1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	L	A	N	R	A	A	S	A	E	T	A	V	T	Q	R	H	L	R	R	L	W	A	L	P	G	T	Q	L	A	V	V	A	W	P	S	T	R	R	D	R	L	F	G	S	W	H	Y	W	W	Q	A	H	L	L	D	C	L	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	A	Q	L	R	D	P	Q	P	Q	R	R	A	R	I	N	R	Q	V	R	S	H	R	V	R	N	N	F	S	W	L	N	S	Y	Y	D	D	M	A	W	L	A	L	A	L	E	R	A	D	R	V	A	G	V	R	R	R	R	A	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	K	L	T	N	Q	F	V	E	A	W	V	P	E	D	G	G	G	I	P	W	R	K	Q	D	Q	F	F	N	A	P	A	N	G	P	A	G	L	F	L	A	R	Y	P	D	Q	Y	G	K	R	L	K	R	A	E	Q	M	A	D	W
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		I	D	R	T	L	I	D	P	E	T	H	L	V	F	D	G	I	K	A	G	S	L	V	R	A	Q	Y	T	Y	C	Q	G	V	V	L	G	L	E	T	E	L	A	V	R	T	G	P	A	A	R	A	R	H	C	A	R	V	H	R	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		V	A	A	V	N	E	H	M	A	P	L	G	V	L	R	G	A	G	G	G	D	G	G	L	F	A	G	I	T	A	R	Y	L	A	L	V	A	T	T	L	P	G	D	S	A	D	D	A	A	A	R	D	T	A	R	A	I	V	L	A
Secondary structure
SS confidence
Disorder																																														?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		S	A	Q	S	A	W	D	Y	R	Q	T	V	D	G	L	P	V	F	G	A	F	W	D	R	E	A	E	L	P	T	A	G	G	E	Q	A	R	S	V	R	G	A	V	H	S	S	A	I	A	E	R	D	L	S	V	Q	L	S	G	W
Secondary structure
SS confidence
Disorder											?				?	?											?			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.
Sequence		M	L	M	E	A	A	H	S	A	A	A	V	S	S	L	G
Secondary structure
SS confidence
Disorder															?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 11%) Alpha helix ( 56%) Beta strand ( 2%)

Rank Aligned region

PDB 3k7x chain A Region: 4 - 371 Aligned: 329 Modelled: 347 Confidence: 100.0% Identity: 28% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lin0763 protein; PDBTitle: crystal structure of the lin0763 protein from listeria innocua.2 northeast structural genomics consortium target lkr23. Phyre2 PDB 4c1s chain A Region: 4 - 373 Aligned: 336 Modelled: 347 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:glycoside hydrolase family 76 mannosidase; PDBTitle: glycoside hydrolase family 76 (mannosidase) bt3792 from2 bacteroides thetaiotaomicron vpi-5482 Phyre2 PDB 4boj chain C Region: 4 - 363 Aligned: 325 Modelled: 336 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: C: PDB Molecule:alpha-1,6-mannanase; PDBTitle: crystal structure of bacillus circulans tn-31 aman6 in2 complex with mannobiose Phyre2 PDB 4mu9 chain B Region: 6 - 369 Aligned: 324 Modelled: 341 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: B: PDB Molecule:glycoside hydrolase family 73; PDBTitle: crystal structure of a putative glycosylhydrolase (bt_3782) from2 bacteroides thetaiotaomicron vpi-5482 at 1.89 a resolution Phyre2 PDB 4v1s chain A Region: 18 - 330 Aligned: 289 Modelled: 313 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:alpha-1,6-mannanase; PDBTitle: structure of the gh76 alpha-mannanase bt2949 from2 bacteroides thetaiotaomicron Phyre2 PDB 2d5j chain A domain 1 Region: 47 - 371 Aligned: 301 Modelled: 304 Confidence: 99.9% Identity: 18% Fold: alpha/alpha toroid Superfamily: Six-hairpin glycosidases Family: Glycosyl Hydrolase Family 88 Phyre2 PDB 2zzr chain A Region: 48 - 375 Aligned: 304 Modelled: 307 Confidence: 99.9% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:unsaturated glucuronyl hydrolase; PDBTitle: crystal structure of unsaturated glucuronyl hydrolase from2 streptcoccus agalactiae Phyre2 PDB 3wiw chain A Region: 46 - 375 Aligned: 299 Modelled: 312 Confidence: 99.9% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:glycosyl hydrolase family 