1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	D	H	A	I	G	L	L	D	R	L	G	E	G	A	R	V	V	A	G	G	H	S	L	L	P	M	M	K	L	R	I	A	N	P	E	Y	L	V	D	I	N	D	L	A	P	E	L	G	Y	V	V	V	G	G	I	N	N	P	N
Secondary structure
SS confidence
Disorder		?																																																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	V	R	L	G	A	M	T	R	H	R	E	I	L	D	S	D	A	L	A	A	V	C	P	I	F	R	D	A	E	R	V	I	A	D	P	V	V	R	N	R	G	T	L	G	G	S	L	C	Q	A	D	P	A	E	D	L	S	T	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		C	T	V	L	D	A	V	C	L	A	K	G	P	S	G	E	R	E	I	A	I	D	D	F	L	V	G	P	Y	E	T	A	L	A	H	N	E	V	L	I	E	V	R	I	P	L	R	H	N	T	S	S	A	Y	A	K	V	E	R	R
Secondary structure
SS confidence
Disorder														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	G	D	W	A	I	T	A	A	G	A	A	V	T	L	D	G	Q	T	I	L	A	A	R	V	G	L	T	A	V	N	P	D	P	V	A	L	A	E	L	S	A	G	L	V	G	Q	P	A	T	E	E	V	F	A	E	A	G	R	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.
Sequence		A	A	Q	A	C	T	P	V	T	D	V	R	G	T	A	E	Y	K	R	H	L	A	G	E	L	T	V	R	T	L	R	T	A	A	G	R	V	L	G	A	P	A	A	P	E	A
Secondary structure
SS confidence
Disorder									?																													?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 5%) Alpha helix ( 39%) Beta strand ( 26%)

Rank Aligned region

PDB 1n62 chain C Region: 1 - 277 Aligned: 272 Modelled: 277 Confidence: 100.0% Identity: 39% PDB header:oxidoreductase Chain: C: PDB Molecule:carbon monoxide dehydrogenase medium chain; PDBTitle: crystal structure of the mo,cu-co dehydrogenase (codh), n-2 butylisocyanide-bound state Phyre2 PDB 1t3q chain F Region: 1 - 277 Aligned: 270 Modelled: 277 Confidence: 100.0% Identity: 31% PDB header:oxidoreductase Chain: F: PDB Molecule:quinoline 2-oxidoreductase medium subunit; PDBTitle: crystal structure of quinoline 2-oxidoreductase from pseudomonas2 putida 86 Phyre2 PDB 1ffu chain F Region: 1 - 277 Aligned: 272 Modelled: 277 Confidence: 100.0% Identity: 39% PDB header:hydrolase Chain: F: PDB Molecule:cutm, flavoprotein of carbon monoxide PDBTitle: carbon monoxide dehydrogenase from hydrogenophaga2 pseudoflava which lacks the mo-pyranopterin moiety of the3 molybdenum cofactor Phyre2 PDB 3hrd chain C Region: 1 - 278 Aligned: 273 Modelled: 273 Confidence: 100.0% Identity: 23% PDB header:oxidoreductase Chain: C: PDB Molecule:nicotinate dehydrogenase fad-subunit; PDBTitle: crystal structure of nicotinate dehydrogenase Phyre2 PDB 4zoh chain B Region: 1 - 275 Aligned: 261 Modelled: 270 Confidence: 100.0% Identity: 34% PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase fad-binding subunit; PDBTitle: crystal structure of glyceraldehyde oxidoreductase Phyre2 PDB 2w3r chain G Region: 1 - 284 Aligned: 276 Modelled: 284 Confidence: 100.0% Identity: 20% PDB header:oxidoreductase Chain: G: PDB Molecule:xanthine dehydrogenase; PDBTitle: crystal structure of xanthine dehydrogenase (desulfo form)2 from rhodobacter capsulatus in complex with hypoxanthine Phyre2 PDB 1rm6 chain E Region: 1 - 275 Aligned: 266 Modelled: 267 Confidence: 100.0% Identity: 25% PDB header:oxidoreductase Chain: E: PDB Molecule:4-hydroxybenzoyl-coa