1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	I	L	A	S	R	M	L	L	R	P	A	D	Y	Q	R	S	L	S	F	Y	R	D	Q	I	G	L	A	I	A	R	E	Y	G	A	G	T	V	F	F	A	G	Q	S	L	L	E	L	A	G	Y	G	E	P	D	H	S	R	G
Secondary structure
SS confidence
Disorder		?	?	?																																																			?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	F	P	G	A	L	W	L	Q	V	R	D	L	E	A	T	Q	T	E	L	V	S	R	G	V	S	I	A	R	E	P	R	R	E	P	W	G	L	H	E	M	H	V	T	D	P	D	G	I	T	L	I	F	V	E	V	P	E	G	H
Secondary structure
SS confidence
Disorder																																																											?
Disorder confidence
		.	.	.	.	.	.	.	.
Sequence		P	L	R	T	D	T	R	A
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 14%) Alpha helix ( 16%) Beta strand ( 42%)

Rank Aligned region

PDB 2i7r chain A domain 1 Region: 5 - 117 Aligned: 113 Modelled: 113 Confidence: 99.9% Identity: 14% Fold: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family: Antibiotic resistance proteins Phyre2 PDB 3bt3 chain B Region: 3 - 116 Aligned: 114 Modelled: 114 Confidence: 99.9% Identity: 14% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:glyoxalase-related enzyme, arac type; PDBTitle: crystal structure of a glyoxalase-related enzyme from clostridium2 phytofermentans Phyre2 PDB 4nvs chain B Region: 4 - 115 Aligned: 112 Modelled: 112 Confidence: 99.9% Identity: 19% PDB header:unknown function Chain: B: PDB Molecule:putative enzyme, glyoxalase family; PDBTitle: crystal structure of the q18cp6_clod6 protein from glyoxalase family.2 northeast structural genomics consortium target cfr3 Phyre2 PDB 2r6u chain B Region: 1 - 118 Aligned: 118 Modelled: 118 Confidence: 99.8% Identity: 19% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of gene product rha04853 from rhodococcus sp. rha1 Phyre2 PDB 4hc5 chain A Region: 1 - 115 Aligned: 115 Modelled: 113 Confidence: 99.8% Identity: 22% PDB header:oxidoreductase Chain: A: PDB Molecule:glyoxalase/bleomycin resistance protein/dioxygenase; PDBTitle: crystal structure of member of glyoxalase/bleomycin resistance2 protein/dioxygenase superfamily from sphaerobacter thermophilus dsm3 20745 Phyre2 PDB 3bqx chain A Region: 4 - 127 Aligned: 123 Modelled: 124 Confidence: 99.8% Identity: 20% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:glyoxalase-related enzyme; PDBTitle: high resolution crystal structure of a glyoxalase-related enzyme from2 fulvimarina pelagi Phyre2 PDB 3r6a chain B Region: 1 - 118 Aligned: 117 Modelled: 117 Confidence: 99.8% Identity: 24% PDB header:isomerase, lyase Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an uncharacterized protein (hypothetical protein2 mm_3218) from methanosarcina mazei. Phyre2 PDB 3g12 chain A Region: 2 - 115 Aligned: 110 Modelled: 112 Confidence: 99.8% Identity: 21% PDB header:lyase Chain: A: PDB Molecule:putative lactoylglutathione lyase; PDBTitle: crystal structure of a putative lactoylglutathione lyase from2 bdellovibrio bacteriovorus Phyre2 PDB 6a4z chain A Region: 3 - 120 Aligned: 118 Modelled: 118 Confidence: 99.8% Identity: 16% PDB header:biosynthetic protein Chain: A: PDB Molecule:chap protein; PDBTitle: oxidase chap Phyre2 PDB 4mym chain A Region: 1 - 121 Aligned: 121 Modelled: 121 Confidence: 99.8% Identity: 18% PDB