1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	L	T	E	L	V	D	L	P	G	G	S	F	R	M	G	S	T	R	F	Y	P	E	E	A	P	I	H	T	V	T	V	R	A	F	A	V	E	R	H	P	V	T	N	A	Q	F	A	E	F	V	S	A	T	G	Y	V	T	V	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?														?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	Q	P	L	D	P	G	L	Y	P	G	V	D	A	A	D	L	C	P	G	A	M	V	F	C	P	T	A	G	P	V	D	L	R	D	W	R	Q	W	W	D	W	V	P	G	A	C	W	R	H	P	F	G	R	D	S	D	I	A	D
Secondary structure
SS confidence
Disorder		?	?	?	?		?	?	?	?					?	?																																							?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	A	G	H	P	V	V	Q	V	A	Y	P	D	A	V	A	Y	A	R	W	A	G	R	R	L	P	T	E	A	E	W	E	Y	A	A	R	G	G	T	T	A	T	Y	A	W	G	D	Q	E	K	P	G	G	M	L	M	A	N	T	W
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	G	R	F	P	Y	R	N	D	G	A	L	G	W	V	G	T	S	P	V	G	R	F	P	A	N	G	F	G	L	L	D	M	I	G	N	V	W	E	W	T	T	T	E	F	Y	P	H	H	R	I	D	P	P	S	T	A	C	C	A
Secondary structure
SS confidence
Disorder													?																																					?	?		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.
Sequence		P	V	K	L	A	T	A	A	D	P	T	I	S	Q	T	L	K	G	G	S	H	L	C	A	P	E	Y	C	H	R	Y	R	P	A	A	R	S	P	Q	S	Q	D	T	A	T	T	H	I	G	F	R	C	V	A	D	P	V	S	G
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?																														?	?	?												?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 17%) Alpha helix ( 17%) Beta strand ( 14%)

Rank Aligned region

PDB 5nyy chain A Region: 3 - 296 Aligned: 271 Modelled: 275 Confidence: 100.0% Identity: 46% PDB header:transferase Chain: A: PDB Molecule:non-specific serine/threonine protein kinase; PDBTitle: formylglycine generating enzyme from t. curvata in complex with cd(ii) Phyre2 PDB 2q17 chain C Region: 1 - 295 Aligned: 278 Modelled: 295 Confidence: 100.0% Identity: 46% PDB header:unknown function Chain: C: PDB Molecule:formylglycine generating enzyme; PDBTitle: formylglycine generating enzyme from streptomyces coelicolor Phyre2 PDB 1z70 chain X domain 1 Region: 2 - 298 Aligned: 268 Modelled: 278 Confidence: 100.0% Identity: 43% Fold: C-type lectin-like Superfamily: C-type lectin-like Family: Sulfatase-modifying factor-like Phyre2 PDB 1y1f chain X Region: 3 - 298 Aligned: 264 Modelled: 273 Confidence: 100.0% Identity: 45% PDB header:oxidoreductase Chain: X: PDB Molecule:c-alpha-formyglycine-generating enzyme; PDBTitle: human formylglycine generating enzyme with cysteine sulfenic acid Phyre2 PDB 4x8b chain A Region: 3 - 295 Aligned: 252 Modelled: 268 Confidence: 100.0% Identity: 30% PDB header:oxidoreductase Chain: A: PDB Molecule:sulfoxide synthase egtb; PDBTitle: ergothioneine-biosynthetic sulfoxide synthase egtb, apo form Phyre2 PDB 1y4j chain A domain 1 Region: 3 - 295 Aligned: 259 Modelled: 272 Confidence: 100.0% Identity: 39% Fold: C-type lectin-like Superfamily: C-type lectin-like Family: Sulfatase-modifying factor-like Phyre2 PDB 5hha chain B Region: 4 - 295 Aligned: 234 Modelled: 243 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: B: PDB Molecule:pvdo; PDBTitle: structure of pvdo from pseudomonas aeruginosa Phyre2 PDB 6qkj chain A Region: 3 - 295 Aligned: 234 Modelled: 241 Confidence: 100.0% Identity: 24% PDB