1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	Q	R	E	I	Y	D	G	E	A	R	L	S	W	V	L	A	A	L	A	G	I	L	G	A	T	A	F	T	H	S	A	G	Y	F	V	T	F	M	T	G	N	S	Q	R	A	V	L	G	L	F	G	D	D	A	W	M	S	V	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	S	L	L	I	L	F	F	V	A	G	V	V	I	A	S	V	C	R	R	H	F	W	A	A	H	P	H	G	P	T	V	L	T	T	F	S	L	I	F	A	A	G	V	D	I	M	L	G	G	W	H	E	S	M	L	D	F	V	P
Secondary structure
SS confidence
Disorder																										?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	L	F	V	V	F	G	I	G	A	L	N	T	S	F	V	K	D	G	E	V	S	V	P	L	S	Y	V	T	G	T	L	V	K	M	G	Q	G	I	E	R	H	L	A	G	G	K	V	E	D	W	L	G	Y	F	L	L	H	A	S
Secondary structure
SS confidence
Disorder																				?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		F	V	L	G	A	A	A	G	G	A	I	S	M	V	V	T	G	P	Q	M	L	A	V	A	A	V	V	C	A	A	T	T	G	Y	T	Y	L	H	A	D	R	R	G	L	V	N	Q	K	R	P	Q	P	G	K	R	L	F	R	A	L
Secondary structure
SS confidence
Disorder																																										?	?	?	?	?	?	?	?	?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.
Sequence		R	R	G	E	L	D	S	G	T	S	T	P	A	T	N	Y	G	S	S
Secondary structure
SS confidence
Disorder			?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 15%) Alpha helix ( 81%) Beta strand ( 0%) TM helix ( 56%) (View membrane topology prediction)

Rank Aligned region

PDB 3wdo chain A Region: 34 - 249 Aligned: 194 Modelled: 194 Confidence: 81.7% Identity: 13% PDB header:transport protein Chain: A: PDB Molecule:mfs transporter; PDBTitle: structure of e. coli yajr transporter Phyre2 PDB 5edl chain A Region: 125 - 248 Aligned: 120 Modelled: 124 Confidence: 75.9% Identity: 15% PDB header:transport protein Chain: A: PDB Molecule:putative hmp/thiamine permease protein ykoe; PDBTitle: crystal structure of an s-component of ecf transporter Phyre2 PDB 4w6v chain A Region: 2 - 246 Aligned: 217 Modelled: 225 Confidence: 73.0% Identity: 15% PDB header:transport protein Chain: A: PDB Molecule:di-/tripeptide transporter; PDBTitle: crystal structure of a peptide transporter from yersinia2 enterocolitica at 3 a resolution Phyre2 PDB 5ayn chain A Region: 35 - 219 Aligned: 167 Modelled: 168 Confidence: 58.4% Identity: 11% PDB header:transport protein Chain: A: PDB Molecule:solute carrier family 39 (iron-regulated transporter); PDBTitle: crystal structure of a bacterial homologue of iron transporter2 ferroportin in outward-facing state Phyre2 PDB 1pv7 chain A Region: 34 - 235 Aligned: 185 Modelled: 185 Confidence: 52.8% Identity: 11% Fold: MFS general substrate transporter Superfamily: MFS general substrate transporter Family: LacY-like proton/sugar symporter Phyre2 PDB 1pv7 chain B Region: 34 - 235 Aligned: 185 Modelled: 185 Confidence: 52.8% Identity: 11% PDB header:transport protein Chain: B: PDB Molecule:lactose permease; PDBTitle: crystal structure of lactose permease with tdg Phyre2 PDB 5aym chain A Region: 35 - 219 Aligned: 167 Modelled: 167 Confidence: 51.4% Identity: 11% PDB header:transport protein Chain: A: PDB Molecule:solute carrier family 39 (iron-regulated transporter); PDBTitle: crystal structure of a bacterial homologue of iron transporter2 ferroportin in outward-facing state with soaked iron Phyre2 PDB 1lda chain A Region: 14 - 198 Aligned: 176 Modelled: 185 Confidence: 51.1% Identity: 17% PDB header:transport protein Chain: A: PDB Molecule:glycerol uptake facilitator protein; PDBTitle: crystal structure of the e. coli glycerol facilitator (glpf) without2 substrate