Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD0305c_(PPE6)_372820_375711
DateTue Jul 23 14:50:37 BST 2019
Unique Job IDdf27703136929600
SequenceMDFVVSAPEV ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:62.320 Y:71.054 Z:70.103
Model (left) based on template c5xfsB_
Top template information
PDB header:protein transport
Chain: B: PDB Molecule:ppe family protein ppe15;
PDBTitle: crystal structure of pe8-ppe15 in complex with espg5 from m.2 tuberculosis
Confidence and coverage
Confidence:100.0% Coverage: 18%
173 residues ( 18% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
Warning: 63% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

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Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c5xfsB_



100.0 52
PDB header:protein transport
Chain: B: PDB Molecule:ppe family protein ppe15;
PDBTitle: crystal structure of pe8-ppe15 in complex with espg5 from m.2 tuberculosis
2d2g38b1



100.0 32
Fold:Ferritin-like
Superfamily:PE/PPE dimer-like
Family:PPE
3c2g38B_



100.0 32
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:ppe family protein;
PDBTitle: a pe/ppe protein complex from mycobacterium tuberculosis
4c4xy3A_



100.0 16
PDB header:protein transport
Chain: A: PDB Molecule:esx-1 secretion-associated protein espb;
PDBTitle: structure of esx-1 secreted protein espb
5c4wj2A_



97.8 18
PDB header:unknown function
Chain: A: PDB Molecule:antigen mtb48;
PDBTitle: mycobacterial protein
6c2vs0B_



97.1 13
PDB header:cell invasion
Chain: B: PDB Molecule:virulence factor esxa;
PDBTitle: structural analysis of homodimeric staphylococcal aureus2 virulence factor esxa
7c4iogD_



96.9 10
PDB header:unknown function
Chain: D: PDB Molecule:secreted protein esxb;
PDBTitle: the crystal structure of a secreted protein esxb (wild-type, in p212 space group) from bacillus anthracis str. sterne
8c3gvmA_



96.7 8
PDB header:viral protein
Chain: A: PDB Molecule:putative uncharacterized protein sag1039;
PDBTitle: structure of the homodimeric wxg-100 family protein from streptococcus2 agalactiae
9c3zbhC_



96.6 9
PDB header:unknown function
Chain: C: PDB Molecule:esxa;
PDBTitle: geobacillus thermodenitrificans esxa crystal form i
10d1wa8a1



95.7 18
Fold:Ferritin-like
Superfamily:EsxAB dimer-like
Family:ESAT-6 like
11d1wa8b1



86.7 18
Fold:Ferritin-like
Superfamily:EsxAB dimer-like
Family:ESAT-6 like
12c4lwsA_



86.5 15
PDB header:unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata
13c4lwsB_



84.9 16
PDB header:unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: esxa : esxb (semet) hetero-dimer from thermomonospora curvata
14d1ui5a2



80.6 24
Fold:Tetracyclin repressor-like, C-terminal domain
Superfamily:Tetracyclin repressor-like, C-terminal domain
Family:Tetracyclin repressor-like, C-terminal domain
15c4i0xA_



77.1 24
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:esat-6-like protein mab_3112;
PDBTitle: crystal structure of the mycobacterum abscessus esxef (mab_3112-2 mab_3113) complex
16c2kg7B_



73.9 15
PDB header:unknown function
Chain: B: PDB Molecule:esat-6-like protein esxh;
PDBTitle: structure and features of the complex formed by the tuberculosis2 virulence factors rv0287 and rv0288
17c3jywF_



72.6 41
PDB header:ribosome
Chain: F: PDB Molecule:60s ribosomal protein l7(a);
PDBTitle: structure of the 60s proteins for eukaryotic ribosome based on cryo-em2 map of thermomyces lanuginosus ribosome at 8.9a resolution
18c4i0xJ_



72.0 22
PDB header:structural genomics, unknown function
Chain: J: PDB Molecule:esat-6-like protein mab_3113;
PDBTitle: crystal structure of the mycobacterum abscessus esxef (mab_3112-2 mab_3113) complex
19c4yshA_



53.2 10
PDB header:oxidoreductase
Chain: A: PDB Molecule:glycine oxidase;
PDBTitle: crystal structure of glycine oxidase from geobacillus kaustophilus
20c4kvjA_



