Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD0450c_(mmpL4)_538591_541494
DateTue Jul 23 14:50:52 BST 2019
Unique Job ID48df5759b807b22c
SequenceVSTKFANDSN ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:64.666 Y:91.183 Z:101.915
Model (left) based on template c6ajjA_
Top template information
PDB header:membrane protein, hydrolase
Chain: A: PDB Molecule:drug exporters of the rnd superfamily-like protein,
PDBTitle: crystal structure of mycolic acid transporter mmpl3 from mycobacterium2 smegmatis complexed with ica38
Confidence and coverage
Confidence:100.0% Coverage: 73%
709 residues ( 73% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
939 residues ( 97%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c6ajjA_
100.0 19
PDB header:membrane protein, hydrolase
Chain: A: PDB Molecule:drug exporters of the rnd superfamily-like protein,
PDBTitle: crystal structure of mycolic acid transporter mmpl3 from mycobacterium2 smegmatis complexed with ica38
2c5lq3F_
100.0 14
PDB header:transport protein
Chain: F: PDB Molecule:cmeb;
PDBTitle: structures and transport dynamics of the campylobacter jejuni2 multidrug efflux pump cmeb
3c3k07A_
100.0 14
PDB header:transport protein
Chain: A: PDB Molecule:cation efflux system protein cusa;
PDBTitle: crystal structure of cusa
4c6owsB_
100.0 12
PDB header:membrane protein
Chain: B: PDB Molecule:efflux pump membrane transporter;
PDBTitle: cryo-em structure of an acinetobacter baumannii multidrug efflux pump
5c4mt1A_
100.0 12
PDB header:membrane protein, tranport protein
Chain: A: PDB Molecule:drug efflux protein;
PDBTitle: crystal structure of the neisseria gonorrhoeae mtrd inner membrane2 multidrug efflux pump
6c2v50A_
100.0 14
PDB header:membrane protein
Chain: A: PDB Molecule:multidrug resistance protein mexb;
PDBTitle: the missing part of the bacterial mexab-oprm system: structural2 determination of the multidrug exporter mexb
7c4k0eA_
100.0 14
PDB header:transport protein
Chain: A: PDB Molecule:heavy metal cation tricomponent efflux pump znea(czca-
PDBTitle: x-ray crystal structure of a heavy metal efflux pump, crystal form ii
8c1oy8A_
100.0 13
PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
9c6dmoA_
100.0 13
PDB header:protein binding
Chain: A: PDB Molecule:protein patched homolog 1;
PDBTitle: cryo-em structure of human ptch1 with three mutations2 l282q/t500f/p504l
10c5khnB_
100.0 17
PDB header:membrane protein
Chain: B: PDB Molecule:rnd transporter;
PDBTitle: crystal structures of the burkholderia multivorans hopanoid2 transporter hpnn
11c4k0eC_
100.0 14
PDB header:transport protein
Chain: C: PDB Molecule:heavy metal cation tricomponent efflux pump znea(czca-
PDBTitle: x-ray crystal structure of a heavy metal efflux pump, crystal form ii
12c6csxA_
100.0 13
PDB header:transport protein
Chain: A: PDB Molecule:multidrug efflux pump subunit acrb;
PDBTitle: single particles cryo-em structure of acrb d407a associated with lipid2 bilayer at 3.0 angstrom
13c3jd8A_
100.0 15
PDB header:membrane protein
Chain: A: PDB Molecule:niemann-pick c1 protein;
PDBTitle: cryo-em structure of the full-length human npc1 at 4.4 angstrom
14c3aqpB_
100.0 16
PDB header:membrane protein
Chain: B: PDB Molecule:probable secdf protein-export membrane protein;
PDBTitle: crystal structure of secdf, a translocon-associated membrane protein,2 from thermus thrmophilus
15c5xamA_
100.0 14
PDB header:membrane protein
Chain: A: PDB Molecule:protein translocase subunit secd;
PDBTitle: crystal structure of secdf in i form at 4 a resolution
16c5mg3D_
100.0 14
PDB header:chaperone
Chain: D: PDB Molecule:protein translocase subunit secd;
PDBTitle: em fitted model of bacterial holo-translocon
17c5mg3F_
99.9 12
PDB header:chaperone
Chain: F: PDB Molecule:protein translocase subunit secf;
PDBTitle: em fitted model of bacterial holo-translocon
18d1iwga8
99.9 12
Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
19d1iwga7
99.9 17
Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
20c5ensA_
99.6 9
PDB header:transport protein
Chain: A: PDB Molecule:multidrug efflux pump subunit acrb,multidrug efflux pump
PDBTitle: rhodamine bound structure of bacterial efflux pump.
