Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD0507_(mmpL2)_597202_600108
DateFri Jul 26 01:50:05 BST 2019
Unique Job ID61fd7b28a5cbeed5
SequenceMSERHAALTS ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:64.682 Y:90.450 Z:92.019
Model (left) based on template c6ajjA_
Top template information
PDB header:membrane protein, hydrolase
Chain: A: PDB Molecule:drug exporters of the rnd superfamily-like protein,
PDBTitle: crystal structure of mycolic acid transporter mmpl3 from mycobacterium2 smegmatis complexed with ica38
Confidence and coverage
Confidence:100.0% Coverage: 72%
697 residues ( 72% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
931 residues ( 96%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in JSmol
For other options to view your downloaded structure offline see the FAQ

Sequence analysis 

Download FASTA version

Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c6ajjA_
100.0 19
PDB header:membrane protein, hydrolase
Chain: A: PDB Molecule:drug exporters of the rnd superfamily-like protein,
PDBTitle: crystal structure of mycolic acid transporter mmpl3 from mycobacterium2 smegmatis complexed with ica38
2c5lq3F_
100.0 12
PDB header:transport protein
Chain: F: PDB Molecule:cmeb;
PDBTitle: structures and transport dynamics of the campylobacter jejuni2 multidrug efflux pump cmeb
3c3k07A_
100.0 15
PDB header:transport protein
Chain: A: PDB Molecule:cation efflux system protein cusa;
PDBTitle: crystal structure of cusa
4c4mt1A_
100.0 13
PDB header:membrane protein, tranport protein
Chain: A: PDB Molecule:drug efflux protein;
PDBTitle: crystal structure of the neisseria gonorrhoeae mtrd inner membrane2 multidrug efflux pump
5c6owsB_
100.0 11
PDB header:membrane protein
Chain: B: PDB Molecule:efflux pump membrane transporter;
PDBTitle: cryo-em structure of an acinetobacter baumannii multidrug efflux pump
6c2v50A_
100.0 12
PDB header:membrane protein
Chain: A: PDB Molecule:multidrug resistance protein mexb;
PDBTitle: the missing part of the bacterial mexab-oprm system: structural2 determination of the multidrug exporter mexb
7c4k0eA_
100.0 15
PDB header:transport protein
Chain: A: PDB Molecule:heavy metal cation tricomponent efflux pump znea(czca-
PDBTitle: x-ray crystal structure of a heavy metal efflux pump, crystal form ii
8c6dmoA_
100.0 15
PDB header:protein binding
Chain: A: PDB Molecule:protein patched homolog 1;
PDBTitle: cryo-em structure of human ptch1 with three mutations2 l282q/t500f/p504l
9c1oy8A_
100.0 12
PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
10c5khnB_
100.0 17
PDB header:membrane protein
Chain: B: PDB Molecule:rnd transporter;
PDBTitle: crystal structures of the burkholderia multivorans hopanoid2 transporter hpnn
11c6csxA_
100.0 11
PDB header:transport protein
Chain: A: PDB Molecule:multidrug efflux pump subunit acrb;
PDBTitle: single particles cryo-em structure of acrb d407a associated with lipid2 bilayer at 3.0 angstrom
12c4k0eC_
100.0 15
PDB header:transport protein
Chain: C: PDB Molecule:heavy metal cation tricomponent efflux pump znea(czca-
PDBTitle: x-ray crystal structure of a heavy metal efflux pump, crystal form ii
13c3jd8A_
100.0 15
PDB header:membrane protein
Chain: A: PDB Molecule:niemann-pick c1 protein;
PDBTitle: cryo-em structure of the full-length human npc1 at 4.4 angstrom
14c3aqpB_
100.0 15
PDB header:membrane protein
Chain: B: PDB Molecule:probable secdf protein-export membrane protein;
PDBTitle: crystal structure of secdf, a translocon-associated membrane protein,2 from thermus thrmophilus
15c5xamA_
100.0 13
PDB header:membrane protein
Chain: A: PDB Molecule:protein translocase subunit secd;
PDBTitle: crystal structure of secdf in i form at 4 a resolution
16c5mg3D_
100.0 14
PDB header:chaperone
Chain: D: PDB Molecule:protein translocase subunit secd;
PDBTitle: em fitted model of bacterial holo-translocon
17c5mg3F_
99.9 11
PDB header:chaperone
Chain: F: PDB Molecule:protein translocase subunit secf;
PDBTitle: em fitted model of bacterial holo-translocon
18d1iwga8
99.9 14
Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
19d1iwga7
99.9 15
Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
20c5ensA_
99.5 9
PDB header:transport protein
Chain: A: PDB Molecule:multidrug efflux pump subunit acrb,multidrug efflux pump
PDBTitle: rhodamine bound structure of bacterial efflux pump.
