1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	T	S	S	L	P	T	V	Q	R	V	I	Q	N	A	L	E	V	S	Q	L	K	Y	S	Q	H	P	R	P	G	G	A	P	P	A	L	I	V	E	L	P	G	E	R	K	L	K	I	N	T	I	L	S	V	G	E	H	S	V	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?													?		?		?	?	?	?	?	?	?	?	?																							?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	E	A	F	V	C	R	K	P	D	E	N	R	E	D	V	Y	R	F	L	L	R	R	N	R	R	L	Y	G	V	A	Y	T	L	D	N	V	G	D	I	Y	L	V	G	Q	M	A	L	S	A	V	D	A	D	E	V	D	R	V	L
Secondary structure
SS confidence
Disorder																											?	?																			?		?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	Q	V	L	E	V	V	D	S	D	F	N	A	L	L	E	L	G	F	R	S	S	I	Q	R	E	W	Q	W	R	L	S	R	G	E	S	L	Q	N	L	Q	A	F	A	H	L	R	P	T	T	M	Q	S	A	Q	R	D	E	K	E
Secondary structure
SS confidence
Disorder																																	?					?										?	?	?	?	?	?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.
Sequence		L	G	G
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 25%) Alpha helix ( 46%) Beta strand ( 22%)

Rank Aligned region

PDB 2plg chain A domain 1 Region: 2 - 136 Aligned: 129 Modelled: 135 Confidence: 98.7% Identity: 16% Fold: Secretion chaperone-like Superfamily: Type III secretory system chaperone-like Family: Tll0839-like Phyre2 PDB 1jyo chain A Region: 5 - 129 Aligned: 116 Modelled: 125 Confidence: 97.1% Identity: 11% Fold: Secretion chaperone-like Superfamily: Type III secretory system chaperone-like Family: Type III secretory system chaperone Phyre2 PDB 4g6t chain A Region: 9 - 128 Aligned: 110 Modelled: 120 Confidence: 94.0% Identity: 12% PDB header:chaperone Chain: A: PDB Molecule:type iii chaperone protein shca; PDBTitle: structure of the hopa1-scha chaperone-effector complex Phyre2 PDB 3epu chain B Region: 8 - 138 Aligned: 122 Modelled: 131 Confidence: 93.8% Identity: 13% PDB header:chaperone Chain: B: PDB Molecule:stm2138 virulence chaperone; PDBTitle: crystal structure of stm2138, a novel virulence chaperone in2 salmonella Phyre2 PDB 1k3e chain A Region: 7 - 129 Aligned: 114 Modelled: 119 Confidence: 93.7% Identity: 10% Fold: Secretion chaperone-like Superfamily: Type III secretory system chaperone-like Family: Type III secretory system chaperone Phyre2 PDB 1ttw chain A Region: 7 - 129 Aligned: 113 Modelled: 123 Confidence: 91.9% Identity: 13% Fold: Secretion chaperone-like Superfamily: Type III secretory system chaperone-like Family: Type III secretory system chaperone Phyre2 PDB 6j7a chain B Region: 69 - 99 Aligned: 31 Modelled: 31 Confidence: 67.2% Identity: 29% PDB header:oxidoreductase Chain: B: PDB Molecule:heme oxygenase 1,nadph--cytochrome p450 reductase; PDBTitle: fusion protein of heme oxygenase-1 and nadph cytochrome p450 reductase2 (17aa) Phyre2 PDB 1xkp chain C domain 1 Region: 67 - 123 Aligned: 57 Modelled: 57 Confidence: 56.8% Identity: 21% Fold: Secretion chaperone-like Superfamily: Type III secretory system chaperone-like Family: Type III secretory system chaperone Phyre2 PDB 1ul7 chain A Region: 2 - 92 Aligned: 62 Modelled: 68 Confidence: 56.3% Identity: 29% Fold: TBP-like Superfamily: KA1-like