1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	P	F	G	F	T	P	K	A	R	H	N	R	G	V	A	L	R	S	T	Y	R	L	D	G	W	V	M	G	P	V	D	K	E	G	W	G	L	S	Y	V	F	A	Q	P	S	V	L	A	A	A	A	T	D	L	A	G	I	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?							?				?						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	A	I	N	Q	A	T	A	A	V	A	A	P	T	T	G	L	A	A	A	A	A	D	E	V	S	T	A	L	A	T	L	F	G	A	Y	G	Q	Q	F	Q	A	I	S	A	Q	V	A	A	F	H	N	E	F	T	Q	R	L	A	A
Secondary structure
SS confidence
Disorder						?	?		?												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	A	N	A	F	V	N	A	E	A	T	N	T	S	A	L	V	Q	E	A	T	A	G	L	F	K	P	T	S	P	P	V	L	P	P	M	F	N	Q	N	T	A	I	I	M	G	G	T	G	S	P	I	P	T	P	S	Y	V	N	A
Secondary structure
SS confidence
Disorder			?											?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		I	T	T	L	F	I	D	P	V	V	S	N	P	V	V	K	A	L	V	T	P	E	E	L	Y	P	I	T	G	V	K	S	L	P	F	Q	T	S	V	Q	L	G	L	Q	I	L	D	G	A	I	W	E	Q	I	N	A	G	N	H	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		T	V	F	G	Y	S	Q	S	A	V	I	A	S	L	E	M	Q	H	L	I	S	L	G	P	N	A	P	S	P	S	Q	L	N	F	I	L	I	G	N	E	M	N	P	N	G	G	I	L	A	R	I	P	G	L	N	V	T	T	L	G
Secondary structure
SS confidence
Disorder																								?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		L	P	F	Y	G	A	T	P	D	N	P	Y	P	T	T	T	Y	T	L	E	Y	D	G	F	A	D	F	P	R	Y	P	L	N	V	L	S	D	I	N	A	V	F	G	I	L	T	V	H	T	T	Y	A	D	L	T	P	A	Q	I	A
Secondary structure
SS confidence
Disorder				?	?																																																				?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		S	A	T	Q	L	P	T	Q	G	T	T	S	N	T	Y	Y	I	I	E	T	E	H	L	P	L	L	A	P	L	R	A	I	P	V	I	G	P	P	L	A	A	L	V	E	P	N	L	E	V	I	V	N	L	G	Y	G	D	P	R	F
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		G	Y	S	T	S	P	A	N	V	P	T	P	F	G	L	F	P	D	V	P	A	S	V	V	A	D	A	L	V	A	G	T	Q	Q	G	V	N	D	F	M	V	E	L	P	A	A	L	N	T	L	P	Q	T	P	M	P	A	F	P	P
Secondary structure
SS confidence
Disorder		?	?	?					?										?				?		?	?	?															?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		Y	V	P	T	L	L	P	P	P	P	P	P	Q	P	A	T	L	I	N	I	A	D	T	F	A	S	V	V	S	T	G	Y	S	I	L	L	P	T	A	D	L	G	L	A	F	V	T	I	L	P	A	Y	D	L	T	L	F	V	N	Q
Secondary structure
SS confidence
Disorder		?	?	?			?	?	?	?	?	?	?	?	?	?		?	?				?	?	?	?	?	?	?	?	?	?	?		?		?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.
