1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		L	L	S	R	R	T	K	T	I	V	V	C	T	L	V	C	M	A	R	L	N	V	Y	V	P	D	E	L	A	E	R	A	R	A	R	G	L	N	V	S	A	L	T	Q	A	A	I	S	A	E	L	E	N	S	A	T	D	A	W	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?													?														?	?																				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.
Sequence		E	G	L	E	P	R	S	T	G	A	R	H	D	D	V	L	G	A	I	D	A	A	R	D	E	F	E	A
Secondary structure
SS confidence
Disorder						?	?	?	?	?	?	?	?	?									?			?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 28%) Alpha helix ( 81%) Beta strand ( 0%)

Rank Aligned region

PDB 5yrz chain C Region: 19 - 50 Aligned: 32 Modelled: 32 Confidence: 83.8% Identity: 25% PDB header:antitoxin/hydrolase Chain: C: PDB Molecule:hicb; PDBTitle: toxin-antitoxin complex from streptococcus pneumoniae Phyre2 PDB 4p7d chain A Region: 19 - 51 Aligned: 33 Modelled: 33 Confidence: 69.5% Identity: 12% PDB header:toxin Chain: A: PDB Molecule:antitoxin hicb3; PDBTitle: antitoxin hicb3 crystal structure Phyre2 PDB 6g1n chain B Region: 19 - 51 Aligned: 33 Modelled: 33 Confidence: 62.4% Identity: 27% PDB header:antitoxin Chain: B: PDB Molecule:antitoxin hicb; PDBTitle: crystal structure of the burkholderia pseudomallei antitoxin hicb Phyre2 PDB 6a6x chain C Region: 26 - 54 Aligned: 29 Modelled: 29 Confidence: 37.9% Identity: 62% PDB header:toxin Chain: C: PDB Molecule:antitoxin maze7; PDBTitle: the crystal structure of the mtb maze-mazf-mt9 complex Phyre2 PDB 5x3t chain A Region: 22 - 49 Aligned: 28 Modelled: 28 Confidence: 26.8% Identity: 43% PDB header:antitoxin/toxin Chain: A: PDB Molecule:antitoxin vapb26; PDBTitle: vapbc from mycobacterium tuberculosis Phyre2 PDB 3qd5 chain B Region: 29 - 86 Aligned: 56 Modelled: 58 Confidence: 24.4% Identity: 23% PDB header:isomerase Chain: B: PDB Molecule:putative ribose-5-phosphate isomerase; PDBTitle: crystal structure of a putative ribose-5-phosphate isomerase from2 coccidioides immitis solved by combined iodide ion sad and mr Phyre2 PDB 2k5j chain B Region: 17 - 53 Aligned: 37 Modelled: 37 Confidence: 23.1% Identity: 27% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein yiif; PDBTitle: solution structure of protein yiif from shigella flexneri2 serotype 5b (strain 8401) . northeast structural genomics3 consortium target sft1 Phyre2 PDB 2ca9 chain B Region: 17 - 65 Aligned: 46 Modelled: 49 Confidence: 23.0% Identity: 26% PDB header:transcription Chain: B: PDB Molecule:putative nickel-responsive regulator; PDBTitle: apo-nikr from helicobacter pylori in closed trans-2 conformation Phyre2 PDB 2bj3 chain D Region: 17 - 65 Aligned: 46 Modelled: 49 Confidence: 20.2% Identity: 24% PDB header:transcription Chain: D: PDB Molecule:nickel responsive regulator; PDBTitle: nikr-apo Phyre2 PDB 2vvp chain A domain 1 Region: 29 - 88 Aligned: 58 Modelled: 60 Confidence: 19.4% Identity: 19% Fold: Ribose/Galactose isomerase RpiB/AlsB Superfamily: