Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD0555_(menD)_646301_647965
DateFri Jul 26 01:50:10 BST 2019
Unique Job IDc9fda3024501ccb4
SequenceVNPSTTQARV ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:56.660 Y:83.518 Z:56.270
Model (left) based on template c5essB_
Top template information
PDB header:transferase
Chain: B: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
PDBTitle: crystal structure of m. tuberculosis mend bound to mg2+ and covalent2 intermediate i (a thdp and decarboxylated 2-oxoglutarate adduct)
Confidence and coverage
Confidence:100.0% Coverage: 97%
537 residues ( 97% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c5essB_



100.0 100
PDB header:transferase
Chain: B: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
PDBTitle: crystal structure of m. tuberculosis mend bound to mg2+ and covalent2 intermediate i (a thdp and decarboxylated 2-oxoglutarate adduct)
2c2x7jA_



100.0 32
PDB header:transferase
Chain: A: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene
PDBTitle: structure of the menaquinone biosynthesis protein mend from2 bacillus subtilis
3c1powA_



100.0 15
PDB header:oxidoreductase(oxygen as acceptor)
Chain: A: PDB Molecule:pyruvate oxidase;
PDBTitle: the refined structures of a stabilized mutant and of wild-type2 pyruvate oxidase from lactobacillus plantarum
4c3ey9B_



100.0 17
PDB header:oxidoreductase
Chain: B: PDB Molecule:pyruvate dehydrogenase [cytochrome];
PDBTitle: structural basis for membrane binding and catalytic activation of the2 peripheral membrane enzyme pyruvate oxidase from escherichia coli
5c2djiA_



100.0 13
PDB header:oxidoreductase
Chain: A: PDB Molecule:pyruvate oxidase;
PDBTitle: crystal structure of pyruvate oxidase from aerococcus2 viridans containing fad
6c4rjjB_



100.0 19
PDB header:lyase
Chain: B: PDB Molecule:acetolactate synthase;
PDBTitle: acetolactate synthase from bacillus subtilis bound to thdp - crystal2 form ii
7c2jlaD_



100.0 28
PDB header:transferase
Chain: D: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene
PDBTitle: crystal structure of e.coli mend, 2-succinyl-5-enolpyruvyl-2 6-hydroxy-3-cyclohexadiene-1-carboxylate synthase - semet3 protein
8c2pgnA_



100.0 16
PDB header:hydrolase
Chain: A: PDB Molecule:cyclohexane-1,2-dione hydrolase (cdh);
PDBTitle: the crystal structure of fad and thdp-dependent cyclohexane-1,2-dione2 hydrolase in complex with cyclohexane-1,2-dione
9c1yi1A_



100.0 17
PDB header:transferase
Chain: A: PDB Molecule:acetolactate synthase;
PDBTitle: crystal structure of arabidopsis thaliana acetohydroxyacid synthase in2 complex with a sulfonylurea herbicide, tribenuron methyl
10c2panF_



100.0 17
PDB header:lyase
Chain: F: PDB Molecule:glyoxylate carboligase;
PDBTitle: crystal structure of e. coli glyoxylate carboligase
11c1ozhD_



100.0 19
PDB header:lyase
Chain: D: PDB Molecule:acetolactate synthase, catabolic;
PDBTitle: the crystal structure of klebsiella pneumoniae acetolactate2 synthase with enzyme-bound cofactor and with an unusual3 intermediate.
12c4k9qB_



100.0 20
PDB header:lyase
Chain: B: PDB Molecule:benzoylformate decarboxylase;
PDBTitle: the crystal structure of benzoylformate decarboxylase from2 polynucleobacter necessarius
13c1t9dB_



100.0 19
PDB header:transferase
Chain: B: PDB Molecule:acetolactate synthase, mitochondrial;
PDBTitle: crystal structure of yeast acetohydroxyacid synthase in complex with a2 sulfonylurea herbicide, metsulfuron methyl
14c2v3wC_



100.0 16
PDB header:lyase
Chain: C: PDB Molecule:benzoylformate decarboxylase;
PDBTitle: crystal structure of the benzoylformate decarboxylase variant l461a2 from pseudomonas putida
15c2ag1A_



100.0 16
PDB header:lyase
Chain: A: PDB Molecule:benzaldehyde lyase;
PDBTitle: crystal structure of benzaldehyde lyase (bal)- semet
16c5ahkB_



