Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD0402c_(mmpL1)_480358_483234
DateTue Jul 23 14:50:47 BST 2019
Unique Job ID6106bfb25e2b4443
SequenceVRSQRLAGHL ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:63.918 Y:91.734 Z:94.148
Model (left) based on template c6ajjA_
Top template information
PDB header:membrane protein, hydrolase
Chain: A: PDB Molecule:drug exporters of the rnd superfamily-like protein,
PDBTitle: crystal structure of mycolic acid transporter mmpl3 from mycobacterium2 smegmatis complexed with ica38
Confidence and coverage
Confidence:100.0% Coverage: 74%
705 residues ( 74% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
938 residues ( 98%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c6ajjA_
100.0 21
PDB header:membrane protein, hydrolase
Chain: A: PDB Molecule:drug exporters of the rnd superfamily-like protein,
PDBTitle: crystal structure of mycolic acid transporter mmpl3 from mycobacterium2 smegmatis complexed with ica38
2c5lq3F_
100.0 14
PDB header:transport protein
Chain: F: PDB Molecule:cmeb;
PDBTitle: structures and transport dynamics of the campylobacter jejuni2 multidrug efflux pump cmeb
3c3k07A_
100.0 16
PDB header:transport protein
Chain: A: PDB Molecule:cation efflux system protein cusa;
PDBTitle: crystal structure of cusa
4c4mt1A_
100.0 13
PDB header:membrane protein, tranport protein
Chain: A: PDB Molecule:drug efflux protein;
PDBTitle: crystal structure of the neisseria gonorrhoeae mtrd inner membrane2 multidrug efflux pump
5c6owsB_
100.0 12
PDB header:membrane protein
Chain: B: PDB Molecule:efflux pump membrane transporter;
PDBTitle: cryo-em structure of an acinetobacter baumannii multidrug efflux pump
6c2v50A_
100.0 13
PDB header:membrane protein
Chain: A: PDB Molecule:multidrug resistance protein mexb;
PDBTitle: the missing part of the bacterial mexab-oprm system: structural2 determination of the multidrug exporter mexb
7c4k0eA_
100.0 14
PDB header:transport protein
Chain: A: PDB Molecule:heavy metal cation tricomponent efflux pump znea(czca-
PDBTitle: x-ray crystal structure of a heavy metal efflux pump, crystal form ii
8c1oy8A_
100.0 14
PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
9c6dmoA_
100.0 14
PDB header:protein binding
Chain: A: PDB Molecule:protein patched homolog 1;
PDBTitle: cryo-em structure of human ptch1 with three mutations2 l282q/t500f/p504l
10c5khnB_
100.0 18
PDB header:membrane protein
Chain: B: PDB Molecule:rnd transporter;
PDBTitle: crystal structures of the burkholderia multivorans hopanoid2 transporter hpnn
11c4k0eC_
100.0 14
PDB header:transport protein
Chain: C: PDB Molecule:heavy metal cation tricomponent efflux pump znea(czca-
PDBTitle: x-ray crystal structure of a heavy metal efflux pump, crystal form ii
12c6csxA_
100.0 13
PDB header:transport protein
Chain: A: PDB Molecule:multidrug efflux pump subunit acrb;
PDBTitle: single particles cryo-em structure of acrb d407a associated with lipid2 bilayer at 3.0 angstrom
13c3jd8A_
100.0 14
PDB header:membrane protein
Chain: A: PDB Molecule:niemann-pick c1 protein;
PDBTitle: cryo-em structure of the full-length human npc1 at 4.4 angstrom
14c3aqpB_
100.0 22
PDB header:membrane protein
Chain: B: PDB Molecule:probable secdf protein-export membrane protein;
PDBTitle: crystal structure of secdf, a translocon-associated membrane protein,2 from thermus thrmophilus
15c5xamA_
100.0 18
PDB header:membrane protein
Chain: A: PDB Molecule:protein translocase subunit secd;
PDBTitle: crystal structure of secdf in i form at 4 a resolution
16c5mg3D_
100.0 17
PDB header:chaperone
Chain: D: PDB Molecule:protein translocase subunit secd;
PDBTitle: em fitted model of bacterial holo-translocon
17d1iwga8
100.0 13
Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
18c5mg3F_
100.0 14
PDB header:chaperone
Chain: F: PDB Molecule:protein translocase subunit secf;
PDBTitle: em fitted model of bacterial holo-translocon
19d1iwga7
99.9 14
Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
20c5ensA_
99.6 11
PDB header:transport protein
Chain: A: PDB Molecule:multidrug efflux pump subunit acrb,multidrug efflux pump
PDBTitle: rhodamine bound structure of bacterial efflux pump.