53.1 13
PDB header:oxidoreductase
Chain: A: PDB Molecule:fatty acid alpha-oxidase;
PDBTitle: crystal structure of oryza sativa fatty acid alpha-dioxygenase with2 hydrogen peroxide
21c2kg7A_



not modelled 52.0 38
PDB header:unknown function
Chain: A: PDB Molecule:uncharacterized protein esxg (pe family protein);
PDBTitle: structure and features of the complex formed by the tuberculosis2 virulence factors rv0287 and rv0288
22c3h6pB_



not modelled 45.0 35
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:esat-6 like protein esxs;
PDBTitle: crystal structure of rv3019c-rv3020c from mycobacterium tuberculosis
23c6ml3A_



not modelled 43.8 17
PDB header:transcription/dna
Chain: A: PDB Molecule:zinc finger and btb domain-containing protein 24;
PDBTitle: zbtb24 zinc fingers 4-8 with 19+1mer dna oligonucleotide (sequence 2)
24c5jydA_



not modelled 41.4 36
PDB header:oxidoreductase
Chain: A: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a putative short chain dehydrogenase from2 burkholderia cenocepacia
25d1p4ea2



not modelled 40.6 31
Fold:DNA breaking-rejoining enzymes
Superfamily:DNA breaking-rejoining enzymes
Family:Lambda integrase-like, catalytic core
26c4hhsA_



not modelled 38.9 13
PDB header:oxidoreductase
Chain: A: PDB Molecule:alpha-dioxygenase;
PDBTitle: crystal structure of fatty acid alpha-dioxygenase (arabidopsis2 thaliana)
27c2mdwA_



not modelled 37.8 43
PDB header:de novo protein
Chain: A: PDB Molecule:designed protein;
PDBTitle: nmr structure of a strand-swapped dimer of the ww domain
28c5xqgC_



not modelled 37.8 22
PDB header:lyase
Chain: C: PDB Molecule:pcrglx protein;
PDBTitle: crystal structure of a pl 26 exo-rhamnogalacturonan lyase from2 penicillium chrysogenum complexed with unsaturated galacturonosyl3 rhamnose
29c4egcA_



not modelled 37.5 31
PDB header:transcription/hydrolase
Chain: A: PDB Molecule:maltose-binding periplasmic protein, homeobox protein six1
PDBTitle: crystal structure of mbp-fused human six1 bound to human eya2 eya2 domain
30c5nxhB_



not modelled 35.4 12
PDB header:viral protein
Chain: B: PDB Molecule:long-tail fiber proximal subunit;
PDBTitle: crystal structure of the carboxy-terminal region of the bacteriophage2 t4 proximal long tail fibre protein gp34, residues 744-1289 at 2.93 angstrom resolution
31c3we7A_



not modelled 35.2 16
PDB header:hydrolase
Chain: A: PDB Molecule:putative uncharacterized protein ph0499;
PDBTitle: crystal structure of diacetylchitobiose deacetylase from pyrococcus2 horikoshii
32c2wa1A_



not modelled 35.1 24
PDB header:transferase
Chain: A: PDB Molecule:non-structural protein 5;
PDBTitle: structure of the methyltransferase domain from modoc virus,2 a flavivirus with no known vector (nkv)
33c3lx6B_



not modelled 34.2 11
PDB header:transferase
Chain: B: PDB Molecule:cytosine-specific methyltransferase;
PDBTitle: crystal structure of putative dna cytosine methylase from shigella2 flexneri 2a str. 2457t
34c2vsnB_



not modelled 32.6 16
PDB header:transferase
Chain: B: PDB Molecule:xcogt;
PDBTitle: structure and topological arrangement of an o-glcnac2 transferase homolog: insight into molecular control of3 intracellular glycosylation
35d2pgga1



not modelled 32.5 23
Fold:DNA/RNA polymerases
Superfamily:DNA/RNA polymerases
Family:RNA-dependent RNA-polymerase
36c1p4eB_



not modelled 32.2 31
PDB header:dna binding protein/recombination/dna
Chain: B: PDB Molecule:recombinase flp protein;
PDBTitle: flpe w330f mutant-dna holliday junction complex
37c2l2rA_



not modelled 31.9 41
PDB header:antimicrobial protein
Chain: A: PDB Molecule:antimicrobial peptide ecamp1;
PDBTitle: helical hairpin structure of a novel antimicrobial peptide ecamp1 from2 seeds of barnyard grass (echinochloa crus-galli)
38c4drbC_



not modelled 31.5 17
PDB header:dna binding protein/protein binding
Chain: C: PDB Molecule:fanconi anemia group m protein;
PDBTitle: the crystal structure of fancm bound mhf complex
39c5a99A_