21c4r86B_
not modelled 98.8 9
PDB header:protein transport
Chain: B: PDB Molecule:rnd family aminoglycoside/multidrug efflux pump;
PDBTitle: crystal structure of aminoglycoside/multidrug efflux system acrd from2 salmonella typhimurium
22d1iwga6
not modelled 92.3 9
Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
23d1iwga3
not modelled 90.6 8
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
24c2yvxD_
not modelled 78.5 10
PDB header:transport protein
Chain: D: PDB Molecule:mg2+ transporter mgte;
PDBTitle: crystal structure of magnesium transporter mgte
25d1iwga2
not modelled 67.2 14
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
26c4av3A_
not modelled 67.1 16
PDB header:hydrolase
Chain: A: PDB Molecule:k(+)-stimulated pyrophosphate-energized sodium pump;
PDBTitle: crystal structure of thermotoga maritima sodium pumping membrane2 integral pyrophosphatase with metal ions in active site
27d1iwga4
not modelled 62.3 6
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
28c2mkvA_
not modelled 42.3 28
PDB header:transport protein
Chain: A: PDB Molecule:sodium/potassium-transporting atpase subunit gamma;
PDBTitle: structure of the na,k-atpase regulatory protein fxyd2b in micelles
29c1p58E_
not modelled 39.9 14
PDB header:virus
Chain: E: PDB Molecule:envelope protein m;
PDBTitle: complex organization of dengue virus membrane proteins as revealed by2 9.5 angstrom cryo-em reconstruction
30c4ky0B_
not modelled 25.8 11
PDB header:transport protein, membrane protein
Chain: B: PDB Molecule:proton/glutamate symporter, sdf family;
PDBTitle: crystal structure of a substrate-free glutamate transporter homologue2 from thermococcus kodakarensis
31c5zlgA_
not modelled 24.8 13
PDB header:oxidoreductase
Chain: A: PDB Molecule:cytochrome b reductase 1;
PDBTitle: human duodenal cytochrome b (dcytb) in zinc ion and ascorbate bound2 form
32c1ciiA_
not modelled 20.4 14
PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia
33c2m1hA_
not modelled 20.0 17
PDB header:transcription
Chain: A: PDB Molecule:transcription elongation factor s-ii;
PDBTitle: solution structure of a pwwp domain from trypanosoma brucei
34d1iwga5
not modelled 19.7 7
Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
35c2mk9A_
not modelled 19.3 29
PDB header:immune system
Chain: A: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the dimeric transmembrane domain of toll-like2 receptor 3
36c2mkaA_
not modelled 19.3 29
PDB header:immune system
Chain: A: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
37c2mk9B_
not modelled 19.3 29
PDB header:immune system
Chain: B: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the dimeric transmembrane domain of toll-like2 receptor 3
38c2mkaC_
not modelled 19.3 29
PDB header:immune system
Chain: C: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
39c2mkaB_
not modelled 19.3 29
PDB header:immune system
Chain: B: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
40c6bqiA_
not modelled 18.0 15
PDB header:translation
Chain: A: PDB Molecule:protein impact homolog;
PDBTitle: structure of two-domain translational regulator yih1 reveals a2 possible mechanism of action
41c2kseA_
not modelled 17.6 29
PDB header:transferase
Chain: A: PDB Molecule:sensor protein qsec;
PDBTitle: backbone structure of the membrane domain of e. coli histidine kinase2 receptor qsec, center for structures of membrane proteins (csmp)3 target 4311c
42c2qg8A_
not modelled 15.8 22
PDB header:transferase