21c4r86B_
not modelled 98.8 5
PDB header:protein transport
Chain: B: PDB Molecule:rnd family aminoglycoside/multidrug efflux pump;
PDBTitle: crystal structure of aminoglycoside/multidrug efflux system acrd from2 salmonella typhimurium
22d1iwga3
not modelled 95.2 10
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
23d1iwga6
not modelled 88.2 9
Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
24c2yvxD_
not modelled 86.1 10
PDB header:transport protein
Chain: D: PDB Molecule:mg2+ transporter mgte;
PDBTitle: crystal structure of magnesium transporter mgte
25d1iwga4
not modelled 82.5 14
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
26c4av3A_
not modelled 74.6 10
PDB header:hydrolase
Chain: A: PDB Molecule:k(+)-stimulated pyrophosphate-energized sodium pump;
PDBTitle: crystal structure of thermotoga maritima sodium pumping membrane2 integral pyrophosphatase with metal ions in active site
27c5f1bC_
not modelled 66.6 22
PDB header:viral protein/transport protein
Chain: C: PDB Molecule:niemann-pick c1 protein;
PDBTitle: structural basis of ebola virus entry: viral glycoprotein bound to its2 endosomal receptor niemann-pick c1
28d1iwga2
not modelled 66.0 9
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
29c5zlgA_
not modelled 39.7 13
PDB header:oxidoreductase
Chain: A: PDB Molecule:cytochrome b reductase 1;
PDBTitle: human duodenal cytochrome b (dcytb) in zinc ion and ascorbate bound2 form
30d2yvxa3
not modelled 27.7 9
Fold:MgtE membrane domain-like
Superfamily:MgtE membrane domain-like
Family:MgtE membrane domain-like
31d1iwga5
not modelled 27.6 1
Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
32c2mkaC_
not modelled 23.5 17
PDB header:immune system
Chain: C: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
33c2mkaA_
not modelled 23.5 17
PDB header:immune system
Chain: A: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
34c2mk9A_
not modelled 23.5 17
PDB header:immune system
Chain: A: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the dimeric transmembrane domain of toll-like2 receptor 3
35c2mkaB_
not modelled 23.5 17
PDB header:immune system
Chain: B: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
36c2mk9B_
not modelled 23.5 17
PDB header:immune system
Chain: B: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the dimeric transmembrane domain of toll-like2 receptor 3
37c1ciiA_
not modelled 20.1 11
PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia
38c2bbjB_
not modelled 16.7 12
PDB header:metal transport/membrane protein
Chain: B: PDB Molecule:divalent cation transport-related protein;
PDBTitle: crystal structure of the cora mg2+ transporter
39d1iwga1
not modelled 16.5 8
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
40c6n52B_
not modelled 15.0 14
PDB header:membrane protein
Chain: B: PDB Molecule:metabotropic glutamate receptor 5;
PDBTitle: metabotropic glutamate receptor 5 apo form
41c1a87A_
not modelled 14.9 12
PDB header:bacteriocin
Chain: A: PDB Molecule:colicin n;
PDBTitle: colicin n
42d1a87a_
not modelled 14.9 12
Fold:Toxins' membrane translocation domains
Superfamily:Colicin
Family:Colicin
43c2jo1A_
not modelled 14.4 18
PDB header:hydrolase regulator
Chain: A: PDB Molecule:phospholemman;
PDBTitle: structure of the na,k-atpase regulatory protein fxyd1 in2 micelles
44c2kseA_
not modelled 13.1 33
PDB header:transferase
Chain: A: PDB Molecule:sensor protein qsec;
PDBTitle: backbone structure of the membrane domain of e. coli histidine kinase2 receptor qsec, center for structures of membrane proteins (csmp)3 target 4311c
45c5n9yB_
not modelled 12.3 13
PDB header:membrane protein
Chain: B: PDB Molecule:zinc transport protein zntb;
PDBTitle: the full-length structure of zntb
46c1p58F_
not modelled 12.3 17
PDB header:virus
Chain: F: PDB Molecule:envelope protein m;
PDBTitle: complex organization of dengue virus membrane proteins as revealed by2 9.5 angstrom cryo-em reconstruction
47c1vw4b_
not modelled 12.1 29
PDB header:ribosome
Chain: B: PDB Molecule:
PDBTitle: structure of the yeast mitochondrial large ribosomal subunit
48c6fkip_
not modelled 11.8 6
PDB header:membrane protein
Chain: P: PDB Molecule:atp synthase subunit c, chloroplastic;
PDBTitle: chloroplast f1fo conformation 3
49d1jb0i_
not modelled 11.7 19
Fold:Single transmembrane helix
Superfamily:Subunit VIII of photosystem I reaction centre, PsaI
Family:Subunit VIII of photosystem I reaction centre, PsaI
50c4fe1I_
not modelled 11.7 19
PDB header:photosynthesis
Chain: I: PDB Molecule:photosystem i reaction center subunit viii;
PDBTitle: improving the accuracy of macromolecular structure refinement at 7 a2 resolution
51c5ws4A_