not modelled 31.2 23
PDB header:viral protein
Chain: A: PDB Molecule:polyhedrin;
PDBTitle: crystal structure of operophtera brumata cpv19 polyhedra
40c1hn3A_



not modelled 30.9 46
PDB header:antitumor protein
Chain: A: PDB Molecule:p19 arf protein;
PDBTitle: solution structure of the n-terminal 37 amino acids of the2 mouse arf tumor suppressor protein
41c3vhxF_



not modelled 28.5 21
PDB header:cell cycle/signaling protein
Chain: F: PDB Molecule:kinesin-like protein kif23;
PDBTitle: the crystal structure of arf6-mklp1 (mitotic kinesin-like protein 1)2 complex
42c2ixdB_



not modelled 27.1 10
PDB header:hydrolase
Chain: B: PDB Molecule:lmbe-related protein;
PDBTitle: crystal structure of the putative deacetylase bc1534 from bacillus2 cereus
43c2fjaC_



not modelled 27.0 22
PDB header:oxidoreductase
Chain: C: PDB Molecule:adenylylsulfate reductase, subunit a;
PDBTitle: adenosine 5'-phosphosulfate reductase in complex with substrate
44c3gyxA_



not modelled 26.9 19
PDB header:oxidoreductase
Chain: A: PDB Molecule:adenylylsulfate reductase;
PDBTitle: crystal structure of adenylylsulfate reductase from2 desulfovibrio gigas
45c5yh0G_



not modelled 26.7 19
PDB header:transferase
Chain: G: PDB Molecule:drfam20c1;
PDBTitle: the structure of drfam20c1
46c1ddxA_



not modelled 26.0 26
PDB header:oxidoreductase
Chain: A: PDB Molecule:protein (prostaglandin h2 synthase-2);
PDBTitle: crystal structure of a mixture of arachidonic acid and prostaglandin2 bound to the cyclooxygenase active site of cox-2: prostaglandin3 structure
47c3pghD_



not modelled 25.6 23
PDB header:oxidoreductase
Chain: D: PDB Molecule:cyclooxygenase-2;
PDBTitle: cyclooxygenase-2 (prostaglandin synthase-2) complexed with a non-2 selective inhibitor, flurbiprofen
48c2gjmA_



not modelled 25.5 13
PDB header:oxidoreductase
Chain: A: PDB Molecule:lactoperoxidase;
PDBTitle: crystal structure of buffalo lactoperoxidase at 2.75a resolution
49d1uila_



not modelled 25.4 24
Fold:dsRBD-like
Superfamily:dsRNA-binding domain-like
Family:Double-stranded RNA-binding domain (dsRBD)
50c6qfbB_



not modelled 24.6 45
PDB header:lyase
Chain: B: PDB Molecule:atp-citrate synthase;
PDBTitle: structure of the human atp citrate lyase holoenzyme in complex with2 citrate, coenzyme a and mg.adp
51d1cvua1



not modelled 23.9 23
Fold:Heme-dependent peroxidases
Superfamily:Heme-dependent peroxidases
Family:Myeloperoxidase-like
52d1jnra1



not modelled 23.5 22
Fold:Spectrin repeat-like
Superfamily:Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
Family:Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
53c6e93A_



not modelled 23.2 14
PDB header:dna binding protein/dna
Chain: A: PDB Molecule:zinc finger and btb domain-containing protein 38;
PDBTitle: crystal structure of zbtb38 c-terminal zinc fingers 6-9 in complex2 with methylated dna
54c1bkvA_



not modelled 22.5 38
PDB header:structural protein
Chain: A: PDB Molecule:t3-785;
PDBTitle: collagen
55c2oyuP_



not modelled 22.4 18
PDB header:oxidoreductase
Chain: P: PDB Molecule:prostaglandin g/h synthase 1;
PDBTitle: indomethacin-(s)-alpha-ethyl-ethanolamide bound to cyclooxygenase-1
56d1c25a_



not modelled 22.1 24
Fold:Rhodanese/Cell cycle control phosphatase
Superfamily:Rhodanese/Cell cycle control phosphatase
Family:Cell cycle control phosphatase, catalytic domain
57c5lc5F_



not modelled 21.9 21
PDB header:oxidoreductase
Chain: F: PDB Molecule:nadh dehydrogenase [ubiquinone] flavoprotein 1,
PDBTitle: structure of mammalian respiratory complex i, class2
58c5wvmA_



not modelled 21.9 26
PDB header:sugar binding protein
Chain: A: PDB Molecule:maltose-binding periplasmic protein,two-component system
PDBTitle: crystal structure of baes cocrystallized with 2 mm indole
59c1bkvB_



