1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	A	P	A	G	V	L	I	T	A	E	A	A	A	L	L	A	G	L	Q	D	R	H	G	P	V	M	F	H	Q	S	G	G	C	C	D	G	S	A	P	M	C	Y	P	R	A	D	F	L	V	G	D	R	D	I	L	L	G	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																							?	?	?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	D	V	G	E	D	G	V	P	V	W	I	S	G	P	Q	Y	Q	A	W	K	H	T	Q	L	I	I	D	V	V	P	G	R	G	G	G	F	S	L	E	A	P	E	G	V	R	F	L	S	R	G	R	V	F	S	D	A	E	K	A
Secondary structure
SS confidence
Disorder																																?	?		?	?		?	?	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.
Sequence		M	R	E	A	A	P	V	I	T	G	A	A	Y	E	C	G	E	R	P	L	V	R	G	L	V	V	D	L	D	D	P	D	A	T	P	G	V	C	R	A	S	R	R
Secondary structure
SS confidence
Disorder					?												?																					?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 19%) Alpha helix ( 22%) Beta strand ( 34%)

Rank Aligned region

PDB 2apn chain A Region: 2 - 102 Aligned: 91 Modelled: 101 Confidence: 98.3% Identity: 20% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:protein hi1723; PDBTitle: hi1723 solution structure Phyre2 PDB 1s98 chain A Region: 7 - 102 Aligned: 86 Modelled: 96 Confidence: 97.7% Identity: 22% Fold: HesB-like domain Superfamily: HesB-like domain Family: HesB-like domain Phyre2 PDB 2d2a chain A Region: 7 - 105 Aligned: 89 Modelled: 99 Confidence: 97.5% Identity: 17% PDB header:metal transport Chain: A: PDB Molecule:sufa protein; PDBTitle: crystal structure of escherichia coli sufa involved in biosynthesis of2 iron-sulfur clusters Phyre2 PDB 1nwb chain A Region: 7 - 102 Aligned: 87 Modelled: 96 Confidence: 97.3% Identity: 25% Fold: HesB-like domain Superfamily: HesB-like domain Family: HesB-like domain Phyre2 PDB 1x0g chain A Region: 7 - 107 Aligned: 88 Modelled: 101 Confidence: 96.4% Identity: 20% PDB header:metal binding protein Chain: A: PDB Molecule:isca; PDBTitle: crystal structure of isca with the [2fe-2s] cluster Phyre2 PDB 2k4z chain A Region: 2 - 107 Aligned: 97 Modelled: 106 Confidence: 95.5% Identity: 16% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:dsrr; PDBTitle: solution nmr structure of allochromatium vinosum dsrr:2 northeast structural genomics consortium target op5 Phyre2 PDB 2qgo chain A Region: 7 - 104 Aligned: 88 Modelled: 98 Confidence: 89.5% Identity: 17% PDB header:biosynthetic protein Chain: A: PDB Molecule:putative fe-s biosynthesis protein; PDBTitle: crystal structure of a putative fe-s biosynthesis protein from2 lactobacillus acidophilus Phyre2 PDB 2p2e chain A domain 1 Region: 7 - 94 Aligned: 82 Modelled: 88 Confidence: 84.2% Identity: 17% Fold: HesB-like domain Superfamily: HesB-like domain Family: HesB-like domain Phyre2 PDB 6imn chain B Region: 85 - 122 Aligned: 38 Modelled: 38 Confidence: 52.0% Identity: 24% PDB header:ligase/dna Chain: B: PDB Molecule:dna ligase; PDBTitle: the crystal structure of asfvlig:ct2 complex Phyre2 PDB 6hqz chain B Region: 14 - 29 Aligned: 16 Modelled: 16 Confidence: 44.6% Identity: 56% PDB header:hydrolase Chain: B: PDB