not modelled 11.7 14
PDB header:membrane protein
Chain: A: PDB Molecule:macrolide export atp-binding/permease protein macb;
PDBTitle: crystal structure of tripartite-type abc transporter macb from2 acinetobacter baumannii
52c3eamB_
not modelled 11.3 10
PDB header:membrane protein, transport protein
Chain: B: PDB Molecule:glr4197 protein;
PDBTitle: an open-pore structure of a bacterial pentameric ligand-2 gated ion channel
53c2m1hA_
not modelled 11.2 60
PDB header:transcription
Chain: A: PDB Molecule:transcription elongation factor s-ii;
PDBTitle: solution structure of a pwwp domain from trypanosoma brucei
54c1gk7A_
not modelled 11.0 17
PDB header:vimentin
Chain: A: PDB Molecule:vimentin;
PDBTitle: human vimentin coil 1a fragment (1a)
55d1gmnb1
not modelled 10.8 36
Fold:Hairpin loop containing domain-like
Superfamily:Hairpin loop containing domain-like
Family:Hairpin loop containing domain
56c6dkuA_
not modelled 10.5 7
PDB header:unknown function
Chain: A: PDB Molecule:vp35;
PDBTitle: crystal structure of myotis vp35 mutant of interferon inhibitory2 domain
57c2n1pA_
not modelled 10.3 17
PDB header:viral protein
Chain: A: PDB Molecule:non-structural protein 5b, ns5b;
PDBTitle: structure of the c-terminal membrane domain of hcv ns5b protein
58c2lonA_
not modelled 10.3 15
PDB header:membrane protein
Chain: A: PDB Molecule:hig1 domain family member 1b;
PDBTitle: backbone structure of human membrane protein higd1b
59d1qmga1
not modelled 10.3 13
Fold:6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like
Family:Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)
60c5ho5D_
not modelled 10.1 18
PDB header:metal transport
Chain: D: PDB Molecule:magnetosome protein mamb;
PDBTitle: mamb
61c2lgxA_
not modelled 10.0 22
PDB header:cell adhesion
Chain: A: PDB Molecule:fermitin family homolog 2;
PDBTitle: nmr structure for kindle-2 n-terminus
62c5wvmA_
not modelled 9.8 18
PDB header:sugar binding protein
Chain: A: PDB Molecule:maltose-binding periplasmic protein,two-component system
PDBTitle: crystal structure of baes cocrystallized with 2 mm indole
63c6fkib_
not modelled 9.5 11
PDB header:membrane protein
Chain: B: PDB Molecule:atp synthase subunit beta, chloroplastic;
PDBTitle: chloroplast f1fo conformation 3
64c2kncB_
not modelled 9.5 13
PDB header:cell adhesion
Chain: B: PDB Molecule:integrin beta-3;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex
65c2k1lA_
not modelled 9.4 16
PDB header:signaling protein
Chain: A: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 6.3
66c2k1lB_
not modelled 9.4 16
PDB header:signaling protein
Chain: B: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 6.3
67c2k1kA_
not modelled 9.4 16
PDB header:signaling protein
Chain: A: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 4.3
68c2k1kB_
not modelled 9.4 16
PDB header:signaling protein
Chain: B: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 4.3
69d2hkua2
not modelled 9.4 20
Fold:Tetracyclin repressor-like, C-terminal domain
Superfamily:Tetracyclin repressor-like, C-terminal domain
Family:Tetracyclin repressor-like, C-terminal domain
70c6b2zf_
not modelled 9.3 14
PDB header:membrane protein
Chain: F: PDB Molecule:atp synthase subunit c, mitochondrial;
PDBTitle: cryo-em structure of the dimeric fo region of yeast mitochondrial atp2 synthase
71c2mkvA_
not modelled 9.3 22
PDB header:transport protein
Chain: A: PDB Molecule:sodium/potassium-transporting atpase subunit gamma;
PDBTitle: structure of the na,k-atpase regulatory protein fxyd2b in micelles
72c2f1fA_
not modelled 9.1 12
PDB header:transferase
Chain: A: PDB Molecule:acetolactate synthase isozyme iii small subunit;
PDBTitle: crystal structure of the regulatory subunit of acetohydroxyacid2 synthase isozyme iii from e. coli
73c3zm8A_
not modelled 9.1 56
PDB header:hydrolase
Chain: A: PDB Molecule:gh26 endo-beta-1,4-mannanase;
PDBTitle: crystal structure of podospora anserina gh26-cbm352 beta-(1,4)-mannanase
74c2ww9B_
not modelled 9.1 3
PDB header:ribosome
Chain: B: PDB Molecule:protein transport protein sss1;
PDBTitle: cryo-em structure of the active yeast ssh1 complex bound to the yeast2 80s ribosome
75d1khca_
not modelled 9.1 27
Fold:SH3-like barrel
Superfamily:Tudor/PWWP/MBT
Family:PWWP domain
76c2lowA_
not modelled 8.9 33
PDB header:membrane protein
Chain: A: PDB Molecule:apelin receptor;
PDBTitle: solution structure of ar55 in 50% hfip
77c2bvtB_
not modelled 8.7 50
PDB header:hydrolase
Chain: B: PDB Molecule:beta-1,4-mannanase;
PDBTitle: the structure of a modular endo-beta-1,4-mannanase from cellulomonas2 fimi explains the product specificity of glycoside hydrolase family3 26 mannanases.
