1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	A	T	R	L	P	D	G	F	A	V	Q	V	D	R	R	V	R	V	L	G	D	G	S	A	L	L	G	G	S	P	T	R	L	L	R	L	A	P	A	A	R	G	L	L	C	D	G	R	L	K	V	R	D	E	V	S	A	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?											?		?	?	?	?															?									?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	A	R	I	L	L	D	A	T	V	A	H	P	R	P	P	S	G	P	S	H	R	D	V	T	V	V	I	P	V	R	N	N	A	S	G	L	R	R	L	V	T	S	L	R	G	L	R	V	I	V	V	D	D	G	S	A	C	P	V
Secondary structure
SS confidence
Disorder									?					?			?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	S	D	D	F	V	G	A	H	C	D	I	E	V	L	H	H	P	H	S	K	G	P	A	A	A	R	N	T	G	L	A	A	C	T	T	D	F	V	A	F	L	D	S	D	V	T	P	R	R	G	W	L	E	S	L	L	G	H	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		C	D	P	T	V	A	L	V	A	P	R	I	V	S	L	V	E	G	E	N	P	V	A	R	Y	E	A	L	H	S	S	L	D	L	G	Q	R	E	A	P	V	L	P	H	S	T	V	S	Y	V	P	S	A	A	I	V	C	R	S	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	I	R	D	V	G	G	F	D	E	T	M	H	S	G	E	D	V	D	L	C	W	R	L	I	E	A	G	A	R	L	R	Y	E	P	I	A	L	V	A	H	D	H	R	T	Q	L	R	D	W	I	A	R	K	A	F	Y	G	G	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		A	A	P	L	A	V	R	H	P	D	K	T	A	P	L	V	I	S	G	G	A	L	M	A	W	I	L	M	S	I	G	T	G	L	G	R	L	A	S	L	V	I	A	V	L	T	G	R	R	I	A	R	A	M	R	C	A	E	T	S
Secondary structure
SS confidence
Disorder													?																				?	?	?																				?	?	?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		F	L	D	V	L	A	V	A	T	R	G	L	W	A	A	A	L	Q	L	A	S	A	I	C	R	H	Y	W	P	L	A	L	L	A	A	I	L	S	R	R	C	R	R	V	V	L	I	A	A	V	V	D	G	V	V	D	W	L	R	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470
Sequence		R	E	G	A	D	D	D	A	E	P	I	G	P	L	T	Y	L	V	L	K	R	V	D	D	L	A	Y	G	A	G	L	W	Y	G	V	V	R	E	R	N	I	G	A	L	K	P	Q	I	R	T
Secondary structure
SS confidence
Disorder			?		?	?	?	?	?	?	?	?																																	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 12%) Alpha helix ( 53%) Beta strand ( 12%) TM helix ( 21%) (View membrane topology prediction)

Rank Aligned region

PDB 4hg6 chain A Region: 73 - 453 Aligned: 377 Modelled: 381 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:cellulose synthase subunit a; PDBTitle: structure of a cellulose synthase - cellulose translocation2 intermediate Phyre2 PDB 5nqa chain A Region: 77 - 293 Aligned: 217 Modelled: 217 Confidence: 100.0% Identity: 23% PDB header:transferase Chain: A: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 4; PDBTitle: crystal structure of galnac-t4 in complex with the monoglycopeptide 3 Phyre2 PDB 6e4r chain B Region: 78 - 295 Aligned: 218 Modelled: 218 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: B: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 9; PDBTitle: crystal structure of the drosophila melanogaster polypeptide n-2 acetylgalactosaminyl transferase pgant9b Phyre2 PDB 1xhb chain A Region: 78 - 293 Aligned: 216 Modelled: 216 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 1; PDBTitle: the crystal structure of udp-galnac: polypeptide alpha-n-2 acetylgalactosaminyltransferase-t1 Phyre2 PDB 2d7i chain A Region: 78 - 286 Aligned: 209 Modelled: 209 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 10; PDBTitle: crystal structure of pp-galnac-t10 with udp, galnac and mn2+ Phyre2 PDB 2ffu chain A Region: 78 - 286 Aligned: 208 Modelled: 209 Confidence: 100.0% Identity: 24% PDB header:transferase Chain: A: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 2; PDBTitle: crystal structure of human ppgalnact-2 complexed with udp and ea2 Phyre2 PDB 6iwq chain E Region: 78 - 286 Aligned: 209 Modelled: 209 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: E: PDB