1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	R	R	T	G	Q	R	W	R	G	T	L	P	G	R	R	P	W	T	R	P	A	P	A	T	C	R	R	H	L	A	F	V	E	L	R	H	Y	F	A	R	V	M	S	S	A	I	G	S	V	A	R	W	I	V	P	L	L	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?		?	?	?	?		?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	A	A	V	A	S	I	G	V	I	A	D	P	V	R	V	V	R	A	P	A	L	I	L	V	D	A	A	N	P	L	A	G	K	P	F	Y	V	D	P	A	S	A	A	M	V	A	A	R	N	A	N	P	P	N	A	E	L	T	S
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																					?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	A	N	T	P	Q	S	Y	W	L	D	Q	A	F	P	P	A	T	V	G	G	T	V	A	R	Y	T	G	A	A	Q	A	A	G	A	M	P	V	L	T	L	Y	G	I	P	H	R	D	C	G	S	Y	A	S	G	G	F	A	T	G
Secondary structure
SS confidence
Disorder			?	?																																														?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	D	Y	R	G	W	I	D	A	V	A	S	G	L	G	S	S	P	A	T	I	I	V	E	P	D	A	L	A	M	A	D	C	L	S	P	D	Q	R	Q	E	R	F	D	L	V	R	Y	A	V	D	T	L	T	R	D	P	A	A	A
Secondary structure
SS confidence
Disorder																																	?	?	?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		V	Y	V	D	A	G	H	S	R	W	L	S	A	E	A	M	A	A	R	L	N	D	V	G	V	G	R	A	R	G	F	S	L	N	V	S	N	F	Y	T	T	D	E	E	I	G	Y	G	E	A	I	S	G	L	T	N	G	S	H	Y
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		V	I	D	T	S	R	N	G	A	G	P	A	P	D	A	P	L	N	W	C	N	P	S	G	R	A	L	G	A	P	P	T	T	A	T	A	G	A	H	A	D	A	Y	L	W	I	K	R	P	G	E	S	D	G	T	C	G	R	G	E
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?	?																			?																				?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380
Sequence		P	Q	A	G	R	F	V	S	Q	Y	A	I	D	L	A	H	N	A	G	Q
Secondary structure
SS confidence
Disorder		?	?															?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 22%) Alpha helix ( 37%) Beta strand ( 9%)

Rank Aligned region

PDB 1uoz chain A Region: 83 - 380 Aligned: 298 Modelled: 298 Confidence: 100.0% Identity: 99% Fold: 7-stranded beta/alpha barrel Superfamily: Glycosyl hydrolases family 6, cellulases Family: Glycosyl hydrolases family 6, cellulases Phyre2 PDB 5xyh chain A Region: 85 - 378 Aligned: 293 Modelled: 294 Confidence: 100.0% Identity: 34% PDB header:hydrolase Chain: A: PDB Molecule:cbsa; PDBTitle: crystal structure of catalytic domain of 1,4-beta-cellobiosidase2 (cbsa) from xanthomonas oryzae pv. oryzae Phyre2 PDB 3voh chain A Region: 86 - 378 Aligned: 292 Modelled: 293 Confidence: 100.0% Identity: 33% PDB header:hydrolase Chain: A: PDB Molecule:cellobiohydrolase; PDBTitle: cccel6a catalytic domain complexed with cellobiose Phyre2 PDB 1qjw chain A Region: 84 - 378 Aligned: 294 Modelled: 295 Confidence: 100.0% Identity: 30% Fold: 7-stranded beta/alpha barrel Superfamily: Glycosyl hydrolases family 6, cellulases Family: Glycosyl hydrolases family 6, cellulases Phyre2 PDB 5xcz chain A Region: 86 - 378 Aligned: 292 Modelled: 293 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: A: PDB Molecule:glucanase; PDBTitle: structure of the cellobiohydrolase cel6a from phanerochaete2 chrysosporium in complex with cellobiose at 2.1 angstrom Phyre2 PDB 1oc7 chain A Region: 84 - 378 Aligned: 294 Modelled: 295 Confidence: 100.0% Identity: 30% Fold: 7-stranded beta/alpha barrel Superfamily: Glycosyl hydrolases family 6, cellulases Family: Glycosyl hydrolases family 6, cellulases Phyre2 PDB 1dys chain A Region: 88 - 378 Aligned: 289 Modelled: 291 Confidence: 100.0% Identity: 30% Fold: 7-stranded beta/alpha barrel Superfamily: Glycosyl hydrolases family 6, cellulases Family: Glycosyl hydrolases family 6, cellulases Phyre2 PDB 3a64 chain A Region: 89 - 378 Aligned: 289 Modelled: 290 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: A: PDB