1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	D	P	A	R	G	A	E	A	E	D	A	Y	G	F	P	A	G	L	W	R	W	L	Q	R	H	P	P	P	A	L	H	R	L	T	R	F	R	S	P	L	R	G	P	W	L	T	S	V	F	G	L	V	L	L	V	A	L	P
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?												?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		F	V	I	I	T	G	L	L	S	Y	I	A	Y	A	P	Q	L	G	Q	A	I	P	G	D	V	G	W	L	R	L	P	A	F	T	W	P	T	R	P	S	W	L	Y	R	L	T	Q	G	L	H	V	G	L	G	L	V	I	I	P	V
Secondary structure
SS confidence
Disorder																			?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	L	A	K	L	W	S	V	I	P	R	L	F	V	W	P	P	A	R	S	I	A	Q	V	L	E	R	L	S	V	L	M	L	V	G	G	I	L	F	Q	I	V	T	G	V	L	N	I	Q	Y	D	Y	I	F	G	F	S	F	Y	T
Secondary structure
SS confidence
Disorder																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	H	Y	F	G	A	W	V	F	I	A	G	F	L	L	H	I	V	V	K	I	P	H	M	V	T	G	L	R	S	I	P	M	R	E	V	L	G	T	N	V	A	D	T	R	A	Q	P	C	D	P	D	G	L	V	S	V	N	P	G
Secondary structure
SS confidence
Disorder																																				?			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		E	A	T	L	S	R	R	G	A	L	G	L	V	G	A	G	V	L	L	I	G	V	L	T	V	G	Q	T	L	G	G	F	T	R	K	A	A	L	L	L	P	R	G	R	V	V	S	P	G	D	F	P	V	N	K	T	A	A	A	A
Secondary structure
SS confidence
Disorder		?																						?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	I	T	A	E	A	I	G	P	D	W	R	L	V	L	C	G	G	P	A	E	V	V	L	D	R	A	T	L	A	G	L	P	Q	R	T	A	R	L	P	L	A	C	V	E	G	W	S	A	V	R	T	W	S	G	V	P	L	A	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		L	A	L	L	A	G	V	P	A	A	R	S	A	R	V	T	S	L	Q	R	G	G	A	F	G	E	A	K	L	A	A	N	Q	I	A	D	P	D	A	L	L	A	L	R	V	D	G	A	D	L	S	L	D	H	G	Y	P	A	R	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.
Sequence		I	V	P	A	L	P	G	V	H	N	T	K	W	V	A	G	I	E	F	H	K	R
Secondary structure
SS confidence
Disorder																						?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 20%) Alpha helix ( 38%) Beta strand ( 15%) TM helix ( 26%) (View membrane topology prediction)

Rank Aligned region

PDB 1xdy chain A Region: 291 - 442 Aligned: 148 Modelled: 152 Confidence: 100.0% Identity: 28% Fold: Oxidoreductase molybdopterin-binding domain Superfamily: Oxidoreductase molybdopterin-binding domain Family: Oxidoreductase molybdopterin-binding domain Phyre2 PDB 1xdy chain C Region: 291 - 442 Aligned: 148 Modelled: 152 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: C: PDB Molecule:bacterial sulfite oxidase; PDBTitle: structural and biochemical identification of a novel2 bacterial oxidoreductase, w-containing cofactor Phyre2 PDB 2xts chain C Region: 282 - 442 Aligned: 155 Modelled: 161 Confidence: 100.0% Identity: 25% PDB header:oxidoreductase/electron transport Chain: C: PDB Molecule:sulfite dehydrogenase; PDBTitle: crystal structure of the sulfane dehydrogenase soxcd from paracoccus2 pantotrophus Phyre2 PDB 1sox chain B Region: 279 - 442 Aligned: 160 Modelled: 164 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: B: PDB Molecule:sulfite oxidase; PDBTitle: sulfite oxidase from chicken liver Phyre2 PDB 2bpb chain A Region: 300 - 442 Aligned: 141 Modelled: 143 Confidence: 100.0% Identity: 29% PDB header:oxidoreductase Chain: A: PDB Molecule:sulfite\:cytochrome c oxidoreductase subunit a; PDBTitle: sulfite dehydrogenase from starkeya novella Phyre2 PDB 2bih chain A Region: 275 - 442 Aligned: 161 Modelled: 168 Confidence: 100.0% Identity: 20% PDB header:oxidoreductase Chain: A: PDB Molecule:nitrate reductase [nadph]; PDBTitle: crystal structure of the molybdenum-containing nitrate2 reducing fragment of pichia angusta assimilatory nitrate3 reductase Phyre2 PDB 1ogp chain D Region: 282 - 442 Aligned: 157 Modelled: 161 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: D: PDB Molecule:sulfite oxidase; PDBTitle: the crystal structure of plant sulfite oxidase provides2 insight into sulfite oxidation in plants and animals Phyre2 