1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	R	Q	A	R	R	H	R	K	R	H	G	D	N	L	F	A	S	L	L	A	R	E	V	A	D	G	S	R	I	V	V	R	G	E	L	F	T	A	F	V	P	F	A	A	R	W	P	V	E	V	H	I	Y	P	N	R	L	V
Secondary structure
SS confidence
Disorder		?	?											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	N	L	T	E	L	N	D	G	E	L	D	E	F	A	R	I	Y	L	D	V	L	Q	R	F	D	R	M	Y	S	S	P	L	P	Y	M	S	A	L	H	Q	F	S	E	V	Q	R	D	G	Y	F	H	V	E	L	M	S	I	R	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.
Sequence		S	A	T	K	L	K	Y	L	A	A	A	E	S	A	M	D	A	F	I	A	D	V	I	P	E	S	V	A	T	R	L	R	E	L	G	P
Secondary structure
SS confidence
Disorder					?																													?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 5%) Alpha helix ( 33%) Beta strand ( 26%)

Rank Aligned region

PDB 1guq chain A domain 2 Region: 2 - 156 Aligned: 154 Modelled: 155 Confidence: 100.0% Identity: 27% Fold: HIT-like Superfamily: HIT-like Family: Hexose-1-phosphate uridylyltransferase Phyre2 PDB 5in3 chain A Region: 2 - 156 Aligned: 154 Modelled: 155 Confidence: 100.0% Identity: 30% PDB header:transferase Chain: A: PDB Molecule:galactose-1-phosphate uridylyltransferase; PDBTitle: crystal structure of glucose-1-phosphate bound nucleotidylated human2 galactose-1-phosphate uridylyltransferase Phyre2 PDB 1gup chain C Region: 2 - 156 Aligned: 154 Modelled: 155 Confidence: 100.0% Identity: 27% PDB header:nucleotidyltransferase Chain: C: PDB Molecule:galactose-1-phosphate uridylyltransferase; PDBTitle: structure of nucleotidyltransferase complexed with udp-2 galactose Phyre2 PDB 1z84 chain A domain 2 Region: 1 - 154 Aligned: 144 Modelled: 154 Confidence: 100.0% Identity: 22% Fold: HIT-like Superfamily: HIT-like Family: Hexose-1-phosphate uridylyltransferase Phyre2 PDB 1zwj chain A Region: 2 - 154 Aligned: 143 Modelled: 153 Confidence: 100.0% Identity: 22% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative galactose-1-phosphate uridyl transferase; PDBTitle: x-ray structure of galt-like protein from arabidopsis thaliana2 at5g18200 Phyre2 PDB 3lb5 chain B Region: 12 - 155 Aligned: 131 Modelled: 144 Confidence: 100.0% Identity: 16% PDB header:cell cycle Chain: B: PDB Molecule:hit-like protein involved in cell-cycle regulation; PDBTitle: crystal structure of hit-like protein involved in cell-cycle2 regulation from bartonella henselae with unknown ligand Phyre2 PDB 3imi chain B Region: 13 - 155 Aligned: 135 Modelled: 143 Confidence: 100.0% Identity: 10% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hit family protein; PDBTitle: 2.01 angstrom resolution crystal structure of a hit family protein2 from bacillus anthracis str. 'ames ancestor' Phyre2 PDB 3o0m chain B Region: 14 - 154 Aligned: 127 Modelled: 141 Confidence: 100.0% Identity: 14% PDB header:hydrolase Chain: B: PDB Molecule:hit family protein; PDBTitle: crystal structure of a zn-bound histidine triad family protein from2 mycobacterium smegmatis Phyre2 PDB 1y23 chain A Region: 13 - 155 Aligned: 135 Modelled: 143 Confidence: 100.0% Identity: 12% Fold: HIT-like Superfamily: HIT-like Family: HIT (HINT, histidine triad) family of protein kinase-interacting proteins Phyre2 PDB 6iq1 chain A Region: 14 - 155 Aligned: 134 Modelled: 142 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:adenosine 5'-monophosphoramidase; PDBTitle: crystal structure of histidine triad nucleotide-binding protein from2 candida albicans Phyre2 PDB 3l7x chain A Region: 13 - 155 Aligned: 135 Modelled: 143 Confidence: 100.0% Identity: 16% PDB header:cell cycle Chain: A: PDB Molecule:putative hit-like protein involved in cell-cycle PDBTitle: the crystal structure of smu.412c from streptococcus mutans ua159 Phyre2 PDB 3ksv chain A Region: 12 - 155 Aligned: 134 Modelled: 136 Confidence: 100.0% Identity: 12% PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: hypothetical protein from leishmania major Phyre2 PDB 3p0t chain B Region: 15 - 155 Aligned: 128 Modelled: 141 Confidence: 100.0% Identity: 10% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an hit-like protein from mycobacterium2 paratuberculosis Phyre2 PDB 3ano chain A Region: 3 - 154 Aligned: 139 Modelled: 152 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:ap-4-a phosphorylase; PDBTitle: crystal structure of a novel diadenosine 5',5'''-p1,p4-tetraphosphate2 phosphorylase from mycobacterium tuberculosis h37rv Phyre2 PDB 2eo4 chain A Region: 15 - 155 Aligned: 132 Modelled: 136 Confidence: 99.9% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:150aa long hypothetical histidine triad nucleotide-binding PDBTitle: crystal structure of hypothetical histidine triad nucleotide-binding2 protein st2152 from sulfolobus tokodaii strain7 Phyre2 PDB 4egu chain A Region: 11 - 136 Aligned: 117 Modelled: 126 Confidence: 99.9% Identity: 18% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:histidine triad (hit) protein; PDBTitle: 0.95a resolution structure of a histidine triad protein from2 clostridium difficile Phyre2 PDB 3n1t chain E Region: 14 - 125 Aligned: 110 Modelled: 112 Confidence: 99.9% Identity: 19% PDB header:hydrolase Chain: E: PDB Molecule:hit-like protein hint; PDBTitle: crystal structure of the h101a mutant echint gmp complex Phyre2 PDB 6d6j chain B Region: 14 - 118 Aligned: 103 Modelled: 105 Confidence: 99.9% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:hit family hydrolase; PDBTitle: crystal structure of hit family hydrolase from legionella pneumophila2 philadelphia 1 Phyre2 PDB 1xqu chain A Region: 13 - 125 Aligned: 111 Modelled: 113 Confidence: 99.9% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:hit family hydrolase; PDBTitle: hit family hydrolase from clostridium thermocellum cth-393 Phyre2 PDB 1xqu chain A Region: 13 - 125 Aligned: 111 Modelled: 113 Confidence: 99.9% Identity: 19% Fold: HIT-like Superfamily: HIT-like Family: HIT (HINT, histidine triad) family of protein kinase-interacting proteins Phyre2 1 d1guqa2 2 c5in3A_ 3 c1gupC_ 4 d1z84a2 5 c1zwjA_ 6 c3lb5B_ 7 c3imiB_ 8 c3o0mB_ 9 d1y23a_ 10 c6iq1A_ 11 c3l7xA_ 12 c3ksvA_ 13 c3p0tB_ 14 c3anoA_ 15 c2eo4A_ 16 c4eguA_ 17 c3n1tE_ 18 c6d6jB_ 19 c1xquA_ 20 d1xqua_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99