1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	R	R	R	G	A	R	M	A	A	L	L	A	A	A	A	L	A	L	T	A	C	A	G	S	D	D	K	G	E	P	D	D	G	G	D	R	G	A	S	L	A	T	T	S	D	A	D	W	K	P	V	A	D	I	L	G	R	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?											?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?			?		?	?	?											?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	K	L	N	D	G	S	V	Y	K	I	G	F	A	R	S	D	L	S	V	Q	T	K	G	V	T	V	A	P	A	L	S	L	G	S	W	V	A	F	A	R	T	P	D	G	Q	T	M	L	M	G	D	L	V	V	T	E	D	E	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?																						?	?	?		?	?	?	?								?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	S	V	T	D	A	V	Q	A	G	G	L	Q	Q	T	A	L	H	K	H	L	L	E	Q	S	P	P	I	W	W	T	H	I	A	G	H	G	D	A	A	D	L	A	R	A	V	R	S	A	L	D	A	T	D	T	P	P	P	A	S
Secondary structure
SS confidence
Disorder											?																																											?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	T	S	G	Q	T	S	L	D	L	D	T	A	A	I	D	E	A	L	G	R	S	G	T	I	A	G	G	V	Y	K	F	F	I	A	R	R	D	P	V	T	M	S	G	M	L	I	P	P	S	M	G	L	A	T	A	L	N	F	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?								?	?	?	?	?	?	?	?											?	?					?	?			?		?		?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		P	T	G	N	G	R	A	A	I	N	G	D	F	V	M	T	A	A	E	V	Q	D	V	V	Q	A	L	R	G	G	G	I	D	I	V	A	I	H	N	H	G	F	D	E	Q	P	R	L	F	Y	M	H	F	W	A	E	N	D	A	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.
Sequence		A	L	A	R	T	L	R	A	A	V	D	A	T	A	A	R
Secondary structure
SS confidence
Disorder															?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 28%) Alpha helix ( 28%) Beta strand ( 32%)

Rank Aligned region

PDB 1y7p chain B Region: 120 - 277 Aligned: 142 Modelled: 158 Confidence: 84.9% Identity: 20% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein af1403; PDBTitle: 1.9 a crystal structure of a protein of unknown function2 af1403 from archaeoglobus fulgidus, probable metabolic3 regulator Phyre2 PDB 3o1l chain B Region: 260 - 316 Aligned: 56 Modelled: 56 Confidence: 74.8% Identity: 20% PDB header:hydrolase Chain: B: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pspto_4314)2 from pseudomonas syringae pv. tomato str. dc3000 at 2.20 a resolution Phyre2 PDB 2qmw chain A domain 2 Region: 260 - 313 Aligned: 53 Modelled: 54 Confidence: 72.0% Identity: 9% Fold: Ferredoxin-like Superfamily: ACT-like Family: Phenylalanine metabolism regulatory domain Phyre2 PDB 6avh chain A Region: 204 - 315 Aligned: 102 Modelled: 112 Confidence: 65.8% Identity: 16% PDB header:ligase, plant protein Chain: A: PDB Molecule:gh3.15 acyl acid amido synthetase; PDBTitle: gh3.15 acyl acid amido synthetase Phyre2 PDB 1xod chain A domain 1 Region: 279 - 311 Aligned: 32 Modelled: 33 Confidence: 59.7% Identity: 28% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Enabled/VASP homology 1 domain (EVH1 domain) Phyre2 PDB 2im5 chain C Region: 157 - 213 Aligned: 55 Modelled: 57 Confidence: 58.4% Identity: 18% PDB header:transferase Chain: C: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: crystal structure of nicotinate phosphoribosyltransferase from2 porphyromonas gingivalis Phyre2 PDB 1ddw chain A Region: 279 - 313 Aligned: 35 Modelled: 35 Confidence: 54.9% Identity: 14% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Enabled/VASP homology 1 domain (EVH1 domain) Phyre2 PDB 5l0l chain B Region: 283 - 299 Aligned: 17 Modelled: 17 Confidence: 