Molecule:avrrpt2; PDBTitle: crystal structure of the type iii effector protein avrrpt2 from2 erwinia amylovora, a c70 family cysteine protease Phyre2 PDB 1umy chain A Region: 33 - 41 Aligned: 8 Modelled: 9 Confidence: 41.4% Identity: 75% Fold: TIM beta/alpha-barrel Superfamily: Homocysteine S-methyltransferase Family: Homocysteine S-methyltransferase Phyre2 PDB 4ccz chain A Region: 33 - 41 Aligned: 8 Modelled: 8 Confidence: 38.6% Identity: 88% PDB header:transferase Chain: A: PDB Molecule:methionine synthase; PDBTitle: crystal structure of human 5-methyltetrahydrofolate-homocysteine2 methyltransferase, the homocysteine and folate binding domains Phyre2 PDB 3bof chain A domain 2 Region: 33 - 41 Aligned: 8 Modelled: 9 Confidence: 38.6% Identity: 75% Fold: TIM beta/alpha-barrel Superfamily: Homocysteine S-methyltransferase Family: Homocysteine S-methyltransferase Phyre2 PDB 1lt7 chain A Region: 33 - 41 Aligned: 8 Modelled: 9 Confidence: 36.9% Identity: 75% Fold: TIM beta/alpha-barrel Superfamily: Homocysteine S-methyltransferase Family: Homocysteine S-methyltransferase Phyre2 PDB 3bol chain B Region: 33 - 41 Aligned: 8 Modelled: 8 Confidence: 32.9% Identity: 75% PDB header:transferase Chain: B: PDB Molecule:5-methyltetrahydrofolate s-homocysteine PDBTitle: cobalamin-dependent methionine synthase (1-566) from2 thermotoga maritima complexed with zn2+ Phyre2 PDB 1pjc chain A Region: 53 - 102 Aligned: 50 Modelled: 50 Confidence: 32.4% Identity: 22% PDB header:oxidoreductase Chain: A: PDB Molecule:protein (l-alanine dehydrogenase); PDBTitle: l-alanine dehydrogenase complexed with nad Phyre2 PDB 2ab9 chain A Region: 34 - 47 Aligned: 14 Modelled: 14 Confidence: 32.2% Identity: 43% PDB header:hydrolase inhibitor Chain: A: PDB Molecule:pro-sfti-1; PDBTitle: discovery, structural determination and processing of the2 precursor protein that produces the cyclic trypsin3 inhibitor sfti-1 Phyre2 PDB 6hpf chain A Region: 3 - 31 Aligned: 29 Modelled: 29 Confidence: 28.5% Identity: 28% PDB header:hydrolase Chain: A: PDB Molecule:endo-b-mannanase; PDBTitle: structure of inactive e165q mutant of fungal non-cbm carrying gh262 endo-b-mannanase from yunnania penicillata in complex with alpha-62-3 61-di-galactosyl-mannotriose Phyre2 PDB 2wbr chain A Region: 17 - 30 Aligned: 14 Modelled: 14 Confidence: 27.4% Identity: 50% PDB header:dna-binding protein Chain: A: PDB Molecule:gw182; PDBTitle: the rrm domain in gw182 proteins contributes to mirna-2 mediated gene silencing Phyre2 PDB 2iht chain A domain 1 Region: 10 - 129 Aligned: 107 Modelled: 120 Confidence: 25.8% Identity: 15% Fold: DHS-like NAD/FAD-binding domain Superfamily: DHS-like NAD/FAD-binding domain Family: Pyruvate oxidase and decarboxylase, middle domain Phyre2 1 c2apnA_ 2 d1s98a_ 3 c2d2aA_ 4 d1nwba_ 5 c1x0gA_ 6 c2k4zA_ 7 c2qgoA_ 8 d2p2ea1 9 c6imnB_ 10 c6hqzB_ 11 d1umya_ 12 c4cczA_ 13 d3bofa2 14 d1lt7a_ 15 c3bolB_ 16 c1pjcA_ 17 c2ab9A_ 18 c6hpfA_ 19 c2wbrA_ 20 d2ihta1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99