88; PDBTitle: crystal structure of unsaturated glucuronyl hydrolase specific for2 heparin Phyre2 PDB 4ce7 chain B Region: 50 - 298 Aligned: 246 Modelled: 249 Confidence: 99.8% Identity: 13% PDB header:hydrolase Chain: B: PDB Molecule:unsaturated 3s-rhamnoglycuronyl hydrolase; PDBTitle: crystal structure of a novel unsaturated beta-glucuronyl2 hydrolase enzyme, belonging to family gh105, involved in3 ulvan degradation Phyre2 PDB 4xuv chain B Region: 42 - 300 Aligned: 254 Modelled: 259 Confidence: 99.8% Identity: 11% PDB header:hydrolase Chain: B: PDB Molecule:glycoside hydrolase family 105 protein; PDBTitle: crystal structure of a glycoside hydrolase family 105 (gh105) enzyme2 from thielavia terrestris Phyre2 PDB 5zhb chain B Region: 52 - 321 Aligned: 243 Modelled: 252 Confidence: 99.6% Identity: 14% PDB header:isomerase Chain: B: PDB Molecule:cellobiose 2-epimerase; PDBTitle: structure of cellobiose 2-epimerase from bacillus thermoamylovorans2 b4167 Phyre2 PDB 1nc5 chain A Region: 35 - 300 Aligned: 264 Modelled: 266 Confidence: 99.6% Identity: 9% Fold: alpha/alpha toroid Superfamily: Six-hairpin glycosidases Family: Hypothetical protein YteR Phyre2 PDB 5x32 chain B Region: 7 - 262 Aligned: 247 Modelled: 256 Confidence: 99.6% Identity: 13% PDB header:isomerase Chain: B: PDB Molecule:n-acylglucosamine 2-epimerase; PDBTitle: crystal structure of d-mannose isomerase Phyre2 PDB 3gt5 chain A Region: 8 - 280 Aligned: 267 Modelled: 273 Confidence: 99.6% Identity: 13% PDB header:isomerase Chain: A: PDB Molecule:n-acetylglucosamine 2-epimerase; PDBTitle: crystal structure of an n-acetylglucosamine 2-epimerase family protein2 from xylella fastidiosa Phyre2 PDB 3wkg chain A Region: 56 - 325 Aligned: 261 Modelled: 268 Confidence: 99.6% Identity: 15% PDB header:isomerase Chain: A: PDB Molecule:cellobiose 2-epimerase; PDBTitle: crystal structure of cellobiose 2-epimerase in complex with2 glucosylmannose Phyre2 PDB 4wu0 chain B Region: 35 - 300 Aligned: 260 Modelled: 266 Confidence: 99.5% Identity: 10% PDB header:hydrolase Chain: B: PDB Molecule:similar to yter (bacilus subtilis); PDBTitle: structural analysis of c. acetobutylicum atcc 824 glycoside hydrolase2 from family 105 Phyre2 PDB 5zig chain D Region: 52 - 325 Aligned: 260 Modelled: 269 Confidence: 99.5% Identity: 15% PDB header:isomerase Chain: D: PDB Molecule:cellobiose 2-epimerase; PDBTitle: the structure of cellobiose 2-epimerase from spirochaeta thermophila2 dsm 6192 Phyre2 PDB 4z4l chain A Region: 97 - 307 Aligned: 202 Modelled: 209 Confidence: 99.5% Identity: 13% PDB header:isomerase Chain: A: PDB Molecule:cellobiose 2-epimerase; PDBTitle: crystal structure of cellobiose 2-epimerase from caldicellulosiruptor2 saccharolyticus dsm 8903 Phyre2 PDB 5noa chain A Region: 35 - 314 Aligned: 258 Modelled: 280 Confidence: 99.5% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:family 88 glycosyl hydrolase; PDBTitle: polysaccharide lyase baccell_00875 Phyre2 PDB 3vw5 chain B Region: 52 - 310 Aligned: 240 Modelled: 259 Confidence: 99.4% Identity: 13% PDB header:isomerase Chain: B: PDB Molecule:cellobiose 2-epimerase; PDBTitle: crystal structure of sugar epimerase from ruminal bacterium Phyre2 1 c3k7xA_ 2 c4c1sA_ 3 c4bojC_ 4 c4mu9B_ 5 c4v1sA_ 6 d2d5ja1 7 c2zzrA_ 8 c3wiwA_ 9 c4ce7B_ 10 c4xuvB_ 11 c5zhbB_ 12 d1nc5a_ 13 c5x32B_ 14 c3gt5A_ 15 c3wkgA_ 16 c4wu0B_ 17 c5zigD_ 18 c4z4lA_ 19 c5noaA_ 20 c3vw5B_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99