Chain: A: PDB Molecule:acyl carrier protein synthase py06285;
PDBTitle: plasmodium yoelii acyl carrier protein synthase py06285 with adp bound
43c6o7ua_
not modelled 15.2 15
PDB header:membrane protein
Chain: A: PDB Molecule:
PDBTitle: saccharomyces cerevisiae v-atpase stv1-vo
44c1a87A_
not modelled 14.4 13
PDB header:bacteriocin
Chain: A: PDB Molecule:colicin n;
PDBTitle: colicin n
45d1a87a_
not modelled 14.4 13
Fold:Toxins' membrane translocation domains
Superfamily:Colicin
Family:Colicin
46c6gctA_
not modelled 13.7 12
PDB header:membrane protein
Chain: A: PDB Molecule:neutral amino acid transporter b(0);
PDBTitle: cryo-em structure of the human neutral amino acid transporter asct2
47c6b2zf_
not modelled 13.4 18
PDB header:membrane protein
Chain: F: PDB Molecule:atp synthase subunit c, mitochondrial;
PDBTitle: cryo-em structure of the dimeric fo region of yeast mitochondrial atp2 synthase
48c2bbjB_
not modelled 13.3 18
PDB header:metal transport/membrane protein
Chain: B: PDB Molecule:divalent cation transport-related protein;
PDBTitle: crystal structure of the cora mg2+ transporter
49c2k1kA_
not modelled 13.3 16
PDB header:signaling protein
Chain: A: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 4.3
50c2k1lA_
not modelled 13.3 16
PDB header:signaling protein
Chain: A: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 6.3
51c2k1kB_
not modelled 13.3 16
PDB header:signaling protein
Chain: B: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 4.3
52c2k1lB_
not modelled 13.3 16
PDB header:signaling protein
Chain: B: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 6.3
53d1kf6d_
not modelled 13.1 8
Fold:Heme-binding four-helical bundle
Superfamily:Fumarate reductase respiratory complex transmembrane subunits
Family:Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD)
54c6b8ht_
not modelled 12.7 18
PDB header:membrane protein
Chain: T: PDB Molecule:atp synthase subunit 9, mitochondrial;
PDBTitle: mosaic model of yeast mitochondrial atp synthase monomer
55c6fkip_
not modelled 12.7 10
PDB header:membrane protein
Chain: P: PDB Molecule:atp synthase subunit c, chloroplastic;
PDBTitle: chloroplast f1fo conformation 3
56c2kncB_
not modelled 11.5 14
PDB header:cell adhesion
Chain: B: PDB Molecule:integrin beta-3;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex
57c5kk2E_
not modelled 11.1 17
PDB header:membrane protein, transport protein, sig
Chain: E: PDB Molecule:voltage-dependent calcium channel gamma-2 subunit;
PDBTitle: architecture of fully occupied glua2 ampa receptor - tarp complex2 elucidated by single particle cryo-electron microscopy
58c2lgxA_
not modelled 11.0 29
PDB header:cell adhesion
Chain: A: PDB Molecule:fermitin family homolog 2;
PDBTitle: nmr structure for kindle-2 n-terminus
59c1p58F_
not modelled 10.9 17
PDB header:virus
Chain: F: PDB Molecule:envelope protein m;
PDBTitle: complex organization of dengue virus membrane proteins as revealed by2 9.5 angstrom cryo-em reconstruction
60c3w66A_
not modelled 10.6 7
PDB header:metal transport
Chain: A: PDB Molecule:magnetosome protein mamm;
PDBTitle: mamm-ctd d249a and h285a
61d2nwwa1
not modelled 10.3 7
Fold:Proton glutamate symport protein
Superfamily:Proton glutamate symport protein
Family:Proton glutamate symport protein
62c3hqjA_
not modelled 10.2 12
PDB header:transferase
Chain: A: PDB Molecule:holo-[acyl-carrier-protein] synthase;
PDBTitle: structure-function analysis of mycobacterium tuberculosis2 acyl carrier protein synthase (acps).
