1

.

.

.

.

.

.

.

.

10

.

.

.

.

.

.

.

.

.

20

.

.

.

.

.

.

.

.

.

30

.

.

.

.

.

.

.

.

.

40

.

.

.

.

.

.

.

.

.

50

.

.

.

.

.

.

.

.

.

60

Sequence

M

K

A

L

V

A

V

S

A

V

A

V

V

A

L

L

G

V

S

S

A

Q

A

D

P

E

A

D

P

G

A

G

E

A

N

Y

G

G

P

P

S

S

P

R

L

V

D

H

T

E

W

A

Q

W

G

S

L

P

S

L

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

.

.

.

.

.

.

.

.

70

.

.

.

.

.

.

.

.

.

80

.

.

.

.

.

.

.

.

.

90

.

.

.

.

.

.

.

.

.

100

.

.

.

.

.

.

.

.

.

110

.

.

.

.

.

.

.

.

.

120

Sequence

R

V

Y

P

S

Q

V

G

R

T

A

S

R

R

L

G

M

A

A

A

D

A

A

W

A

E

V

L

A

L

S

P

E

A

D

T

A

G

M

R

A

Q

F

I

C

H

W

Q

Y

A

E

I

R

Q

P

G

K

P

S

W

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

.

.

.

.

.

.

.

.

130

.

.

.

.

.

.

.

.

.

140

.

.

.

.

.

.

.

.

Sequence

N

L

E

P

W

R

P

V

V

D

D

S

E

M

L

A

S

G

C

N

P

G

S

P

E

E

S

F

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 42%) Alpha helix ( 43%) Beta strand ( 14%)

Rank Aligned region

PDB 2gts chain A domain 1 Region: 101 - 126 Aligned: 26 Modelled: 26 Confidence: 16.4% Identity: 31% Fold: Ferritin-like Superfamily: HP0062-like Family: HP0062-like Phyre2 PDB 2y69 chain X Region: 105 - 128 Aligned: 24 Modelled: 24 Confidence: 10.2% Identity: 21% PDB header:electron transport Chain: X: PDB Molecule:cytochrome c oxidase polypeptide 7b; PDBTitle: bovine heart cytochrome c oxidase re-refined with molecular oxygen Phyre2 PDB 1v54 chain K Region: 105 - 128 Aligned: 24 Modelled: 24 Confidence: 10.2% Identity: 21% Fold: Single transmembrane helix Superfamily: Mitochondrial cytochrome c oxidase subunit VIIb Family: Mitochondrial cytochrome c oxidase subunit VIIb Phyre2 PDB 2fgg chain A domain 1 Region: 137 - 147 Aligned: 11 Modelled: 11 Confidence: 8.4% Identity: 9% Fold: dsRBD-like Superfamily: Rv2632c-like Family: Rv2632c-like Phyre2 PDB 1tyk chain A Region: 135 - 143 Aligned: 9 Modelled: 9 Confidence: 7.4% Identity: 33% Fold: Knottins (small inhibitors, toxins, lectins) Superfamily: omega toxin-like Family: Spider toxins Phyre2 PDB 5we3 chain A Region: 135 - 141 Aligned: 7 Modelled: 7 Confidence: 7.3% Identity: 43% PDB header:toxin Chain: A: PDB Molecule:beta-theraphotoxin-ps1a; PDBTitle: solution nmr structure of paurtx-3 Phyre2 PDB 1niy chain A Region: 135 - 141 Aligned: 7 Modelled: 7 Confidence: 7.3% Identity: 57% Fold: Knottins (small inhibitors, toxins, lectins) Superfamily: omega toxin-like Family: Spider toxins Phyre2 PDB 1mb6 chain A Region: 135 - 141 Aligned: 7 Modelled: 7 Confidence: 7.2% Identity: 43% Fold: Knottins (small inhibitors, toxins, lectins) Superfamily: omega toxin-like Family: Spider toxins Phyre2 PDB 1m6k chain A Region: 116 - 141 Aligned: 26 Modelled: 26 Confidence: 6.9% Identity: 12% Fold: beta-lactamase/transpeptidase-like Superfamily: beta-lactamase/transpeptidase-like Family: beta-Lactamase/D-ala carboxypeptidase Phyre2 PDB 2cse chain B Region: 24 - 76 Aligned: 52 Modelled: 53 Confidence: 6.5% Identity: 33% PDB header:virus Chain: B: PDB Molecule:major outer-capsid protein mu1; PDBTitle: features of reovirus outer-capsid protein mu1 revealed by2 electron and image reconstruction of the virion at 7.0-a3 resolution Phyre2 PDB 3e6m chain D Region: 55 - 103 Aligned: 48 Modelled: 49 Confidence: 5.9% Identity: 8% PDB header:transcription regulator Chain: D: PDB Molecule:marr family transcriptional regulator; PDBTitle: the crystal structure of a marr family transcriptional2 regulator from silicibacter pomeroyi dss. Phyre2 PDB 4wpy chain A Region: 137 - 147 Aligned: 11 Modelled: 11 Confidence: 5.8% Identity: 18% PDB header:de novo protein Chain: A: PDB Molecule:protein dl-rv1738; PDBTitle: racemic crystal structure of rv1738 from mycobacterium tuberculosis2 (form-ii) Phyre2 PDB 1zjk chain A domain 2 Region: 122 - 142 Aligned: 21 Modelled: 21 Confidence: 5.4% Identity: 14% Fold: Complement control module/SCR domain Superfamily: Complement control module/SCR domain Family: Complement control module/SCR domain Phyre2 PDB 5v13 chain B Region: 119 - 132 Aligned: 14 Modelled: 14 Confidence: 5.4% Identity: 43% PDB header:hormone-binding protein Chain: B: PDB Molecule:aael008620-pa odorant-binding protein; PDBTitle: mosquito juvenile hormone-binding protein Phyre2 1 d2gtsa1 2 c2y69X_ 3 d1v54k_ 4 d2fgga1 5 d1tyka_ 6 c5we3A_ 7 d1niya_ 8 d1mb6a_ 9 d1m6ka_ 10 c2cseB_ 11 c3e6mD_ 12 c4wpyA_ 13 d1zjka2 14 c5v13B_