78c3ofgA_
not modelled 8.7 11
PDB header:chaperone
Chain: A: PDB Molecule:boca/mesd chaperone for ywtd beta-propeller-egf protein 1;
PDBTitle: structured domain of caenorhabditis elegans bmy-1
79c6c08F_
not modelled 8.7 20
PDB header:membrane protein
Chain: F: PDB Molecule:sodium-coupled neutral amino acid transporter 9;
PDBTitle: zebrafish slc38a9 with arginine bound in the cytosol open state
80c6b8ht_
not modelled 8.7 14
PDB header:membrane protein
Chain: T: PDB Molecule:atp synthase subunit 9, mitochondrial;
PDBTitle: mosaic model of yeast mitochondrial atp synthase monomer
81c5oonA_
not modelled 8.7 14
PDB header:membrane protein
Chain: A: PDB Molecule:undecaprenyl-diphosphatase;
PDBTitle: structure of undecaprenyl-pyrophosphate phosphatase, baca
82c3l2uA_
not modelled 8.5 21
PDB header:recombination/dna
Chain: A: PDB Molecule:integrase;
PDBTitle: crystal structure of the prototype foamy virus (pfv)2 intasome in complex with magnesium and gs91373 (elvitegravir)
83c3v7oA_
not modelled 8.4 17
PDB header:transcription
Chain: A: PDB Molecule:minor nucleoprotein vp30;
PDBTitle: crystal structure of the c-terminal domain of ebola virus vp30 (strain2 reston-89)
84c4gn0D_
not modelled 8.3 9
PDB header:signaling protein
Chain: D: PDB Molecule:hamp domain of af1503;
PDBTitle: de novo phasing of a hamp-complex using an improved arcimboldo method
85c6mctC_
not modelled 8.1 14
PDB header:de novo protein
Chain: C: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
86c6mctJ_
not modelled 8.1 14
PDB header:de novo protein
Chain: J: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
87c6mctN_
not modelled 8.1 14
PDB header:de novo protein
Chain: N: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
88c6mctM_
not modelled 8.1 14
PDB header:de novo protein
Chain: M: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
89c6mctI_
not modelled 8.1 14
PDB header:de novo protein
Chain: I: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
90c6mctO_
not modelled 8.1 14
PDB header:de novo protein
Chain: O: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
91c6mctK_
not modelled 8.1 14
PDB header:de novo protein
Chain: K: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
92c6mctE_
not modelled 8.1 14
PDB header:de novo protein
Chain: E: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
93c6mctH_
not modelled 8.1 14
PDB header:de novo protein
Chain: H: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
94c6mctB_
not modelled 8.1 14
PDB header:de novo protein
Chain: B: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
95c6mctL_
not modelled 8.1 14
PDB header:de novo protein
Chain: L: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
96c6mctG_
not modelled 8.1 14
PDB header:de novo protein
Chain: G: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
97c6mctD_
not modelled 8.1 14
PDB header:de novo protein
Chain: D: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
98c6mpwA_
not modelled 8.1 14
PDB header:de novo protein
Chain: A: PDB Molecule:mini-evgl membrane protein;
PDBTitle: de novo design of membrane protein--mini-evgl membrane protein, c22212 form-1
99c6mq2D_
not modelled 8.1 14
PDB header:de novo protein
Chain: D: PDB Molecule:mini-evgl membrane protein;
PDBTitle: de novo design of membrane protein--mini-evgl membrane protein, c22212 form-2

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below