Ribose/Galactose isomerase RpiB/AlsB Family: Ribose/Galactose isomerase RpiB/AlsB Phyre2 PDB 1q5v chain B Region: 17 - 52 Aligned: 36 Modelled: 36 Confidence: 17.5% Identity: 28% PDB header:transcription Chain: B: PDB Molecule:nickel responsive regulator; PDBTitle: apo-nikr Phyre2 PDB 1b4a chain A Region: 26 - 52 Aligned: 24 Modelled: 27 Confidence: 12.6% Identity: 50% PDB header:repressor Chain: A: PDB Molecule:arginine repressor; PDBTitle: structure of the arginine repressor from bacillus stearothermophilus Phyre2 PDB 2k29 chain A Region: 17 - 41 Aligned: 25 Modelled: 25 Confidence: 12.4% Identity: 40% PDB header:transcription Chain: A: PDB Molecule:antitoxin relb; PDBTitle: structure of the dbd domain of e. coli antitoxin relb Phyre2 PDB 3e38 chain A Region: 25 - 43 Aligned: 19 Modelled: 19 Confidence: 11.0% Identity: 32% PDB header:hydrolase Chain: A: PDB Molecule:two-domain protein containing predicted php-like metal- PDBTitle: crystal structure of a two-domain protein containing predicted php-2 like metal-dependent phosphoesterase (bvu_3505) from bacteroides3 vulgatus atcc 8482 at 2.20 a resolution Phyre2 PDB 2p5k chain A domain 1 Region: 26 - 51 Aligned: 23 Modelled: 26 Confidence: 10.8% Identity: 39% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Arginine repressor (ArgR), N-terminal DNA-binding domain Phyre2 PDB 4lfn chain D Region: 29 - 81 Aligned: 51 Modelled: 53 Confidence: 10.0% Identity: 22% PDB header:isomerase Chain: D: PDB Molecule:galactose-6-phosphate isomerase subunit b; PDBTitle: crystal structure of d-galactose-6-phosphate isomerase in complex with2 d-ribulose Phyre2 PDB 1v0d chain A Region: 59 - 68 Aligned: 10 Modelled: 10 Confidence: 9.9% Identity: 60% Fold: His-Me finger endonucleases Superfamily: His-Me finger endonucleases Family: Caspase-activated DNase, CAD (DffB, DFF40) Phyre2 PDB 1v0d chain A Region: 59 - 68 Aligned: 10 Modelled: 10 Confidence: 9.9% Identity: 60% PDB header:hydrolase Chain: A: PDB Molecule:dna fragmentation factor 40 kda subunit; PDBTitle: crystal structure of caspase-activated dnase (cad) Phyre2 PDB 6mu0 chain A Region: 29 - 85 Aligned: 54 Modelled: 57 Confidence: 9.8% Identity: 24% PDB header:isomerase Chain: A: PDB Molecule:probable ribose-5-phosphate isomerase b; PDBTitle: crystal structure of ribose-5-phosphate isomerase b from mycoplasma2 genitalium with bound ribulose-5-phosphate Phyre2 PDB 2k9i chain B Region: 19 - 53 Aligned: 35 Modelled: 35 Confidence: 8.7% Identity: 40% PDB header:dna binding protein Chain: B: PDB Molecule:uncharacterized protein orf56; PDBTitle: nmr structure of plasmid copy control protein orf56 from sulfolobus2 islandicus Phyre2 1 c5yrzC_ 2 c4p7dA_ 3 c6g1nB_ 4 c6a6xC_ 5 c5x3tA_ 6 c3qd5B_ 7 c2k5jB_ 8 c2ca9B_ 9 c2bj3D_ 10 d2vvpa1 11 c1q5vB_ 12 c1b4aA_ 13 c2k29A_ 14 c3e38A_ 15 d2p5ka1 16 c4lfnD_ 17 d1v0da_ 18 c1v0dA_ 19 c6mu0A_ 20 c2k9iB_ 21 22 23 24 25 26 27 28 29 30 31 32 33