1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	E	N	S	N	I	D	D	I	K	A	P	L	L	A	A	L	G	A	A	D	L	A	L	A	T	V	N	E	L	I	T	N	L	R	E	R	A	E	E	T	R	T	D	T	R	S	R	V	E	E	S	R	A	R	L	T	K	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																																				?	?	?															?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	E	D	L	P	E	Q	L	T	E	L	R	E	K	F	T	A	E	E	L	R	K	A	A	E	G	Y	L	E	A	A	T	S	R	Y	N	E	L	V	E	R	G	E	A	A	L	E	R	L	R	S	Q	Q	S	F	E	E	V	S	A
Secondary structure
SS confidence
Disorder		?	?	?		?	?																																											?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	A	E	G	Y	V	D	Q	A	V	E	L	T	Q	E	A	L	G	T	V	A	S	Q	T	R	A	V	G	E	R	A	A	K	L	V	G	I	E	L	P	K	K	A	A	P	A	K	K	A	A	P	A	K	K	A	A	P	A	K	K
Secondary structure
SS confidence
Disorder																																							?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.
Sequence		A	A	A	K	K	A	P	A	K	K	A	A	A	K	K	V	T	Q	K
Secondary structure
SS confidence
Disorder				?	?	?	?	?	?								?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 25%) Alpha helix ( 84%) Beta strand ( 0%)

Rank Aligned region

PDB 1nfo chain A Region: 25 - 87 Aligned: 63 Modelled: 63 Confidence: 70.5% Identity: 22% PDB header:lipid transport Chain: A: PDB Molecule:apolipoprotein e2; PDBTitle: apolipoprotein e2 (apoe2, d154a mutation) Phyre2 PDB 6f7s chain B Region: 71 - 102 Aligned: 32 Modelled: 32 Confidence: 61.7% Identity: 25% PDB header:rna binding protein Chain: B: PDB Molecule:serrate rna effector molecule homolog; PDBTitle: crystal structure of human ars2 residues 147-270 + 408-763 with2 deletion of loop b Phyre2 PDB 2jul chain A Region: 65 - 90 Aligned: 26 Modelled: 26 Confidence: 49.2% Identity: 38% PDB header:dna binding protein Chain: A: PDB Molecule:calsenilin; PDBTitle: nmr structure of dream Phyre2 PDB 6epg chain D Region: 38 - 77 Aligned: 40 Modelled: 40 Confidence: 29.1% Identity: 35% PDB header:toxin Chain: D: PDB Molecule:zeta_1 toxin; PDBTitle: structure of the epsilon_1 / zeta_1 antitoxin / toxin system from2 neisseria gonorrhoeae. Phyre2 PDB 1bjf chain A Region: 65 - 89 Aligned: 25 Modelled: 25 Confidence: 28.5% Identity: 36% Fold: EF Hand-like Superfamily: EF-hand Family: Calmodulin-like Phyre2 PDB 5x1h chain S Region: 60 - 119 Aligned: 58 Modelled: 60 Confidence: 28.3% Identity: 19% PDB header:protein transport Chain: S: PDB Molecule:icmj (dotn); PDBTitle: structure of legionella pneumophila dotn Phyre2 PDB 2yom chain A Region: 61 - 79 Aligned: 19 Modelled: 19 Confidence: 18.4% Identity: 37% PDB header:signaling protein Chain: A: PDB Molecule:sensory box protein; PDBTitle: solution nmr structure of the c-terminal extension of two bacterial2 light, oxygen, voltage (lov) photoreceptor proteins from3 pseudomonas putida Phyre2 PDB 1gw4 chain A Region: 39 - 74 Aligned: 36 Modelled: 36 Confidence: 17.9% Identity: 31% PDB header:high density lipoproteins Chain: A: PDB Molecule:apoa-i; PDBTitle: the helix-hinge-helix structural motif in human2 