1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	N	S	S	Y	H	R	R	V	P	V	V	G	E	L	G	S	A	T	S	S	Q	L	P	S	T	S	P	S	I	V	I	P	L	G	S	T	E	Q	H	G	P	H	L	P	L	D	T	D	T	R	I	A	T	A	V	A	R	T	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	A	R	L	H	A	E	D	L	P	I	A	Q	E	E	W	L	M	A	P	A	I	A	Y	G	A	S	G	E	H	Q	R	F	A	G	T	I	S	I	G	T	E	A	L	T	M	L	L	V	E	Y	G	R	S	A	A	C	W	A	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	L	V	F	V	N	G	H	G	G	N	V	G	A	L	T	R	A	V	G	L	L	R	A	E	G	R	D	A	G	W	C	P	C	T	C	P	G	G	D	P	H	A	G	H	T	E	T	S	V	L	L	H	L	S	P	A	D	V	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	E	R	W	R	A	G	N	R	A	P	L	P	V	L	L	P	S	M	R	R	G	G	V	A	A	V	S	E	T	G	V	L	G	D	P	T	T	A	T	A	A	E	G	R	R	I	F	A	A	M	V	D	D	C	V	R	R	V	A
Secondary structure
SS confidence
Disorder						?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.
Sequence		R	W	M	P	Q	P	D	G	M	L	T
Secondary structure
SS confidence
Disorder						?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 8%) Alpha helix ( 42%) Beta strand ( 10%)

Rank Aligned region

PDB 1v7z chain A Region: 8 - 247 Aligned: 226 Modelled: 240 Confidence: 100.0% Identity: 30% Fold: Creatininase Superfamily: Creatininase Family: Creatininase Phyre2 PDB 3no4 chain A Region: 8 - 245 Aligned: 225 Modelled: 238 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:creatinine amidohydrolase; PDBTitle: crystal structure of a creatinine amidohydrolase (npun_f1913) from2 nostoc punctiforme pcc 73102 at 2.00 a resolution Phyre2 PDB 3lub chain E Region: 14 - 246 Aligned: 227 Modelled: 233 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: E: PDB Molecule:putative creatinine amidohydrolase; PDBTitle: crystal structure of putative creatinine amidohydrolase (yp_211512.1)2 from bacteroides fragilis nctc 9343 at 2.11 a resolution Phyre2 PDB 2zqe chain A Region: 101 - 163 Aligned: 61 Modelled: 63 Confidence: 75.3% Identity: 23% PDB header:dna binding protein Chain: A: PDB Molecule:muts2 protein; PDBTitle: crystal structure of the smr domain of thermus thermophilus muts2 Phyre2 PDB 2lnd chain A Region: 44 - 146 Aligned: 71 Modelled: 73 Confidence: 65.8% Identity: 27% PDB header:de novo protein Chain: A: PDB Molecule:de novo designed protein, pfk fold; PDBTitle: solution nmr structure of de novo designed protein, pfk fold,2 northeast structural genomics consortium target or134 Phyre2 PDB 1un9 chain B Region: 82 - 248 Aligned: 157 Modelled: 167 Confidence: 57.8% Identity: 15% PDB header:kinase Chain: B: PDB Molecule:dihydroxyacetone kinase; PDBTitle: crystal structure of the dihydroxyacetone kinase from c.2 freundii in complex with amp-pnp and mg2+ Phyre2 PDB 2wyl chain F Region: 28 - 128 Aligned: 77 Modelled: 92 Confidence: 57.3% Identity: 13% PDB header:hydrolase Chain: F: PDB Molecule:l-ascorbate-6-phosphate lactonase ulag; PDBTitle: apo structure of a metallo-b-lactamase Phyre2 PDB 4och chain A Region: 99 - 164 Aligned: 64 Modelled: 66 Confidence: 56.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:endonuclease muts2; PDBTitle: apo structure of smr domain of muts2 from deinococcus radiodurans Phyre2 PDB 3qd7 chain X Region: 99 - 161 Aligned: 63 Modelled: 63 Confidence: 54.3% Identity: 16% PDB header:hydrolase Chain: X: PDB Molecule:uncharacterized protein ydal; PDBTitle: crystal structure of ydal, a stand-alone small muts-related protein2 from escherichia coli Phyre2 PDB 5t3o chain B Region: 49 - 160 Aligned: 98 Modelled: 112 Confidence: 47.1% Identity: 18% PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of the phosphorybosylpyrophosphate synthetase ii2 from thermus thermophilus Phyre2 PDB 3dah chain B Region: 49 - 128 Aligned: 66 Modelled: 80 Confidence: 45.0% Identity: 20% PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: 2.3 a crystal structure of ribose-phosphate pyrophosphokinase from2 burkholderia pseudomallei Phyre2 PDB 2qwx chain A domain 1 Region: 119 - 154 Aligned: 36 Modelled: 36 Confidence: 44.6% Identity: 19% Fold: Flavodoxin-like Superfamily: Flavoproteins Family: Quinone reductase Phyre2 PDB 3lot chain C Region: 38 - 111 Aligned: 52 Modelled: 63 Confidence: 38.9% Identity: 27% PDB header:structure genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of protein of unknown function (np_070038.1) from2 archaeoglobus fulgidus at 1.89 a resolution Phyre2 PDB 3eol chain B Region: 49 - 146 Aligned: 79 Modelled: 85 Confidence: 37.2% Identity: 13% PDB header:lyase Chain: B: PDB Molecule:isocitrate lyase; PDBTitle: 2.0a crystal structure of isocitrate lyase from brucella melitensis2 (p43212) Phyre2 PDB 4awa chain A Region: 92 - 130 Aligned: 39 Modelled: 39 Confidence: 36.7% Identity: 13% PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:legumain; PDBTitle: crystal structure of active legumain in complex with yvad-cmk2 at ph 5.0 Phyre2 PDB 3e02 chain A Region: 38 - 111 Aligned: 52 Modelled: 72 Confidence: 35.7% Identity: 25% PDB header:metal binding protein Chain: A: PDB Molecule:uncharacterized protein duf849; PDBTitle: crystal structure of a duf849 family protein (bxe_c0271) from2 burkholderia xenovorans lb400 at 1.90 a resolution Phyre2 PDB 4twb chain B Region: 49 - 153 Aligned: 91 Modelled: 105 Confidence: 34.1% Identity: 20% PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: sulfolobus solfataricus ribose-phosphate pyrophosphokinase Phyre2 PDB 1dku chain A domain 1 Region: 49 - 128 Aligned: 66 Modelled: 80 Confidence: 33.7% Identity: 21% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosylpyrophosphate synthetase-like Phyre2 PDB 3efh chain B Region: 49 - 128 Aligned: 66 Modelled: 80 Confidence: 31.1% Identity: 14% PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase 1; PDBTitle: crystal structure of human phosphoribosyl pyrophosphate2 synthetase 1 Phyre2 PDB 4s2u chain A Region: 49 - 135 Aligned: 73 Modelled: 85 Confidence: 29.6% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of the phosphorybosylpyrophosphate synthetase from2 e. coli Phyre2 1 d1v7za_ 2 c3no4A_ 3 c3lubE_ 4 c2zqeA_ 5 c2lndA_ 6 c1un9B_ 7 c2wylF_ 8 c4ochA_ 9 c3qd7X_ 10 c5t3oB_ 11 c3dahB_ 12 d2qwxa1 13 c3lotC_ 14 c3eolB_ 15 c4awaA_ 16 c3e02A_ 17 c4twbB_ 18 d1dkua1 19 c3efhB_ 20 c4s2uA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99