Molecule:cellobiohydrolase; PDBTitle: crystal structure of cccel6c, a glycoside hydrolase family 62 enzyme, from coprinopsis cinerea Phyre2 PDB 4b4f chain B Region: 86 - 378 Aligned: 286 Modelled: 293 Confidence: 100.0% Identity: 34% PDB header:hydrolase Chain: B: PDB Molecule:beta-1,4-exocellulase; PDBTitle: thermobifida fusca cel6b(e3) co-crystallized with cellobiose Phyre2 PDB 5jx6 chain C Region: 86 - 378 Aligned: 283 Modelled: 293 Confidence: 100.0% Identity: 31% PDB header:hydrolase Chain: C: PDB Molecule:glucanase; PDBTitle: gh6 orpinomyces sp. y102 enzyme Phyre2 PDB 6fao chain A Region: 94 - 379 Aligned: 277 Modelled: 286 Confidence: 100.0% Identity: 48% PDB header:hydrolase Chain: A: PDB Molecule:glycoside hydrolase family 6; PDBTitle: discovery and characterization of a thermostable gh6 endoglucanase2 from a compost metagenome Phyre2 PDB 2bod chain X domain 1 Region: 88 - 378 Aligned: 272 Modelled: 291 Confidence: 100.0% Identity: 43% Fold: 7-stranded beta/alpha barrel Superfamily: Glycosyl hydrolases family 6, cellulases Family: Glycosyl hydrolases family 6, cellulases Phyre2 PDB 4w86 chain B Region: 141 - 204 Aligned: 64 Modelled: 61 Confidence: 61.6% Identity: 11% PDB header:hydrolase Chain: B: PDB Molecule:xyloglucan-specific endo-beta-1,4-glucanase; PDBTitle: crystal structure of xeg5a, a gh5 xyloglucan-specific endo-beta-1,4-2 glucanase from ruminal metagenomic library, in complex with glucose3 and tris Phyre2 PDB 4w7w chain A Region: 141 - 246 Aligned: 100 Modelled: 106 Confidence: 56.5% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:cellulase; PDBTitle: high-resolution structure of xaccel5a in complex with cellopentaose Phyre2 PDB 3w0k chain A Region: 142 - 244 Aligned: 103 Modelled: 103 Confidence: 50.9% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:bifunctional endomannanase/endoglucanase; PDBTitle: crystal structure of a glycoside hydrolase Phyre2 PDB 4lx4 chain D Region: 142 - 244 Aligned: 97 Modelled: 103 Confidence: 50.1% Identity: 10% PDB header:hydrolase Chain: D: PDB Molecule:endoglucanase(endo-1,4-beta-glucanase)protein; PDBTitle: crystal structure determination of pseudomonas stutzeri endoglucanase2 cel5a using a twinned data set Phyre2 PDB 5tnv chain A Region: 142 - 264 Aligned: 113 Modelled: 123 Confidence: 47.2% Identity: 13% PDB header:isomerase Chain: A: PDB Molecule:ap endonuclease, family protein 2; PDBTitle: crystal structure of a xylose isomerase-like tim barrel protein from2 mycobacterium smegmatis in complex with magnesium Phyre2 PDB 3ne8 chain A Region: 237 - 308 Aligned: 54 Modelled: 54 Confidence: 46.1% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:n-acetylmuramoyl-l-alanine amidase; PDBTitle: the crystal structure of a domain from n-acetylmuramoyl-l-alanine2 amidase of bartonella henselae str. houston-1 Phyre2 PDB 4ee9 chain A Region: 141 - 244 Aligned: 99 Modelled: 104 Confidence: 43.7% Identity: 8% PDB header:hydrolase Chain: A: PDB Molecule:endoglucanase; PDBTitle: crystal structure of the rbcel1 endo-1,4-glucanase Phyre2 PDB 3u7b chain B Region: 141 - 274 Aligned: 132 Modelled: 134 Confidence: 40.4% Identity: 20% PDB header:hydrolase Chain: B: PDB Molecule:endo-1,4-beta-xylanase; PDBTitle: a new crystal structure of a fusarium oxysporum gh10 xylanase reveals2 the presence of an extended loop on top of the catalytic cleft Phyre2 1 d1uoza_ 2 c5xyhA_ 3 c3vohA_ 4 d1qjwa_ 5 c5xczA_ 6 d1oc7a_ 7 d1dysa_ 8 c3a64A_ 9 c4b4fB_ 10 c5jx6C_ 11 c6faoA_ 12 d2bodx1 13 c4w86B_ 14 c4w7wA_ 15 c3w0kA_ 16 c4lx4D_ 17 c5tnvA_ 18 c3ne8A_ 19 c4ee9A_ 20 c3u7bB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99