1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Y	T	A	E	N	A	P	G	V	A	V	L	L	S	G	D	A	D	V	P	G	P	L	T	G	L	P	T	H	Q	D	N	L	D	T	V	I	G	R	Y	S	R	L	I	V	V	G	A	D	A	D	L	G	A	V	L	T	R	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?													?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	R	T	D	R	L	D	V	E	V	G	Y	V	P	R	R	R	S	P	A	T	R	A	Y	R	L	P	A	G	R	R	A	A	R	R	A	R	C	G	V	A	R	R	V	P	L	I	R	D	E	T	G	S	V	I	V	G	R	A	Q
Secondary structure
SS confidence
Disorder																					?	?	?					?		?									?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		W	L	P	A	E	E	Q	A	L	I	H	G	E	A	V	V	D	D	T	V	L	F	D	G	D	V	A	G	V	C	I	E	P	T	L	T	L	P	G	L	R	A	A	V	D	G	A	G	K	W	R	R	W	I	G	G	R	A	A	Q
Secondary structure
SS confidence
Disorder			?		?	?	?	?																												?	?		?							?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.
Sequence		L	G	T	T	G	A	A	V	L	R	D	G	V	A	A	P	R	P	V	R	R	S	T	F	Y	R	N	V	E	G	W	L	L	V	R
Secondary structure
SS confidence
Disorder															?	?	?															?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 23%) Alpha helix ( 14%) Beta strand ( 42%)

Rank Aligned region

PDB 2jgr chain A domain 1 Region: 10 - 141 Aligned: 132 Modelled: 130 Confidence: 99.7% Identity: 13% Fold: NAD kinase/diacylglycerol kinase-like Superfamily: NAD kinase/diacylglycerol kinase-like Family: Diacylglycerol kinase-like Phyre2 PDB 2bon chain B Region: 10 - 122 Aligned: 113 Modelled: 113 Confidence: 99.7% Identity: 14% PDB header:transferase Chain: B: PDB Molecule:lipid kinase; PDBTitle: structure of an escherichia coli lipid kinase (yegs) Phyre2 PDB 2bon chain A domain 1 Region: 10 - 122 Aligned: 113 Modelled: 113 Confidence: 99.7% Identity: 14% Fold: NAD kinase/diacylglycerol kinase-like Superfamily: NAD kinase/diacylglycerol kinase-like Family: Diacylglycerol kinase-like Phyre2 PDB 2qv7 chain A Region: 10 - 108 Aligned: 98 Modelled: 99 Confidence: 99.6% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:diacylglycerol kinase dgkb; PDBTitle: crystal structure of diacylglycerol kinase dgkb in complex with adp2 and mg Phyre2 PDB 3s40 chain C Region: 11 - 108 Aligned: 97 Modelled: 98 Confidence: 99.6% Identity: 14% PDB header:transferase Chain: C: PDB Molecule:diacylglycerol kinase; PDBTitle: the crystal structure of a diacylglycerol kinases from bacillus2 anthracis str. sterne Phyre2 PDB 2p1r chain A domain 1 Region: 10 - 122 Aligned: 113 Modelled: 108 Confidence: 99.6% Identity: 14% Fold: NAD kinase/diacylglycerol kinase-like Superfamily: NAD kinase/diacylglycerol kinase-like Family: Diacylglycerol kinase-like Phyre2 PDB 2qv7 chain A domain 1 Region: 10 - 108 Aligned: 98 Modelled: 99 Confidence: 99.6% Identity: 17% Fold: NAD kinase/diacylglycerol kinase-like Superfamily: NAD kinase/diacylglycerol kinase-like Family: Diacylglycerol kinase-like Phyre2 PDB 4wer chain A Region: 11 - 108 Aligned: 97 Modelled: 98 Confidence: 99.6% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:diacylglycerol kinase catalytic domain protein; PDBTitle: crystal structure of diacylglycerol kinase catalytic domain protein2 from enterococcus faecalis v583 Phyre2 PDB 3vzd chain B