1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	D	D	E	L	R	G	L	L	A	R	Y	A	R	G	E	L	S	A	D	D	A	R	R	A	I	L	R	Y	P	K	W	R	V	A	E	I	D	G	E	L	E	T	V	A	L	D	D	G	T	P	M	L	I	A	E	S	S	A	S
Secondary structure
SS confidence
Disorder		?	?													?		?	?	?		?																																			?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	G	R	E	Y	S	G	L	E	L	V	R	D	I	A	P	L	V	G	G	L	S	F	D	P	D	E	P	W	G	S	A	F	R	P	G	A	L	P	E	L	Q	N	W	A	R	T	V	E	L	E	D	A	V	A	K	P	G	P	G
Secondary structure
SS confidence
Disorder		?	?	?																																																?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Q	R	D	L	L	Y	E	G	P	W	W	V	A	V	S	P	G	T	G	R	P	A	V	H	R	A	D	G	L	D	V	I	T	I	M	T	A	P	D	A	A	A	T	F	R	R	T	E	R	H	R	G	L	D	V	V	R	L	G	P
Secondary structure
SS confidence
Disorder																								?													?			?	?	?			?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	L	W	G	D	L	A	K	R	S	D	F	D	G	V	R	L	N	P	L	R	P	L	A	Q	L	W	P	P	H	V	P	A	M	L	V	A	G	C	D	P	R	P	N	A	E	P	L	P	A	R	T	V	A	E	I	H	L	W	L
Secondary structure
SS confidence
Disorder																																													?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		D	Q	H	G	A	R	Q	E	K	R	E	L	S	N	R	A	T	P	V	G	E	V	T	V	A	R	A	W	W	N	Y	D	R	R	E	I	A	F	T	R	V	A	P	A	S	D	T	E	G	L	G	S	V	P	S	R	I	L	C	A
Secondary structure
SS confidence
Disorder				?	?	?	?							?	?	?	?																											?	?	?	?	?		?	?										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	K	L	R	Q	S	I	Q	S	K	L	A	G	L	P	R	L	T	W	R	A	D	A	W	H	R	Q	R	A	A	L	A	V	G	W	A	L	E	L	E	K	L	V	C	G	E	R	V	P	F	A	A	L	R	T	P	E	G	A	H
Secondary structure
SS confidence
Disorder												?												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.
Sequence		L	W	H	L	E	P	Q	A	F	T	A	R	A	I	R	K	L	R	D	R	A	A	S	F	R
Secondary structure
SS confidence
Disorder																							?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 15%) Alpha helix ( 41%) Beta strand ( 19%)

Rank Aligned region

PDB 6d0t chain A Region: 60 - 67 Aligned: 8 Modelled: 8 Confidence: 25.8% Identity: 100% PDB header:de novo protein Chain: A: PDB Molecule:bb1; PDBTitle: de novo design of a fluorescence-activating beta barrel - bb1 Phyre2 PDB 2e76 chain D Region: 80 - 132 Aligned: 50 Modelled: 53 Confidence: 18.3% Identity: 30% PDB header:photosynthesis Chain: D: PDB Molecule:cytochrome b6-f complex iron-sulfur subunit; PDBTitle: crystal structure of the cytochrome b6f complex with tridecyl-2 stigmatellin (tds) from m.laminosus Phyre2 PDB 1ysr chain A domain 1 Region: 33 - 93 Aligned: 61 Modelled: 61 Confidence: 18.2% Identity: 25% Fold: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family: Histidine kinase Phyre2 PDB 1iqp chain F Region: 86 - 146 Aligned: 54 Modelled: 61 Confidence: 17.3% Identity: 30% PDB header:replication Chain: F: PDB Molecule:rfcs; PDBTitle: crystal structure of the clamp loader small subunit from2 pyrococcus furiosus Phyre2 PDB 5muu chain I Region: 68 - 82 Aligned: 15 Modelled: 15 Confidence: 16.8% Identity: 67% PDB header:virus Chain: I: PDB Molecule:major outer capsid protein; PDBTitle: dsrna bacteriophage phi6 nucleocapsid Phyre2 PDB 1e5q chain A domain 2 Region: 78 - 172 Aligned: 91 Modelled: 95 Confidence: 15.8% Identity: 26% Fold: FwdE/GAPDH domain-like Superfamily: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family: Homoserine dehydrogenase-like Phyre2 PDB 2jrt chain A Region: 44 - 81 Aligned: 38 Modelled: 38 Confidence: 14.8% Identity: 26% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: nmr solution structure of the protein coded by gene2 