header:oxidoreductase Chain: A: PDB Molecule:glyoxalase/bleomycin resistance protein/dioxygenase; PDBTitle: crystal structure of a glyoxalase/ bleomycin resistance protein/2 dioxygenase from nocardioides Phyre2 PDB 3fcd chain B Region: 3 - 124 Aligned: 118 Modelled: 122 Confidence: 99.8% Identity: 18% PDB header:lyase Chain: B: PDB Molecule:lyase; PDBTitle: crystal structure of a putative glyoxalase from an2 environmental bacteria Phyre2 PDB 4g6x chain A Region: 3 - 116 Aligned: 113 Modelled: 113 Confidence: 99.8% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:glyoxalase/bleomycin resistance protein/dioxygenase; PDBTitle: crystal structure of glyoxalase/bleomycin resistance protein from2 catenulispora acidiphila. Phyre2 PDB 2pjs chain A domain 1 Region: 3 - 114 Aligned: 111 Modelled: 112 Confidence: 99.8% Identity: 17% Fold: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family: Antibiotic resistance proteins Phyre2 PDB 3rhe chain A Region: 6 - 117 Aligned: 111 Modelled: 112 Confidence: 99.8% Identity: 14% PDB header:oxidoreductase Chain: A: PDB Molecule:nad-dependent benzaldehyde dehydrogenase; PDBTitle: the crystal structure of nad-dependent benzaldehyde dehydrogenase from2 legionella pneumophila Phyre2 PDB 3rri chain B Region: 5 - 122 Aligned: 118 Modelled: 116 Confidence: 99.8% Identity: 16% PDB header:metal binding protein Chain: B: PDB Molecule:glyoxalase/bleomycin resistance protein/dioxygenase; PDBTitle: crystal structure of glyoxalase/bleomycin resistance2 protein/dioxygenase from alicyclobacillus acidocaldarius Phyre2 PDB 5umw chain A Region: 2 - 117 Aligned: 115 Modelled: 116 Confidence: 99.8% Identity: 20% PDB header:tiancimycin-binding protein Chain: A: PDB Molecule:glyoxalase/bleomycin resisance protein/dioxygenase; PDBTitle: crystal structure of tnms2, an antibiotic binding protein from2 streptomyces sp. cb03234 Phyre2 PDB 1qip chain A Region: 2 - 118 Aligned: 116 Modelled: 117 Confidence: 99.8% Identity: 17% Fold: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family: Glyoxalase I (lactoylglutathione lyase) Phyre2 PDB 2kjz chain A Region: 1 - 117 Aligned: 115 Modelled: 117 Confidence: 99.8% Identity: 14% PDB header:unknown function Chain: A: PDB Molecule:atc0852; PDBTitle: solution nmr structure of protein atc0852 from agrobacterium2 tumefaciens. northeast structural genomics consortium (nesg) target3 att2. Phyre2 PDB 3ghj chain A Region: 3 - 116 Aligned: 114 Modelled: 114 Confidence: 99.8% Identity: 18% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative integron gene cassette protein; PDBTitle: crystal structure from the mobile metagenome of halifax harbour sewage2 outfall: integron cassette protein hfx_cass4 Phyre2 PDB 3itw chain A Region: 5 - 115 Aligned: 111 Modelled: 111 Confidence: 99.8% Identity: 17% PDB header:peptide binding protein Chain: A: PDB Molecule:protein tiox; PDBTitle: crystal structure of tiox from micromonospora sp. ml1 Phyre2 1 d2i7ra1 2 c3bt3B_ 3 c4nvsB_ 4 c2r6uB_ 5 c4hc5A_ 6 c3bqxA_ 7 c3r6aB_ 8 c3g12A_ 9 c6a4zA_ 10 c4mymA_ 11 c3fcdB_ 12 c4g6xA_ 13 d2pjsa1 14 c3rheA_ 15 c3rriB_ 16 c5umwA_ 17 d1qipa_ 18 c2kjzA_ 19 c3ghjA_ 20 c3itwA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158