1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	A	T	V	E	I	R	R	A	A	D	R	A	V	T	T	T	S	W	L	K	S	R	H	S	F	S	F	G	D	H	Y	D	P	D	N	T	H	H	G	L	L	L	V	N	N	D	D	Q	M	E	P	A	S	G	F	D	P	H
Secondary structure
SS confidence
Disorder		?	?	?	?				?																																																			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	H	R	D	M	E	I	V	T	W	V	L	R	G	A	L	R	H	Q	D	S	A	G	N	S	G	V	I	Y	P	G	L	A	Q	R	M	S	A	G	T	G	I	L	H	S	E	M	N	D	S	A	T	E	P	V	H	F	V	Q	M
Secondary structure
SS confidence
Disorder																							?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		W	V	I	P	D	A	T	G	I	T	A	S	Y	Q	Q	Q	E	I	D	D	E	L	L	R	A	G	L	V	T	I	A	S	G	I	P	G	Q	D	A	A	L	T	L	H	N	S	S	A	S	L	H	G	A	R	L	R	P	G	A	T
Secondary structure
SS confidence
Disorder						?	?	?	?	?	?	?	?	?	?	?					?	?	?															?	?	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	S	L	P	C	A	P	F	L	H	L	F	V	A	Y	G	R	L	T	L	E	G	G	G	E	L	A	D	G	D	A	V	R	F	T	D	A	D	A	R	G	L	T	A	N	E	P	S	E	V	L	I	W	E	M	H	A	K	L	G
Secondary structure
SS confidence
Disorder																							?	?					?																														?	?	?
Disorder confidence
		.	.	.	.
Sequence		D	S	A	T
Secondary structure
SS confidence
Disorder		?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 15%) Alpha helix ( 3%) Beta strand ( 47%)

Rank Aligned region

PDB 1tq5 chain A domain 1 Region: 5 - 236 Aligned: 226 Modelled: 232 Confidence: 100.0% Identity: 35% Fold: Double-stranded beta-helix Superfamily: RmlC-like cupins Family: Pirin-like Phyre2 PDB 2vec chain A Region: 10 - 237 Aligned: 221 Modelled: 226 Confidence: 100.0% Identity: 25% PDB header:cytosolic protein Chain: A: PDB Molecule:pirin-like protein yhak; PDBTitle: the crystal structure of the protein yhak from escherichia2 coli Phyre2 PDB 6d0g chain A Region: 7 - 242 Aligned: 228 Modelled: 235 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:pirin family protein; PDBTitle: 1.78 angstrom resolution crystal structure of quercetin 2,3-2 dioxygenase from acinetobacter baumannii Phyre2 PDB 2p17 chain A Region: 40 - 242 Aligned: 198 Modelled: 203 Confidence: 100.0% Identity: 26% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:pirin-like protein; PDBTitle: crystal structure of gk1651 from geobacillus kaustophilus Phyre2 PDB 1j1l chain A Region: 35 - 242 Aligned: 205 Modelled: 208 Confidence: 100.0% Identity: 24% Fold: Double-stranded beta-helix Superfamily: RmlC-like cupins Family: Pirin-like Phyre2 PDB 6d0p chain C Region: 3 - 242 Aligned: 233 Modelled: 239 Confidence: 100.0% Identity: 23% PDB header:oxidoreductase Chain: C: PDB Molecule:pirin family protein; PDBTitle: 1.88 angstrom resolution crystal structure of quercetin 2,3-2 dioxygenase from acinetobacter baumannii Phyre2 PDB 4e2s chain E Region: 45 - 233 Aligned: 175 Modelled: 185 Confidence: 99.2% Identity: 15% PDB header:hydrolase Chain: E: PDB Molecule:ureidoglycine aminohydrolase; PDBTitle: crystal structure of (s)-ureidoglycine aminohydrolase from arabidopsis2 thaliana in complex with its substrate, (s)-ureidoglycine Phyre2 PDB 5zbf chain A Region: 50 - 235 Aligned: 170 Modelled: 174 Confidence: 98.9% Identity: 13% PDB header:isomerase Chain: A: PDB Molecule:cupin domain protein; PDBTitle: crystal structure of 4-hydroxyphenylpyruvic acid bound aere from2 microcystis aeruginosa Phyre2 