1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	G	K	P	R	G	R	R	G	V	N	L	Q	I	L	P	S	A	M	T	V	L	S	I	C	A	G	L	T	A	I	K	F	A	L	E	H	Q	P	K	A	A	M	A	L	I	A	A	A	A	I	L	D	G	L	D	G	R	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	R	I	L	D	A	Q	S	R	M	G	A	E	I	D	S	L	A	D	A	V	N	F	G	V	T	P	A	L	V	L	Y	V	S	M	L	S	K	W	P	V	G	W	V	V	V	L	L	Y	A	V	C	V	V	L	R	L	A	R	Y
Secondary structure
SS confidence
Disorder					?																																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		N	A	L	Q	D	D	G	T	Q	P	A	Y	A	H	E	F	F	V	G	M	P	A	P	A	G	A	V	S	M	I	G	L	L	A	L	K	M	Q	F	G	E	G	W	W	T	S	G	W	F	L	S	F	W	V	T	G	T	S	I	L
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?	?																												?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	V	S	G	I	P	M	K	K	M	H	A	V	S	V	P	P	N	Y	A	A	A	L	L	A	V	L	A	I	C	A	A	A	A	V	L	A	P	Y	L	L	I	W	V	I	I	I	A	Y	M	C	H	I	P	F	A	V	R	S	Q
Secondary structure
SS confidence
Disorder													?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.
Sequence		R	W	L	A	Q	H	P	E	V	W	D	D	K	P	K	Q	R	R	A	V	R	R	A	S	R	R	A	H	P	Y	R	P	S	M	A	R	L	G	L	R	K	P	G	R	R	L
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?	?	?		?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 25%) Alpha helix ( 67%) Beta strand ( 1%) TM helix ( 52%) (View membrane topology prediction)

Rank Aligned region

PDB 6h59 chain B Region: 5 - 198 Aligned: 188 Modelled: 194 Confidence: 99.9% Identity: 15% PDB header:transferase Chain: B: PDB Molecule:cdp-diacylglycerol--inositol 3-phosphatidyltransferase; PDBTitle: crystal structure of mycobacterium tuberculosis phosphatidylinositol2 phosphate synthase (pgsa1) with cdp-dag bound Phyre2 PDB 5d92 chain B Region: 3 - 185 Aligned: 178 Modelled: 183 Confidence: 99.9% Identity: 17% PDB header:membrane protein Chain: B: PDB Molecule:af2299 protein,phosphatidylinositol synthase; PDBTitle: structure of a phosphatidylinositolphosphate (pip) synthase from2 renibacterium salmoninarum Phyre2 PDB 4o6m chain A Region: 8 - 185 Aligned: 167 Modelled: 178 Confidence: 99.9% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:af2299, a cdp-alcohol phosphotransferase; PDBTitle: structure of af2299, a cdp-alcohol phosphotransferase (cmp-bound) Phyre2 PDB 4mnd chain A Region: 9 - 182 Aligned: 165 Modelled: 174 Confidence: 99.9% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:ctp l-myo-inositol-1-phosphate cytidylyltransferase/cdp-l- PDBTitle: crystal structure of archaeoglobus fulgidus ipct-dipps bifunctional2 membrane protein Phyre2 PDB 2cx6 chain A domain 1 Region: 59 - 82 Aligned: 24 Modelled: 23 Confidence: 32.7% Identity: 17% Fold: Barstar-like Superfamily: Barstar-related Family: Barstar-related Phyre2 PDB 1ay7 chain B Region: 59 - 82 Aligned: 24 Modelled: 24 Confidence: 28.4% Identity: 21% Fold: Barstar-like Superfamily: Barstar-related Family: Barstar-related Phyre2 PDB 4i0x chain J Region: 53 - 82 Aligned: 30 Modelled: 30 Confidence: 21.2% Identity: 17% PDB header:structural genomics, unknown function Chain: J: PDB Molecule:esat-6-like protein mab_3113; PDBTitle: