1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	R	L	S	S	I	L	R	A	G	A	A	F	L	V	L	G	I	A	A	A	T	F	P	Q	S	A	A	A	D	S	T	E	D	F	P	I	P	R	R	M	I	A	T	T	C	D	A	E	Q	Y	L	A	A	V	R	D	T	S
Secondary structure
SS confidence
Disorder		?	?																				?	?	?	?	?	?	?		?	?	?	?	?						?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	V	Y	Y	Q	R	Y	M	I	D	F	N	N	H	A	N	L	Q	Q	A	T	I	N	K	A	H	W	F	F	S	L	S	P	A	E	R	R	D	Y	S	E	H	F	Y	N	G	D	P	L	T	F	A	W	V	N	H	M	K	I	F
Secondary structure
SS confidence
Disorder																																				?	?				?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.
Sequence		F	N	N	K	G	V	V	A	K	G	T	E	V	C	N	G	Y	P	A	G	D	M	S	V	W	N	W	A
Secondary structure
SS confidence
Disorder										?					?									?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 20%) Alpha helix ( 45%) Beta strand ( 26%)

Rank Aligned region

PDB 4oo2 chain D Region: 49 - 85 Aligned: 37 Modelled: 34 Confidence: 28.4% Identity: 27% PDB header:oxidoreductase Chain: D: PDB Molecule:chlorophenol-4-monooxygenase; PDBTitle: streptomyces globisporus c-1027 fad dependent (s)-3-chloro-β-2 tyrosine-s-sgcc2 c-5 hydroxylase sgcc apo form Phyre2 PDB 1r8j chain B Region: 62 - 101 Aligned: 24 Modelled: 24 Confidence: 19.3% Identity: 25% PDB header:circadian clock protein Chain: B: PDB Molecule:kaia; PDBTitle: crystal structure of circadian clock protein kaia from2 synechococcus elongatus Phyre2 PDB 4h9k chain A Region: 61 - 68 Aligned: 8 Modelled: 8 Confidence: 15.3% Identity: 75% PDB header:hydrolase Chain: A: PDB Molecule:hog cholera virus; PDBTitle: crystal structure of cleavage site mutant of npro of classical swine2 fever virus. Phyre2 PDB 3hwc chain D Region: 49 - 81 Aligned: 33 Modelled: 33 Confidence: 15.1% Identity: 21% PDB header:oxidoreductase Chain: D: PDB Molecule:chlorophenol-4-monooxygenase component 2; PDBTitle: crystal structure of chlorophenol 4-monooxygenase (tftd) of2 burkholderia cepacia ac1100 Phyre2 PDB 6eb0 chain A Region: 49 - 85 Aligned: 37 Modelled: 37 Confidence: 14.9% Identity: 24% PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit; PDBTitle: structure of 4-hydroxyphenylacetate 3-monooxygenase (hpab), oxygenase2 component from escherichia coli Phyre2 PDB 1eq8 chain C Region: 1 - 17 Aligned: 17 Modelled: 17 Confidence: 11.3% Identity: 53% PDB header:signaling protein Chain: C: PDB Molecule:acetylcholine receptor protein; PDBTitle: three-dimensional structure of the pentameric helical2 bundle of the acetylcholine receptor m2 transmembrane3 segment Phyre2 PDB 1eq8 chain A Region: 1 - 17 Aligned: 17 Modelled: 17 Confidence: 11.3% Identity: 53% PDB header:signaling protein Chain: A: PDB Molecule:acetylcholine receptor protein; PDBTitle: three-dimensional structure of the pentameric helical2 bundle of the acetylcholine receptor m2 transmembrane3 segment Phyre2 PDB 1eq8 chain E Region: 1 - 17 Aligned: 17 Modelled: 17 Confidence: 11.3% Identity: 53% PDB header:signaling protein Chain: E: PDB Molecule:acetylcholine receptor protein; PDBTitle: three-dimensional structure of the pentameric helical2 bundle of the acetylcholine receptor m2 transmembrane3 segment Phyre2 PDB 1eq8 chain B Region: 1 - 17 Aligned: 17 Modelled: 17 Confidence: 11.3% Identity: 