1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	E	V	A	S	R	E	L	R	N	D	T	A	G	V	L	R	R	V	R	A	G	E	D	V	T	I	T	V	S	G	R	P	V	A	V	L	T	P	V	R	P	R	R	R	R	W	L	S	K	T	E	F	L	S	R	L	R	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?																																						?	?	?	?	?			?								?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.
Sequence		A	Q	A	D	P	G	L	R	N	D	L	A	V	L	A	G	D	T	T	E	D	L	G	P	I	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?													?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 33%) Alpha helix ( 51%) Beta strand ( 16%)

Rank Aligned region

PDB 2odk chain D Region: 1 - 46 Aligned: 46 Modelled: 45 Confidence: 99.4% Identity: 17% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:hypothetical protein; PDBTitle: putative prevent-host-death protein from nitrosomonas europaea Phyre2 PDB 2odk chain A domain 1 Region: 1 - 46 Aligned: 46 Modelled: 45 Confidence: 99.4% Identity: 17% Fold: YefM-like Superfamily: YefM-like Family: YefM-like Phyre2 PDB 3hry chain A Region: 1 - 46 Aligned: 46 Modelled: 46 Confidence: 99.2% Identity: 35% PDB header:antitoxin Chain: A: PDB Molecule:prevent host death protein; PDBTitle: crystal structure of phd in a trigonal space group and partially2 disordered Phyre2 PDB 3hs2 chain H Region: 1 - 46 Aligned: 46 Modelled: 46 Confidence: 99.2% Identity: 35% PDB header:antitoxin Chain: H: PDB Molecule:prevent host death protein; PDBTitle: crystal structure of phd truncated to residue 57 in an orthorhombic2 space group Phyre2 PDB 2a6q chain B domain 1 Region: 1 - 46 Aligned: 46 Modelled: 46 Confidence: 98.8% Identity: 15% Fold: YefM-like Superfamily: YefM-like Family: YefM-like Phyre2 PDB 3g5o chain A Region: 1 - 44 Aligned: 44 Modelled: 44 Confidence: 98.7% Identity: 23% PDB header:toxin/antitoxin Chain: A: PDB Molecule:uncharacterized protein rv2865; PDBTitle: the crystal structure of the toxin-antitoxin complex relbe2 (rv2865-2 2866) from mycobacterium tuberculosis Phyre2 PDB 2a6q chain A domain 1 Region: 1 - 44 Aligned: 44 Modelled: 44 Confidence: 98.6% Identity: 16% Fold: YefM-like Superfamily: YefM-like Family: YefM-like Phyre2 PDB 3oei chain B Region: 3 - 44 Aligned: 41 Modelled: 42 Confidence: 97.9% Identity: 22% PDB header:toxin, protein binding Chain: B: PDB Molecule:relj (antitoxin rv3357); PDBTitle: crystal structure of mycobacterium tuberculosis reljk (rv3357-rv3358-2 relbe3) Phyre2 PDB 3d55 chain A Region: 3 - 44 Aligned: 41 Modelled: 42 Confidence: 97.9% Identity: 22% PDB header:toxin inhibitor Chain: A: PDB Molecule:uncharacterized protein rv3357/mt3465; PDBTitle: crystal structure of m. tuberculosis yefm antitoxin Phyre2 PDB 3dbo chain A Region: 46 - 79 Aligned: 34 Modelled: 34 Confidence: 94.8% Identity: 100% PDB header:toxin/antitoxin Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a member of the vapbc family of toxin-antitoxin2 systems, vapbc-5, from mycobacterium tuberculosis Phyre2 PDB 3k6q chain B Region: 1 - 38 Aligned: 38 Modelled: 37 Confidence: 94.3% Identity: 11% PDB header:ligand binding protein Chain: B: PDB Molecule:putative ligand binding protein; PDBTitle: crystal structure of an antitoxin part of a putative toxin/antitoxin2 system (swol_0700) from syntrophomonas wolfei subsp. wolfei at 1.80 a3 resolution Phyre2 PDB 1sko chain A Region: 5 - 40 Aligned: 36 Modelled: 36 Confidence: 71.5% Identity: 17% PDB header:signaling protein Chain: A: PDB Molecule:mitogen-activated protein kinase kinase 1 PDBTitle: mp1-p14 complex Phyre2 PDB 3cpt chain A domain 1 Region: 8 - 40 Aligned: 33 Modelled: 33 Confidence: 62.2% Identity: 18% Fold: Profilin-like Superfamily: Roadblock/LC7 domain Family: Roadblock/LC7 domain Phyre2 PDB 2ns0 chain A domain 1 Region: 17 - 35 Aligned: 18 Modelled: 19 Confidence: 29.2% Identity: 33% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: RHA1 ro06458-like Phyre2 PDB 6c5r chain F Region: 11 - 34 Aligned: 24 Modelled: 24 Confidence: 16.0% Identity: 17% PDB header:cytosolic protein Chain: F: PDB Molecule:calcium uniporter; PDBTitle: crystal structure of the soluble domain of the mitochondrial calcium2 uniporter Phyre2 PDB 1x6v chain A domain 1 Region: 14 - 39 Aligned: 26 Modelled: 26 Confidence: 14.8% Identity: 23% Fold: PUA domain-like Superfamily: PUA domain-like Family: ATP sulfurylase N-terminal domain Phyre2 PDB 1k6m chain A domain 2 Region: 5 - 32 Aligned: 28 Modelled: 28 Confidence: 14.5% Identity: 14% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain Phyre2 PDB 1bif chain A domain 2 Region: 5 - 32 Aligned: 28 Modelled: 28 Confidence: 14.5% Identity: 14% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain Phyre2 PDB 4ewv chain B Region: 11 - 44 Aligned: 28 Modelled: 34 Confidence: 11.0% Identity: 29% PDB header:ligase Chain: B: PDB Molecule:4-substituted benzoates-glutamate ligase gh3.12; PDBTitle: crystal structure of gh3.12 in complex with ampcpp Phyre2 PDB 1tip chain A Region: 5 - 32 Aligned: 28 Modelled: 28 Confidence: 10.2% Identity: 14% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain Phyre2 1 c2odkD_ 2 d2odka1 3 c3hryA_ 4 c3hs2H_ 5 d2a6qb1 6 c3g5oA_ 7 d2a6qa1 8 c3oeiB_ 9 c3d55A_ 10 c3dboA_ 11 c3k6qB_ 12 c1skoA_ 13 d3cpta1 14 d2ns0a1 15 c6c5rF_ 16 d1x6va1 17 d1k6ma2 18 d1bifa2 19 c4ewvB_ 20 d1tipa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40