1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	T	L	A	A	E	P	H	P	A	P	P	Q	Q	P	T	V	A	W	S	E	P	D	V	D	R	R	V	E	F	W	P	T	V	A	I	R	S	A	L	E	S	G	D	I	A	T	W	Q	R	I	A	A	A	L	K	R	D	P	Y
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	R	T	A	R	Q	V	E	E	V	L	E	G	I	P	A	T	G	I	A	N	A	F	W	E	V	L	D	R	A	R	T	H	L	D	A	N	E	R	A	E	V	A	R	Q	V	G	L	L	L	D	R	S	G	L	Q	R	Q	E	F
Secondary structure
SS confidence
Disorder		?	?	?													?																		?	?																		?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.
Sequence		A	S	R	I	G	V	T	A	Q	D	L	T	A	Y	L	D	G	I	V	S	P	S	A	S	L	M	I	R	M	R	R	L	S	D	R	F	V	R	A	K	S	V	R	A	A	D	S
Secondary structure
SS confidence
Disorder																			?	?			?																					?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 19%) Alpha helix ( 69%) Beta strand ( 0%)

Rank Aligned region

PDB 1y9q chain A Region: 95 - 152 Aligned: 58 Modelled: 55 Confidence: 95.8% Identity: 22% PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, hth_3 family; PDBTitle: crystal structure of hth_3 family transcriptional regulator2 from vibrio cholerae Phyre2 PDB 2xcj chain B Region: 102 - 149 Aligned: 48 Modelled: 48 Confidence: 95.3% Identity: 25% PDB header:viral protein Chain: B: PDB Molecule:c protein; PDBTitle: crystal structure of p2 c, the immunity repressor of2 temperate e. coli phage p2 Phyre2 PDB 3trb chain A Region: 109 - 152 Aligned: 44 Modelled: 44 Confidence: 94.5% Identity: 20% PDB header:dna binding protein Chain: A: PDB Molecule:virulence-associated protein i; PDBTitle: structure of an addiction module antidote protein of a higa (higa)2 family from coxiella burnetii Phyre2 PDB 3cec chain A Region: 102 - 152 Aligned: 51 Modelled: 51 Confidence: 94.4% Identity: 22% PDB header:transcription Chain: A: PDB Molecule:putative antidote protein of plasmid maintenance system; PDBTitle: crystal structure of a putative antidote protein of plasmid2 maintenance system (npun_f2943) from nostoc punctiforme pcc 73102 at3 1.60 a resolution Phyre2 PDB 4mcx chain E Region: 102 - 152 Aligned: 51 Modelled: 51 Confidence: 94.4% Identity: 27% PDB header:toxin Chain: E: PDB Molecule:antidote protein; PDBTitle: p. vulgaris higba structure, crystal form 2 Phyre2 PDB 6f8s chain A Region: 109 - 152 Aligned: 44 Modelled: 44 Confidence: 94.1% Identity: 18% PDB header:toxin Chain: A: PDB Molecule:xre family transcriptional regulator; PDBTitle: toxin-antitoxin complex grata Phyre2 PDB 1y9q chain A domain 1 Region: 95 - 152 Aligned: 58 Modelled: 55 Confidence: 94.0% Identity: 22% Fold: lambda repressor-like DNA-binding domains Superfamily: lambda repressor-like DNA-binding domains Family: Probable transcriptional regulator VC1968, N-terminal domain Phyre2 PDB 1x57 chain A domain 1 Region: 101 - 152 Aligned: 52 Modelled: 52 Confidence: 93.5% Identity: 21% Fold: lambda repressor-like DNA-binding domains Superfamily: lambda repressor-like DNA-binding domains Family: EDF1-like Phyre2 PDB 1adr chain A Region: 102 - 152 Aligned: 51 Modelled: 51 Confidence: 93.4% Identity: 6% Fold: lambda repressor-like DNA-binding domains