1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	R	I	G	R	R	E	G	L	A	V	A	I	G	F	V	L	V	G	A	A	F	V	L	P	R	L	N	L	G	I	K	P	R	S	D	I	G	L	E	R	F	A	T	R	A	G	A	A	P	I	F	G	Y	W	D	A	H	V	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																					?	?					?	?	?	?		?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		W	G	T	A	P	A	V	L	T	A	V	A	V	V	A	W	G	P	V	V	A	H	R	L	P	W	R	V	L	T	L	S	T	W	A	T	A	A	A	W	A	F	S	L	A	M	I	D	G	W	Q	R	G	F	A	G	R	L	T	T
Secondary structure
SS confidence
Disorder																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	D	E	Y	L	W	Q	V	P	G	I	A	D	I	P	A	T	L	R	T	F	T	S	R	I	L	D	F	Q	P	N	S	W	V	T	H	V	S	G	H	P	P	G	A	L	L	T	F	V	W	L	D	R	I	G	L	R	G	G	G
Secondary structure
SS confidence
Disorder																															?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		W	A	G	L	V	C	L	L	V	G	S	S	A	A	A	A	V	L	I	A	V	R	V	L	A	S	E	Q	M	A	R	R	T	A	P	F	V	A	V	A	P	T	A	I	W	I	A	V	S	A	D	G	Y	F	A	G	V	A	A	W
Secondary structure
SS confidence
Disorder																									?	?	?																	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	I	A	L	L	A	V	A	V	H	G	A	T	R	F	P	A	L	V	A	A	G	A	G	L	L	L	G	W	G	V	F	L	N	Y	G	L	V	L	I	V	L	P	G	M	A	V	L	A	A	A	D	W	R	P	V	L	R	A	L
Secondary structure
SS confidence
Disorder																																																								?		?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	P	A	V	L	A	A	L	V	V	A	V	S	F	A	V	A	G	F	S	W	F	D	G	Y	T	L	V	Q	Q	R	Y	W	Q	G	I	A	K	D	R	P	F	G	Y	W	S	W	A	N	L	A	C	V	V	C	A	I	G	L	G
Secondary structure
SS confidence
Disorder																																			?		?																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		S	V	A	G	L	S	R	V	F	D	R	A	A	I	S	R	R	S	G	C	H	L	L	L	L	A	V	L	A	A	I	A	L	A	D	L	S	M	L	S	K	A	E	T	E	R	I	W	L	P	F	T	I	W	L	T	A	A	P	A
Secondary structure
SS confidence
Disorder											?	?	?	?	?	?	?	?		?	?	?															?	?	?	?	?																			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.
Sequence		L	L	P	P	R	S	H	R	L	W	L	A	V	N	A	A	G	A	L	L	L	N	S	I	I	F	T	N	W
Secondary structure
SS confidence
Disorder		?	?	?																						?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 13%) Alpha helix ( 73%) Beta strand ( 0%) TM helix ( 52%) (View membrane topology prediction)

Rank Aligned region

PDB 5f15 chain A Region: 160 - 447 Aligned: 280 Modelled: 288 Confidence: 98.6% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:4-amino-4-deoxy-l-arabinose (l-ara4n) transferase; PDBTitle: crystal structure of arnt from cupriavidus metallidurans bound to2 undecaprenyl phosphate Phyre2 PDB 3rce chain A Region: 68 - 310 Aligned: 215 Modelled: 215 Confidence: 96.7% Identity: 12% PDB header:transferase/peptide Chain: A: PDB Molecule:oligosaccharide transferase to n-glycosylate proteins; PDBTitle: bacterial oligosaccharyltransferase pglb Phyre2 PDB 6p2r chain B Region: 125 - 319 Aligned: 190 Modelled: 195 Confidence: 95.5% Identity: 13% PDB header:transferase Chain: B: PDB Molecule:dolichyl-phosphate-mannose--protein mannosyltransferase 2; PDBTitle: structure of s. cerevisiae protein o-mannosyltransferase pmt1-pmt22 complex bound to the sugar donor Phyre2 PDB 3waj chain A Region: 137 - 401 Aligned: 256 Modelled: 265 Confidence: 92.5% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:transmembrane oligosaccharyl transferase; PDBTitle: crystal structure of the archaeoglobus fulgidus2 oligosaccharyltransferase (o29867_arcfu) complex with zn and sulfate Phyre2 PDB 6p25 chain A Region: 125 - 319 Aligned: 190 Modelled: 195 Confidence: 91.8% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:dolichyl-phosphate-mannose--protein mannosyltransferase 1; PDBTitle: structure of s. cerevisiae protein o-mannosyltransferase pmt1-pmt22 complex bound to the sugar donor and a peptide acceptor Phyre2 PDB 6ezn chain F Region: 87 - 326 Aligned: 235 Modelled: 240 Confidence: 88.1% Identity: 11% PDB header:membrane protein Chain: F: PDB Molecule:dolichyl-diphosphooligosaccharide--protein PDBTitle: cryo-em structure of the yeast oligosaccharyltransferase (ost) complex Phyre2 PDB 6adq chain P Region: 387 - 412 Aligned: 26 Modelled: 26 Confidence: 21.4% Identity: 19% PDB header:electron transport Chain: P: PDB Molecule:prokaryotic respiratory supercomplex associate factor 1 PDBTitle: respiratory complex ciii2civ2sod2 from mycobacterium smegmatis Phyre2 PDB 5zcr chain B Region: 107 - 159 Aligned: 50 Modelled: 53 Confidence: 9.4% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:maltooligosyl trehalose synthase; PDBTitle: dsm5389 glycosyltrehalose synthase Phyre2 PDB 5gxw chain B Region: 56 - 64 Aligned: 9 Modelled: 9 Confidence: 7.8% Identity: 44% PDB header:protein binding Chain: B: PDB Molecule:peptide from nuclear mitotic apparatus protein 1; PDBTitle: importin and numa complex Phyre2 PDB 2wa0 chain A Region: 116 - 156 Aligned: 41 Modelled: 41 Confidence: 6.7% Identity: 15% PDB header:immune system Chain: A: PDB Molecule:melanoma-associated antigen 4; PDBTitle: crystal structure of the human magea4 Phyre2 PDB 3nw0 chain B Region: 116 - 156 Aligned: 41 Modelled: 41 Confidence: 6.5% Identity: 17% PDB header:metal binding protein Chain: B: PDB Molecule:melanoma-associated antigen g1; PDBTitle: crystal structure of mageg1 and nse1 complex Phyre2 PDB 2lx0 chain A Region: 304 - 322 Aligned: 19 Modelled: 19 Confidence: 5.9% Identity: 42% PDB header:membrane protein Chain: A: PDB Molecule:membrane fusion protein p14; PDBTitle: arced helix (arch) nmr structure of the reovirus p14 fusion-associated2 small transmembrane (fast) protein transmembrane domain (tmd) in3 dodecyl phosphocholine (dpc) micelles Phyre2 PDB 6cfw chain G Region: 5 - 83 Aligned: 77 Modelled: 79 Confidence: 5.3% Identity: 12% PDB header:membrane protein Chain: G: PDB Molecule:monovalent cation/h+ antiporter subunit c; PDBTitle: cryoem structure of a respiratory membrane-bound hydrogenase Phyre2 1 c5f15A_ 2 c3rceA_ 3 c6p2rB_ 4 c3wajA_ 5 c6p25A_ 6 c6eznF_ 7 c6adqP_ 8 c5zcrB_ 9 c5gxwB_ 10 c2wa0A_ 11 c3nw0B_ 12 c2lx0A_ 13 c6cfwG_