1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	T	H	A	V	I	I	T	Y	L	R	D	Q	T	Q	P	A	V	D	A	I	G	G	F	Y	R	T	C	V	L	T	G	K	A	L	V	R	R	P	F	H	W	R	E	A	I	E	Q	G	W	F	I	T	S	V	S	L	L	P
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	L	A	V	S	I	P	L	T	V	L	I	I	F	T	L	N	I	L	L	A	E	F	G	A	A	D	I	S	G	A	G	A	A	L	G	A	V	T	Q	L	G	P	L	T	T	V	L	V	I	A	G	A	G	A	T	A	I	C	A
Secondary structure
SS confidence
Disorder																								?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	L	G	A	R	T	I	R	E	E	I	D	A	M	E	V	L	G	I	D	P	I	H	R	L	V	V	P	R	V	V	A	A	T	I	V	A	A	L	L	N	G	A	V	I	T	I	G	L	V	G	G	F	V	F	S	V	F	I	Q
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		H	V	S	A	G	A	Y	V	G	T	L	T	L	V	T	G	L	P	E	V	I	I	S	V	V	K	S	A	T	F	G	L	I	A	G	L	V	G	C	Y	R	G	L	T	T	K	G	G	P	K	G	V	G	T	A	V	N	E	T	L
Secondary structure
SS confidence
Disorder																																														?			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.
Sequence		V	L	C	V	I	A	L	F	A	T	N	V	V	L	T	T	I	G	V	R	F	G	T	G	H
Secondary structure
SS confidence
Disorder																						?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 5%) Alpha helix ( 88%) Beta strand ( 0%) TM helix ( 62%) (View membrane topology prediction)

Rank Aligned region

PDB 6ic4 chain H Region: 5 - 258 Aligned: 253 Modelled: 254 Confidence: 100.0% Identity: 22% PDB header:protein transport Chain: H: PDB Molecule:abc transporter permease; PDBTitle: cryo-em structure of the a. baumannii mla complex at 8.7 a resolution Phyre2 PDB 5x5y chain G Region: 51 - 168 Aligned: 115 Modelled: 118 Confidence: 74.4% Identity: 14% PDB header:membrane protein Chain: G: PDB Molecule:uncharacterized protein; PDBTitle: a membrane protein complex Phyre2 PDB 5l75 chain F Region: 51 - 168 Aligned: 116 Modelled: 118 Confidence: 64.1% Identity: 16% PDB header:transport protein Chain: F: PDB Molecule:fig000988: predicted permease; PDBTitle: a protein structure Phyre2 PDB 6mjp chain G Region: 49 - 168 Aligned: 118 Modelled: 120 Confidence: 56.9% Identity: 13% PDB header:lipid transport Chain: G: PDB Molecule:lps export abc transporter permease lptg; PDBTitle: lptb(e163q)fgc from vibrio cholerae Phyre2 PDB 5l75 chain G Region: 117 - 162 Aligned: 46 Modelled: 46 Confidence: 37.2% Identity: 17% PDB header:transport protein Chain: G: PDB Molecule:fig000906: predicted permease; PDBTitle: a protein structure Phyre2 PDB 5x5y chain F Region: 51 - 168 Aligned: 116 Modelled: 118 Confidence: 22.6% Identity: 15% PDB header:membrane protein Chain: F: PDB Molecule:uncharacterized protein; PDBTitle: a membrane protein complex Phyre2 PDB 5xu1 chain M Region: 101 - 221 Aligned: 115 Modelled: 121 Confidence: 22.4% Identity: 16% PDB header:transport protein Chain: M: PDB Molecule:abc transporter permeae; PDBTitle: structure of a non-canonical abc transporter from streptococcus2 pneumoniae r6 Phyre2 PDB 6qvc chain B Region: 56 - 263 Aligned: 203 Modelled: 208 Confidence: 21.5% Identity: 14% PDB header:membrane protein Chain: B: PDB Molecule:chloride channel protein 1; PDBTitle: cryoem structure of the human clc-1 chloride channel, cbs state 1 Phyre2 PDB 2haf chain A domain 1 Region: 132 - 141 Aligned: 10 Modelled: 10 Confidence: 19.0% Identity: 