1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	C	R	P	P	S	R	N	R	S	A	H	T	A	R	N	T	R	P	C	S	L	K	S	R	R	F	T	V	R	F	H	Q	T	L	A	A	A	A	N	S	Y	A	D	A	E	A	A	I	A	S	T	R	Q	N	Q	L	A	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?						?		?																																?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	A	A	A	P	T	P	A	A	A	A	M	I	P	P	F	P	A	N	L	T	T	L	F	F	G	P	T	G	I	P	L	P	P	P	S	M	L	T	P	P	I	R	C	R	S	V	R	R	A	L	Q	A	V	F	T	P	E	E	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Y	P	L	T	G	V	R	S	L	V	L	N	T	S	V	E	E	G	L	T	I	L	H	D	A	I	M	V	E	L	A	T	T	G	N	A	V	T	V	F	G	W	S	Q	S	A	I	I	A	S	L	E	M	Q	R	F	T	A	M	G
Secondary structure
SS confidence
Disorder																																																													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	A	A	P	S	A	S	D	L	N	F	V	L	V	G	N	E	M	N	P	N	G	G	M	L	A	R	F	P	D	L	T	L	P	T	L	D	L	T	F	Y	G	A	T	P	S	D	T	I	Y	P	T	A	I	Y	T	L	E	Y	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?																																?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	F	A	D	F	S	R	Y	P	L	N	F	I	S	D	L	N	A	V	A	G	I	T	F	V	H	T	K	Y	L	D	L	T	P	A	Q	V	E	G	A	T	K	L	P	T	S	P	G	Y	T	G	V	T	D	Y	Y	I	I	R	T
Secondary structure
SS confidence
Disorder																																						?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		E	N	R	P	L	L	Q	P	L	R	A	V	P	V	I	G	D	P	L	A	D	L	I	Q	P	N	L	K	V	I	V	N	L	G	Y	G	D	P	N	Y	G	Y	S	T	S	Y	A	D	V	R	T	P	F	G	L	W	P	N	V	P
Secondary structure
SS confidence
Disorder												?																													?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		P	Q	V	I	A	D	A	L	A	A	G	T	Q	E	G	I	L	D	F	T	A	D	L	Q	A	L	S	A	Q	P	L	T	L	P	Q	I	Q	L	P	Q	P	A	D	L	V	A	A	V	A	A	A	P	T	P	A	E	V	V	N	T
Secondary structure
SS confidence
Disorder																								?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		L	A	R	I	I	S	T	N	Y	A	V	L	L	P	T	V	D	I	A	L	A	L	V	T	T	L	P	L	Y	T	T	Q	L	F	V	R	Q	L	A	A	G	N	L	I	N	A	I	G	Y	P	L	A	A	T	V	G	L	G	T	I
Secondary structure
SS confidence
Disorder				?	?		?	?	?	?					?		?	?	?		?																				?																				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.
Sequence		D	S	G	R	R	G	I	A	H	P	P	R	G	G	L	G	H	R	S	K	H	R	G	P	R	H	L	T	D	S	R	R	H	R	R	P	P	T	T	V	Y	R	P	R	Q
Secondary structure
SS confidence
Disorder			?	?	?							?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?			?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 27%) Alpha helix ( 38%) Beta strand ( 9%)

Rank Aligned region

PDB 3aja chain A Region: 75 - 273 Aligned: 199 Modelled: 199 Confidence: 99.9% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of msmeg_6394 Phyre2 PDB 1qoz chain A Region: 77 - 249 Aligned: 167 Modelled: 173 Confidence: 99.3% Identity: 16% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 3hc7 chain A Region: 78 - 247 Aligned: 160 Modelled: 170 Confidence: 99.3% Identity: 20% PDB header:cell adhesion Chain: A: PDB Molecule:gene 12 protein; PDBTitle: crystal structure of lysin b from mycobacteriophage d29 Phyre2 PDB 1g66 chain A Region: 76 - 207 Aligned: 130 Modelled: 132 Confidence: 99.3% Identity: 12% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 2czq chain B Region: 72 - 257 Aligned: 173 Modelled: 186 Confidence: 99.1% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:cutinase-like protein; PDBTitle: a novel cutinase-like protein from cryptococcus sp. Phyre2 PDB 3dd5 chain F Region: 72 - 212 Aligned: 132 Modelled: 141 Confidence: 99.0% Identity: 12% PDB header:hydrolase Chain: F: PDB Molecule:cutinase; PDBTitle: glomerella cingulata e600-cutinase complex Phyre2 PDB 1cex chain A Region: 74 - 203 Aligned: 121 Modelled: 130 Confidence: 99.0% Identity: 14% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 5x88 chain A Region: 75 - 212 Aligned: 127 Modelled: 136 Confidence: 98.9% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:cutinase; PDBTitle: a crystal structure of cutinases from malbranchea cinnamomea Phyre2 PDB 3gbs chain A Region: 77 - 202 Aligned: 119 Modelled: 126 Confidence: 98.8% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:cutinase 1; PDBTitle: crystal structure of aspergillus oryzae cutinase Phyre2 PDB 4psd chain A Region: 27 - 199 Aligned: 152 Modelled: 173 Confidence: 98.7% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:carbohydrate esterase family 5; PDBTitle: structure of trichoderma reesei cutinase native form. Phyre2 PDB 4oyl chain C Region: 71 - 203 Aligned: 125 Modelled: 133 Confidence: 98.6% Identity: 12% PDB header:hydrolase Chain: C: PDB Molecule:cutinase; PDBTitle: humicola insolens cutinase in complex with mono-ethylphosphate Phyre2 PDB 5xfs chain A Region: 15 - 40 Aligned: 26 Modelled: 26 Confidence: 97.5% Identity: 19% PDB header:protein transport Chain: A: PDB Molecule:pe family protein pe8; PDBTitle: crystal structure of pe8-ppe15 in complex with espg5 from m.2 tuberculosis Phyre2 PDB 2g38 chain A domain 1 Region: 15 - 40 Aligned: 26 Modelled: 26 Confidence: 97.5% Identity: 23% Fold: Ferritin-like Superfamily: PE/PPE dimer-like Family: PE Phyre2 PDB 2g38 chain A Region: 15 - 40 Aligned: 26 Modelled: 26 Confidence: 97.5% Identity: 23% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:pe family protein; PDBTitle: a pe/ppe protein complex from mycobacterium tuberculosis Phyre2 PDB 3icv chain A Region: 135 - 243 Aligned: 97 Modelled: 109 Confidence: 96.1% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:lipase b; PDBTitle: structural consequences of a circular permutation on lipase b from2 candida antartica Phyre2 PDB 1tca chain A Region: 134 - 199 Aligned: 61 Modelled: 66 Confidence: 94.6% Identity: 20% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Fungal lipases Phyre2 PDB 5xav chain B Region: 127 - 197 Aligned: 65 Modelled: 71 Confidence: 94.2% Identity: 14% PDB header:biosynthetic protein Chain: B: PDB Molecule:intracellular polyhydroxyalkanoate synthase; PDBTitle: structure of phac from chromobacterium sp. usm2 Phyre2 PDB 5t6o chain A Region: 127 - 197 Aligned: 65 Modelled: 67 Confidence: 94.2% Identity: 14% PDB header:biosynthetic protein Chain: A: PDB Molecule:poly-beta-hydroxybuterate polymerase; PDBTitle: structure of the catalytic domain of the class i polyhydroxybutyrate2 synthase from cupriavidus necator Phyre2 PDB 1jmk chain C Region: 121 - 202 Aligned: 70 Modelled: 82 Confidence: 93.9% Identity: 14% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Thioesterase domain of polypeptide, polyketide and fatty acid synthases Phyre2 PDB 1ei9 chain A Region: 85 - 204 Aligned: 109 Modelled: 120 Confidence: 92.3% Identity: 14% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Thioesterases Phyre2 1 c3ajaA_ 2 d1qoza_ 3 c3hc7A_ 4 d1g66a_ 5 c2czqB_ 6 c3dd5F_ 7 d1cexa_ 8 c5x88A_ 9 c3gbsA_ 10 c4psdA_ 11 c4oylC_ 12 c5xfsA_ 13 d2g38a1 14 c2g38A_ 15 c3icvA_ 16 d1tcaa_ 17 c5xavB_ 18 c5t6oA_ 19 d1jmkc_ 20 d1ei9a_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108