Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD0185_(-)_215713_216222
DateTue Jul 23 14:50:23 BST 2019
Unique Job ID4bfe98c69fa01379
SequenceVIGADVPRDS ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:34.780 Y:26.296 Z:29.071
Model (left) based on template c6mdxA_
Top template information
PDB header:dna binding protein/dna
Chain: A: PDB Molecule:sprt-like domain-containing protein spartan;
PDBTitle: mechanism of protease dependent dpc repair
Confidence and coverage
Confidence: 93.0% Coverage: 36%
61 residues ( 36% of your sequence) have been modelled with 93.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c6mdxA_



93.0 23
PDB header:dna binding protein/dna
Chain: A: PDB Molecule:sprt-like domain-containing protein spartan;
PDBTitle: mechanism of protease dependent dpc repair
2c5xbvA_



91.1 23
PDB header:hydrolase
Chain: A: PDB Molecule:wss1p;
PDBTitle: crystal structure of wss1 mutant from saccharomyces cerevisiae
3d2ejqa1



86.0 60
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:TTHA0227-like
4c4jiuA_



84.7 29
PDB header:hydrolase
Chain: A: PDB Molecule:proabylysin;
PDBTitle: crystal structure of the metallopeptidase zymogen of pyrococcus abyssi2 abylysin
5c4jixB_



80.3 25
PDB header:hydrolase
Chain: B: PDB Molecule:projannalysin;
PDBTitle: crystal structure of the metallopeptidase zymogen of2 methanocaldococcus jannaschii jannalysin
6d3e11a1



68.6 60
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:TTHA0227-like
7c5a0sA_



65.2 15
PDB header:hydrolase
Chain: A: PDB Molecule:zinc metalloprotease zmp1;
PDBTitle: apo-structure of metalloprotease zmp1 variant e143a from clostridium2 difficile
8c6fpcA_



63.1 11
PDB header:hydrolase
Chain: A: PDB Molecule:pro-pro endopeptidase;
PDBTitle: structure of the pro-pro endopeptidase (ppep-2) from paenibacillus2 alvei
9c2l0rA_



57.9 23
PDB header:hydrolase,toxin
Chain: A: PDB Molecule:lethal factor;
PDBTitle: conformational dynamics of the anthrax lethal factor catalytic center
10c3dl1A_



57.4 64
PDB header:hydrolase
Chain: A: PDB Molecule:putative metal-dependent hydrolase;
PDBTitle: crystal structure of a putative metal-dependent hydrolase2 (yp_001336084.1) from klebsiella pneumoniae subsp. pneumoniae mgh3 78578 at 2.20 a resolution
11c5ln5A_



46.5 22
PDB header:hydrolase
Chain: A: PDB Molecule:ubiquitin and wlm domain-containing metalloprotease
PDBTitle: crystal structure of the wss1 e203q mutant from s. pombe
12d1j7na2



35.0 27
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Anthrax toxin lethal factor, N- and C-terminal domains
13c3vtgA_



33.0 19
PDB header:hydrolase
Chain: A: PDB Molecule:high choriolytic enzyme 1;
PDBTitle: high choriolytic enzyme 1 (hce-1), a hatching enzyme zinc-protease2 from oryzias latipes (medaka fish)
14c2i47A_



32.1 24
PDB header:hydrolase
Chain: A: PDB Molecule:adam 17;
PDBTitle: crystal structure of catalytic domain of tace with inhibitor
15c3kf8D_



31.6 40
PDB header:structural protein
Chain: D: PDB Molecule:protein ten1;
PDBTitle: crystal structure of c. tropicalis stn1-ten1 complex
16c4igjB_



27.0 20
PDB header:isomerase
Chain: B: PDB Molecule:maleylacetoacetate isomerase;
PDBTitle: crystal structure of maleylacetoacetate isomerase from2 anaeromyxobacter dehalogenans 2cp-1, target efi-507175
17d1hfca_



24.6 38
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Matrix metalloproteases, catalytic domain
18d1eb6a_



24.4 24
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Fungal zinc peptidase
19d1asta_