63c2ww9B_
not modelled 10.2 12
PDB header:ribosome
Chain: B: PDB Molecule:protein transport protein sss1;
PDBTitle: cryo-em structure of the active yeast ssh1 complex bound to the yeast2 80s ribosome
64c4cbfB_
not modelled 10.0 14
PDB header:virus
Chain: B: PDB Molecule:m protein;
PDBTitle: near-atomic resolution cryo-em structure of dengue serotype 4 virus
65c2kmcA_
not modelled 9.9 29
PDB header:cell adhesion
Chain: A: PDB Molecule:fermitin family homolog 1;
PDBTitle: solution structure of the n-terminal domain of kindlin-1
66d1f7la_
not modelled 9.7 15
Fold:4'-phosphopantetheinyl transferase
Superfamily:4'-phosphopantetheinyl transferase
Family:Holo-(acyl carrier protein) synthase ACPS
67c6fkib_
not modelled 9.7 13
PDB header:membrane protein
Chain: B: PDB Molecule:atp synthase subunit beta, chloroplastic;
PDBTitle: chloroplast f1fo conformation 3
68c2jp3A_
not modelled 9.5 18
PDB header:transcription
Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4;
PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles
69c4y0lA_
not modelled 9.5 14
PDB header:membrane protein
Chain: A: PDB Molecule:putative membrane protein mmpl11;
PDBTitle: mycobacterial membrane protein mmpl11d2
70c2jbzA_
not modelled 9.5 19
PDB header:transferase
Chain: A: PDB Molecule:holo-[acyl-carrier-protein] synthase;
PDBTitle: crystal structure of the streptomyces coelicolor holo-2 [acyl-carrier-protein] synthase (acps) in complex with3 coenzyme a at 1.6 a
71c4cdiC_
not modelled 9.1 26
PDB header:membrane protein
Chain: C: PDB Molecule:predicted protein;
PDBTitle: crystal structure of acrb-acrz complex
72c4fe1I_
not modelled 9.0 19
PDB header:photosynthesis
Chain: I: PDB Molecule:photosystem i reaction center subunit viii;
PDBTitle: improving the accuracy of macromolecular structure refinement at 7 a2 resolution
73d1jb0i_
not modelled 9.0 19
Fold:Single transmembrane helix
Superfamily:Subunit VIII of photosystem I reaction centre, PsaI
Family:Subunit VIII of photosystem I reaction centre, PsaI
74c4gn0D_
not modelled 8.9 10
PDB header:signaling protein
Chain: D: PDB Molecule:hamp domain of af1503;
PDBTitle: de novo phasing of a hamp-complex using an improved arcimboldo method
75c4a2nB_
not modelled 8.8 9
PDB header:transferase
Chain: B: PDB Molecule:isoprenylcysteine carboxyl methyltransferase;
PDBTitle: crystal structure of ma-icmt
76c4or2A_
not modelled 8.8 13
PDB header:signaling protein
Chain: A: PDB Molecule:soluble cytochrome b562, metabotropic glutamate receptor 1;
PDBTitle: human class c g protein-coupled metabotropic glutamate receptor 1 in2 complex with a negative allosteric modulator
77c6dkuA_
not modelled 8.6 11
PDB header:unknown function
Chain: A: PDB Molecule:vp35;
PDBTitle: crystal structure of myotis vp35 mutant of interferon inhibitory2 domain
78c5n9yB_
not modelled 8.5 15
PDB header:membrane protein
Chain: B: PDB Molecule:zinc transport protein zntb;
PDBTitle: the full-length structure of zntb
79c4a01B_
not modelled 8.2 11
PDB header:hydrolase
Chain: B: PDB Molecule:proton pyrophosphatase;
PDBTitle: crystal structure of the h-translocating pyrophosphatase
80c3v7oA_
not modelled 8.2 19
PDB header:transcription
Chain: A: PDB Molecule:minor nucleoprotein vp30;