50.8% Identity: 29% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein lpg0439 Phyre2 PDB 2m3a chain A Region: 42 - 75 Aligned: 34 Modelled: 34 Confidence: 48.9% Identity: 35% PDB header:dna binding protein Chain: A: PDB Molecule:protein knl-2; PDBTitle: nmr solution structure of a myb-like dna binding domain of knl-2 from2 c. elegans Phyre2 PDB 2mda chain B Region: 120 - 183 Aligned: 58 Modelled: 64 Confidence: 43.9% Identity: 9% PDB header:oxidoreductase Chain: B: PDB Molecule:tyrosine 3-monooxygenase; PDBTitle: the solution structure of the regulatory domain of tyrosine2 hydroxylase Phyre2 PDB 5xlm chain B Region: 207 - 239 Aligned: 32 Modelled: 33 Confidence: 42.0% Identity: 25% PDB header:transferase Chain: B: PDB Molecule:serine/threonine-protein kinase pkni; PDBTitle: monomer form of m.tuberculosis pkni sensor domain Phyre2 PDB 4j38 chain A Region: 253 - 271 Aligned: 19 Modelled: 19 Confidence: 41.5% Identity: 26% PDB header:immune system Chain: A: PDB Molecule:outer surface protein e; PDBTitle: structure of borrelia burgdorferi outer surface protein e in complex2 with factor h domains 19-20 Phyre2 PDB 1i7a chain A Region: 279 - 313 Aligned: 35 Modelled: 35 Confidence: 40.4% Identity: 17% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Enabled/VASP homology 1 domain (EVH1 domain) Phyre2 PDB 1evh chain A Region: 280 - 311 Aligned: 32 Modelled: 32 Confidence: 39.5% Identity: 19% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Enabled/VASP homology 1 domain (EVH1 domain) Phyre2 PDB 3n0v chain D Region: 260 - 316 Aligned: 56 Modelled: 57 Confidence: 39.4% Identity: 18% PDB header:hydrolase Chain: D: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pp_0327)2 from pseudomonas putida kt2440 at 2.25 a resolution Phyre2 PDB 2ivf chain B Region: 105 - 151 Aligned: 42 Modelled: 47 Confidence: 33.4% Identity: 24% PDB header:oxidoreductase Chain: B: PDB Molecule:ethylbenzene dehydrogenase beta-subunit; PDBTitle: ethylbenzene dehydrogenase from aromatoleum aromaticum Phyre2 PDB 4yub chain B Region: 157 - 213 Aligned: 57 Modelled: 57 Confidence: 31.8% Identity: 23% PDB header:ligase Chain: B: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: crystal structure of human nicotinic acid phosphoribosyltransferase Phyre2 PDB 6cxd chain A Region: 256 - 299 Aligned: 44 Modelled: 44 Confidence: 31.2% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:peptidase b; PDBTitle: crystal structure of peptidase b from yersinia pestis co92 at 2.75 a2 resolution Phyre2 PDB 4hl7 chain A Region: 157 - 207 Aligned: 49 Modelled: 51 Confidence: 30.0% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: crystal structure of nicotinate phosphoribosyltransferase (target2 nysgr-026035) from vibrio cholerae Phyre2 PDB 3do6 chain B Region: 256 - 316 Aligned: 49 Modelled: 61 Confidence: 28.5% Identity: 20% PDB header:ligase Chain: B: PDB Molecule:formate--tetrahydrofolate ligase; PDBTitle: crystal structure of putative formyltetrahydrofolate synthetase2 (tm1766) from thermotoga maritima at 1.85 a resolution Phyre2 1 c1y7pB_ 2 c3o1lB_ 3 d2qmwa2 4 c6avhA_ 5 d1xoda1 6 c2im5C_ 7 d1ddwa_ 8 c5l0lB_ 9 c2m3aA_ 10 c2mdaB_ 11 c5xlmB_ 12 c4j38A_ 13 d1i7aa_ 14 d1evha_ 15 c3n0vD_ 16 c2ivfB_ 17 c4yubB_ 18 c6cxdA_ 19 c4hl7A_ 20 c3do6B_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99