1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	D	F	A	P	V	E	L	A	M	F	P	L	E	S	A	P	L	P	D	E	D	L	P	L	H	I	F	E	P	R	Y	A	A	L	V	R	D	C	M	D	T	A	D	P	R	F	G	V	V	L	I	S	R	G	R	E	V	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?													?																																				?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	G	D	T	R	C	D	V	G	T	L	A	R	I	T	E	C	A	D	A	G	S	G	R	Y	M	L	R	C	R	V	G	E	R	I	R	V	C	D	W	L	P	D	D	P	Y	P	R	A	K	V	R	F	W	P	D	Q	P	G	H
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	V	T	A	A	Q	L	L	E	V	E	D	R	V	V	A	L	F	E	R	I	A	A	A	R	G	V	R	L	P	A	R	E	V	V	L	G	Y	P	V	V	D	P	A	D	T	G	Q	R	L	Y	A	L	A	C	R	V	P	M	G
Secondary structure
SS confidence
Disorder		?	?	?	?																				?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.
Sequence		P	A	D	R	Y	A	V	L	A	T	P	S	A	A	D	R	L	V	R	L	G	D	A	L	D	S	V	A	A	M	V	E	F	E	L	S	T
Secondary structure
SS confidence
Disorder																																		?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 20%) Alpha helix ( 38%) Beta strand ( 29%) TM helix ( 7%) (View membrane topology prediction)

Rank Aligned region

PDB 3m65 chain A Region: 4 - 214 Aligned: 202 Modelled: 211 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent protease la 1; PDBTitle: crystal structure of bacillus subtilis lon n-terminal domain Phyre2 PDB 1zbo chain A domain 1 Region: 8 - 205 Aligned: 192 Modelled: 198 Confidence: 100.0% Identity: 24% Fold: PUA domain-like Superfamily: PUA domain-like Family: LON domain-like Phyre2 PDB 3ljc chain A Region: 8 - 214 Aligned: 200 Modelled: 207 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent protease la; PDBTitle: crystal structure of lon n-terminal domain. Phyre2 PDB 2ane chain A domain 1 Region: 8 - 114 Aligned: 107 Modelled: 107 Confidence: 99.9% Identity: 19% Fold: PUA domain-like Superfamily: PUA domain-like Family: LON domain-like Phyre2 PDB 1vco chain A domain 1 Region: 15 - 51 Aligned: 35 Modelled: 37 Confidence: 47.6% Identity: 9% Fold: Flavodoxin-like Superfamily: Class I glutamine amidotransferase-like Family: Class I glutamine amidotransferases (GAT) Phyre2 PDB 3l83 chain A Region: 2 - 51 Aligned: 46 Modelled: 50 Confidence: 45.2% Identity: 24% PDB header:transferase Chain: A: PDB Molecule:glutamine amido transferase; PDBTitle: crystal structure of glutamine amido transferase from methylobacillus2 flagellatus Phyre2 PDB 1vcn chain A Region: 15 - 51 Aligned: 33 Modelled: 37 Confidence: 40.1% Identity: 9% PDB header:ligase Chain: A: PDB Molecule:ctp synthetase; PDBTitle: crystal structure of t.th. hb8 ctp synthetase complex with sulfate2 anion Phyre2 PDB 2w7t chain A Region: 14 - 51 Aligned: 36 Modelled: 38 Confidence: 38.8% Identity: 17% PDB header:ligase Chain: A: PDB Molecule:putative cytidine triphosphate synthase; PDBTitle: trypanosoma brucei ctps - glutaminase domain with bound acivicin Phyre2 PDB 3l7n chain A Region: 2 - 51 Aligned: 48 Modelled: 50 Confidence: 35.3% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of smu.1228c Phyre2 PDB 1ci6 chain B Region: 182 - 212 Aligned: 31 Modelled: 31 Confidence: 31.8% Identity: 16% PDB header:transcription Chain: B: PDB Molecule:transcription factor c/ebp beta; PDBTitle: transcription factor atf4-c/ebp beta bzip heterodimer Phyre2 PDB 2a9v chain A domain 1 Region: 15 - 51 Aligned: 37 Modelled: 37 Confidence: 31.3% Identity: 11% Fold: Flavodoxin-like Superfamily: Class I glutamine amidotransferase-like Family: Class I glutamine amidotransferases (GAT) Phyre2 PDB 1s1m chain A domain 1 Region: 14 - 51 Aligned: 36 Modelled: 38 Confidence: 29.6% Identity: 14% Fold: Flavodoxin-like Superfamily: Class I glutamine amidotransferase-like Family: Class I glutamine amidotransferases (GAT) Phyre2 PDB 2ktl chain A Region: 82 - 106 Aligned: 25 Modelled: 25 Confidence: 24.9% Identity: 8% PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: structure of c-terminal domain from mttyrrs of a. nidulans Phyre2 PDB 2iss chain F Region: 15 - 51 Aligned: 37 Modelled: 37 Confidence: 23.2% Identity: 14% PDB header:lyase, transferase Chain: F: PDB Molecule:glutamine amidotransferase subunit pdxt; PDBTitle: structure of the plp synthase holoenzyme from thermotoga maritima Phyre2 PDB 5ch1 chain B Region: 7 - 39 Aligned: 33 Modelled: 33 Confidence: 22.0% Identity: 27% PDB header:transferase Chain: B: PDB Molecule:putative polycomb protein ezh2,putative polycomb protein PDBTitle: crystal structure of an active polycomb repressive complex 2 in the2 stimulated state Phyre2 PDB 1wl8 chain A domain 1 Region: 15 - 51 Aligned: 35 Modelled: 37 Confidence: 20.8% Identity: 6% Fold: Flavodoxin-like Superfamily: Class I glutamine amidotransferase-like Family: Class I glutamine amidotransferases (GAT) Phyre2 PDB 2nz7 chain A Region: 165 - 206 Aligned: 42 Modelled: 42 Confidence: 20.7% Identity: 21% PDB header:apoptosis Chain: A: PDB Molecule:caspase recruitment domain-containing protein 4; PDBTitle: crystal structure analysis of caspase-recruitment domain2 (card) of nod1 Phyre2 PDB 1jvn chain A domain 2 Region: 5 - 51 Aligned: 47 Modelled: 47 Confidence: 18.9% Identity: 17% Fold: Flavodoxin-like Superfamily: Class I glutamine amidotransferase-like Family: Class I glutamine amidotransferases (GAT) Phyre2 PDB 1p80 chain A domain 1 Region: 2 - 51 Aligned: 50 Modelled: 50 Confidence: 17.5% Identity: 4% Fold: Flavodoxin-like Superfamily: Class I glutamine amidotransferase-like Family: Catalase, C-terminal domain Phyre2 PDB 1k9v chain F Region: 15 - 51 Aligned: 37 Modelled: 37 Confidence: 16.8% Identity: 14% Fold: Flavodoxin-like Superfamily: Class I glutamine amidotransferase-like Family: Class I glutamine amidotransferases (GAT) Phyre2 1 c3m65A_ 2 d1zboa1 3 c3ljcA_ 4 d2anea1 5 d1vcoa1 6 c3l83A_ 7 c1vcnA_ 8 c2w7tA_ 9 c3l7nA_ 10 c1ci6B_ 11 d2a9va1 12 d1s1ma1 13 c2ktlA_ 14 c2issF_ 15 c5ch1B_ 16 d1wl8a1 17 c2nz7A_ 18 d1jvna2 19 d1p80a1 20 d1k9vf_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80