reductase beta subunit; PDBTitle: structure of 4-hydroxybenzoyl-coa reductase from thauera2 aromatica Phyre2 PDB 3b9j chain J Region: 1 - 278 Aligned: 272 Modelled: 278 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: J: PDB Molecule:xanthine oxidase; PDBTitle: structure of xanthine oxidase with 2-hydroxy-6-methylpurine Phyre2 PDB 3etr chain M Region: 1 - 278 Aligned: 272 Modelled: 278 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: M: PDB Molecule:xanthine dehydrogenase/oxidase; PDBTitle: crystal structure of xanthine oxidase in complex with lumazine Phyre2 PDB 5y6q chain B Region: 1 - 277 Aligned: 266 Modelled: 277 Confidence: 100.0% Identity: 31% PDB header:oxidoreductase Chain: B: PDB Molecule:aldehyde oxidase medium subunit; PDBTitle: crystal structure of an aldehyde oxidase from methylobacillus sp.2 ky4400 Phyre2 PDB 1wyg chain A Region: 1 - 276 Aligned: 270 Modelled: 276 Confidence: 100.0% Identity: 18% PDB header:oxidoreductase Chain: A: PDB Molecule:xanthine dehydrogenase/oxidase; PDBTitle: crystal structure of a rat xanthine dehydrogenase triple mutant2 (c535a, c992r and c1324s) Phyre2 PDB 4uhx chain A Region: 1 - 276 Aligned: 270 Modelled: 271 Confidence: 100.0% Identity: 20% PDB header:oxidoreductase Chain: A: PDB Molecule:aldehyde oxidase; PDBTitle: human aldehyde oxidase in complex with phthalazine and thioridazine Phyre2 PDB 5g5h chain B Region: 1 - 274 Aligned: 254 Modelled: 264 Confidence: 100.0% Identity: 29% PDB header:oxidoreductase Chain: B: PDB Molecule:putative xanthine dehydrogenase yags fad-binding subunit; PDBTitle: escherichia coli periplasmic aldehyde oxidase r440h mutant Phyre2 PDB 3zyv chain A Region: 1 - 276 Aligned: 256 Modelled: 271 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: A: PDB Molecule:aox3; PDBTitle: crystal structure of the mouse liver aldehyde oxidase 3 (maox3) Phyre2 PDB 1n62 chain C domain 2 Region: 1 - 168 Aligned: 163 Modelled: 168 Confidence: 100.0% Identity: 43% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 1ffv chain C domain 2 Region: 1 - 169 Aligned: 164 Modelled: 169 Confidence: 100.0% Identity: 43% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 1t3q chain C domain 2 Region: 1 - 168 Aligned: 162 Modelled: 168 Confidence: 100.0% Identity: 33% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 1jro chain A domain 4 Region: 1 - 168 Aligned: 160 Modelled: 168 Confidence: 100.0% Identity: 16% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 1v97 chain A domain 6 Region: 1 - 169 Aligned: 163 Modelled: 169 Confidence: 100.0% Identity: 18% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 1rm6 chain B domain 2 Region: 1 - 167 Aligned: 160 Modelled: 167 Confidence: 100.0% Identity: 28% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 1 c1n62C_ 2 c1t3qF_ 3 c1ffuF_ 4 c3hrdC_ 5 c4zohB_ 6 c2w3rG_ 7 c1rm6E_ 8 c3b9jJ_ 9 c3etrM_ 10 c5y6qB_ 11 c1wygA_ 12 c4uhxA_ 13 c5g5hB_ 14 c3zyvA_ 15 d1n62c2 16 d1ffvc2 17 d1t3qc2 18 d1jroa4 19 d1v97a6 20 d1rm6b2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99