1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	L	S	I	K	H	P	E	A	D	R	L	A	R	A	L	A	A	R	T	G	E	T	L	T	E	A	V	V	T	A	L	R	E	R	L	A	R	E	T	G	R	A	R	V	V	P	L	R	D	E	L	A	A	I	R	H	R	C
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																																			?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.
Sequence		A	A	L	P	V	V	D	N	R	S	A	E	A	I	L	G	Y	D	E	R	G	L	P	A
Secondary structure
SS confidence
Disorder			?			?	?	?									?			?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 30%) Alpha helix ( 65%) Beta strand ( 0%)

Rank Aligned region

PDB 4xgq chain D Region: 48 - 76 Aligned: 29 Modelled: 29 Confidence: 94.3% Identity: 100% PDB header:toxin/antitoxin Chain: D: PDB Molecule:antitoxin vapb30; PDBTitle: crystal structure of addiction module from mycobacterial species Phyre2 PDB 4xgq chain B Region: 48 - 76 Aligned: 29 Modelled: 29 Confidence: 94.1% Identity: 100% PDB header:toxin/antitoxin Chain: B: PDB Molecule:antitoxin vapb30; PDBTitle: crystal structure of addiction module from mycobacterial species Phyre2 PDB 6a7v chain U Region: 11 - 44 Aligned: 34 Modelled: 34 Confidence: 84.6% Identity: 35% PDB header:toxin/antitoxin Chain: U: PDB Molecule:antitoxin vapb11; PDBTitle: crystal structure of mycobacterium tuberculosis vapbc11 toxin-2 antitoxin complex Phyre2 PDB 4xgr chain H Region: 51 - 74 Aligned: 24 Modelled: 24 Confidence: 79.4% Identity: 100% PDB header:toxin/antitoxin Chain: H: PDB Molecule:antitoxin vapb30; PDBTitle: crystal structure of addiction module from mycobacterial species Phyre2 PDB 6iya chain D Region: 2 - 45 Aligned: 44 Modelled: 44 Confidence: 67.3% Identity: 23% PDB header:antitoxin Chain: D: PDB Molecule:transcriptional regulator copg family; PDBTitle: structure of the dna binding domain of antitoxin copaso Phyre2 PDB 4xgr chain F Region: 51 - 73 Aligned: 23 Modelled: 23 Confidence: 67.0% Identity: 100% PDB header:toxin/antitoxin Chain: F: PDB Molecule:antitoxin vapb30; PDBTitle: crystal structure of addiction module from mycobacterial species Phyre2 PDB 2k5j chain B Region: 7 - 39 Aligned: 33 Modelled: 33 Confidence: 63.3% Identity: 12% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein yiif; PDBTitle: solution structure of protein yiif from shigella flexneri2 serotype 5b (strain 8401) . northeast structural genomics3 consortium target sft1 Phyre2 PDB 6gts chain C Region: 7 - 67 Aligned: 61 Modelled: 61 Confidence: 63.2% Identity: 15% PDB header:transcription Chain: C: PDB Molecule:duf1778 domain-containing protein; PDBTitle: structure of the atat-atar complex bound dna Phyre2 PDB 6ajn chain F Region: 7 - 52 Aligned: 46 Modelled: 46 Confidence: 56.4% Identity: 17% PDB header:toxin Chain: F: PDB Molecule:duf1778 domain-containing protein; PDBTitle: crystal structure of atatr bound with accoa Phyre2 PDB 2kel chain B Region: 25 - 39 Aligned: 15 Modelled: 15 Confidence: 51.9% Identity: 40% PDB header:transcription repressor Chain: B: PDB Molecule:uncharacterized protein 56b; PDBTitle: structure of the transcription regulator svtr from the2 hyperthermophilic archaeal virus sirv1 Phyre2 PDB 1y9b chain A domain 1 Region: 7 - 52 Aligned: 46 Modelled: 46 Confidence: 42.3% Identity: 20% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: VCA0319-like Phyre2 PDB 4q2u chain M Region: 7 - 82 Aligned: 74 Modelled: 76 Confidence: 42.2% Identity: 18% PDB header:toxin/toxin repressor Chain: M: PDB Molecule:antitoxin dinj; PDBTitle: crystal structure of the e. coli dinj-yafq toxin-antitoxin complex Phyre2 PDB 2q2k chain B Region: 3 - 38 Aligned: 36 Modelled: 36 Confidence: 26.0% Identity: 25% PDB header:dna binding protein/dna Chain: B: PDB Molecule:hypothetical protein; PDBTitle: structure of nucleic-acid binding protein Phyre2 PDB 2q2k chain A Region: 3 - 39 Aligned: 37 Modelled: 37 Confidence: 24.9% Identity: 24% PDB header:dna binding protein/dna Chain: A: PDB Molecule:hypothetical protein; PDBTitle: structure of nucleic-acid binding protein Phyre2 PDB 2rbf chain B Region: 7 - 44 Aligned: 38 Modelled: 38 Confidence: 22.6% Identity: 13% PDB header:oxidoreductase/dna Chain: B: PDB Molecule:bifunctional protein puta; PDBTitle: structure of the ribbon-helix-helix domain of escherichia coli puta2 (puta52) complexed with operator dna (o2) Phyre2 PDB 2hza chain A domain 1 Region: 1 - 44 Aligned: 44 Modelled: 44 Confidence: 18.2% Identity: 20% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: CopG-like Phyre2 PDB 2bsq chain E domain 1 Region: 7 - 61 Aligned: 51 Modelled: 55 Confidence: 16.0% Identity: 16% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: Trafficking protein A-like Phyre2 PDB 2xc7 chain A Region: 7 - 34 Aligned: 28 Modelled: 28 Confidence: 15.9% Identity: 14% PDB header:rna binding protein Chain: A: PDB Molecule:phosphorylated adapter rna export protein; PDBTitle: solution structure of phax-rbd in complex with ssrna Phyre2 PDB 1myl chain A Region: 9 - 42 Aligned: 34 Modelled: 34 Confidence: 15.6% Identity: 21% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: Arc/Mnt-like phage repressors Phyre2 PDB 2k9i chain B Region: 9 - 39 Aligned: 31 Modelled: 31 Confidence: 15.5% Identity: 23% PDB header:dna binding protein Chain: B: PDB Molecule:uncharacterized protein orf56; PDBTitle: nmr structure of plasmid copy control protein orf56 from sulfolobus2 islandicus Phyre2 1 c4xgqD_ 2 c4xgqB_ 3 c6a7vU_ 4 c4xgrH_ 5 c6iyaD_ 6 c4xgrF_ 7 c2k5jB_ 8 c6gtsC_ 9 c6ajnF_ 10 c2kelB_ 11 d1y9ba1 12 c4q2uM_ 13 c2q2kB_ 14 c2q2kA_ 15 c2rbfB_ 16 d2hzaa1 17 d2bsqe1 18 c2xc7A_ 19 d1myla_ 20 c2k9iB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97