not modelled 21.3 38
PDB header:structural protein
Chain: B: PDB Molecule:t3-785;
PDBTitle: collagen
60c1bkvC_



not modelled 21.3 38
PDB header:structural protein
Chain: C: PDB Molecule:t3-785;
PDBTitle: collagen
61c3lhlA_



not modelled 21.1 19
PDB header:hydrolase
Chain: A: PDB Molecule:putative agmatinase;
PDBTitle: crystal structure of a putative agmatinase from clostridium difficile
62d1uana_



not modelled 20.5 15
Fold:LmbE-like
Superfamily:LmbE-like
Family:LmbE-like
63d1pq3a_



not modelled 20.3 10
Fold:Arginase/deacetylase
Superfamily:Arginase/deacetylase
Family:Arginase-like amidino hydrolases
64c2vfjA_



not modelled 20.2 17
PDB header:hydrolase
Chain: A: PDB Molecule:tumor necrosis factor;
PDBTitle: structure of the a20 ovarian tumour (otu) domain
65c5cgzA_



not modelled 20.1 16
PDB header:lyase
Chain: A: PDB Molecule:4-oxalmesaconate hydratase;
PDBTitle: crystal structure of galb, the 4-carboxy-2-hydroxymuconate hydratase,2 from pseuodomonas putida kt2440
66c3ahrA_



not modelled 20.0 25
PDB header:oxidoreductase
Chain: A: PDB Molecule:ero1-like protein alpha;
PDBTitle: inactive human ero1
67c5oejB_



not modelled 19.6 19
PDB header:transcription
Chain: B: PDB Molecule:tra1 subunit within the chromatin modifying complex saga;
PDBTitle: structure of tra1 subunit within the chromatin modifying complex saga
68c3bkhA_



not modelled 19.5 29
PDB header:hydrolase
Chain: A: PDB Molecule:lytic transglycosylase;
PDBTitle: crystal structure of the bacteriophage phikz lytic2 transglycosylase, gp144
69c5gxyA_



not modelled 19.2 23
PDB header:hydrolase
Chain: A: PDB Molecule:glucanase;
PDBTitle: crystal structure of endoglucanase celq from clostridium thermocellum2 complexed with cellobiose and tris
70c1ryiB_



not modelled 18.6 7
PDB header:oxidoreductase
Chain: B: PDB Molecule:glycine oxidase;
PDBTitle: structure of glycine oxidase with bound inhibitor glycolate
71c5eduB_



not modelled 18.6 20
PDB header:hydrolase/hydrolase inhibitor
Chain: B: PDB Molecule:maltose-binding periplasmic protein, histone deacetylase 6
PDBTitle: crystal structure of human histone deacetylase 6 catalytic domain 2 in2 complex with trichostatin a
72d3fapb_



not modelled 18.0 19
Fold:Four-helical up-and-down bundle
Superfamily:FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
Family:FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
73c5frgA_



not modelled 17.9 50
PDB header:protein binding
Chain: A: PDB Molecule:formin-binding protein 1-like;
PDBTitle: the nmr structure of the cdc42-interacting region of toca1
74c5xomB_



not modelled 17.3 26
PDB header:transferase
Chain: B: PDB Molecule:glycosaminoglycan xylosylkinase;
PDBTitle: hydra fam20
75c2xn1B_



not modelled 17.2 20
PDB header:hydrolase
Chain: B: PDB Molecule:alpha-galactosidase;
PDBTitle: structure of alpha-galactosidase from lactobacillus acidophilus ncfm2 with tris
76c5t1dC_



not modelled 17.1 10
PDB header:viral protein
Chain: C: PDB Molecule:glycoprotein 42;
PDBTitle: crystal structure of ebv ghgl/gp42/e1d1 complex
77c2dmiA_



not modelled 16.8 13
PDB header:transcription
Chain: A: PDB Molecule:teashirt homolog 3;
PDBTitle: solution structure of the first and the second zf-c2h2 like2 domains of human teashirt homolog 3
78c2eqfA_



not modelled 16.7 44
PDB header:hydrolase
Chain: A: PDB Molecule:tumor necrosis factor, alpha-induced protein 3;
PDBTitle: solution structure of the 7th a20-type zinc finger domain2 from human tumor necrosis factor, alpha-induced protein3
79c4rqoB_



not modelled 16.6 32
PDB header:lyase
Chain: B: PDB Molecule:l-serine dehydratase;
PDBTitle: crystal structure of l-serine dehydratase from legionella pneumophila
80c5meeB_



