1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	R	G	E	L	W	F	A	A	T	P	G	G	D	R	P	V	L	V	L	T	R	D	P	V	A	D	R	I	G	A	V	V	V	V	A	L	T	R	T	R	R	G	L	V	S	E	L	E	L	T	A	V	E	N	R	V	P	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?																					?																												?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.
Sequence		D	C	V	V	N	F	D	N	I	H	T	L	P	R	T	A	F	R	R	R	I	T	R	L	S	P	A	R	L	H	E	A	C	Q	T	L	R	A	S	T	G	C
Secondary structure
SS confidence
Disorder																																								?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 13%) Alpha helix ( 23%) Beta strand ( 37%)

Rank Aligned region

PDB 1ub4 chain A Region: 2 - 101 Aligned: 96 Modelled: 100 Confidence: 100.0% Identity: 21% Fold: SH3-like barrel Superfamily: Cell growth inhibitor/plasmid maintenance toxic component Family: Kid/PemK Phyre2 PDB 5xe3 chain B Region: 2 - 101 Aligned: 92 Modelled: 91 Confidence: 99.9% Identity: 25% PDB header:hydrolase/antitoxin Chain: B: PDB Molecule:endoribonuclease mazf4; PDBTitle: endoribonuclease in complex with its cognate antitoxin from2 mycobacterial species Phyre2 PDB 4mzp chain C Region: 1 - 101 Aligned: 101 Modelled: 101 Confidence: 99.9% Identity: 28% PDB header:hydrolase Chain: C: PDB Molecule:mazf mrna interferase; PDBTitle: mazf from s. aureus crystal form iii, c2221, 2.7 a Phyre2 PDB 5hk3 chain B Region: 1 - 101 Aligned: 98 Modelled: 101 Confidence: 99.9% Identity: 31% PDB header:hydrolase/dna Chain: B: PDB Molecule:endoribonuclease mazf6; PDBTitle: crystal structure of m. tuberculosis mazf-mt3 t52d-f62d mutant in2 complex with dna Phyre2 PDB 5hjz chain A Region: 1 - 101 Aligned: 101 Modelled: 101 Confidence: 99.9% Identity: 26% PDB header:hydrolase/rna Chain: A: PDB Molecule:endoribonuclease mazf9; PDBTitle: structure of m. tuberculosis mazf-mt1 (rv2801c) in complex with rna Phyre2 PDB 5wyg chain C Region: 2 - 101 Aligned: 98 Modelled: 99 Confidence: 99.9% Identity: 27% PDB header:hydrolase Chain: C: PDB Molecule:probable endoribonuclease mazf7; PDBTitle: the crystal structure of the apo form of mtb mazf Phyre2 PDB 1ne8 chain A Region: 1 - 101 Aligned: 101 Modelled: 101 Confidence: 99.9% Identity: 28% Fold: SH3-like barrel Superfamily: Cell growth inhibitor/plasmid maintenance toxic component Family: Kid/PemK Phyre2 PDB 1m1f chain A Region: 1 - 100 Aligned: 98 Modelled: 100 Confidence: 99.9% Identity: 27% Fold: SH3-like barrel Superfamily: Cell growth inhibitor/plasmid maintenance toxic component Family: Kid/PemK Phyre2 PDB 5cca chain A Region: 14 - 101 Aligned: 87 Modelled: 88 Confidence: 99.9% Identity: 30% PDB header:hydrolase Chain: A: PDB Molecule:endoribonuclease mazf3; PDBTitle: crystal structure of mtb toxin Phyre2 PDB 3vub chain A Region: 5 - 100 Aligned: 94 Modelled: 96 Confidence: 96.5% Identity: 14% Fold: SH3-like barrel Superfamily: Cell growth inhibitor/plasmid maintenance toxic component Family: CcdB Phyre2 PDB 3jrz chain A Region: 13 - 100 Aligned: 82 Modelled: 88 Confidence: 95.8% Identity: 12% PDB header:toxin Chain: A: PDB Molecule:ccdb; PDBTitle: ccdbvfi-formii-ph5.6 Phyre2 PDB 5ikj chain A Region: 2 - 27 Aligned: 26 Modelled: 26 Confidence: 64.8% Identity: 19% PDB header:transcription Chain: A: PDB Molecule:cryptic loci regulator 2; PDBTitle: structure of clr2 bound to the clr1 c-terminus Phyre2 PDB 6bwq chain B Region: 5 - 22 Aligned: 18 Modelled: 18 Confidence: 21.1% Identity: 33% PDB header:metal binding protein Chain: B: PDB Molecule:pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel PDBTitle: larc2, the c-terminal domain of a cyclometallase involved in the2 synthesis of the npn cofactor of lactate racemase, in complex with3 mnctp Phyre2 PDB 3c19 chain A Region: 5 - 22 Aligned: 18 Modelled: 18 Confidence: 20.0% Identity: 22% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein mk0293; PDBTitle: crystal structure of protein mk0293 from methanopyrus kandleri av19 Phyre2 PDB 1rz4 chain A domain 1 Region: 70 - 96 Aligned: 27 Modelled: 27 Confidence: 17.9% Identity: 15% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Eukaryotic translation initiation factor 3 subunit 12, eIF3k, C-terminal domain Phyre2 PDB 3vdo chain B Region: 81 - 102 Aligned: 22 Modelled: 22 Confidence: 13.8% Identity: 9% PDB header:dna binding protein/protein binding Chain: B: PDB Molecule:anti-sigma-k factor rska; PDBTitle: structure of extra-cytoplasmic function(ecf) sigma factor sigk in2 complex with its negative regulator rska from mycobacterium3 tuberculosis Phyre2 PDB 1okj chain A domain 2 Region: 2 - 9 Aligned: 8 Modelled: 8 Confidence: 12.5% Identity: 50% Fold: Ribonuclease H-like motif Superfamily: Actin-like ATPase domain Family: YeaZ-like Phyre2 PDB 4p7x chain A Region: 1 - 101 Aligned: 93 Modelled: 101 Confidence: 12.4% Identity: 14% PDB header:oxidoreductase Chain: A: PDB Molecule:l-proline cis-4-hydroxylase; PDBTitle: l-pipecolic acid-bound l-proline cis-4-hydroxylase Phyre2 PDB 3llr chain A Region: 4 - 99 Aligned: 81 Modelled: 83 Confidence: 10.8% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:dna (cytosine-5)-methyltransferase 3a; PDBTitle: crystal structure of the pwwp domain of human dna (cytosine-5-)-2 methyltransferase 3 alpha Phyre2 PDB 1cff chain B Region: 1 - 8 Aligned: 8 Modelled: 8 Confidence: 10.5% Identity: 38% PDB header:calmodulin Chain: B: PDB Molecule:calcium pump; PDBTitle: nmr solution structure of a complex of calmodulin with a binding2 peptide of the ca2+-pump Phyre2 1 d1ub4a_ 2 c5xe3B_ 3 c4mzpC_ 4 c5hk3B_ 5 c5hjzA_ 6 c5wygC_ 7 d1ne8a_ 8 d1m1fa_ 9 c5ccaA_ 10 d3vuba_ 11 c3jrzA_ 12 c5ikjA_ 13 c6bwqB_ 14 c3c19A_ 15 d1rz4a1 16 c3vdoB_ 17 d1okja2 18 c4p7xA_ 19 c3llrA_ 20 c1cffB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54