PDB 1ogp chain A domain 2 Region: 282 - 442 Aligned: 157 Modelled: 161 Confidence: 100.0% Identity: 27% Fold: Oxidoreductase molybdopterin-binding domain Superfamily: Oxidoreductase molybdopterin-binding domain Family: Oxidoreductase molybdopterin-binding domain Phyre2 PDB 2a9d chain B Region: 279 - 442 Aligned: 160 Modelled: 164 Confidence: 100.0% Identity: 26% PDB header:oxidoreductase Chain: B: PDB Molecule:sulfite oxidase; PDBTitle: crystal structure of recombinant chicken sulfite oxidase with arg at2 residue 161 Phyre2 PDB 2bii chain A Region: 275 - 442 Aligned: 161 Modelled: 168 Confidence: 100.0% Identity: 20% PDB header:oxidoreductase Chain: A: PDB Molecule:nitrate reductase [nadph]; PDBTitle: crystal structure of nitrate-reducing fragment of2 assimilatory nitrate reductase from pichia angusta Phyre2 PDB 2a9d chain A domain 2 Region: 279 - 442 Aligned: 158 Modelled: 164 Confidence: 100.0% Identity: 27% Fold: Oxidoreductase molybdopterin-binding domain Superfamily: Oxidoreductase molybdopterin-binding domain Family: Oxidoreductase molybdopterin-binding domain Phyre2 PDB 4pw3 chain B Region: 279 - 442 Aligned: 161 Modelled: 164 Confidence: 100.0% Identity: 26% PDB header:oxidoreductase Chain: B: PDB Molecule:putative sulfite oxidase; PDBTitle: crystal structure of the sulfite dehydrogenase sort from sinorhizobium2 meliloti Phyre2 PDB 1kqf chain C Region: 47 - 216 Aligned: 152 Modelled: 152 Confidence: 98.4% Identity: 15% Fold: Heme-binding four-helical bundle Superfamily: Transmembrane di-heme cytochromes Family: Formate dehydrogenase N, cytochrome (gamma) subunit Phyre2 PDB 4gd3 chain A Region: 38 - 201 Aligned: 139 Modelled: 146 Confidence: 97.9% Identity: 21% PDB header:oxidoreductase/electron transport Chain: A: PDB Molecule:ni/fe-hydrogenase 1 b-type cytochrome subunit; PDBTitle: structure of e. coli hydrogenase-1 in complex with cytochrome b Phyre2 PDB 4gd3 chain B Region: 38 - 201 Aligned: 139 Modelled: 146 Confidence: 97.9% Identity: 21% PDB header:oxidoreductase/electron transport Chain: B: PDB Molecule:ni/fe-hydrogenase 1 b-type cytochrome subunit; PDBTitle: structure of e. coli hydrogenase-1 in complex with cytochrome b Phyre2 PDB 5oc0 chain A Region: 35 - 201 Aligned: 135 Modelled: 145 Confidence: 96.9% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome b561; PDBTitle: structure of e. coli superoxide oxidase Phyre2 PDB 6hwh chain B Region: 51 - 199 Aligned: 129 Modelled: 149 Confidence: 95.0% Identity: 20% PDB header:electron transport Chain: B: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur subunit; PDBTitle: structure of a functional obligate respiratory supercomplex from2 mycobacterium smegmatis Phyre2 PDB 2qjk chain M Region: 51 - 199 Aligned: 129 Modelled: 149 Confidence: 94.5% Identity: 20% PDB header:electron transport Chain: M: PDB Molecule:cytochrome b; PDBTitle: crystal structure analysis of mutant rhodobacter2 sphaeroides bc1 with stigmatellin and antimycin Phyre2 PDB 1q90 chain B Region: 51 - 199 Aligned: 129 Modelled: 146 Confidence: 92.9% Identity: 19% Fold: Heme-binding four-helical bundle Superfamily: Transmembrane di-heme cytochromes Family: Cytochrome b of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) Phyre2 PDB 2e74 chain A domain 1 Region: 51 - 199 Aligned: 129 Modelled: 143 Confidence: 91.7% Identity: 19% Fold: Heme-binding four-helical bundle Superfamily: Transmembrane di-heme cytochromes Family: Cytochrome b of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) Phyre2 1 d1xdya_ 2 c1xdyC_ 3 c2xtsC_ 4 c1soxB_ 5 c2bpbA_ 6 c2bihA_ 7 c1ogpD_ 8 d1ogpa2 9 c2a9dB_ 10 c2biiA_ 11 d2a9da2 12 c4pw3B_ 13 d1kqfc_ 14 c4gd3A_ 15 c4gd3B_ 16 c5oc0A_ 17 c6hwhb_ 18 c2qjkM_ 19 d1q90b_ 20 d2e74a1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67