21c4r86B_
not modelled 99.1 11
PDB header:protein transport
Chain: B: PDB Molecule:rnd family aminoglycoside/multidrug efflux pump;
PDBTitle: crystal structure of aminoglycoside/multidrug efflux system acrd from2 salmonella typhimurium
22d1iwga6
not modelled 92.6 10
Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
23c2yvxD_
not modelled 84.4 10
PDB header:transport protein
Chain: D: PDB Molecule:mg2+ transporter mgte;
PDBTitle: crystal structure of magnesium transporter mgte
24d1iwga2
not modelled 72.3 11
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
25d1wija_
not modelled 30.5 17
Fold:LEM/SAP HeH motif
Superfamily:DNA-binding domain of EIN3-like
Family:DNA-binding domain of EIN3-like
26d1iwga3
not modelled 26.6 7
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
27c4av3A_
not modelled 22.9 10
PDB header:hydrolase
Chain: A: PDB Molecule:k(+)-stimulated pyrophosphate-energized sodium pump;
PDBTitle: crystal structure of thermotoga maritima sodium pumping membrane2 integral pyrophosphatase with metal ions in active site
28c2kseA_
not modelled 17.1 33
PDB header:transferase
Chain: A: PDB Molecule:sensor protein qsec;
PDBTitle: backbone structure of the membrane domain of e. coli histidine kinase2 receptor qsec, center for structures of membrane proteins (csmp)3 target 4311c
29c1ciiA_
not modelled 14.9 11
PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia
30c5zlgA_
not modelled 14.0 11
PDB header:oxidoreductase
Chain: A: PDB Molecule:cytochrome b reductase 1;
PDBTitle: human duodenal cytochrome b (dcytb) in zinc ion and ascorbate bound2 form
31c6gctA_
not modelled 13.7 14
PDB header:membrane protein
Chain: A: PDB Molecule:neutral amino acid transporter b(0);
PDBTitle: cryo-em structure of the human neutral amino acid transporter asct2
32d1iwga4
not modelled 13.2 6
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
33c6bqiA_
not modelled 12.5 15
PDB header:translation
Chain: A: PDB Molecule:protein impact homolog;
PDBTitle: structure of two-domain translational regulator yih1 reveals a2 possible mechanism of action
34c4a01B_
not modelled 12.0 12
PDB header:hydrolase
Chain: B: PDB Molecule:proton pyrophosphatase;
PDBTitle: crystal structure of the h-translocating pyrophosphatase
35c2ww9B_
not modelled 11.1 0
PDB header:ribosome
Chain: B: PDB Molecule:protein transport protein sss1;
PDBTitle: cryo-em structure of the active yeast ssh1 complex bound to the yeast2 80s ribosome
36c1a87A_
not modelled 10.9 11
PDB header:bacteriocin
Chain: A: PDB Molecule:colicin n;
PDBTitle: colicin n
37d1a87a_
not modelled 10.9 11
Fold:Toxins' membrane translocation domains
Superfamily:Colicin
Family:Colicin
38c2mkaC_
not modelled 10.8 29
PDB header:immune system
Chain: C: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
39c2mkaB_
not modelled 10.8 29
PDB header:immune system
Chain: B: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
40c2mk9B_
not modelled 10.8 29
PDB header:immune system
Chain: B: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the dimeric transmembrane domain of toll-like2 receptor 3
41c2mkaA_
not modelled 10.8 29
PDB header:immune system
Chain: A: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
42c2mk9A_
not modelled 10.8 29
PDB header:immune system
Chain: A: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the dimeric transmembrane domain of toll-like2 receptor 3