rhos4_12090 of rhodobacter sphaeroides. northeast3 structural genomics target rhr5 Phyre2 PDB 2oa4 chain A domain 1 Region: 44 - 81 Aligned: 38 Modelled: 38 Confidence: 14.6% Identity: 24% Fold: DNA/RNA-binding 3-helical bundle Superfamily: TrpR-like Family: SPO1678-like Phyre2 PDB 4lgd chain H Region: 97 - 112 Aligned: 16 Modelled: 16 Confidence: 12.7% Identity: 44% PDB header:signaling protein Chain: H: PDB Molecule:ras association domain family member 5, rassf5; PDBTitle: structural basis for autoactivation of human mst2 kinase and its2 regulation by rassf5 Phyre2 PDB 2p5d chain A Region: 74 - 99 Aligned: 26 Modelled: 26 Confidence: 12.1% Identity: 15% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0310 protein mjecl36; PDBTitle: crystal structure of mjecl36 from methanocaldococcus2 jannaschii dsm 2661 Phyre2 PDB 1jsx chain A Region: 125 - 206 Aligned: 82 Modelled: 82 Confidence: 12.1% Identity: 15% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: Glucose-inhibited division protein B (GidB) Phyre2 PDB 2hd9 chain A domain 1 Region: 73 - 99 Aligned: 27 Modelled: 27 Confidence: 12.1% Identity: 22% Fold: PUA domain-like Superfamily: PUA domain-like Family: Atu2648/PH1033-like Phyre2 PDB 2e74 chain D domain 1 Region: 80 - 132 Aligned: 50 Modelled: 53 Confidence: 10.6% Identity: 30% Fold: ISP domain Superfamily: ISP domain Family: Rieske iron-sulfur protein (ISP) Phyre2 PDB 2ymy chain B Region: 99 - 112 Aligned: 14 Modelled: 14 Confidence: 10.0% Identity: 50% PDB header:apoptosis Chain: B: PDB Molecule:ras association domain-containing protein 5; PDBTitle: structure of the murine nore1-sarah domain Phyre2 PDB 5cws chain F Region: 284 - 309 Aligned: 26 Modelled: 26 Confidence: 9.7% Identity: 35% PDB header:protein transport Chain: F: PDB Molecule:nucleoporin nic96; PDBTitle: crystal structure of the intact chaetomium thermophilum nsp1-nup49-2 nup57 channel nucleoporin heterotrimer bound to its nic96 nuclear3 pore complex attachment site Phyre2 PDB 5cws chain L Region: 284 - 309 Aligned: 26 Modelled: 26 Confidence: 9.7% Identity: 35% PDB header:protein transport Chain: L: PDB Molecule:nucleoporin nic96; PDBTitle: crystal structure of the intact chaetomium thermophilum nsp1-nup49-2 nup57 channel nucleoporin heterotrimer bound to its nic96 nuclear3 pore complex attachment site Phyre2 PDB 2v3c chain C Region: 93 - 157 Aligned: 51 Modelled: 51 Confidence: 9.5% Identity: 25% PDB header:signaling protein Chain: C: PDB Molecule:signal recognition 54 kda protein; PDBTitle: crystal structure of the srp54-srp19-7s.s srp rna complex2 of m. jannaschii Phyre2 PDB 1vhi chain B Region: 88 - 99 Aligned: 12 Modelled: 12 Confidence: 8.8% Identity: 50% Fold: Ferredoxin-like Superfamily: Viral DNA-binding domain Family: Viral DNA-binding domain Phyre2 PDB 5fno chain B Region: 99 - 121 Aligned: 23 Modelled: 23 Confidence: 8.6% Identity: 30% PDB header:oxidoreductase Chain: B: PDB Molecule:manganese lipoxygenase; PDBTitle: manganese lipoxygenase Phyre2 PDB 2px0 chain D Region: 93 - 157 Aligned: 47 Modelled: 47 Confidence: 8.5% Identity: 26% PDB header:biosynthetic protein Chain: D: PDB Molecule:flagellar biosynthesis protein flhf; PDBTitle: crystal structure of flhf complexed with gmppnp/mg(2+) Phyre2 1 c6d0tA_ 2 c2e76D_ 3 d1ysra1 4 c1iqpF_ 5 c5muuI_ 6 d1e5qa2 7 c2jrtA_ 8 d2oa4a1 9 c4lgdH_ 10 c2p5dA_ 11 d1jsxa_ 12 d2hd9a1 13 d2e74d1 14 c2ymyB_ 15 c5cwsF_ 16 c5cwsL_ 17 c2v3cC_ 18 d1vhib_ 19 c5fnoB_ 20 c2px0D_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46