apolipoprotein a-i determined by nmr spectroscopy, 13 structure Phyre2 PDB 4jo6 chain Y Region: 60 - 75 Aligned: 16 Modelled: 16 Confidence: 16.8% Identity: 31% PDB header:unknown function Chain: Y: PDB Molecule:sbp-tag; PDBTitle: streptavidin complex with sbp-tag Phyre2 PDB 4jo6 chain Z Region: 60 - 75 Aligned: 16 Modelled: 16 Confidence: 16.8% Identity: 31% PDB header:unknown function Chain: Z: PDB Molecule:sbp-tag; PDBTitle: streptavidin complex with sbp-tag Phyre2 PDB 1dgn chain A Region: 68 - 109 Aligned: 42 Modelled: 42 Confidence: 16.4% Identity: 17% Fold: DEATH domain Superfamily: DEATH domain Family: Caspase recruitment domain, CARD Phyre2 PDB 5xzo chain A Region: 64 - 95 Aligned: 32 Modelled: 32 Confidence: 16.2% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:beta-xylanase; PDBTitle: crystal structure of gh10 xylanase xyl10c from bispora. sp mey-1 Phyre2 PDB 6cc4 chain A Region: 26 - 97 Aligned: 58 Modelled: 72 Confidence: 15.9% Identity: 28% PDB header:transport protein Chain: A: PDB Molecule:soluble cytochrome b562, lipid ii flippase murj chimera; PDBTitle: structure of murj from escherichia coli Phyre2 PDB 5kwo chain A Region: 74 - 87 Aligned: 14 Modelled: 14 Confidence: 15.3% Identity: 43% PDB header:de novo protein Chain: A: PDB Molecule:designed peptide nc_ehe_d1; PDBTitle: nmr solution structure of designed peptide nc_ehe_d1 Phyre2 PDB 6br8 chain B Region: 68 - 82 Aligned: 15 Modelled: 14 Confidence: 14.8% Identity: 27% PDB header:viral protein Chain: B: PDB Molecule:protein a6 homolog; PDBTitle: structure of a6 reveals a novel lipid transporter Phyre2 PDB 1ae9 chain A Region: 72 - 86 Aligned: 15 Modelled: 15 Confidence: 14.6% Identity: 33% Fold: DNA breaking-rejoining enzymes Superfamily: DNA breaking-rejoining enzymes Family: Lambda integrase-like, catalytic core Phyre2 PDB 1g8i chain A Region: 65 - 89 Aligned: 25 Modelled: 25 Confidence: 14.0% Identity: 36% Fold: EF Hand-like Superfamily: EF-hand Family: Calmodulin-like Phyre2 PDB 1ryl chain A Region: 67 - 103 Aligned: 37 Modelled: 37 Confidence: 13.3% Identity: 30% Fold: Hypothetical protein yfbM Superfamily: Hypothetical protein yfbM Family: Hypothetical protein yfbM Phyre2 PDB 6con chain F Region: 65 - 82 Aligned: 18 Modelled: 18 Confidence: 12.6% Identity: 22% PDB header:hydrolase Chain: F: PDB Molecule:coa-transferase subunit beta; PDBTitle: crystal structure of mycobacterium tuberculosis ipdab Phyre2 PDB 2jo8 chain B Region: 50 - 77 Aligned: 28 Modelled: 28 Confidence: 11.9% Identity: 29% PDB header:transferase Chain: B: PDB Molecule:serine/threonine-protein kinase 4; PDBTitle: solution structure of c-terminal domain of human mammalian2 sterile 20-like kinase 1 (mst1) Phyre2 1 c1nfoA_ 2 c6f7sB_ 3 c2julA_ 4 c6epgD_ 5 d1bjfa_ 6 c5x1hS_ 7 c2yomA_ 8 c1gw4A_ 9 c4jo6Y_ 10 c4jo6Z_ 11 d1dgna_ 12 c5xzoA_ 13 c6cc4A_ 14 c5kwoA_ 15 c6br8B_ 16 d1ae9a_ 17 d1g8ia_ 18 d1ryla_ 19 c6conF_ 20 c2jo8B_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99