53% PDB header:signaling protein Chain: B: PDB Molecule:acetylcholine receptor protein; PDBTitle: three-dimensional structure of the pentameric helical2 bundle of the acetylcholine receptor m2 transmembrane3 segment Phyre2 PDB 1eq8 chain D Region: 1 - 17 Aligned: 17 Modelled: 17 Confidence: 11.3% Identity: 53% PDB header:signaling protein Chain: D: PDB Molecule:acetylcholine receptor protein; PDBTitle: three-dimensional structure of the pentameric helical2 bundle of the acetylcholine receptor m2 transmembrane3 segment Phyre2 PDB 1a11 chain A Region: 1 - 17 Aligned: 17 Modelled: 17 Confidence: 11.1% Identity: 53% PDB header:acetylcholine receptor Chain: A: PDB Molecule:acetylcholine receptor m2; PDBTitle: nmr structure of membrane spanning segment 2 of the2 acetylcholine receptor in dpc micelles, 10 structures Phyre2 PDB 4rv2 chain A Region: 36 - 65 Aligned: 30 Modelled: 30 Confidence: 10.9% Identity: 10% PDB header:lyase Chain: A: PDB Molecule:upf0336 protein msmeg_1340/msmei_1302; PDBTitle: crystal structure of (3r)-hydroxyacyl-acp dehydratase hadab hetero-2 dimer from mycobacterium smegmatis Phyre2 PDB 5n6y chain C Region: 122 - 138 Aligned: 17 Modelled: 17 Confidence: 10.3% Identity: 24% PDB header:oxidoreductase Chain: C: PDB Molecule:nitrogenase vanadium-iron protein delta chain; PDBTitle: azotobacter vinelandii vanadium nitrogenase Phyre2 PDB 1fi6 chain A Region: 89 - 108 Aligned: 20 Modelled: 20 Confidence: 9.9% Identity: 20% Fold: EF Hand-like Superfamily: EF-hand Family: Eps15 homology domain (EH domain) Phyre2 PDB 2ghv chain C domain 1 Region: 47 - 69 Aligned: 23 Modelled: 23 Confidence: 9.1% Identity: 22% Fold: SARS receptor-binding domain-like Superfamily: SARS receptor-binding domain-like Family: SARS receptor-binding domain-like Phyre2 PDB 3p4h chain A Region: 90 - 146 Aligned: 41 Modelled: 57 Confidence: 8.9% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent dna ligase, n-terminal domain protein; PDBTitle: structures of archaeal members of the ligd 3'-phosphoesterase dna2 repair enzyme superfamily Phyre2 PDB 1l5i chain A Region: 67 - 112 Aligned: 34 Modelled: 46 Confidence: 8.2% Identity: 29% Fold: Origin of replication-binding domain, RBD-like Superfamily: Origin of replication-binding domain, RBD-like Family: DNA-binding domain of REP protein Phyre2 PDB 1ii0 chain A Region: 119 - 135 Aligned: 17 Modelled: 17 Confidence: 8.1% Identity: 35% PDB header:hydrolase Chain: A: PDB Molecule:arsenical pump-driving atpase; PDBTitle: crystal structure of the escherichia coli arsenite-translocating2 atpase Phyre2 PDB 1rh2 chain A Region: 7 - 59 Aligned: 52 Modelled: 53 Confidence: 7.5% Identity: 13% Fold: 4-helical cytokines Superfamily: 4-helical cytokines Family: Interferons/interleukin-10 (IL-10) Phyre2 PDB 5l0l chain B Region: 83 - 99 Aligned: 17 Modelled: 17 Confidence: 7.5% Identity: 41% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein lpg0439 Phyre2 1 c4oo2D_ 2 c1r8jB_ 3 c4h9kA_ 4 c3hwcD_ 5 c6eb0A_ 6 c1eq8C_ 7 c1eq8A_ 8 c1eq8E_ 9 c1eq8B_ 10 c1eq8D_ 11 c1a11A_ 12 c4rv2A_ 13 c5n6yC_ 14 d1fi6a_ 15 d2ghvc1 16 c3p4hA_ 17 d1l5ia_ 18 c1ii0A_ 19 d1rh2a_ 20 c5l0lB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43