24.2 16
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Astacin
20d1hv5a_



23.8 42
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Matrix metalloproteases, catalytic domain
21c5y7iB_



not modelled 23.5 23
PDB header:transport protein
Chain: B: PDB Molecule:chloride intracellular channel protein 2;
PDBTitle: structure of tilapia fish clic2
22d1rm8a_



not modelled 22.2 50
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Matrix metalloproteases, catalytic domain
23d1q3aa_



not modelled 22.1 46
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Matrix metalloproteases, catalytic domain
24d1hova_



not modelled 21.7 42
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Matrix metalloproteases, catalytic domain
25d1i76a_



not modelled 21.2 50
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Matrix metalloproteases, catalytic domain
26d1cxva_



not modelled 21.0 42
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Matrix metalloproteases, catalytic domain
27c6jwkB_



not modelled 20.9 24
PDB header:isomerase
Chain: B: PDB Molecule:probable glutathione s-transferase;
PDBTitle: crystal structure of maleylpyruvate isomerase from pseudomonas2 aeruginosa pao1
28c3b4rA_



not modelled 20.9 67
PDB header:hydrolase
Chain: A: PDB Molecule:putative zinc metalloprotease mj0392;
PDBTitle: site-2 protease from methanocaldococcus jannaschii
29d1cgla_



not modelled 20.1 42
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Matrix metalloproteases, catalytic domain
30c5dqsD_



not modelled 20.0 13
PDB header:translation
Chain: D: PDB Molecule:elongation factor 1-beta;
PDBTitle: complex structure of human elongation factor 1b alpha and gamma gst-2 like domains
31d1g12a_



not modelled 19.2 32
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Fungal zinc peptidase
32d1eaka2



not modelled 18.9 33
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Matrix metalloproteases, catalytic domain
33c3cqbB_



not modelled 18.9 60
PDB header:hydrolase
Chain: B: PDB Molecule:probable protease htpx homolog;
PDBTitle: crystal structure of heat shock protein htpx domain from vibrio2 parahaemolyticus rimd 2210633
34d1xuca1



not modelled 18.9 50
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Matrix metalloproteases, catalytic domain
35d1hy7a_



not modelled 17.5 50
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Matrix metalloproteases, catalytic domain
36d1bqqm_



not modelled 17.5 50
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Matrix metalloproteases, catalytic domain
37d2ovxa1



not modelled 17.4 42
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Matrix metalloproteases, catalytic domain
38c3t6gB_



not modelled 17.3 28
PDB header:signaling protein, cell adhesion
Chain: B: PDB Molecule:breast cancer anti-estrogen resistance protein 1;
PDBTitle: structure of the complex between nsp3 (shep1) and p130cas
39d1y93a1



not modelled 17.2 38
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Matrix metalloproteases, catalytic domain
40c3b4rB_



not modelled 17.1 67
PDB header:hydrolase
Chain: B: PDB Molecule:putative zinc metalloprotease mj0392;
PDBTitle: site-2 protease from methanocaldococcus jannaschii
41c3dtkA_



not modelled 17.0 16
PDB header:gene regulation
Chain: A: PDB Molecule:irre protein;
PDBTitle: crystal structure of the irre protein, a central regulator2 of dna damage repair in deinococcaceae
42d1fbla2



not modelled 17.0 38
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Matrix metalloproteases, catalytic domain
43d1smye_



not modelled 16.5 46
Fold:RPB6/omega subunit-like
Superfamily:RPB6/omega subunit-like
Family:RNA polymerase omega subunit
44d1g9ka2



not modelled 16.3 36
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain
45d1fw1a1



not modelled 14.9 20
Fold:GST C-terminal domain-like
Superfamily:GST C-terminal domain-like
Family:Glutathione S-transferase (GST), C-terminal domain
46c2xs4A_



not modelled 14.7 42
PDB header:hydrolase
Chain: A: PDB Molecule:karilysin protease;
PDBTitle: structure of karilysin catalytic mmp domain in complex with magnesium
47c5czwA_



not modelled 14.5 33
PDB header:hydrolase
Chain: A: PDB Molecule:myroilysin;
PDBTitle: crystal structure of myroilysin
48c3lqbA_



not modelled 14.5 15
PDB header:hydrolase
Chain: A: PDB Molecule:loc792177 protein;
PDBTitle: crystal structure of the hatching enzyme zhe1 from the zebrafish danio2 rerio
49d1qiba_



not modelled 14.3 42
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Matrix metalloproteases, catalytic domain
50c3edhA_



not modelled 14.1 40
PDB header:hydrolase
Chain: A: PDB Molecule:bone morphogenetic protein 1;
PDBTitle: crystal structure of bone morphogenetic protein 1 protease2 domain in complex with partially bound dmso
51c2v4jA_



not modelled 12.8 27
PDB header:oxidoreductase
Chain: A: PDB Molecule:sulfite reductase, dissimilatory-type subunit
PDBTitle: the crystal structure of desulfovibrio vulgaris2 dissimilatory sulfite reductase bound to dsrc provides3 novel insights into the mechanism of sulfate respiration
52c3lq0A_