Superfamily: lambda repressor-like DNA-binding domains Family: Phage repressors Phyre2 PDB 3vk0 chain B Region: 99 - 152 Aligned: 54 Modelled: 54 Confidence: 93.2% Identity: 20% PDB header:dna binding protein Chain: B: PDB Molecule:transcriptional regulator; PDBTitle: crystal structure of hypothetical transcription factor nhtf from2 neisseria Phyre2 PDB 3dnv chain B Region: 99 - 149 Aligned: 51 Modelled: 51 Confidence: 93.1% Identity: 14% PDB header:transcription/dna Chain: B: PDB Molecule:hth-type transcriptional regulator hipb; PDBTitle: mdt protein Phyre2 PDB 6b9r chain D Region: 95 - 152 Aligned: 58 Modelled: 58 Confidence: 93.1% Identity: 16% PDB header:oxidoreductase Chain: D: PDB Molecule:hydroxyethylphosphonate dioxygenase; PDBTitle: streptomyces albus hepd with substrate 2-hydroxyethylphosphonate (2-2 hep) and fe(ii) bound Phyre2 PDB 2o38 chain A Region: 92 - 149 Aligned: 58 Modelled: 55 Confidence: 93.0% Identity: 16% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: putative xre family transcriptional regulator Phyre2 PDB 2o38 chain A domain 1 Region: 92 - 149 Aligned: 58 Modelled: 55 Confidence: 93.0% Identity: 16% Fold: lambda repressor-like DNA-binding domains Superfamily: lambda repressor-like DNA-binding domains Family: NE1354 Phyre2 PDB 5j9i chain H Region: 103 - 152 Aligned: 50 Modelled: 50 Confidence: 92.9% Identity: 12% PDB header:antitoxin Chain: H: PDB Molecule:antitoxin iga-2; PDBTitle: crystal structure of the higa2 antitoxin c-terminal domain Phyre2 PDB 2jvl chain A Region: 101 - 152 Aligned: 52 Modelled: 52 Confidence: 92.8% Identity: 23% PDB header:transcription Chain: A: PDB Molecule:trmbf1; PDBTitle: nmr structure of the c-terminal domain of mbf1 of trichoderma reesei Phyre2 PDB 1rio chain A Region: 92 - 152 Aligned: 61 Modelled: 61 Confidence: 92.8% Identity: 15% Fold: lambda repressor-like DNA-binding domains Superfamily: lambda repressor-like DNA-binding domains Family: Phage repressors Phyre2 PDB 1y7y chain A domain 1 Region: 93 - 152 Aligned: 60 Modelled: 60 Confidence: 92.3% Identity: 13% Fold: lambda repressor-like DNA-binding domains Superfamily: lambda repressor-like DNA-binding domains Family: SinR domain-like Phyre2 PDB 2b5a chain A domain 1 Region: 99 - 152 Aligned: 54 Modelled: 54 Confidence: 92.3% Identity: 13% Fold: lambda repressor-like DNA-binding domains Superfamily: lambda repressor-like DNA-binding domains Family: SinR domain-like Phyre2 PDB 2kpj chain A Region: 97 - 152 Aligned: 56 Modelled: 56 Confidence: 92.3% Identity: 20% PDB header:transcription regulator Chain: A: PDB Molecule:sos-response transcriptional repressor, lexa; PDBTitle: solution structure of protein sos-response transcriptional2 repressor, lexa from eubacterium rectale. northeast3 structural genomics consortium target err9a Phyre2 1 c1y9qA_ 2 c2xcjB_ 3 c3trbA_ 4 c3cecA_ 5 c4mcxE_ 6 c6f8sA_ 7 d1y9qa1 8 d1x57a1 9 d1adra_ 10 c3vk0B_ 11 c3dnvB_ 12 c6b9rD_ 13 c2o38A_ 14 d2o38a1 15 c5j9iH_ 16 c2jvlA_ 17 d1rioa_ 18 d1y7ya1 19 d2b5aa1 20 c2kpjA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99