1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	D	A	G	A	G	S	R	L	R	S	W	A	Y	A	L	R	T	T	N	P	P	A	D	G	P	T	D	T	V	T	R	W	L	V	V	T	R	A	A	V	L	P	M	T	L	V	S	G	L	V	A	G	L	L	A	I	G	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?													?		?	?	?		?													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	G	L	D	W	R	W	L	V	L	W	W	E	S	H	A	P	H	I	A	N	N	L	M	N	D	L	Y	D	T	D	V	G	T	D	S	A	T	Y	A	R	A	R	Y	A	Q	H	P	A	A	T	G	A	N	R	A	A	Y	T	T
Secondary structure
SS confidence
Disorder																																																												?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.
Sequence		P	R	R	T	T	S	C	G	S	P	E	R	A	L	E	P	T	T	P	R	W	A	R	A	V	G	R	S	C	W	R	R	S	P	T	G	C	C	A	P	R	C
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?			?	?	?																			?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 23%) Alpha helix ( 66%) Beta strand ( 0%) TM helix ( 20%) (View membrane topology prediction)

Rank Aligned region

PDB 4od5 chain C Region: 38 - 113 Aligned: 69 Modelled: 76 Confidence: 97.9% Identity: 22% PDB header:transferase Chain: C: PDB Molecule:4-hydroxybenzoate octaprenyltransferase; PDBTitle: substrate-bound structure of a ubia homolog from aeropyrum pernix k1 Phyre2 PDB 3llw chain A Region: 30 - 96 Aligned: 63 Modelled: 67 Confidence: 38.5% Identity: 11% PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase (ispa); PDBTitle: crystal structure of geranyltransferase from helicobacter pylori 26695 Phyre2 PDB 2mom chain C Region: 47 - 77 Aligned: 23 Modelled: 31 Confidence: 28.3% Identity: 30% PDB header:membrane protein Chain: C: PDB Molecule:lysosome-associated membrane glycoprotein 2; PDBTitle: structural insights of tm domain of lamp-2a in dpc micelles Phyre2 PDB 2mom chain B Region: 47 - 77 Aligned: 23 Modelled: 31 Confidence: 25.7% Identity: 30% PDB header:membrane protein Chain: B: PDB Molecule:lysosome-associated membrane glycoprotein 2; PDBTitle: structural insights of tm domain of lamp-2a in dpc micelles Phyre2 PDB 5jfq chain B Region: 30 - 95 Aligned: 62 Modelled: 66 Confidence: 24.1% Identity: 18% PDB header:oxidoreductase Chain: B: PDB Molecule:geranylgeranyl pyrophosphate synthetase; PDBTitle: geranylgeranyl pyrophosphate synthetase from archaeon geoglobus2 acetivorans Phyre2 PDB 3p8r chain A Region: 30 - 96 Aligned: 63 Modelled: 67 Confidence: 19.1% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of polyprenyl synthase from vibrio cholerae Phyre2 PDB 2l4f chain A Region: 84 - 98 Aligned: 15 Modelled: 15 Confidence: 18.4% Identity: 40% PDB header:protein binding Chain: A: PDB Molecule:defective in cullin neddylation protein 1; PDBTitle: nmr structure of the uba domain of s. cerevisiae dcn1 bound to2 ubiquitin Phyre2 PDB 3m9u chain D Region: 26 - 96 Aligned: 71 Modelled: 71 Confidence: 16.5% Identity: 7% PDB header:transferase Chain: D: PDB Molecule:farnesyl-diphosphate synthase; PDBTitle: crystal structure of geranylgeranyl pyrophosphate synthase from2 lactobacillus brevis atcc 367 Phyre2 PDB 2hxg chain B Region: 43 - 112 Aligned: 69 Modelled: 70 Confidence: 15.9% Identity: 20% PDB header:isomerase Chain: B: PDB Molecule:l-arabinose