PDB 3o14 chain B Region: 50 - 233 Aligned: 162 Modelled: 171 Confidence: 98.9% Identity: 24% PDB header:gene regulation Chain: B: PDB Molecule:anti-ecfsigma factor, chrr; PDBTitle: crystal structure of an anti-ecfsigma factor, chrr (maqu_0586) from2 marinobacter aquaeolei vt8 at 1.70 a resolution Phyre2 PDB 1sfn chain A Region: 50 - 233 Aligned: 174 Modelled: 182 Confidence: 98.9% Identity: 13% Fold: Double-stranded beta-helix Superfamily: RmlC-like cupins Family: YlbA-like Phyre2 PDB 1sq4 chain A Region: 39 - 233 Aligned: 179 Modelled: 186 Confidence: 98.9% Identity: 15% Fold: Double-stranded beta-helix Superfamily: RmlC-like cupins Family: YlbA-like Phyre2 PDB 1sef chain A Region: 39 - 233 Aligned: 179 Modelled: 192 Confidence: 98.9% Identity: 12% Fold: Double-stranded beta-helix Superfamily: RmlC-like cupins Family: YlbA-like Phyre2 PDB 1sef chain A Region: 39 - 233 Aligned: 179 Modelled: 192 Confidence: 98.9% Identity: 12% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of cupin domain protein ef2996 from enterococcus2 faecalis Phyre2 PDB 1rc6 chain A Region: 39 - 233 Aligned: 175 Modelled: 184 Confidence: 98.8% Identity: 13% Fold: Double-stranded beta-helix Superfamily: RmlC-like cupins Family: YlbA-like Phyre2 PDB 3h8u chain A Region: 27 - 132 Aligned: 102 Modelled: 106 Confidence: 98.6% Identity: 25% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized conserved protein with double-stranded PDBTitle: crystal structure of uncharacterized conserved protein with double-2 stranded beta-helix domain (yp_001338853.1) from klebsiella3 pneumoniae subsp. pneumoniae mgh 78578 at 1.80 a resolution Phyre2 PDB 3h7y chain A Region: 50 - 239 Aligned: 177 Modelled: 190 Confidence: 98.6% Identity: 12% PDB header:biosynthetic protein Chain: A: PDB Molecule:bacilysin biosynthesis protein bacb; PDBTitle: crystal structure of bacb, an enzyme involved in bacilysin synthesis,2 in tetragonal form Phyre2 PDB 2d40 chain C Region: 50 - 234 Aligned: 176 Modelled: 175 Confidence: 98.5% Identity: 14% PDB header:oxidoreductase Chain: C: PDB Molecule:putative gentisate 1,2-dioxygenase; PDBTitle: crystal structure of z3393 from escherichia coli o157:h7 Phyre2 PDB 2ozi chain A Region: 43 - 120 Aligned: 74 Modelled: 78 Confidence: 98.4% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein rpa4178; PDBTitle: structural genomics, the crystal structure of a putative2 protein rpa4178 from rhodopseudomonas palustris cga009 Phyre2 PDB 3rns chain A Region: 51 - 233 Aligned: 159 Modelled: 182 Confidence: 98.4% Identity: 11% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:cupin 2 conserved barrel domain protein; PDBTitle: cupin 2 conserved barrel domain protein from leptotrichia buccalis Phyre2 PDB 2vqa chain C Region: 50 - 242 Aligned: 190 Modelled: 181 Confidence: 98.4% Identity: 19% PDB header:metal-binding protein Chain: C: PDB Molecule:sll1358 protein; PDBTitle: protein-folding location can regulate mn versus cu- or zn-2 binding. crystal structure of mnca. Phyre2 1 d1tq5a1 2 c2vecA_ 3 c6d0gA_ 4 c2p17A_ 5 d1j1la_ 6 c6d0pC_ 7 c4e2sE_ 8 c5zbfA_ 9 c3o14B_ 10 d1sfna_ 11 d1sq4a_ 12 d1sefa_ 13 c1sefA_ 14 d1rc6a_ 15 c3h8uA_ 16 c3h7yA_ 17 c2d40C_ 18 c2oziA_ 19 c3rnsA_ 20 c2vqaC_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159