not modelled 16.5 33
PDB header:oxidoreductase
Chain: B: PDB Molecule:arachidonate 15-lipoxygenase;
PDBTitle: cyanothece lipoxygenase 2 (csplox2) variant - l304v
81c5ojsT_



not modelled 16.4 20
PDB header:transcription
Chain: T: PDB Molecule:transcription-associated protein 1;
PDBTitle: cryo-em structure of the saga and nua4 coactivator subunit tra1
82c2k42B_



not modelled 16.4 47
PDB header:signaling protein
Chain: B: PDB Molecule:espfu;
PDBTitle: solution structure of the gtpase binding domain of wasp in2 complex with espfu, an ehec effector
83c3elyA_



not modelled 16.4 67
PDB header:transferase
Chain: A: PDB Molecule:methyltransferase;
PDBTitle: wesselsbron virus methyltransferase in complex with adohcy
84c1pggB_



not modelled 16.0 20
PDB header:oxidoreductase
Chain: B: PDB Molecule:prostaglandin h2 synthase-1;
PDBTitle: prostaglandin h2 synthase-1 complexed with 1-(4-iodobenzoyl)-5-2 methoxy-2-methylindole-3-acetic acid (iodoindomethacin), trans model
85c1ht8B_



not modelled 16.0 20
PDB header:oxidoreductase
Chain: B: PDB Molecule:prostaglandin h2 synthase-1;
PDBTitle: the 2.7 angstrom resolution model of ovine cox-1 complexed with2 alclofenac
86c3kfvA_



not modelled 16.0 19
PDB header:cell adhesion
Chain: A: PDB Molecule:tight junction protein zo-3;
PDBTitle: crystal structure of the sh3-kinase fragment of tight junction protein2 3 (tjp3) in apo-form
87c3mmrA_



not modelled 15.9 12
PDB header:hydrolase
Chain: A: PDB Molecule:arginase;
PDBTitle: structure of plasmodium falciparum arginase in complex with abh
88d2nn6g2



not modelled 15.8 67
Fold:Barrel-sandwich hybrid
Superfamily:Ribosomal L27 protein-like
Family:ECR1 N-terminal domain-like
89d1tl2a_



not modelled 15.8 29
Fold:5-bladed beta-propeller
Superfamily:Tachylectin-2
Family:Tachylectin-2
90c3c7tB_



not modelled 15.8 25
PDB header:hydrolase
Chain: B: PDB Molecule:ecdysteroid-phosphate phosphatase;
PDBTitle: crystal structure of the ecdysone phosphate phosphatase, eppase, from2 bombix mori in complex with tungstate
91c2oxtC_



not modelled 15.8 67
PDB header:viral protein
Chain: C: PDB Molecule:nucleoside-2'-o-methyltransferase;
PDBTitle: crystal structure of meaban virus nucleoside-2'-o-2 methyltransferase
92d2awna1



not modelled 15.8 38
Fold:OB-fold
Superfamily:MOP-like
Family:ABC-transporter additional domain
93c1vi7A_



not modelled 15.8 13
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein yigz;
PDBTitle: crystal structure of an hypothetical protein
94d1ppjd1



not modelled 15.7 30
Fold:Cytochrome c
Superfamily:Cytochrome c
Family:Cytochrome bc1 domain
95c6elsA_



not modelled 15.6 14
PDB header:oxidoreductase
Chain: A: PDB Molecule:polyphenol oxidase, chloroplastic;
PDBTitle: structure of latent apple tyrosinase (mdppo1)
96c4fddB_



not modelled 15.5 43
PDB header:transport protein
Chain: B: PDB Molecule:rna-binding protein fus;
PDBTitle: crystal structure of kap beta2-py-nls
97c4fq3B_



not modelled 15.5 43
PDB header:protein binding
Chain: B: PDB Molecule:fusion (involved in t(12;16) in malignant liposarcoma);
PDBTitle: crystal structure of transportin/fus-nls
98c5yvhB_



not modelled 15.5 43
PDB header:protein transport/rna binding protein
Chain: B: PDB Molecule:rna-binding protein fus;
PDBTitle: crystal structure of karyopherin beta2 in complex with fus(371-526)
99c5yviB_



not modelled 15.5 43
PDB header:protein transport/rna binding protein
Chain: B: PDB Molecule:rna-binding protein fus;
PDBTitle: crystal structure of karyopherin beta2 in complex with fus(456-526)

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Transmembrane helix prediction 

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