1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	P	G	A	R	E	L	T	L	R	V	E	R	G	A	L	F	R	R	R	W	A	A	S	A	A	S	S	A	R	A	A	I	R	R	D	P	R	R	C	A	L	G	T	R	P	R	W	V	S	F	L	V	I	V	L	V	I	M	N
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?								?									?	?	?	?	?	?	?	?	?	?	?	?							?																		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	V	T	A	H	P	K	Y	P	N	D	P	L	A	L	V	L	I	E	L	R	H	P	R	T	E	P	P	V	P	S	A	I	S	I	L	K	E	E	L	A	R	W	T	P	I	L	E	Q	E	E	V	R	Q	V	N	L	E	T	G
Secondary structure
SS confidence
Disorder			?	?	?	?	?																					?	?	?	?																				?	?	?				?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	H	T	A	H	S	Q	K	K	L	V	A	R	D	R	R	T	A	I	T	F	R	P	D	A	M	T	L	E	V	T	D	Y	P	G	W	E	E	F	R	S	I	V	H	A	M	V	T	A	R	Q	D	V	A	P	V	D	G	C	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																																																		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		R	I	G	L	R	Y	I	N	E	I	R	A	S	L	A	E	P	S	G	W	A	Y	W	V	A	E	S	L	L	G	P	G	T	Q	L	A	D	L	K	L	T	T	T	A	Q	R	H	V	I	Q	C	E	G	P	E	P	G	D	S	L
Secondary structure
SS confidence
Disorder														?	?	?	?	?										?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		T	L	R	Y	A	G	A	R	G	A	V	I	Q	S	T	P	F	L	Q	R	L	K	E	P	P	A	E	G	D	F	F	L	I	D	I	D	S	A	W	S	D	P	C	K	G	I	P	A	L	D	A	H	L	V	D	E	V	A	E	R
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.
Sequence		L	H	T	P	I	G	P	L	F	E	S	L	I	T	S	E	L	R	T	K	V	L	Q	Q	P	G	Q	E
Secondary structure
SS confidence
Disorder																									?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 29%) Alpha helix ( 34%) Beta strand ( 23%)

Rank Aligned region

PDB 1f4n chain B Region: 288 - 313 Aligned: 26 Modelled: 26 Confidence: 75.9% Identity: 27% Fold: ROP-like Superfamily: ROP protein Family: ROP protein Phyre2 PDB 1f4n chain A Region: 288 - 313 Aligned: 26 Modelled: 26 Confidence: 74.9% Identity: 27% Fold: ROP-like Superfamily: ROP protein Family: ROP protein Phyre2 PDB 1yo7 chain A Region: 288 - 318 Aligned: 31 Modelled: 31 Confidence: 73.7% Identity: 29% PDB header:replication regulator Chain: A: PDB Molecule:regulatory protein rop; PDBTitle: re-engineering topology of the homodimeric rop protein into a single-2 chain 4-helix bundle Phyre2 PDB 2ijk chain A domain 1 Region: 288 - 316 Aligned: 29 Modelled: 29 Confidence: 70.3% Identity: 28% Fold: ROP-like Superfamily: ROP protein Family: ROP protein Phyre2 PDB 1gto chain A Region: 288 - 316 Aligned: 29 Modelled: 29 Confidence: 65.0% Identity: 24% Fold: ROP-like Superfamily: ROP protein Family: ROP protein Phyre2 PDB 1qx8 chain A Region: 291 - 312 Aligned: 22 Modelled: 22 Confidence: 45.9% Identity: 23% Fold: ROP-like Superfamily: ROP protein Family: ROP protein Phyre2 PDB 1nkd chain A Region: 290 - 312 Aligned: 23 Modelled: 23 Confidence: 35.0% Identity: 26% Fold: ROP-like Superfamily: ROP protein Family: ROP protein Phyre2 PDB 2ltl chain A Region: 124 - 177 Aligned: 54 Modelled: 54 Confidence: 31.7% Identity: 9% PDB header:electron transport Chain: A: PDB Molecule:nifu-like protein, mitochondrial; PDBTitle: solution nmr structure of nifu-like protein from saccharomyces2 cerevisiae, northeast structural genomics consortium (nesg) target3 yr313a Phyre2 PDB 4xtr chain G Region: 47 - 59 Aligned: 13 Modelled: 13 Confidence: 27.1% Identity: 54% PDB header:hydrolase/transport protein Chain: G: PDB Molecule:pep12p; PDBTitle: structure of get3 bound to the transmembrane domain of pep12 Phyre2 PDB 1e8o chain A Region: 153 - 169 Aligned: 17 Modelled: 17 Confidence: 22.0% Identity: 35% Fold: Signal recognition particle alu RNA binding heterodimer, SRP9/14 Superfamily: Signal recognition particle alu RNA binding heterodimer, SRP9/14 Family: Signal recognition particle alu RNA binding heterodimer, SRP9/14 Phyre2 PDB 2mbl chain A Region: 138 - 240 Aligned: 102 Modelled: 103 Confidence: 20.5% Identity: 21% PDB header:de novo protein Chain: A: PDB Molecule:top7 fold protein top7m13; PDBTitle: solution nmr structure of de novo designed top7 fold protein top7m13,2 northeast structural genomics consortium (nesg) target or33 Phyre2 PDB 3tj1 chain A Region: 58 - 116 Aligned: 59 Modelled: 59 Confidence: 19.2% Identity: 20% PDB header:transcription Chain: A: PDB Molecule:rna polymerase i-specific transcription initiation factor PDBTitle: crystal structure of rna polymerase i transcription initiation factor2 rrn3 Phyre2 PDB 2k1h chain A Region: 128 - 168 Aligned: 41 Modelled: 41 Confidence: 18.6% Identity: 15% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein ser13; PDBTitle: solution nmr structure of ser13 from staphylococcus epidermidis.2 northeast structural genomics consortium target ser13 Phyre2 PDB 2ffm chain A domain 1 Region: 129 - 168 Aligned: 40 Modelled: 40 Confidence: 17.2% Identity: 15% Fold: Hypothetical protein SAV1430 Superfamily: Hypothetical protein SAV1430 Family: Hypothetical protein SAV1430 Phyre2 PDB 5ldx chain P Region: 68 - 104 Aligned: 37 Modelled: 37 Confidence: 16.4% Identity: 19% PDB header:oxidoreductase Chain: P: PDB Molecule:nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit PDBTitle: structure of mammalian respiratory complex i, class3. Phyre2 PDB 5ldw chain P Region: 68 - 104 Aligned: 37 Modelled: 37 Confidence: 16.4% Identity: 19% PDB header:oxidoreductase Chain: P: PDB Molecule:nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit PDBTitle: structure of mammalian respiratory complex i, class1 Phyre2 PDB 5lc5 chain P Region: 68 - 104 Aligned: 37 Modelled: 37 Confidence: 16.4% Identity: 19% PDB header:oxidoreductase Chain: P: PDB Molecule:nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit PDBTitle: structure of mammalian respiratory complex i, class2 Phyre2 PDB 5o31 chain P Region: 68 - 104 Aligned: 37 Modelled: 37 Confidence: 16.3% Identity: 19% PDB header:oxidoreductase Chain: P: PDB Molecule:nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit PDBTitle: mitochondrial complex i in the deactive state Phyre2 PDB 4uzm chain A Region: 177 - 228 Aligned: 50 Modelled: 52 Confidence: 15.6% Identity: 20% PDB header:structural protein Chain: A: PDB Molecule:putative membrane protein igaa homolog; PDBTitle: shotgun proteolysis: a practical application Phyre2 PDB 1q1o chain A Region: 144 - 189 Aligned: 43 Modelled: 46 Confidence: 15.5% Identity: 14% Fold: beta-Grasp (ubiquitin-like) Superfamily: CAD & PB1 domains Family: PB1 domain Phyre2 1 d1f4nb_ 2 d1f4na_ 3 c1yo7A_ 4 d2ijka1 5 d1gtoa_ 6 d1qx8a_ 7 d1nkda_ 8 c2ltlA_ 9 c4xtrG_ 10 d1e8oa_ 11 c2mblA_ 12 c3tj1A_ 13 c2k1hA_ 14 d2ffma1 15 c5ldxp_ 16 c5ldwp_ 17 c5lc5p_ 18 c5o31p_ 19 c4uzmA_ 20 d1q1oa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61