1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	G	A	Q	L	I	G	H	E	G	D	E	Y	L	G	K	V	K	V	K	V	G	P	V	T	S	E	F	S	G	K	V	H	F	V	E	Q	D	R	N	Q	H	R	A	V	F	D	A	K	G	K	E	A	R	G	T	G	N	A
Secondary structure
SS confidence
Disorder		?	?	?	?			?	?	?	?	?	?																																						?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	A	T	V	A	A	Q	L	H	E	V	G	E	R	T	R	V	T	V	D	T	D	L	K	I	V	G	K	L	A	Q	F	G	S	G	M	L	Q	Q	V	S	E	K	L	L	G	Q	F	V	D	S	L	E	A	E	L	A	A	Q	S
Secondary structure
SS confidence
Disorder												?																		?			?	?																							?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.
Sequence		S	E	S	P	Q	G	T	P	P	A	T	E	A	A	P	I	D	L	L	Q	L	A	D	G	G	Q	L	K	K	Y	G	S	A	L	L	A	A	L	T	V	L	L	L	I	W	V	L	R	R	R	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?				?															?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 36%) Alpha helix ( 30%) Beta strand ( 41%) TM helix ( 10%) (View membrane topology prediction)

Rank Aligned region

PDB 2ns9 chain A domain 1 Region: 1 - 119 Aligned: 116 Modelled: 119 Confidence: 99.6% Identity: 16% Fold: TBP-like Superfamily: Bet v1-like Family: CoxG-like Phyre2 PDB 2pcs chain A domain 1 Region: 1 - 119 Aligned: 116 Modelled: 119 Confidence: 99.6% Identity: 20% Fold: TBP-like Superfamily: Bet v1-like Family: CoxG-like Phyre2 PDB 3p9v chain A Region: 1 - 116 Aligned: 111 Modelled: 116 Confidence: 99.4% Identity: 16% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: high resolution crystal structure of protein maqu_3174 from2 marinobacter aquaeolei, northeast structural genomics consortium3 target mqr197 Phyre2 PDB 2d4r chain A domain 1 Region: 1 - 121 Aligned: 115 Modelled: 116 Confidence: 98.2% Identity: 14% Fold: TBP-like Superfamily: Bet v1-like Family: oligoketide cyclase/dehydrase-like Phyre2 PDB 1t17 chain A Region: 1 - 118 Aligned: 112 Modelled: 118 Confidence: 97.9% Identity: 13% Fold: TBP-like Superfamily: Bet v1-like Family: oligoketide cyclase/dehydrase-like Phyre2 PDB 5wox chain A Region: 2 - 118 Aligned: 109 Modelled: 117 Confidence: 97.9% Identity: 8% PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: nmr solution structure of kany protein (ms6282) using two 4d-spectra Phyre2 PDB 3cnw chain A domain 1 Region: 1 - 113 Aligned: 107 Modelled: 113 Confidence: 97.5% Identity: 7% Fold: TBP-like Superfamily: Bet v1-like Family: Atu1531-like Phyre2 PDB 2kf2 chain A Region: 1 - 127 Aligned: 122 Modelled: 127 Confidence: 97.5% Identity: 11% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative polyketide cyclase; PDBTitle: solution nmr structure of of streptomyces coelicolor2 polyketide cyclase sco5315. northeast structural genomics3 consortium target rr365 Phyre2 PDB 3tfz chain B Region: 1 - 118 Aligned: 114 Modelled: 115 Confidence: 97.4% Identity: 12% PDB header:biosynthetic protein Chain: B: PDB Molecule:cyclase; PDBTitle: crystal structure of zhui aromatase/cyclase from streptomcyes sp.2 r1128 Phyre2 PDB 2le1 chain A Region: 1 - 117 Aligned: 111 Modelled: 117 Confidence: 97.3% Identity: 12% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution nmr structure of tfu_2981 from thermobifida fusca, northeast2 structural genomics consortium target tfr85a Phyre2 PDB 5z8o chain A Region: 1 - 117 Aligned: 108 Modelled: 117 Confidence: 97.2% Identity: 12% PDB header:unknown function Chain: A: PDB Molecule:cyclase/dehydrase; PDBTitle: structural of start superfamily protein msmeg_0129 from mycobacterium2 smegmatis Phyre2 PDB 4n0g chain C Region: 1 - 116 Aligned: 111 Modelled: 110 Confidence: 96.1% Identity: 11% PDB header:hydrolase/receptor Chain: C: PDB Molecule:abscisic acid receptor pyl13; PDBTitle: crystal structure of pyl13-pp2ca complex Phyre2 PDB 1xfs chain A Region: 20 - 115 Aligned: 95 Modelled: 94 Confidence: 96.0% Identity: 16% Fold: TBP-like Superfamily: Bet v1-like Family: AHSA1 domain Phyre2 PDB 3pu2 chain G Region: 28 - 118 Aligned: 79 Modelled: 90 Confidence: 95.9% Identity: 15% PDB header:structure genomics, unknown function Chain: G: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the q3j4m4_rhos4 protein from rhodobacter2 sphaeroides. northeast structural genomics consortium target rhr263. Phyre2 PDB 2ldk chain A Region: 1 - 125 Aligned: 117 Modelled: 125 Confidence: 95.9% Identity: 15% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution nmr structure of protein aaur_3427 from arthrobacter2 aurescens, northeast structural genomics consortium target aar96 Phyre2 PDB 2luz chain A Region: 23 - 137 Aligned: 100 Modelled: 115 Confidence: 95.2% Identity: 18% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:calu16; PDBTitle: solution nmr structure of calu16 from micromonospora echinospora,2 northeast structural genomics consortium (nesg) target mir12 Phyre2 PDB 3uid chain A Region: 4 - 120 Aligned: 109 Modelled: 117 Confidence: 95.0% Identity: 16% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of protein ms6760 from mycobacterium smegmatis Phyre2 PDB 2rer chain A domain 1 Region: 4 - 117 Aligned: 108 Modelled: 114 Confidence: 94.9% Identity: 10% Fold: TBP-like Superfamily: Bet v1-like Family: oligoketide cyclase/dehydrase-like Phyre2 PDB 2lgh chain A Region: 4 - 120 Aligned: 96 Modelled: 117 Confidence: 94.7% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution nmr structure of the ahsa1-like protein aha_2358 from2 aeromonas hydrophila refined with nh rdcs, northeast structural3 genomics consortium target ahr99. Phyre2 PDB 4xrw chain A Region: 1 - 121 Aligned: 114 Modelled: 121 Confidence: 94.6% Identity: 10% PDB header:lyase Chain: A: PDB Molecule:bexl; PDBTitle: crystal structure of the di-domain aro/cyc bexl from the be-7585a2 biosynthetic pathway Phyre2 1 d2ns9a1 2 d2pcsa1 3 c3p9vA_ 4 d2d4ra1 5 d1t17a_ 6 c5woxA_ 7 d3cnwa1 8 c2kf2A_ 9 c3tfzB_ 10 c2le1A_ 11 c5z8oA_ 12 c4n0gC_ 13 d1xfsa_ 14 c3pu2G_ 15 c2ldkA_ 16 c2luzA_ 17 c3uidA_ 18 d2rera1 19 c2lghA_ 20 c4xrwA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99