not modelled 12.6 19
PDB header:hydrolase
Chain: A: PDB Molecule:proastacin;
PDBTitle: zymogen structure of crayfish astacin metallopeptidase
53d1ynjk1



not modelled 12.6 46
Fold:RPB6/omega subunit-like
Superfamily:RPB6/omega subunit-like
Family:RNA polymerase omega subunit
54d1mmqa_



not modelled 12.5 33
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Matrix metalloproteases, catalytic domain
55d1k7ia2



not modelled 12.3 36
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain
56c3touB_



not modelled 12.0 14
PDB header:transferase
Chain: B: PDB Molecule:glutathione s-transferase protein;
PDBTitle: crystal structure of glutathione transferase (target efi-501058) from2 ralstonia solanacearum gmi1000 with gsh bound
57d1dp7p_



not modelled 11.5 17
Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:P4 origin-binding domain-like
58d2i47a1



not modelled 11.4 24
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:TNF-alpha converting enzyme, TACE, catalytic domain
59d1sata2



not modelled 11.0 36
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain
60c4l7aB_



not modelled 11.0 47
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a putative zinc-binding metallo-peptidase2 (baccac_01431) from bacteroides caccae atcc 43185 at 2.10 a3 resolution
61c2jl4A_



not modelled 10.5 16
PDB header:isomerase
Chain: A: PDB Molecule:maleylpyruvate isomerase;
PDBTitle: holo structure of maleyl pyruvate isomerase, a bacterial2 glutathione-s-transferase in zeta class
62d2h7ca1



not modelled 10.3 50
Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Acetylcholinesterase-like
63d3c7ba2



not modelled 10.3 25
Fold:Ferredoxin-like
Superfamily:Nitrite/Sulfite reductase N-terminal domain-like
Family:DsrA/DsrB N-terminal-domain-like
64d1gz7a_



not modelled 10.3 33
Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Fungal lipases
65c2pm8A_



not modelled 10.2 50
PDB header:hydrolase
Chain: A: PDB Molecule:cholinesterase;
PDBTitle: crystal structure of recombinant full length human2 butyrylcholinesterase
66d1kapp2



not modelled 10.2 36
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain
67c1slmA_



not modelled 10.2 50
PDB header:hydrolase
Chain: A: PDB Molecule:stromelysin-1;
PDBTitle: crystal structure of fibroblast stromelysin-1: the c-truncated human2 proenzyme
68c2x3bB_



not modelled 10.1 27
PDB header:hydrolase
Chain: B: PDB Molecule:toxic extracellular endopeptidase;
PDBTitle: asap1 inactive mutant e294a, an extracellular toxic zinc2 metalloendopeptidase
69c4fg5B_



not modelled 10.1 29
PDB header:hydrolase
Chain: B: PDB Molecule:e3 alpha-esterase-7 caboxylesterase;
PDBTitle: crystal structure of the alpha-esterase-7 carboxylesterase, e3, from2 lucilia cuprina
70c2j83B_



not modelled 9.8 40
PDB header:hydrolase
Chain: B: PDB Molecule:ulilysin;
PDBTitle: ulilysin metalloprotease in complex with batimastat.
71c2jsdA_



not modelled 9.7 38
PDB header:hydrolase
Chain: A: PDB Molecule:matrix metalloproteinase-20;
PDBTitle: solution structure of mmp20 complexed with nngh
72c4pdnA_



not modelled 9.6 50
PDB header:oxidoreductase
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of e. coli yfcm
73c2gtqA_



not modelled 9.4 50
PDB header:hydrolase
Chain: A: PDB Molecule:aminopeptidase n;
PDBTitle: crystal structure of aminopeptidase n from human pathogen neisseria2 meningitidis
74c2qiyC_



not modelled 9.3 100
PDB header:signaling protein/hydrolase
Chain: C: PDB Molecule:ubiquitin carboxyl-terminal hydrolase 3;
PDBTitle: yeast deubiquitinase ubp3 and bre5 cofactor complex
75c2qiyD_



not modelled 9.3 100
PDB header:signaling protein/hydrolase
Chain: D: PDB Molecule:ubiquitin carboxyl-terminal hydrolase 3;
PDBTitle: yeast deubiquitinase ubp3 and bre5 cofactor complex
76c4ke3D_



not modelled 9.3 16
PDB header:transferase
Chain: D: PDB Molecule:glutathione s-transferase domain;
PDBTitle: crystal structure of a glutathione transferase family member from2 burkholderia graminis, target efi-507264, no gsh, disordered domains,3 space group p21, form(2)
77d2gpfa1



not modelled 9.2 21
Fold:MbtH/L9 domain-like
Superfamily:MbtH-like
Family:MbtH-like
78d1ukca_



