1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	K	S	S	K	R	R	P	A	P	E	K	P	V	K	T	R	K	C	V	F	C	A	K	K	D	Q	A	I	D	Y	K	D	T	A	L	L	R	T	Y	I	S	E	R	G	K	I	R	A	R	R	V	T	G	N	C	V	Q	H
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																													?									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.
Sequence		Q	R	D	I	A	L	A	V	K	N	A	R	E	V	A	L	L	P	F	T	S	S	V	R
Secondary structure
SS confidence
Disorder																						?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 27%) Alpha helix ( 33%) Beta strand ( 2%)

Rank Aligned region

PDB 3j0x chain U Region: 12 - 84 Aligned: 73 Modelled: 73 Confidence: 100.0% Identity: 42% PDB header:ribosome Chain: U: PDB Molecule:30s ribosomal protein s18; PDBTitle: structural characterization of mrna-trna translocation intermediates2 (30s ribosome of class 4b of the six classes) Phyre2 PDB 5o5j chain R Region: 17 - 81 Aligned: 65 Modelled: 65 Confidence: 100.0% Identity: 92% PDB header:ribosome Chain: R: PDB Molecule:30s ribosomal protein s18 2; PDBTitle: structure of the 30s small ribosomal subunit from mycobacterium2 smegmatis Phyre2 PDB 6dzk chain R Region: 1 - 81 Aligned: 80 Modelled: 81 Confidence: 100.0% Identity: 54% PDB header:ribosome Chain: R: PDB Molecule: PDBTitle: cryo-em structure of mycobacterium smegmatis c(minus) 30s ribosomal2 subunit with mpy Phyre2 PDB 5aj3 chain P Region: 5 - 80 Aligned: 76 Modelled: 76 Confidence: 100.0% Identity: 26% PDB header:ribosome Chain: P: PDB Molecule:mitoribosomal protein bs16m, mrps16; PDBTitle: structure of the small subunit of the mammalian mitoribosome Phyre2 PDB 3j6v chain R Region: 5 - 79 Aligned: 75 Modelled: 75 Confidence: 100.0% Identity: 29% PDB header:ribosome Chain: R: PDB Molecule:28s ribosomal protein s18a, mitochondrial; PDBTitle: cryo-em structure of the small subunit of the mammalian mitochondrial2 ribosome Phyre2 PDB 1i94 chain R Region: 5 - 83 Aligned: 78 Modelled: 79 Confidence: 99.9% Identity: 33% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Ribosomal protein S18 Family: Ribosomal protein S18 Phyre2 PDB 5aj3 chain R Region: 2 - 84 Aligned: 80 Modelled: 83 Confidence: 99.9% Identity: 31% PDB header:ribosome Chain: R: PDB Molecule:mitoribosomal protein bs18m, mrps18c; PDBTitle: structure of the small subunit of the mammalian mitoribosome Phyre2 PDB 2uub chain R domain 1 Region: 17 - 83 Aligned: 67 Modelled: 67 Confidence: 99.9% Identity: 36% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Ribosomal protein S18 Family: Ribosomal protein S18 Phyre2 PDB 3bbn chain R Region: 28 - 84 Aligned: 57 Modelled: 57 Confidence: 99.9% Identity: 42% PDB header:ribosome Chain: R: PDB Molecule:ribosomal protein s18; PDBTitle: homology model for the spinach chloroplast 30s subunit fitted to 9.4a2 cryo-em map of the 70s chlororibosome. Phyre2 PDB 2qal chain R domain 1 Region: 29 - 83 Aligned: 55 Modelled: 55 Confidence: 99.9% Identity: 49% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Ribosomal protein S18 Family: Ribosomal protein S18 Phyre2 PDB 3df1 chain R Region: 29 - 83 Aligned: 55 Modelled: 55 Confidence: 99.9% Identity: 49% PDB header:ribosome Chain: R: PDB Molecule:30s ribosomal protein s18; PDBTitle: crystal structure of the bacterial ribosome from escherichia coli in2 complex with hygromycin b. this file contains the 30s subunit of the3 first 70s ribosome, with hygromycin b bound. the entire crystal4 structure contains two 70s ribosomes. Phyre2 PDB 1g1x chain C Region: 28 - 80 Aligned: 46 Modelled: 53 Confidence: 99.8% Identity: 41% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Ribosomal protein S18 Family: Ribosomal protein S18 Phyre2 PDB 6drd chain A Region: 22 - 56 Aligned: 32 Modelled: 35 Confidence: 21.6% Identity: 28% PDB header:transferase Chain: A: PDB Molecule:dna-directed rna polymerase ii subunit rpb1; PDBTitle: rna pol ii(g) Phyre2 PDB 2aam chain A Region: 62 - 81 Aligned: 20 Modelled: 20 Confidence: 21.3% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:hypothetical protein tm1410; PDBTitle: crystal structure of a putative glycosidase (tm1410) from thermotoga2 maritima at 2.20 a resolution Phyre2 PDB 2aam chain A domain 1 Region: 62 - 81 Aligned: 20 Modelled: 20 Confidence: 21.3% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: (Trans)glycosidases Family: TM1410-like Phyre2 PDB 2wb1 chain Y Region: 22 - 56 Aligned: 34 Modelled: 35 Confidence: 18.0% Identity: 15% PDB header:transcription Chain: Y: PDB Molecule:dna-directed rna polymerase rpo1c subunit; PDBTitle: the complete structure of the archaeal 13-subunit dna-2 directed rna polymerase Phyre2 PDB 2pmz chain G Region: 22 - 57 Aligned: 35 Modelled: 36 Confidence: 17.3% Identity: 14% PDB header:translation, transferase Chain: G: PDB Molecule:dna-directed rna polymerase subunit a"; PDBTitle: archaeal rna polymerase from sulfolobus solfataricus Phyre2 PDB 5tcb chain A Region: 63 - 81 Aligned: 19 Modelled: 19 Confidence: 15.9% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:pela; PDBTitle: structure of the glycoside hydrolase domain of pela from pseudomonas2 aeruginosa Phyre2 PDB 1wii chain A Region: 2 - 23 Aligned: 22 Modelled: 22 Confidence: 14.4% Identity: 41% Fold: Rubredoxin-like Superfamily: Zinc beta-ribbon Family: Putative zinc binding domain Phyre2 PDB 2k6x chain A Region: 58 - 79 Aligned: 22 Modelled: 22 Confidence: 13.7% Identity: 14% PDB header:transcription Chain: A: PDB Molecule:rna polymerase sigma factor rpod; PDBTitle: autoregulation of a group 1 bacterial sigma factor involves2 the formation of a region 1.1- induced compacted structure Phyre2 1 c3j0xU_ 2 c5o5jR_ 3 c6dzkr_ 4 c5aj3p_ 5 c3j6vR_ 6 d1i94r_ 7 c5aj3R_ 8 d2uubr1 9 c3bbnR_ 10 d2qalr1 11 c3df1R_ 12 d1g1xc_ 13 c6drdA_ 14 c2aamA_ 15 d2aama1 16 c2wb1Y_ 17 c2pmzG_ 18 c5tcbA_ 19 d1wiia_ 20 c2k6xA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43