PDBTitle: crystal structure of the c-terminal domain of ebola virus vp30 (strain2 reston-89)
81c2qfiB_
not modelled 7.7 12
PDB header:transport protein
Chain: B: PDB Molecule:ferrous-iron efflux pump fief;
PDBTitle: structure of the zinc transporter yiip
82d2qfia1
not modelled 7.6 12
Fold:Alpha-lytic protease prodomain-like
Superfamily:Cation efflux protein cytoplasmic domain-like
Family:Cation efflux protein cytoplasmic domain-like
83d2yvxa3
not modelled 7.5 8
Fold:MgtE membrane domain-like
Superfamily:MgtE membrane domain-like
Family:MgtE membrane domain-like
84c4dh4A_
not modelled 7.4 10
PDB header:isomerase
Chain: A: PDB Molecule:mif;
PDBTitle: macrophage migration inhibitory factor toxoplasma gondii
85c5cmoB_
not modelled 7.4 24
PDB header:transferase
Chain: B: PDB Molecule:holo-[acyl-carrier-protein] synthase;
PDBTitle: crystal structure of holo-[acyl-carrier-protein] synthase (acps) from2 neisseria meningitidis
86c5ho5D_
not modelled 7.4 20
PDB header:metal transport
Chain: D: PDB Molecule:magnetosome protein mamb;
PDBTitle: mamb
87c5gasN_
not modelled 7.3 7
PDB header:hydrolase
Chain: N: PDB Molecule:archaeal/vacuolar-type h+-atpase subunit i;
PDBTitle: thermus thermophilus v/a-atpase, conformation 2
88d1j3wa_
not modelled 7.3 12
Fold:Profilin-like
Superfamily:Roadblock/LC7 domain
Family:Roadblock/LC7 domain
89c3tufA_
not modelled 7.0 8
PDB header:signaling protein
Chain: A: PDB Molecule:stage iii sporulation protein ah;
PDBTitle: structure of the spoiiq-spoiiiah pore forming complex.
90d1hfoa_
not modelled 6.9 10
Fold:Tautomerase/MIF
Superfamily:Tautomerase/MIF
Family:MIF-related
91c2xczA_
not modelled 6.8 16
PDB header:immune system
Chain: A: PDB Molecule:possible atls1-like light-inducible protein;
PDBTitle: crystal structure of macrophage migration inhibitory factor homologue2 from prochlorococcus marinus
92c2lowA_
not modelled 6.8 33
PDB header:membrane protein
Chain: A: PDB Molecule:apelin receptor;
PDBTitle: solution structure of ar55 in 50% hfip
93c5f1bC_
not modelled 6.8 11
PDB header:viral protein/transport protein
Chain: C: PDB Molecule:niemann-pick c1 protein;
PDBTitle: structural basis of ebola virus entry: viral glycoprotein bound to its2 endosomal receptor niemann-pick c1
94d1qmga1
not modelled 6.8 19
Fold:6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like
Family:Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)
95d1sd4a_
not modelled 6.8 7
Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Penicillinase repressor
96d3bzka3
not modelled 6.7 14
Fold:Tex N-terminal region-like
Superfamily:Tex N-terminal region-like
Family:Tex N-terminal region-like
97d1kkga_
not modelled 6.6 16
Fold:Alpha-lytic protease prodomain-like
Superfamily:Ribosome-binding factor A, RbfA
Family:Ribosome-binding factor A, RbfA
98d2cwqa1
not modelled 6.6 14
Fold:AhpD-like
Superfamily:AhpD-like
Family:TTHA0727-like
99c3h88A_
not modelled 6.6 37
PDB header:transferase
Chain: A: PDB Molecule:holo-[acyl-carrier-protein] synthase;
PDBTitle: crystal structure of 4'-phosphopantetheinyl transferase acps from2 vibrio cholerae o1 biovar eltor

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Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below