
SS confidence
Disorder																																					?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		G	L	V	V	W	Q	I	Y	R	P	G	R	D	L	V	R	T	G	G	P	G	A	L	P	A	C	G	G	V	D	D	P	V	G	G	V	F	A	N	A	A	D	A	P	P	G	R	L	P	S	W	L	R	P	R	L	G	D	E	H
Secondary structure
SS confidence
Disorder																	?	?		?	?	?	?	?	?	?	?	?																?				?	?				?		?			?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence		A	R	E	R	T	P	D	A	G	R	D	R	T	F	S	G	Q	H	R	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 19%) Alpha helix ( 57%) Beta strand ( 0%) TM helix ( 41%) (View membrane topology prediction)

Rank Aligned region

PDB 5f15 chain A Region: 123 - 493 Aligned: 326 Modelled: 338 Confidence: 99.0% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:4-amino-4-deoxy-l-arabinose (l-ara4n) transferase; PDBTitle: crystal structure of arnt from cupriavidus metallidurans bound to2 undecaprenyl phosphate Phyre2 PDB 6p25 chain A Region: 66 - 339 Aligned: 231 Modelled: 231 Confidence: 98.0% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:dolichyl-phosphate-mannose--protein mannosyltransferase 1; PDBTitle: structure of s. cerevisiae protein o-mannosyltransferase pmt1-pmt22 complex bound to the sugar donor and a peptide acceptor Phyre2 PDB 6p2r chain B Region: 66 - 339 Aligned: 231 Modelled: 231 Confidence: 97.8% Identity: 13% PDB header:transferase Chain: B: PDB Molecule:dolichyl-phosphate-mannose--protein mannosyltransferase 2; PDBTitle: structure of s. cerevisiae protein o-mannosyltransferase pmt1-pmt22 complex bound to the sugar donor Phyre2 PDB 3waj chain A Region: 152 - 473 Aligned: 313 Modelled: 322 Confidence: 97.2% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:transmembrane oligosaccharyl transferase; PDBTitle: crystal structure of the archaeoglobus fulgidus2 oligosaccharyltransferase (o29867_arcfu) complex with zn and sulfate Phyre2 PDB 6ezn chain F Region: 111 - 487 Aligned: 347 Modelled: 361 Confidence: 65.3% Identity: 12% PDB header:membrane protein Chain: F: PDB Molecule:dolichyl-diphosphooligosaccharide--protein PDBTitle: cryo-em structure of the yeast oligosaccharyltransferase (ost) complex Phyre2 PDB 3rce chain A Region: 156 - 473 Aligned: 302 Modelled: 318 Confidence: 49.3% Identity: 13% PDB header:transferase/peptide Chain: A: PDB Molecule:oligosaccharide transferase to n-glycosylate proteins; PDBTitle: bacterial oligosaccharyltransferase pglb Phyre2 PDB 5zih chain A Region: 409 - 496 Aligned: 88 Modelled: 88 Confidence: 35.0% Identity: 13% PDB header:membrane protein Chain: A: PDB Molecule:sensory opsin a,chrimson; PDBTitle: crystal structure of the red light-activated channelrhodopsin2 chrimson. Phyre2 PDB 1xio chain A Region: 361 - 497 Aligned: 137 Modelled: 137 Confidence: 20.9% Identity: 9% Fold: Family A G protein-coupled receptor-like Superfamily: Family A G protein-coupled receptor-like Family: Bacteriorhodopsin-like Phyre2 PDB 1xio chain A Region: 361 - 497 Aligned: 137 Modelled: 137 Confidence: 20.9% Identity: 9% PDB header:signaling protein Chain: A: PDB Molecule:anabaena sensory rhodopsin; PDBTitle: anabaena sensory rhodopsin Phyre2 PDB 3ug9 chain A Region: 409 - 496 Aligned: 88 Modelled: 88 Confidence: 18.6% Identity: 9% PDB header:membrane protein Chain: A: PDB Molecule:archaeal-type opsin 1, archaeal-type opsin 2; PDBTitle: crystal structure of the closed state of channelrhodopsin Phyre2 PDB 3dcg chain F Region: 409 - 417 Aligned: 9 Modelled: 9 Confidence: 9.5% Identity: 56% PDB header:ligase/viral protein Chain: F: PDB Molecule:virion infectivity factor; PDBTitle: crystal structure of the hiv vif bc-box in complex with human elonginb2 and elonginc Phyre2 PDB 5v77 chain B Region: 120 - 157 Aligned: 23 Modelled: 23 Confidence: 8.6% Identity: 30% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an uncharacterized protein from neisseria2 gonorrhoeae Phyre2 PDB 6et5 chain B Region: 59 - 99 Aligned: 33 Modelled: 41 Confidence: 7.9% Identity: 24% PDB header:photosynthesis Chain: B: PDB Molecule: PDBTitle: reaction centre light harvesting complex 1 from blc. virids Phyre2 PDB 3fnk chain A Region: 93 - 115 Aligned: 21 Modelled: 23 Confidence: 6.8% Identity: 29% PDB header:structural protein Chain: A: PDB Molecule:cellulosomal scaffoldin adaptor protein b; PDBTitle: crystal structure of the second type ii cohesin module from the2 cellulosomal adaptor scaa scaffoldin of acetivibrio cellulolyticus Phyre2 PDB 1mje chain B Region: 547 - 560 Aligned: 14 Modelled: 14 Confidence: 6.8% Identity: 50% PDB header:gene regulation/antitumor protein/dna Chain: B: PDB Molecule:deleted in split hand/split foot protein 1; PDBTitle: structure of a brca2-dss1-ssdna complex Phyre2 PDB 1xrd chain A domain 1 Region: 58 - 111 Aligned: 46 Modelled: 54 Confidence: 6.7% Identity: 17% Fold: Light-harvesting complex subunits Superfamily: Light-harvesting complex subunits Family: Light-harvesting complex subunits Phyre2 PDB 1xrd chain A Region: 58 - 111 Aligned: 46 Modelled: 54 Confidence: 6.7% Identity: 17% PDB header:membrane protein Chain: A: PDB Molecule:light-harvesting protein b-880, alpha chain; PDBTitle: light-harvesting complex 1 alfa subunit from wild-type2 rhodospirillum rubrum Phyre2 PDB 1nyc chain A Region: 78 - 105 Aligned: 18 Modelled: 28 Confidence: 6.6% Identity: 33% Fold: Streptavidin-like Superfamily: beta-Barrel protease inhibitors Family: Staphostatin Phyre2 PDB 3zue chain B Region: 109 - 133 Aligned: 25 Modelled: 25 Confidence: 6.4% Identity: 24% PDB header:virus Chain: B: PDB Molecule:capsid structural protein vp60; PDBTitle: rabbit hemorrhagic disease virus (rhdv)capsid protein Phyre2 PDB 5gy6 chain A Region: 151 - 162 Aligned: 12 Modelled: 12 Confidence: 6.4% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:ribonuclease t1; PDBTitle: ribonuclease from hericium erinaceus (rnase he1) Phyre2 1 c5f15A_ 2 c6p25A_ 3 c6p2rB_ 4 c3wajA_ 5 c6eznF_ 6 c3rceA_ 7 c5zihA_ 8 d1xioa_ 9 c1xioA_ 10 c3ug9A_ 11 c3dcgF_ 12 c5v77B_ 13 c6et5b_ 14 c3fnkA_ 15 c1mjeB_ 16 d1xrda1 17 c1xrdA_ 18 d1nyca_ 19 c3zueB_ 20 c5gy6A_ 21 22 23 24 25 26 27 28