100.0 17
PDB header:transferase
Chain: B: PDB Molecule:acetolactate synthase ii, large subunit;
PDBTitle: crystal structure of acetohydroxy acid synthase pf5 from2 pseudomonas protegens
17c1zpdA_



100.0 18
PDB header:alcohol fermentation
Chain: A: PDB Molecule:pyruvate decarboxylase;
PDBTitle: pyruvate decarboxylase from zymomonas mobilis
18c3lq1A_



100.0 31
PDB header:transferase
Chain: A: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
PDBTitle: crystal structure of 2-succinyl-6-hydroxy-2,4-cyclohexadiene 1-2 carboxylic acid synthase/2-oxoglutarate decarboxylase from listeria3 monocytogenes str. 4b f2365
19c3eyaE_



100.0 18
PDB header:oxidoreductase
Chain: E: PDB Molecule:pyruvate dehydrogenase [cytochrome];
PDBTitle: structural basis for membrane binding and catalytic2 activation of the peripheral membrane enzyme pyruvate3 oxidase from escherichia coli
20c2ji6B_



100.0 16
PDB header:lyase
Chain: B: PDB Molecule:oxalyl-coa decarboxylase;
PDBTitle: x-ray structure of oxalyl-coa decarboxylase in complex with 3-deaza-2 thdp and oxalyl-coa
21c1jscA_



not modelled 100.0 20
PDB header:lyase
Chain: A: PDB Molecule:acetohydroxy-acid synthase;
PDBTitle: crystal structure of the catalytic subunit of yeast2 acetohydroxyacid synthase: a target for herbicidal3 inhibitors
22c2vbiF_



not modelled 100.0 16
PDB header:lyase
Chain: F: PDB Molecule:pyruvate decarboxylase;
PDBTitle: holostructure of pyruvate decarboxylase from acetobacter pasteurianus
23c4q9dA_



not modelled 100.0 20
PDB header:lyase
Chain: A: PDB Molecule:benzoylformate decarboxylase;
PDBTitle: x-ray structure of a putative thiamin diphosphate-dependent enzyme2 isolated from mycobacterium smegmatis
24c2q27B_



not modelled 100.0 18
PDB header:lyase
Chain: B: PDB Molecule:oxalyl-coa decarboxylase;
PDBTitle: crystal structure of oxalyl-coa decarboxylase from escherichia coli
25c2vbgB_



not modelled 100.0 15
PDB header:lyase
Chain: B: PDB Molecule:branched-chain alpha-ketoacid decarboxylase;
PDBTitle: the complex structure of the branched-chain keto acid2 decarboxylase (kdca) from lactococcus lactis with 2r-1-3 hydroxyethyl-deazathdp
26c1upaC_



not modelled 100.0 20
PDB header:synthase
Chain: C: PDB Molecule:carboxyethylarginine synthase;
PDBTitle: carboxyethylarginine synthase from streptomyces2 clavuligerus (semet structure)
27c1ovmC_



not modelled 100.0 16
PDB header:lyase
Chain: C: PDB Molecule:indole-3-pyruvate decarboxylase;
PDBTitle: crystal structure of indolepyruvate decarboxylase from2 enterobacter cloacae
28c2w93A_



not modelled 100.0 14
PDB header:lyase
Chain: A: PDB Molecule:pyruvate decarboxylase isozyme 1;
PDBTitle: crystal structure of the saccharomyces cerevisiae pyruvate2 decarboxylase variant e477q in complex with the surrogate pyruvamide
29c2nxwB_



not modelled 100.0 15
PDB header:lyase
Chain: B: PDB Molecule:phenyl-3-pyruvate decarboxylase;
PDBTitle: crystal structure of phenylpyruvate decarboxylase of azospirillum2 brasilense
30d1q6za2



not modelled 100.0 20
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
31d2djia2



not modelled 100.0 16
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
32d1ozha2



not modelled 100.0 24
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
33d1ybha2



not modelled 100.0 25
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
34d1zpda2



not modelled 100.0 20
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
35d2ji7a2



not modelled 100.0 24
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
36d2ihta2



not modelled 100.0 22
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
37d1t9ba2



not modelled 100.0 25
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
38d1pvda2



not modelled 100.0 16
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
39d2ez9a2



not modelled 100.0 18
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
40d1ovma2



not modelled 100.0 17
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase Pyr module
41d2ez9a3



not modelled 100.0 14
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
42d1ybha3



not modelled 100.0 13
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
43d1ozha3



not modelled 100.0 17
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
44d2djia3



not modelled 100.0 13
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
45d1t9ba3