glycerol Phyre2 PDB 1fx8 chain A Region: 14 - 198 Aligned: 176 Modelled: 185 Confidence: 51.1% Identity: 17% Fold: Aquaporin-like Superfamily: Aquaporin-like Family: Aquaporin-like Phyre2 PDB 4zp0 chain A Region: 34 - 246 Aligned: 191 Modelled: 197 Confidence: 47.4% Identity: 10% PDB header:transport protein Chain: A: PDB Molecule:multidrug transporter mdfa; PDBTitle: crystal structure of e. coli multidrug transporter mdfa in complex2 with deoxycholate Phyre2 PDB 6h7d chain A Region: 13 - 246 Aligned: 206 Modelled: 218 Confidence: 44.0% Identity: 12% PDB header:membrane protein Chain: A: PDB Molecule:sugar transport protein 10; PDBTitle: crystal structure of a. thaliana sugar transport protein 10 in complex2 with glucose in the outward occluded state Phyre2 PDB 1bcc chain E domain 2 Region: 2 - 40 Aligned: 39 Modelled: 39 Confidence: 43.9% Identity: 23% Fold: Single transmembrane helix Superfamily: ISP transmembrane anchor Family: ISP transmembrane anchor Phyre2 PDB 6e9o chain A Region: 10 - 252 Aligned: 205 Modelled: 227 Confidence: 39.3% Identity: 7% PDB header:membrane protein Chain: A: PDB Molecule:d-galactonate transport; PDBTitle: e. coli d-galactonate:proton symporter mutant e133q in the outward2 substrate-bound form Phyre2 PDB 4xjn chain M Region: 110 - 166 Aligned: 52 Modelled: 57 Confidence: 39.2% Identity: 19% PDB header:viral protein/rna Chain: M: PDB Molecule:nucleocapsid; PDBTitle: structure of the parainfluenza virus 5 nucleocapsid-rna complex: an2 insight into paramyxovirus polymerase activity Phyre2 PDB 4lds chain B Region: 14 - 246 Aligned: 198 Modelled: 216 Confidence: 35.3% Identity: 13% PDB header:transport protein, membrane protein Chain: B: PDB Molecule:bicyclomycin resistance protein tcab; PDBTitle: the inward-facing structure of the glucose transporter from2 staphylococcus epidermidis Phyre2 PDB 5tsa chain A Region: 8 - 218 Aligned: 174 Modelled: 175 Confidence: 32.7% Identity: 14% PDB header:metal binding protein Chain: A: PDB Molecule:membrane protein; PDBTitle: crystal structure of the zrt-/irt-like protein from bordetella2 bronchiseptica with bound zn2+ Phyre2 PDB 3c02 chain A Region: 14 - 200 Aligned: 178 Modelled: 187 Confidence: 29.6% Identity: 12% PDB header:membrane protein Chain: A: PDB Molecule:aquaglyceroporin; PDBTitle: x-ray structure of the aquaglyceroporin from plasmodium falciparum Phyre2 PDB 2f2b chain A Region: 14 - 195 Aligned: 172 Modelled: 179 Confidence: 29.4% Identity: 11% PDB header:membrane protein Chain: A: PDB Molecule:aquaporin aqpm; PDBTitle: crystal structure of integral membrane protein aquaporin aqpm at 1.68a2 resolution Phyre2 PDB 5v2s chain A Region: 183 - 253 Aligned: 64 Modelled: 71 Confidence: 27.4% Identity: 17% PDB header:viral protein Chain: A: PDB Molecule:envelope glycoprotein b; PDBTitle: crystal structure of glycoprotein b from herpes simplex virus type i Phyre2 PDB 4uft chain B Region: 110 - 166 Aligned: 52 Modelled: 57 Confidence: 27.3% Identity: 23% PDB header:rna binding protein Chain: B: PDB Molecule:nucleoprotein; PDBTitle: structure of the helical measles virus nucleocapsid Phyre2 1 c3wdoA_ 2 c5edlA_ 3 c4w6vA_ 4 c5aynA_ 5 d1pv7a_ 6 c1pv7B_ 7 c5aymA_ 8 c1ldaA_ 9 d1fx8a_ 10 c4zp0A_ 11 c6h7dA_ 12 d1bcce2 13 c6e9oA_ 14 c4xjnM_ 15 c4ldsB_ 16 c5tsaA_ 17 c3c02A_ 18 c2f2bA_ 19 c5v2sA_ 20 c4uftB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72