header:oxidoreductase Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: egtb from chloracidobacterium thermophilum, a type ii sulfoxide2 synthase in complex with n,n,n-trimethyl-histidine Phyre2 PDB 2y3c chain A Region: 4 - 296 Aligned: 254 Modelled: 267 Confidence: 100.0% Identity: 22% PDB header:unknown function Chain: A: PDB Molecule:treponema denticola variable protein 1; PDBTitle: treponema denticola variable protein 1 Phyre2 PDB 5aoh chain A Region: 4 - 295 Aligned: 222 Modelled: 227 Confidence: 100.0% Identity: 27% PDB header:unknown function Chain: A: PDB Molecule:carf; PDBTitle: crystal structure of carf Phyre2 PDB 1yu0 chain A domain 2 Region: 26 - 297 Aligned: 199 Modelled: 207 Confidence: 100.0% Identity: 20% Fold: C-type lectin-like Superfamily: C-type lectin-like Family: Mtd variable domain Phyre2 PDB 1yu3 chain A domain 2 Region: 26 - 297 Aligned: 199 Modelled: 207 Confidence: 100.0% Identity: 20% Fold: C-type lectin-like Superfamily: C-type lectin-like Family: Mtd variable domain Phyre2 PDB 2iou chain C Region: 114 - 295 Aligned: 156 Modelled: 164 Confidence: 100.0% Identity: 19% PDB header:viral protein/membrane protein Chain: C: PDB Molecule:major tropism determinant p1; PDBTitle: major tropism determinant p1 (mtd-p1) variant complexed with2 bordetella brochiseptica virulence factor pertactin extracellular3 domain (prn-e). Phyre2 PDB 5vf4 chain A Region: 5 - 294 Aligned: 215 Modelled: 225 Confidence: 100.0% Identity: 27% PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: thermus aquaticus variable protein (taqvp) from diversity-generating2 retroelements (dgr) Phyre2 PDB 1e5u chain I Region: 129 - 147 Aligned: 19 Modelled: 19 Confidence: 85.7% Identity: 42% PDB header:intimin Chain: I: PDB Molecule:intimin; PDBTitle: nmr representative structure of intimin-190 (int190) from2 enteropathogenic e. coli Phyre2 PDB 3k7b chain A Region: 129 - 148 Aligned: 20 Modelled: 18 Confidence: 67.3% Identity: 25% PDB header:viral protein Chain: A: PDB Molecule:protein a33; PDBTitle: the structure of the poxvirus a33 protein reveals a dimer of unique c-2 type lectin-like domains. Phyre2 PDB 1g1t chain A domain 1 Region: 129 - 147 Aligned: 19 Modelled: 19 Confidence: 57.1% Identity: 26% Fold: C-type lectin-like Superfamily: C-type lectin-like Family: C-type lectin domain Phyre2 PDB 1byf chain A Region: 129 - 147 Aligned: 19 Modelled: 19 Confidence: 56.9% Identity: 32% Fold: C-type lectin-like Superfamily: C-type lectin-like Family: C-type lectin domain Phyre2 PDB 2msb chain A Region: 129 - 147 Aligned: 19 Modelled: 19 Confidence: 56.7% Identity: 5% Fold: C-type lectin-like Superfamily: C-type lectin-like Family: C-type lectin domain Phyre2 PDB 1fm5 chain A Region: 129 - 147 Aligned: 19 Modelled: 19 Confidence: 55.1% Identity: 16% PDB header:immune system Chain: A: PDB Molecule:early activation antigen cd69; PDBTitle: crystal structure of human cd69 Phyre2 1 c5nyyA_ 2 c2q17C_ 3 d1z70x1 4 c1y1fX_ 5 c4x8bA_ 6 d1y4ja1 7 c5hhaB_ 8 c6qkjA_ 9 c2y3cA_ 10 c5aohA_ 11 d1yu0a2 12 d1yu3a2 13 c2iouC_ 14 c5vf4A_ 15 c1e5uI_ 16 c3k7bA_ 17 d1g1ta1 18 d1byfa_ 19 d2msba_ 20 c1fm5A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99