43c4djiA_
not modelled 10.2 10
PDB header:transport protein
Chain: A: PDB Molecule:probable glutamate/gamma-aminobutyrate antiporter;
PDBTitle: structure of glutamate-gaba antiporter gadc
44c4fe1I_
not modelled 9.5 19
PDB header:photosynthesis
Chain: I: PDB Molecule:photosystem i reaction center subunit viii;
PDBTitle: improving the accuracy of macromolecular structure refinement at 7 a2 resolution
45d1jb0i_
not modelled 9.5 19
Fold:Single transmembrane helix
Superfamily:Subunit VIII of photosystem I reaction centre, PsaI
Family:Subunit VIII of photosystem I reaction centre, PsaI
46d2yvxa3
not modelled 9.3 8
Fold:MgtE membrane domain-like
Superfamily:MgtE membrane domain-like
Family:MgtE membrane domain-like
47c2n1pA_
not modelled 8.8 9
PDB header:viral protein
Chain: A: PDB Molecule:non-structural protein 5b, ns5b;
PDBTitle: structure of the c-terminal membrane domain of hcv ns5b protein
48c2k9pA_
not modelled 8.8 21
PDB header:membrane protein
Chain: A: PDB Molecule:pheromone alpha factor receptor;
PDBTitle: structure of tm1_tm2 in lppg micelles
49d1iwga5
not modelled 8.5 8
Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
50c3tijA_
not modelled 8.2 12
PDB header:membrane protein
Chain: A: PDB Molecule:nupc family protein;
PDBTitle: crystal structure of a concentrative nucleoside transporter from2 vibrio cholerae
51c3j2pD_
not modelled 8.0 21
PDB header:viral protein
Chain: D: PDB Molecule:small envelope protein m;
PDBTitle: cryoem structure of dengue virus envelope protein heterotetramer
52c6b2zf_
not modelled 7.9 18
PDB header:membrane protein
Chain: F: PDB Molecule:atp synthase subunit c, mitochondrial;
PDBTitle: cryo-em structure of the dimeric fo region of yeast mitochondrial atp2 synthase
53c2k1kA_
not modelled 7.6 16
PDB header:signaling protein
Chain: A: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 4.3
54c2k1kB_
not modelled 7.6 16
PDB header:signaling protein
Chain: B: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 4.3
55c2k1lA_
not modelled 7.6 16
PDB header:signaling protein
Chain: A: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 6.3
56c2k1lB_
not modelled 7.6 16
PDB header:signaling protein
Chain: B: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 6.3
57d3bzka3
not modelled 7.5 21
Fold:Tex N-terminal region-like
Superfamily:Tex N-terminal region-like
Family:Tex N-terminal region-like
58c6b8ht_
not modelled 7.5 18
PDB header:membrane protein
Chain: T: PDB Molecule:atp synthase subunit 9, mitochondrial;
PDBTitle: mosaic model of yeast mitochondrial atp synthase monomer
59c2bbjB_
not modelled 7.4 13
PDB header:metal transport/membrane protein
Chain: B: PDB Molecule:divalent cation transport-related protein;
PDBTitle: crystal structure of the cora mg2+ transporter
60c2m1hA_
not modelled 7.4 26
PDB header:transcription
Chain: A: PDB Molecule:transcription elongation factor s-ii;
PDBTitle: solution structure of a pwwp domain from trypanosoma brucei
61c5ireD_
not modelled 7.2 18
PDB header:virus
Chain: D: PDB Molecule:m protein;
PDBTitle: the cryo-em structure of zika virus
62c4cbfB_
not modelled 7.0 16
PDB header:virus
Chain: B: PDB Molecule:m protein;
PDBTitle: near-atomic resolution cryo-em structure of dengue serotype 4 virus
63c3v7oA_
not modelled 6.7 19
PDB header:transcription
Chain: A: PDB Molecule:minor nucleoprotein vp30;