not modelled 9.1 29
Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Fungal lipases
79c5x61A_



not modelled 9.1 50
PDB header:hydrolase
Chain: A: PDB Molecule:acetylcholinesterase;
PDBTitle: crystal structure of acetylcholinesterase catalytic subunit of the2 malaria vector anopheles gambiae, 3.4 a
80c6i2tC_



not modelled 8.9 50
PDB header:hydrolase
Chain: C: PDB Molecule:cholinesterase;
PDBTitle: cryoem reconstruction of full-length, fully-glycosylated human2 butyrylcholinesterase tetramer
81d2ha2a1



not modelled 8.8 38
Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Acetylcholinesterase-like
82c4bdtA_



not modelled 8.8 50
PDB header:hydrolase/inhibitor
Chain: A: PDB Molecule:acetylcholinesterase;
PDBTitle: human acetylcholinesterase in complex with huprine w and fasciculin 2
83c3c37B_



not modelled 8.8 22
PDB header:hydrolase
Chain: B: PDB Molecule:peptidase, m48 family;
PDBTitle: x-ray structure of the putative zn-dependent peptidase q74d82 at the2 resolution 1.7 a. northeast structural genomics consortium target3 gsr143a
84c1su3A_



not modelled 8.6 42
PDB header:hydrolase
Chain: A: PDB Molecule:interstitial collagenase;
PDBTitle: x-ray structure of human prommp-1: new insights into2 collagenase action
85c2mzeA_



not modelled 8.6 25
PDB header:hydrolase
Chain: A: PDB Molecule:matrilysin;
PDBTitle: nmr solution structure of the pro form of human matrilysin (prommp-7)
86c5a2gB_



not modelled 8.6 50
PDB header:hydrolase
Chain: B: PDB Molecule:carboxylic ester hydrolase;
PDBTitle: an esterase from anaerobic clostridium hathewayi can2 hydrolyze aliphatic aromatic polyesters
87c3k7lA_



not modelled 8.3 33
PDB header:hydrolase
Chain: A: PDB Molecule:atragin;
PDBTitle: structures of two elapid snake venom metalloproteases with2 distinct activities highlight the disulfide patterns in the3 d domain of adamalysin family proteins
88c6be6D_



not modelled 8.3 15
PDB header:membrane protein
Chain: D: PDB Molecule:disintegrin and metalloproteinase domain-containing protein
PDBTitle: adam10 extracellular domain
89c4gerB_



not modelled 8.3 33
PDB header:hydrolase
Chain: B: PDB Molecule:gentlyase metalloprotease;
PDBTitle: crystal structure of gentlyase, the neutral metalloprotease of2 paenibacillus polymyxa
90d1dx4a_



not modelled 8.2 24
Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Acetylcholinesterase-like
91c5w1uA_



not modelled 8.1 38
PDB header:hydrolase
Chain: A: PDB Molecule:carboxylic ester hydrolase;
PDBTitle: culex quinquefasciatus carboxylesterase b2
92c2xpyA_



not modelled 8.1 56
PDB header:hydrolase
Chain: A: PDB Molecule:leukotriene a-4 hydrolase;
PDBTitle: structure of native leukotriene a4 hydrolase from saccharomyces2 cerevisiae
93c2voiB_



not modelled 8.1 45
PDB header:apoptosis
Chain: B: PDB Molecule:bh3-interacting domain death agonist p13;
PDBTitle: structure of mouse a1 bound to the bid bh3-domain
94c5zi7A_



not modelled 7.9 42
PDB header:hydrolase
Chain: A: PDB Molecule:aminopeptidase n;
PDBTitle: crystal structure of legionella pneumophila aminopeptidase a in2 complex with glutamic acid
95d1npca_



not modelled 7.9 33
Fold:Zincin-like
Superfamily:Metalloproteases ("zincins"), catalytic domain
Family:Thermolysin-like
96c3biwD_



not modelled 7.8 29
PDB header:cell adhesion/cell adhesion
Chain: D: PDB Molecule:neuroligin-1;
PDBTitle: crystal structure of the neuroligin-1/neurexin-1beta synaptic adhesion2 complex
97d1llfa_



not modelled 7.8 29
Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Fungal lipases
98d2v4ja2



not modelled 7.7 25
Fold:Ferredoxin-like
Superfamily:Nitrite/Sulfite reductase N-terminal domain-like
Family:DsrA/DsrB N-terminal-domain-like
99c5dllA_



not modelled 7.7 45
PDB header:hydrolase
Chain: A: PDB Molecule:aminopeptidase n;
PDBTitle: aminopeptidase n (pepn) from francisella tularensis subsp. tularensis2 schu s4

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