not modelled 100.0 17
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
46d1pvda3



not modelled 100.0 17
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
47d1ovma3



not modelled 100.0 20
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
48d1zpda3



not modelled 100.0 17
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
49d2ihta3



not modelled 100.0 22
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
50d1q6za3



not modelled 100.0 17
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
51d2ji7a3



not modelled 100.0 14
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
52d1jsca3



not modelled 100.0 20
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Pyruvate oxidase and decarboxylase PP module
53c5b46B_



not modelled 99.8 14
PDB header:oxidoreductase
Chain: B: PDB Molecule:2-oxoacid--ferredoxin oxidoreductase beta subunit;
PDBTitle: 2-oxoacid:ferredoxin oxidoreductase 2 from sulfolobus tokodai - ligand2 free form
54c6n2oB_



not modelled 99.8 13
PDB header:oxidoreductase
Chain: B: PDB Molecule:pyruvate ferredoxin/flavodoxin oxidoreductase, beta
PDBTitle: 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus2 with 2-oxoglutarate, coenzyme a and succinyl-coa bound
55c4wbxC_



not modelled 99.7 14
PDB header:oxidoreductase
Chain: C: PDB Molecule:2-keto acid:ferredoxin oxidoreductase subunit alpha;
PDBTitle: conserved hypothetical protein pf1771 from pyrococcus furiosus solved2 by sulfur sad using swiss light source data
56d2c42a1



not modelled 99.6 13
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:PFOR Pyr module
57c5c4iC_



not modelled 99.6 12
PDB header:oxidoreductase
Chain: C: PDB Molecule:oxalate oxidoreductase subunit beta;
PDBTitle: structure of an oxalate oxidoreductase
58c6n2nA_



not modelled 99.6 20
PDB header:oxidoreductase
Chain: A: PDB Molecule:pyruvate flavodoxin/ferredoxin oxidoreductase domain
PDBTitle: crystal structure of 2-oxoglutarate:ferredoxin oxidoreductase from2 magnetococcus marinus
59c5c4iA_



not modelled 99.5 12
PDB header:oxidoreductase
Chain: A: PDB Molecule:oxalate oxidoreductase subunit alpha;
PDBTitle: structure of an oxalate oxidoreductase
60d2ez9a1



not modelled 99.4 13
Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
61d2ji7a1



not modelled 99.4 11
Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
62d2djia1



not modelled 99.4 10
Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
63c5b47A_



not modelled 99.4 18
PDB header:oxidoreductase
Chain: A: PDB Molecule:2-oxoacid--ferredoxin oxidoreductase alpha subunit;
PDBTitle: 2-oxoacid:ferredoxin oxidoreductase 2 from sulfolobus tokodai -2 pyruvate complex
64d2bfda1



not modelled 99.4 17
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Branched-chain alpha-keto acid dehydrogenase PP module
65c5b48A_



not modelled 99.4 22
PDB header:oxidoreductase
Chain: A: PDB Molecule:2-oxoacid--ferredoxin oxidoreductase alpha subunit;
PDBTitle: 2-oxoacid:ferredoxin oxidoreductase 1 from sulfolobus tokodai
66d1w85a_



not modelled 99.4 19
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Branched-chain alpha-keto acid dehydrogenase PP module
67d2r8oa2



not modelled 99.4 16
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:TK-like PP module
68d1umda_



not modelled 99.3 17
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Branched-chain alpha-keto acid dehydrogenase PP module
69d1ybha1



not modelled 99.3 14
Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
70d2ozla1



not modelled 99.3 17
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Branched-chain alpha-keto acid dehydrogenase PP module
71d1gpua1



not modelled 99.2 17
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:TK-like PP module
72d1r9ja2



not modelled 99.2 14
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:TK-like PP module
73d1t9ba1



not modelled 99.2 15
Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
74c6cipD_



not modelled 99.2 12
PDB header:oxidoreductase
Chain: D: PDB Molecule:pyruvate-ferredoxin oxidoreductase;
PDBTitle: pyruvate:ferredoxin oxidoreductase from moorella thermoacetica with2 acetyl-tpp bound
75d1ozha1



not modelled 99.2 13
Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
76d1itza1



not modelled 99.2 16
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:TK-like PP module
77c2c3yA_



not modelled 99.2 12
PDB header:oxidoreductase
Chain: A: PDB Molecule:pyruvate-ferredoxin oxidoreductase;
PDBTitle: crystal structure of the radical form of2 pyruvate:ferredoxin oxidoreductase from desulfovibrio3 africanus
78c1yd7A_