Family: Kinase associated domain 1, KA1 Phyre2 PDB 4akx chain A Region: 75 - 125 Aligned: 51 Modelled: 51 Confidence: 55.8% Identity: 25% PDB header:transport protein Chain: A: PDB Molecule:spcu; PDBTitle: structure of the heterodimeric complex exou-spcu from the type iii2 secretion system (t3ss) of pseudomonas aeruginosa Phyre2 PDB 3tu3 chain A Region: 75 - 125 Aligned: 51 Modelled: 51 Confidence: 55.3% Identity: 25% PDB header:toxin/toxin chaperone Chain: A: PDB Molecule:exou chaperone; PDBTitle: 1.92 angstrom resolution crystal structure of the full-length spcu in2 complex with full-length exou from the type iii secretion system of3 pseudomonas aeruginosa Phyre2 PDB 1j9z chain B Region: 69 - 99 Aligned: 31 Modelled: 31 Confidence: 52.6% Identity: 29% PDB header:oxidoreductase Chain: B: PDB Molecule:nadph-cytochrome p450 reductase; PDBTitle: cypor-w677g Phyre2 PDB 6efv chain A Region: 68 - 99 Aligned: 32 Modelled: 32 Confidence: 45.3% Identity: 25% PDB header:flavoprotein Chain: A: PDB Molecule:sulfite reductase [nadph] flavoprotein alpha-component; PDBTitle: the nadph-dependent sulfite reductase flavoprotein adopts an extended2 conformation that is unique to this diflavin reductase Phyre2 PDB 1ja1 chain A domain 2 Region: 69 - 99 Aligned: 31 Modelled: 31 Confidence: 44.2% Identity: 29% Fold: Flavodoxin-like Superfamily: Flavoproteins Family: Cytochrome p450 reductase N-terminal domain-like Phyre2 PDB 2akj chain A domain 1 Region: 83 - 129 Aligned: 46 Modelled: 47 Confidence: 43.5% Identity: 15% Fold: Ferredoxin-like Superfamily: Nitrite/Sulfite reductase N-terminal domain-like Family: Duplicated SiR/NiR-like domains 1 and 3 Phyre2 PDB 2j58 chain G Region: 92 - 125 Aligned: 34 Modelled: 34 Confidence: 39.7% Identity: 18% PDB header:membrane protein Chain: G: PDB Molecule:outer membrane lipoprotein wza; PDBTitle: the structure of wza Phyre2 PDB 2b3a chain A domain 1 Region: 10 - 48 Aligned: 34 Modelled: 39 Confidence: 37.2% Identity: 32% Fold: beta-Grasp (ubiquitin-like) Superfamily: Ubiquitin-like Family: Ras-binding domain, RBD Phyre2 PDB 1b1c chain A Region: 69 - 99 Aligned: 31 Modelled: 31 Confidence: 36.4% Identity: 29% Fold: Flavodoxin-like Superfamily: Flavoproteins Family: Cytochrome p450 reductase N-terminal domain-like Phyre2 PDB 3hr4 chain C Region: 68 - 99 Aligned: 32 Modelled: 32 Confidence: 35.1% Identity: 16% PDB header:oxidoreductase/metal binding protein Chain: C: PDB Molecule:nitric oxide synthase, inducible; PDBTitle: human inos reductase and calmodulin complex Phyre2 PDB 3qrz chain C Region: 40 - 75 Aligned: 34 Modelled: 36 Confidence: 34.7% Identity: 26% PDB header:hormone receptor Chain: C: PDB Molecule:abscisic acid receptor pyl5; PDBTitle: crystal structure of native abscisic acid receptor pyl5 at 2.62 angstrom Phyre2 1 d2plga1 2 d1jyoa_ 3 c4g6tA_ 4 c3epuB_ 5 d1k3ea_ 6 d1ttwa_ 7 c6j7aB_ 8 d1xkpc1 9 d1ul7a_ 10 c4akxA_ 11 c3tu3A_ 12 c1j9zB_ 13 c6efvA_ 14 d1ja1a2 15 d2akja1 16 c2j58G_ 17 d2b3aa1 18 d1b1ca_ 19 c3hr4C_ 20 c3qrzC_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99