isomerase; PDBTitle: crystal structure of mn2+ bound ecai Phyre2 PDB 3ts7 chain B Region: 30 - 96 Aligned: 67 Modelled: 67 Confidence: 14.8% Identity: 13% PDB header:transferase Chain: B: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of farnesyl diphosphate synthase (target efi-501951)2 from methylococcus capsulatus Phyre2 PDB 5xn5 chain A Region: 30 - 96 Aligned: 67 Modelled: 67 Confidence: 13.8% Identity: 6% PDB header:transferase Chain: A: PDB Molecule:os07g0580900 protein; PDBTitle: homo-dimer crystal structure of geranylgeranyl diphosphate synthases 12 from oryza sativa Phyre2 PDB 2fnq chain B Region: 66 - 112 Aligned: 42 Modelled: 47 Confidence: 12.7% Identity: 19% PDB header:oxidoreductase Chain: B: PDB Molecule:allene oxide synthase-lipoxygenase protein; PDBTitle: insights from the x-ray crystal structure of coral 8r-2 lipoxygenase: calcium activation via a c2-like domain and3 a structural basis of product chirality Phyre2 PDB 1kn0 chain A Region: 78 - 91 Aligned: 14 Modelled: 14 Confidence: 12.4% Identity: 29% Fold: dsRBD-like Superfamily: dsRNA-binding domain-like Family: The homologous-pairing domain of Rad52 recombinase Phyre2 PDB 3vf1 chain A Region: 66 - 112 Aligned: 42 Modelled: 47 Confidence: 10.8% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:11r-lipoxygenase; PDBTitle: structure of a calcium-dependent 11r-lipoxygenase suggests a mechanism2 for ca-regulation Phyre2 PDB 2p0m chain B Region: 66 - 118 Aligned: 48 Modelled: 53 Confidence: 10.7% Identity: 10% PDB header:oxidoreductase Chain: B: PDB Molecule:arachidonate 15-lipoxygenase; PDBTitle: revised structure of rabbit reticulocyte 15s-lipoxygenase Phyre2 PDB 5fno chain B Region: 66 - 112 Aligned: 42 Modelled: 47 Confidence: 10.4% Identity: 19% PDB header:oxidoreductase Chain: B: PDB Molecule:manganese lipoxygenase; PDBTitle: manganese lipoxygenase Phyre2 PDB 5h1q chain C Region: 64 - 95 Aligned: 31 Modelled: 32 Confidence: 9.7% Identity: 16% PDB header:transport protein Chain: C: PDB Molecule:innexin-6; PDBTitle: c. elegans inx-6 gap junction hemichannel Phyre2 PDB 1r4p chain B Region: 84 - 129 Aligned: 46 Modelled: 46 Confidence: 9.1% Identity: 22% Fold: OB-fold Superfamily: Bacterial enterotoxins Family: Bacterial AB5 toxins, B-subunits Phyre2 PDB 4f62 chain B Region: 30 - 91 Aligned: 58 Modelled: 62 Confidence: 9.1% Identity: 10% PDB header:transferase Chain: B: PDB Molecule:geranyltranstransferase; PDBTitle: crystal structure of a putative farnesyl-diphosphate synthase from2 marinomonas sp. med121 (target efi-501980) Phyre2 PDB 5fx8 chain A Region: 66 - 108 Aligned: 38 Modelled: 43 Confidence: 9.0% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:linoleate 11-lipoxygenase; PDBTitle: complete structure of manganese lipoxygenase of gaeumannomyces2 graminis and partial structure of zonadhesin of komagataella3 pastoris Phyre2 1 c4od5C_ 2 c3llwA_ 3 c2momC_ 4 c2momB_ 5 c5jfqB_ 6 c3p8rA_ 7 c2l4fA_ 8 c3m9uD_ 9 c2hxgB_ 10 c3ts7B_ 11 c5xn5A_ 12 c2fnqB_ 13 d1kn0a_ 14 c3vf1A_ 15 c2p0mB_ 16 c5fnoB_ 17 c5h1qC_ 18 d1r4pb_ 19 c4f62B_ 20 c5fx8A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36