50% Fold: VC0467-like Superfamily: VC0467-like Family: VC0467-like Phyre2 PDB 5gha chain F Region: 132 - 141 Aligned: 10 Modelled: 10 Confidence: 17.7% Identity: 40% PDB header:transferase/transport protein Chain: F: PDB Molecule:sulfur carrier ttub; PDBTitle: sulfur transferase ttua in complex with sulfur carrier ttub Phyre2 PDB 6mjp chain F Region: 51 - 168 Aligned: 107 Modelled: 118 Confidence: 16.4% Identity: 18% PDB header:lipid transport Chain: F: PDB Molecule:fig000988: predicted permease; PDBTitle: lptb(e163q)fgc from vibrio cholerae Phyre2 PDB 2m67 chain A Region: 204 - 220 Aligned: 17 Modelled: 17 Confidence: 15.6% Identity: 6% PDB header:transport protein Chain: A: PDB Molecule:merf; PDBTitle: full-length mercury transporter protein merf in lipid bilayer2 membranes Phyre2 PDB 2yvx chain D Region: 28 - 181 Aligned: 115 Modelled: 126 Confidence: 14.2% Identity: 22% PDB header:transport protein Chain: D: PDB Molecule:mg2+ transporter mgte; PDBTitle: crystal structure of magnesium transporter mgte Phyre2 PDB 2aj2 chain A Region: 132 - 141 Aligned: 10 Modelled: 10 Confidence: 14.0% Identity: 50% PDB header:unknown function Chain: A: PDB Molecule:hypothetical upf0301 protein vc0467; PDBTitle: x-ray crystal structure of protein vc0467 from vibrio2 cholerae. northeast structural genomics consortium target3 vcr8. Phyre2 PDB 6coy chain B Region: 56 - 263 Aligned: 203 Modelled: 208 Confidence: 13.9% Identity: 14% PDB header:transport protein Chain: B: PDB Molecule:chloride channel protein 1; PDBTitle: human clc-1 chloride ion channel, transmembrane domain Phyre2 PDB 2hg5 chain D Region: 149 - 179 Aligned: 31 Modelled: 31 Confidence: 13.3% Identity: 13% PDB header:membrane protein Chain: D: PDB Molecule:kcsa channel; PDBTitle: cs+ complex of a k channel with an amide to ester substitution in the2 selectivity filter Phyre2 PDB 2hv8 chain D Region: 117 - 135 Aligned: 19 Modelled: 19 Confidence: 12.9% Identity: 16% PDB header:protein transport Chain: D: PDB Molecule:rab11 family-interacting protein 3; PDBTitle: crystal structure of gtp-bound rab11 in complex with fip3 Phyre2 PDB 4mig chain C Region: 103 - 123 Aligned: 21 Modelled: 21 Confidence: 12.4% Identity: 29% PDB header:oxidoreductase Chain: C: PDB Molecule:pyranose 2-oxidase; PDBTitle: pyranose 2-oxidase from phanerochaete chrysosporium, recombinant wild2 type Phyre2 PDB 2mfr chain A Region: 143 - 175 Aligned: 33 Modelled: 33 Confidence: 11.9% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:insulin receptor; PDBTitle: solution structure of the transmembrane domain of the insulin receptor2 in micelles Phyre2 PDB 2kn8 chain A Region: 123 - 146 Aligned: 24 Modelled: 24 Confidence: 11.7% Identity: 29% PDB header:protein binding, dna binding protein Chain: A: PDB Molecule:dna cleavage and packaging protein large subunit, ul89; PDBTitle: nmr structure of the c-terminal domain of pul89 Phyre2 1 c6ic4H_ 2 c5x5yG_ 3 c5l75F_ 4 c6mjpG_ 5 c5l75G_ 6 c5x5yF_ 7 c5xu1M_ 8 c6qvcB_ 9 d2hafa1 10 c5ghaF_ 11 c6mjpF_ 12 c2m67A_ 13 c2yvxD_ 14 c2aj2A_ 15 c6coyB_ 16 c2hg5D_ 17 c2hv8D_ 18 c4migC_ 19 c2mfrA_ 20 c2kn8A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43