not modelled 99.2 15
PDB header:oxidoreductase
Chain: A: PDB Molecule:2-keto acid:ferredoxin oxidoreductase subunit alpha;
PDBTitle: conserved hypothetical protein pfu-1647980-001 from pyrococcus2 furiosus
79d2ihta1



not modelled 99.2 13
Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
80c3mosA_



not modelled 99.1 18
PDB header:transferase
Chain: A: PDB Molecule:transketolase;
PDBTitle: the structure of human transketolase
81d1q6za1



not modelled 99.1 13
Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
82c3m7iA_



not modelled 99.1 19
PDB header:transferase
Chain: A: PDB Molecule:transketolase;
PDBTitle: crystal structure of transketolase in complex with thiamine2 diphosphate, ribose-5-phosphate(pyranose form) and magnesium ion
83d1zpda1



not modelled 99.1 12
Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
84c5nd5A_



not modelled 99.1 18
PDB header:transferase
Chain: A: PDB Molecule:transketolase;
PDBTitle: crystal structure of transketolase from chlamydomonas reinhardtii in2 complex with tpp and mg2+
85c2o1xA_



not modelled 99.0 21
PDB header:transferase
Chain: A: PDB Molecule:1-deoxy-d-xylulose-5-phosphate synthase;
PDBTitle: 1-deoxy-d-xylulose 5-phosphate synthase (dxs) from deinococcus2 radiodurans
86c3rimA_



not modelled 99.0 13
PDB header:transferase
Chain: A: PDB Molecule:transketolase;
PDBTitle: crystal structure of mycobacterium tuberculosis transketolase2 (rv1449c)
87c2r8pA_



not modelled 99.0 17
PDB header:transferase
Chain: A: PDB Molecule:transketolase 1;
PDBTitle: transketolase from e. coli in complex with substrate d-fructose-6-2 phosphate
88c4c7vA_



not modelled 99.0 21
PDB header:transferase
Chain: A: PDB Molecule:transketolase;
PDBTitle: apo transketolase from lactobacillus salivarius at 2.2a resolution
89c3uk1A_



not modelled 99.0 16
PDB header:transferase
Chain: A: PDB Molecule:transketolase;
PDBTitle: crystal structure of a transketolase from burkholderia thailandensis2 with an oxidized cysteinesulfonic acid in the active site
90d1qs0a_



not modelled 99.0 18
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Branched-chain alpha-keto acid dehydrogenase PP module
91c5hgxA_



not modelled 99.0 16
PDB header:transferase
Chain: A: PDB Molecule:transketolase;
PDBTitle: crystal structure of transketolase mutant - h261f from pichia stipitis
92c3hylB_



not modelled 99.0 15
PDB header:transferase
Chain: B: PDB Molecule:transketolase;
PDBTitle: crystal structure of transketolase from bacillus anthracis
93c1itzC_



not modelled 99.0 15
PDB header:transferase
Chain: C: PDB Molecule:transketolase;
PDBTitle: maize transketolase in complex with tpp
94c2o1sC_



not modelled 99.0 25
PDB header:transferase
Chain: C: PDB Molecule:1-deoxy-d-xylulose-5-phosphate synthase;
PDBTitle: 1-deoxy-d-xylulose 5-phosphate synthase (dxs) from2 escherichia coli
95d1ovma1



not modelled 99.0 5
Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
96c2e6kB_



not modelled 98.9 22
PDB header:transferase
Chain: B: PDB Molecule:transketolase;
PDBTitle: x-ray structure of thermus thermopilus hb8 tt0505
97c1tkcA_



not modelled 98.9 18
PDB header:transferase
Chain: A: PDB Molecule:transketolase;
PDBTitle: specificity of coenzyme binding in thiamin diphosphate2 dependent enzymes: crystal structures of yeast3 transketolase in complex with analogs of thiamin4 diphosphate
98c5vrbB_



not modelled 98.9 14
PDB header:transferase
Chain: B: PDB Molecule:transketolase;
PDBTitle: crystal structure of a transketolase from neisseria gonorrhoeae
99c1r9jB_



not modelled 98.8 13
PDB header:transferase
Chain: B: PDB Molecule:transketolase;
PDBTitle: transketolase from leishmania mexicana
100d2c42a2



not modelled 98.8 12
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:PFOR PP module
101c2g28A_