crystal structure of the mycobacterum abscessus esxef (mab_3112-2 mab_3113) complex Phyre2 PDB 2le7 chain A Region: 59 - 72 Aligned: 14 Modelled: 14 Confidence: 11.0% Identity: 64% PDB header:transport protein Chain: A: PDB Molecule:potassium voltage-gated channel subfamily h member 2; PDBTitle: solution nmr structure of the s4s5 linker of herg potassium channel Phyre2 PDB 2kt5 chain B Region: 268 - 282 Aligned: 15 Modelled: 15 Confidence: 10.8% Identity: 40% PDB header:rna binding protein / viral protein Chain: B: PDB Molecule:icp27; PDBTitle: rrm domain of mrna export adaptor ref2-i bound to hsv-1 icp27 peptide Phyre2 PDB 6mjb chain C Region: 62 - 80 Aligned: 19 Modelled: 19 Confidence: 10.0% Identity: 26% PDB header:cell cycle Chain: C: PDB Molecule:kinetochore-associated protein dsn1; PDBTitle: structure of candida glabrata csm1:dsn1(14-72) complex Phyre2 PDB 1w8x chain P Region: 222 - 255 Aligned: 34 Modelled: 34 Confidence: 9.5% Identity: 15% PDB header:virus Chain: P: PDB Molecule:protein p16; PDBTitle: structural analysis of prd1 Phyre2 PDB 3lrc chain C Region: 139 - 247 Aligned: 109 Modelled: 109 Confidence: 8.2% Identity: 15% PDB header:transport protein Chain: C: PDB Molecule:arginine/agmatine antiporter; PDBTitle: structure of e. coli adic (p1) Phyre2 PDB 1gl2 chain D Region: 53 - 76 Aligned: 24 Modelled: 24 Confidence: 6.4% Identity: 29% PDB header:membrane protein Chain: D: PDB Molecule:syntaxin 8; PDBTitle: crystal structure of an endosomal snare core complex Phyre2 PDB 3b5n chain L Region: 53 - 76 Aligned: 24 Modelled: 24 Confidence: 6.0% Identity: 29% PDB header:membrane protein Chain: L: PDB Molecule:protein transport protein sec9; PDBTitle: structure of the yeast plasma membrane snare complex Phyre2 PDB 2ov2 chain O Region: 131 - 148 Aligned: 18 Modelled: 18 Confidence: 5.7% Identity: 17% PDB header:protein binding/transferase Chain: O: PDB Molecule:serine/threonine-protein kinase pak 4; PDBTitle: the crystal structure of the human rac3 in complex with the crib2 domain of human p21-activated kinase 4 (pak4) Phyre2 PDB 6h2e chain P Region: 53 - 82 Aligned: 30 Modelled: 30 Confidence: 5.6% Identity: 23% PDB header:toxin Chain: P: PDB Molecule:ahlc; PDBTitle: structure of the soluble ahlc of the tripartite alpha-pore forming2 toxin, ahl, from aeromonas hydrophila. Phyre2 PDB 1y0k chain A domain 1 Region: 237 - 268 Aligned: 32 Modelled: 32 Confidence: 5.1% Identity: 13% Fold: Restriction endonuclease-like Superfamily: Restriction endonuclease-like Family: PA4535-like Phyre2 PDB 2amw chain A Region: 55 - 78 Aligned: 24 Modelled: 24 Confidence: 5.1% Identity: 29% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ne2163; PDBTitle: solution nmr structure of protein ne2163 from nitrosomonas europaea.2 northeast structural genomics consortium target net1. Phyre2 1 c6h59B_ 2 c5d92B_ 3 c4o6mA_ 4 c4mndA_ 5 d2cx6a1 6 d1ay7b_ 7 c4i0xJ_ 8 c2le7A_ 9 c2kt5B_ 10 c6mjbC_ 11 c1w8xP_ 12 c3lrcC_ 13 c1gl2D_ 14 c3b5nL_ 15 c2ov2O_ 16 c6h2eP_ 17 d1y0ka1 18 c2amwA_