1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	R	T	Q	V	Q	L	P	D	E	L	Y	R	D	A	K	R	V	A	H	E	H	E	M	T	L	A	E	V	V	R	R	G	L	E	H	M	V	R	I	Y	P	R	R	D	A	A	S	D	T	W	Q	P	P	T	P	R	R	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																					?		?	?	?	?	?							?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.
Sequence		G	P	F	R	A	S	E	E	T	W	R	E	L	A	N	E	A
Secondary structure
SS confidence
Disorder		?														?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 27%) Alpha helix ( 53%) Beta strand ( 0%)

Rank Aligned region

PDB 2k5j chain B Region: 1 - 60 Aligned: 60 Modelled: 60 Confidence: 97.1% Identity: 15% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein yiif; PDBTitle: solution structure of protein yiif from shigella flexneri2 serotype 5b (strain 8401) . northeast structural genomics3 consortium target sft1 Phyre2 PDB 5x3t chain A Region: 3 - 39 Aligned: 37 Modelled: 37 Confidence: 93.4% Identity: 38% PDB header:antitoxin/toxin Chain: A: PDB Molecule:antitoxin vapb26; PDBTitle: vapbc from mycobacterium tuberculosis Phyre2 PDB 2bj7 chain A domain 1 Region: 1 - 42 Aligned: 42 Modelled: 42 Confidence: 84.3% Identity: 17% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: CopG-like Phyre2 PDB 2bj3 chain D Region: 1 - 49 Aligned: 49 Modelled: 49 Confidence: 82.7% Identity: 14% PDB header:transcription Chain: D: PDB Molecule:nickel responsive regulator; PDBTitle: nikr-apo Phyre2 PDB 4me7 chain E Region: 2 - 40 Aligned: 39 Modelled: 36 Confidence: 79.4% Identity: 18% PDB header:hydrolase/hydrolase inhibitor Chain: E: PDB Molecule:antitoxin endoai; PDBTitle: crystal structure of bacillus subtilis toxin mazf in complex with2 cognate antitoxin maze Phyre2 PDB 2ca9 chain B Region: 1 - 42 Aligned: 42 Modelled: 42 Confidence: 77.5% Identity: 19% PDB header:transcription Chain: B: PDB Molecule:putative nickel-responsive regulator; PDBTitle: apo-nikr from helicobacter pylori in closed trans-2 conformation Phyre2 PDB 2rbf chain B Region: 2 - 41 Aligned: 40 Modelled: 40 Confidence: 64.6% Identity: 15% PDB header:oxidoreductase/dna Chain: B: PDB Molecule:bifunctional protein puta; PDBTitle: structure of the ribbon-helix-helix domain of escherichia coli puta2 (puta52) complexed with operator dna (o2) Phyre2 PDB 1q5v chain B Region: 1 - 49 Aligned: 49 Modelled: 49 Confidence: 64.3% Identity: 16% PDB header:transcription Chain: B: PDB Molecule:nickel responsive regulator; PDBTitle: apo-nikr Phyre2 PDB 6iya chain D Region: 4 - 47 Aligned: 44 Modelled: 44 Confidence: 46.4% Identity: 16% PDB header:antitoxin Chain: D: PDB Molecule:transcriptional regulator copg family; PDBTitle: structure of the dna binding domain of antitoxin copaso Phyre2 PDB 1wge chain A domain 1 Region: 46 - 72 Aligned: 26 Modelled: 27 Confidence: 39.6% Identity: 27% Fold: Rubredoxin-like Superfamily: CSL zinc finger Family: CSL zinc finger Phyre2 PDB 3obc chain B Region: 18 - 44 Aligned: 27 Modelled: 27 Confidence: 34.0% Identity: 30% PDB header:hydrolase Chain: B: PDB Molecule:pyrophosphatase; PDBTitle: crystal structure of a pyrophosphatase (af1178) from archaeoglobus2 fulgidus at 1.80 a resolution Phyre2 PDB 6bwq chain B Region: 13 - 33 Aligned: 21 Modelled: 21 Confidence: 33.3% Identity: 19% PDB header:metal binding protein Chain: B: PDB Molecule:pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel PDBTitle: larc2, the c-terminal domain of a cyclometallase involved in the2 synthesis of the npn cofactor of lactate racemase, in complex with3 mnctp Phyre2 PDB 2k29 chain A Region: 1 - 40 Aligned: 40 Modelled: 40 Confidence: 30.3% Identity: 23% PDB header:transcription Chain: A: PDB Molecule:antitoxin relb; PDBTitle: structure of the dbd domain of e. coli antitoxin relb Phyre2 PDB 2a3q chain A domain 1 Region: 18 - 43 Aligned: 26 Modelled: 26 Confidence: 29.5% Identity: 19% Fold: all-alpha NTP pyrophosphatases Superfamily: all-alpha NTP pyrophosphatases Family: MazG-like Phyre2 PDB 2q4p chain A Region: 18 - 43 Aligned: 26 Modelled: 26 Confidence: 29.5% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:protein rs21-c6; PDBTitle: ensemble refinement of the crystal structure of protein from mus2 musculus mm.29898 Phyre2 PDB 5ceg chain C Region: 1 - 41 Aligned: 41 Modelled: 41 Confidence: 29.4% Identity: 15% PDB header:toxin Chain: C: PDB Molecule:addiction module antidote protein, copg/arc/metj family; PDBTitle: x-ray structure of toxin/anti-toxin complex from mesorhizobium2 opportunistum Phyre2 PDB 1yws chain A domain 1 Region: 46 - 72 Aligned: 26 Modelled: 27 Confidence: 26.6% Identity: 15% Fold: Rubredoxin-like Superfamily: CSL zinc finger Family: CSL zinc finger Phyre2 PDB 2lkm chain A Region: 4 - 12 Aligned: 9 Modelled: 9 Confidence: 23.2% Identity: 78% PDB header:transcription Chain: A: PDB Molecule:phd finger protein 12; PDBTitle: structural basis for molecular interactions involving mrg domains:2 implications in chromatin biology Phyre2 PDB 2mqk chain A Region: 11 - 33 Aligned: 23 Modelled: 23 Confidence: 21.9% Identity: 9% PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent target dna activator b; PDBTitle: solution structure of n terminal domain of the mub aaa+ atpase Phyre2 PDB 2l9s chain A Region: 4 - 12 Aligned: 9 Modelled: 9 Confidence: 19.4% Identity: 78% PDB header:transcription Chain: A: PDB Molecule:phd finger protein 12; PDBTitle: solution structure of pf1 sid1-msin3a pah2 complex Phyre2 1 c2k5jB_ 2 c5x3tA_ 3 d2bj7a1 4 c2bj3D_ 5 c4me7E_ 6 c2ca9B_ 7 c2rbfB_ 8 c1q5vB_ 9 c6iyaD_ 10 d1wgea1 11 c3obcB_ 12 c6bwqB_ 13 c2k29A_ 14 d2a3qa1 15 c2q4pA_ 16 c5cegC_ 17 d1ywsa1 18 c2lkmA_ 19 c2mqkA_ 20 c2l9sA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69