PDBTitle: crystal structure of the c-terminal domain of ebola virus vp30 (strain2 reston-89)
64c4ev6E_
not modelled 6.6 21
PDB header:metal transport
Chain: E: PDB Molecule:magnesium transport protein cora;
PDBTitle: the complete structure of cora magnesium transporter from2 methanocaldococcus jannaschii
65c5wsnD_
not modelled 6.5 16
PDB header:virus
Chain: D: PDB Molecule:m protein;
PDBTitle: structure of japanese encephalitis virus
66c2qg8A_
not modelled 6.4 26
PDB header:transferase
Chain: A: PDB Molecule:acyl carrier protein synthase py06285;
PDBTitle: plasmodium yoelii acyl carrier protein synthase py06285 with adp bound
67c4b03D_
not modelled 6.3 16
PDB header:virus
Chain: D: PDB Molecule:dengue virus 1 prm protein;
PDBTitle: 6a electron cryomicroscopy structure of immature dengue virus serotype2 1
68c4or2A_
not modelled 5.9 14
PDB header:signaling protein
Chain: A: PDB Molecule:soluble cytochrome b562, metabotropic glutamate receptor 1;
PDBTitle: human class c g protein-coupled metabotropic glutamate receptor 1 in2 complex with a negative allosteric modulator
69c3zf7e_
not modelled 5.8 25
PDB header:ribosome
Chain: E: PDB Molecule:
PDBTitle: high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome
70c3l2uA_
not modelled 5.7 29
PDB header:recombination/dna
Chain: A: PDB Molecule:integrase;
PDBTitle: crystal structure of the prototype foamy virus (pfv)2 intasome in complex with magnesium and gs91373 (elvitegravir)
71c2lgxA_
not modelled 5.7 40
PDB header:cell adhesion
Chain: A: PDB Molecule:fermitin family homolog 2;
PDBTitle: nmr structure for kindle-2 n-terminus
72c2lonA_
not modelled 5.7 11
PDB header:membrane protein
Chain: A: PDB Molecule:hig1 domain family member 1b;
PDBTitle: backbone structure of human membrane protein higd1b
73c5gasN_
not modelled 5.6 11
PDB header:hydrolase
Chain: N: PDB Molecule:archaeal/vacuolar-type h+-atpase subunit i;
PDBTitle: thermus thermophilus v/a-atpase, conformation 2
74c5l2bC_
not modelled 5.5 11
PDB header:transport protein
Chain: C: PDB Molecule:nucleoside permease;
PDBTitle: structure of cntnw n149s, e332a in an outward-facing state
75c1p58E_
not modelled 5.5 12
PDB header:virus
Chain: E: PDB Molecule:envelope protein m;
PDBTitle: complex organization of dengue virus membrane proteins as revealed by2 9.5 angstrom cryo-em reconstruction
76c5ws4A_
not modelled 5.4 14
PDB header:membrane protein
Chain: A: PDB Molecule:macrolide export atp-binding/permease protein macb;
PDBTitle: crystal structure of tripartite-type abc transporter macb from2 acinetobacter baumannii
77c5ohdB_
not modelled 5.2 20
PDB header:membrane protein
Chain: B: PDB Molecule:growth hormone receptor;
PDBTitle: putative inactive (dormant) dimeric state of ghr transmembrane domain
78c5n9yB_
not modelled 5.2 10
PDB header:membrane protein
Chain: B: PDB Molecule:zinc transport protein zntb;
PDBTitle: the full-length structure of zntb
79c2kmcA_
not modelled 5.1 40
PDB header:cell adhesion
Chain: A: PDB Molecule:fermitin family homolog 1;
PDBTitle: solution structure of the n-terminal domain of kindlin-1
80c6dkuA_
not modelled 5.0 11
PDB header:unknown function
Chain: A: PDB Molecule:vp35;
PDBTitle: crystal structure of myotis vp35 mutant of interferon inhibitory2 domain

Binding site prediction 

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Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below