Sequence		L	A	A	G	N	L	R	A	A	I	E	L	P	L	A	A	T	I	G	L	A	A	L	G	G	M	I	E	F	I	A	I	V	V	T	L	A	D	I	T	Q	Q	L	Q	S	F	S	I
Secondary structure
SS confidence
Disorder																										?																				?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 21%) Alpha helix ( 43%) Beta strand ( 8%)

Rank Aligned region

PDB 5xfs chain A Region: 45 - 122 Aligned: 78 Modelled: 78 Confidence: 100.0% Identity: 47% PDB header:protein transport Chain: A: PDB Molecule:pe family protein pe8; PDBTitle: crystal structure of pe8-ppe15 in complex with espg5 from m.2 tuberculosis Phyre2 PDB 2g38 chain A Region: 46 - 122 Aligned: 77 Modelled: 77 Confidence: 100.0% Identity: 34% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:pe family protein; PDBTitle: a pe/ppe protein complex from mycobacterium tuberculosis Phyre2 PDB 2g38 chain A domain 1 Region: 46 - 122 Aligned: 77 Modelled: 77 Confidence: 100.0% Identity: 34% Fold: Ferritin-like Superfamily: PE/PPE dimer-like Family: PE Phyre2 PDB 3aja chain A Region: 161 - 355 Aligned: 194 Modelled: 195 Confidence: 99.8% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of msmeg_6394 Phyre2 PDB 3hc7 chain A Region: 161 - 329 Aligned: 156 Modelled: 169 Confidence: 99.1% Identity: 22% PDB header:cell adhesion Chain: A: PDB Molecule:gene 12 protein; PDBTitle: crystal structure of lysin b from mycobacteriophage d29 Phyre2 PDB 1qoz chain A Region: 161 - 331 Aligned: 167 Modelled: 171 Confidence: 99.1% Identity: 16% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 1g66 chain A Region: 161 - 326 Aligned: 162 Modelled: 166 Confidence: 99.0% Identity: 13% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 2czq chain B Region: 162 - 339 Aligned: 164 Modelled: 178 Confidence: 98.7% Identity: 21% PDB header:hydrolase Chain: B: PDB Molecule:cutinase-like protein; PDBTitle: a novel cutinase-like protein from cryptococcus sp. Phyre2 PDB 1cex chain A Region: 161 - 286 Aligned: 117 Modelled: 126 Confidence: 98.6% Identity: 14% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 5x88 chain A Region: 161 - 295 Aligned: 124 Modelled: 133 Confidence: 98.6% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:cutinase; PDBTitle: a crystal structure of cutinases from malbranchea cinnamomea Phyre2 PDB 3dd5 chain F Region: 161 - 286 Aligned: 119 Modelled: 126 Confidence: 98.5% Identity: 12% PDB header:hydrolase Chain: F: PDB Molecule:cutinase; PDBTitle: glomerella cingulata e600-cutinase complex Phyre2 PDB 3gbs chain A Region: 161 - 283 Aligned: 114 Modelled: 123 Confidence: 98.3% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:cutinase 1; PDBTitle: crystal structure of aspergillus oryzae cutinase Phyre2 PDB 4oyl chain C Region: 161 - 286 Aligned: 118 Modelled: 126 Confidence: 98.3% Identity: 16% PDB header:hydrolase Chain: C: PDB Molecule:cutinase; PDBTitle: humicola insolens cutinase in complex with mono-ethylphosphate Phyre2 PDB 4psd chain A Region: 196 - 282 Aligned: 75 Modelled: 87 Confidence: 98.2% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:carbohydrate esterase family 5; PDBTitle: structure of trichoderma reesei cutinase native form. Phyre2 PDB 5xav chain B Region: 206 - 280 Aligned: 70 Modelled: 75 Confidence: 93.8% Identity: 13% PDB header:biosynthetic protein Chain: B: PDB Molecule:intracellular polyhydroxyalkanoate synthase; PDBTitle: structure of phac from chromobacterium sp. usm2 Phyre2 PDB 1jmk chain C Region: 205 - 285 Aligned: 70 Modelled: 81 Confidence: 92.9% Identity: 17% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Thioesterase domain of polypeptide, polyketide and fatty acid synthases Phyre2 PDB 2g38 chain B domain 1 Region: 47 - 134 Aligned: 86 Modelled: 88 Confidence: 92.8% Identity: 12% Fold: Ferritin-like Superfamily: PE/PPE dimer-like Family: PPE Phyre2 PDB 2g38 chain B Region: 47 - 134 Aligned: 86 Modelled: 88 Confidence: 92.8% Identity: 12% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:ppe family protein; PDBTitle: a pe/ppe protein complex from mycobacterium tuberculosis Phyre2 PDB 3icv chain A Region: 219 - 324 Aligned: 98 Modelled: 106 Confidence: 92.5% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:lipase b; PDBTitle: structural consequences of a circular permutation on lipase b from2 candida antartica Phyre2 PDB 5t6o chain A Region: 206 - 280 Aligned: 70 Modelled: 75 Confidence: 91.5% Identity: 13% PDB header:biosynthetic protein Chain: A: PDB Molecule:poly-beta-hydroxybuterate polymerase; PDBTitle: structure of the catalytic domain of the class i polyhydroxybutyrate2 synthase from cupriavidus necator Phyre2 1 c5xfsA_ 2 c2g38A_ 3 d2g38a1 4 c3ajaA_ 5 c3hc7A_ 6 d1qoza_ 7 d1g66a_ 8 c2czqB_ 9 d1cexa_ 10 c5x88A_ 11 c3dd5F_ 12 c3gbsA_ 13 c4oylC_ 14 c4psdA_ 15 c5xavB_ 16 d1jmkc_ 17 d2g38b1 18 c2g38B_ 19 c3icvA_ 20 c5t6oA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105