Region: 12 - 108 Aligned: 97 Modelled: 97 Confidence: 99.5% Identity: 18% PDB header:transferase/inhibitor Chain: B: PDB Molecule:sphingosine kinase 1; PDBTitle: crystal structure of sphingosine kinase 1 with inhibitor and adp Phyre2 PDB 1u0t chain A Region: 39 - 153 Aligned: 112 Modelled: 115 Confidence: 97.8% Identity: 12% Fold: NAD kinase/diacylglycerol kinase-like Superfamily: NAD kinase/diacylglycerol kinase-like Family: NAD kinase-like Phyre2 PDB 3afo chain B Region: 33 - 153 Aligned: 119 Modelled: 121 Confidence: 97.2% Identity: 14% PDB header:transferase Chain: B: PDB Molecule:nadh kinase pos5; PDBTitle: crystal structure of yeast nadh kinase complexed with nadh Phyre2 PDB 2an1 chain D Region: 33 - 153 Aligned: 118 Modelled: 121 Confidence: 97.1% Identity: 19% PDB header:transferase Chain: D: PDB Molecule:putative kinase; PDBTitle: structural genomics, the crystal structure of a putative kinase from2 salmonella typhimurim lt2 Phyre2 PDB 1yt5 chain A Region: 39 - 153 Aligned: 110 Modelled: 115 Confidence: 97.1% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:inorganic polyphosphate/atp-nad kinase; PDBTitle: crystal structure of nad kinase from thermotoga maritima Phyre2 PDB 3pfn chain B Region: 27 - 153 Aligned: 121 Modelled: 127 Confidence: 96.8% Identity: 12% PDB header:transferase Chain: B: PDB Molecule:nad kinase; PDBTitle: crystal structure of human nad kinase Phyre2 PDB 1z0s chain A domain 1 Region: 35 - 153 Aligned: 115 Modelled: 119 Confidence: 92.6% Identity: 13% Fold: NAD kinase/diacylglycerol kinase-like Superfamily: NAD kinase/diacylglycerol kinase-like Family: NAD kinase-like Phyre2 PDB 1z0z chain C Region: 35 - 153 Aligned: 115 Modelled: 119 Confidence: 92.6% Identity: 13% PDB header:transferase Chain: C: PDB Molecule:probable inorganic polyphosphate/atp-nad kinase; PDBTitle: crystal structure of a nad kinase from archaeoglobus2 fulgidus in complex with nad Phyre2 PDB 2i2a chain A Region: 40 - 153 Aligned: 113 Modelled: 114 Confidence: 92.6% Identity: 9% PDB header:transferase Chain: A: PDB Molecule:probable inorganic polyphosphate/atp-nad kinase 1; PDBTitle: crystal structure of lmnadk1 from listeria monocytogenes Phyre2 PDB 3opy chain E Region: 12 - 74 Aligned: 63 Modelled: 63 Confidence: 64.0% Identity: 11% PDB header:transferase Chain: E: PDB Molecule:6-phosphofructo-1-kinase alpha-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state Phyre2 PDB 3opy chain G Region: 12 - 74 Aligned: 63 Modelled: 63 Confidence: 63.2% Identity: 11% PDB header:transferase Chain: G: PDB Molecule:6-phosphofructo-1-kinase alpha-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state Phyre2 PDB 2f48 chain A domain 1 Region: 40 - 74 Aligned: 35 Modelled: 35 Confidence: 54.5% Identity: 20% Fold: Phosphofructokinase Superfamily: Phosphofructokinase Family: Phosphofructokinase Phyre2 1 d2jgra1 2 c2bonB_ 3 d2bona1 4 c2qv7A_ 5 c3s40C_ 6 d2p1ra1 7 d2qv7a1 8 c4werA_ 9 c3vzdB_ 10 d1u0ta_ 11 c3afoB_ 12 c2an1D_ 13 c1yt5A_ 14 c3pfnB_ 15 d1z0sa1 16 c1z0zC_ 17 c2i2aA_ 18 c3opyE_ 19 c3opyG_ 20 d2f48a1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99