not modelled 98.8 13
PDB header:oxidoreductase
Chain: A: PDB Molecule:pyruvate dehydrogenase e1 component;
PDBTitle: e. coli pyruvate dehydrogenase h407a variant2 phosphonolactylthiamin diphosphate complex
102c6ouwA_



not modelled 98.8 24
PDB header:transferase
Chain: A: PDB Molecule:1-deoxy-d-xylulose-5-phosphate synthase;
PDBTitle: 1-deoxy-d-xylulose 5-phosphate synthase (dxps) from deinococcus2 radiodurans with enamine intermediate bound
103d1pvda1



not modelled 98.7 10
Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
104d2ieaa2



not modelled 98.7 14
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:TK-like PP module
105c3komB_



not modelled 98.7 14
PDB header:transferase
Chain: B: PDB Molecule:transketolase;
PDBTitle: crystal structure of apo transketolase from francisella tularensis
106c4qoyC_



not modelled 98.6 15
PDB header:oxidoreductase
Chain: C: PDB Molecule:pyruvate dehydrogenase e1 component;
PDBTitle: novel binding motif and new flexibility revealed by structural2 analysis of a pyruvate dehydrogenase-dihydrolipoyl acetyltransferase3 sub-complex from the escherichia coli pyruvate dehydrogenase multi-4 enzyme complex
107c3ahhA_



not modelled 98.4 12
PDB header:lyase
Chain: A: PDB Molecule:xylulose 5-phosphate/fructose 6-phosphate phosphoketolase;
PDBTitle: h142a mutant of phosphoketolase from bifidobacterium breve complexed2 with acetyl thiamine diphosphate
108c5ol2D_



not modelled 98.3 17
PDB header:flavoprotein
Chain: D: PDB Molecule:electron transfer flavoprotein large subunit;
PDBTitle: the electron transferring flavoprotein/butyryl-coa dehydrogenase2 complex from clostridium difficile
109c3cf4G_



not modelled 98.1 16
PDB header:oxidoreductase
Chain: G: PDB Molecule:acetyl-coa decarboxylase/synthase epsilon subunit;
PDBTitle: structure of the codh component of the m. barkeri acds complex
110d1gpua2



not modelled 97.5 17
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:TK-like Pyr module
111c2yicC_



not modelled 97.5 12
PDB header:lyase
Chain: C: PDB Molecule:2-oxoglutarate decarboxylase;
PDBTitle: crystal structure of the suca domain of mycobacterium smegmatis2 alpha-ketoglutarate decarboxylase (triclinic form)
112d2r8oa1



not modelled 97.4 18
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:TK-like Pyr module
113c2jgdA_



not modelled 97.4 12
PDB header:oxidoreductase
Chain: A: PDB Molecule:2-oxoglutarate dehydrogenase e1 component;
PDBTitle: e. coli 2-oxoglutarate dehydrogenase (e1o)
114d1r9ja1



not modelled 97.1 17
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:TK-like Pyr module
115d1itza2



not modelled 97.0 18
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:TK-like Pyr module
116c4l2iA_



not modelled 96.7 11
PDB header:electron transport
Chain: A: PDB Molecule:electron transfer flavoprotein alpha subunit;
PDBTitle: electron transferring flavoprotein of acidaminococcus fermentans:2 towards a mechanism of flavin-based electron bifurcation
117c2xt6B_



not modelled 95.4 13
PDB header:lyase
Chain: B: PDB Molecule:2-oxoglutarate decarboxylase;
PDBTitle: crystal structure of mycobacterium smegmatis alpha-ketoglutarate2 decarboxylase homodimer (orthorhombic form)
118c2bp7F_



not modelled 92.1 15
PDB header:oxidoreductase
Chain: F: PDB Molecule:2-oxoisovalerate dehydrogenase beta subunit;
PDBTitle: new crystal form of the pseudomonas putida branched-chain2 dehydrogenase (e1)
119c1olsB_



not modelled 91.9 11
PDB header:oxidoreductase
Chain: B: PDB Molecule:2-oxoisovalerate dehydrogenase beta subunit;
PDBTitle: roles of his291-alpha and his146-beta' in the reductive acylation2 reaction catalyzed by human branched-chain alpha-ketoacid3 dehydrogenase
120d1w85b1



not modelled 85.9 20
Fold:Thiamin diphosphate-binding fold (THDP-binding)
Superfamily:Thiamin diphosphate-binding fold (THDP-binding)
Family:Branched-chain alpha-keto acid dehydrogenase Pyr module

Binding site prediction 

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Transmembrane helix prediction 

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