Molecule:n-acetylgalactosaminyltransferase 7; PDBTitle: crystal structure of galnac-t7 with mn2+ Phyre2 PDB 1xhb chain A domain 2 Region: 78 - 293 Aligned: 216 Modelled: 216 Confidence: 100.0% Identity: 21% Fold: Nucleotide-diphospho-sugar transferases Superfamily: Nucleotide-diphospho-sugar transferases Family: Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain Phyre2 PDB 4fix chain A Region: 74 - 352 Aligned: 278 Modelled: 279 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:udp-galactofuranosyl transferase glft2; PDBTitle: crystal structure of glft2 Phyre2 PDB 2z86 chain D Region: 77 - 294 Aligned: 218 Modelled: 218 Confidence: 100.0% Identity: 24% PDB header:transferase Chain: D: PDB Molecule:chondroitin synthase; PDBTitle: crystal structure of chondroitin polymerase from escherichia coli2 strain k4 (k4cp) complexed with udp-glcua and udp Phyre2 PDB 5mm1 chain A Region: 83 - 405 Aligned: 318 Modelled: 323 Confidence: 100.0% Identity: 14% PDB header:membrane protein Chain: A: PDB Molecule:dolichol monophosphate mannose synthase; PDBTitle: dolichyl phosphate mannose synthase in complex with gdp and dolichyl2 phosphate mannose Phyre2 PDB 5tz8 chain C Region: 83 - 294 Aligned: 204 Modelled: 212 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: C: PDB Molecule:glycosyl transferase; PDBTitle: crystal structure of s. aureus tars Phyre2 PDB 6h4m chain A Region: 82 - 286 Aligned: 199 Modelled: 205 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:probable ss-1,3-n-acetylglucosaminyltransferase; PDBTitle: tarp-udp-glcnac-3rbop Phyre2 PDB 3f1y chain C Region: 81 - 312 Aligned: 225 Modelled: 232 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: C: PDB Molecule:mannosyl-3-phosphoglycerate synthase; PDBTitle: mannosyl-3-phosphoglycerate synthase from rubrobacter xylanophilus Phyre2 PDB 3zf8 chain A Region: 72 - 286 Aligned: 215 Modelled: 215 Confidence: 100.0% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:mannan polymerase complexes subunit mnn9; PDBTitle: crystal structure of saccharomyces cerevisiae mnn9 in2 complex with gdp and mn. Phyre2 PDB 3ckv chain A Region: 79 - 303 Aligned: 213 Modelled: 225 Confidence: 100.0% Identity: 20% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of a mycobacterial protein Phyre2 PDB 5eke chain B Region: 78 - 351 Aligned: 250 Modelled: 259 Confidence: 100.0% Identity: 15% PDB header:transferase Chain: B: PDB Molecule:uncharacterized glycosyltransferase sll0501; PDBTitle: structure of the polyisoprenyl-phosphate glycosyltransferase gtrb2 (f215a mutant) Phyre2 PDB 5hea chain A Region: 81 - 297 Aligned: 215 Modelled: 217 Confidence: 99.9% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:putative glycosyltransferase (galt1); PDBTitle: cgt structure in hexamer Phyre2 PDB 3bcv chain A Region: 82 - 275 Aligned: 186 Modelled: 194 Confidence: 99.9% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:putative glycosyltransferase protein; PDBTitle: crystal structure of a putative glycosyltransferase from bacteroides2 fragilis Phyre2 PDB 1qg8 chain A Region: 82 - 294 Aligned: 201 Modelled: 212 Confidence: 99.9% Identity: 12% Fold: Nucleotide-diphospho-sugar transferases Superfamily: Nucleotide-diphospho-sugar transferases Family: Spore coat polysaccharide biosynthesis protein SpsA Phyre2 1 c4hg6A_ 2 c5nqaA_ 3 c6e4rB_ 4 c1xhbA_ 5 c2d7iA_ 6 c2ffuA_ 7 c6iwqE_ 8 d1xhba2 9 c4fixA_ 10 c2z86D_ 11 c5mm1A_ 12 c5tz8C_ 13 c6h4mA_ 14 c3f1yC_ 15 c3zf8A_ 16 c3ckvA_ 17 c5ekeB_ 18 c5heaA_ 19 c3bcvA_ 20 d1qg8a_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122