1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	T	L	K	L	H	D	L	R	P	A	R	G	S	K	I	A	R	T	R	V	G	R	G	D	G	S	K	G	K	T	A	G	R	G	T	K	G	T	R	A	R	K	Q	V	P	V	T	F	E	G	G	Q	M	P	I	H	M	R	L
Secondary structure
SS confidence
Disorder		?	?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	K	L	K	G	F	R	N	R	F	R	T	E	Y	E	I	V	N	V	G	D	I	N	R	L	F	P	Q	G	G	A	V	G	V	D	D	L	V	A	K	G	A	V	R	K	N	A	L	V	K	V	L	G	D	G	K	L	T	A	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.
Sequence		V	D	V	S	A	H	K	F	S	G	S	A	R	A	K	I	T	A	A	G	G	S	A	T	E	L
Secondary structure
SS confidence
Disorder																											?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 33%) Alpha helix ( 20%) Beta strand ( 21%)

Rank Aligned region

PDB 5o60 chain M Region: 3 - 146 Aligned: 144 Modelled: 144 Confidence: 100.0% Identity: 83% PDB header:ribosome Chain: M: PDB Molecule:50s ribosomal protein l15; PDBTitle: structure of the 50s large ribosomal subunit from mycobacterium2 smegmatis Phyre2 PDB 1vw4 chain J Region: 5 - 146 Aligned: 141 Modelled: 142 Confidence: 100.0% Identity: 37% PDB header:ribosome Chain: J: PDB Molecule:54s ribosomal protein l10, mitochondrial; PDBTitle: structure of the yeast mitochondrial large ribosomal subunit Phyre2 PDB 3j3v chain L Region: 3 - 146 Aligned: 142 Modelled: 144 Confidence: 100.0% Identity: 51% PDB header:ribosome Chain: L: PDB Molecule:50s ribosomal protein l15; PDBTitle: atomic model of the immature 50s subunit from bacillus subtilis (state2 i-a) Phyre2 PDB 3bbo chain N Region: 3 - 146 Aligned: 144 Modelled: 144 Confidence: 100.0% Identity: 38% PDB header:ribosome Chain: N: PDB Molecule:ribosomal protein l15; PDBTitle: homology model for the spinach chloroplast 50s subunit fitted to 9.4a2 cryo-em map of the 70s chlororibosome Phyre2 PDB 2zjr chain I domain 1 Region: 6 - 146 Aligned: 137 Modelled: 141 Confidence: 100.0% Identity: 42% Fold: Ribosomal proteins L15p and L18e Superfamily: Ribosomal proteins L15p and L18e Family: Ribosomal proteins L15p and L18e Phyre2 PDB 4ce4 chain P Region: 1 - 145 Aligned: 141 Modelled: 143 Confidence: 100.0% Identity: 33% PDB header:ribosome Chain: P: PDB Molecule:mrpl15; PDBTitle: 39s large subunit of the porcine mitochondrial ribosome Phyre2 PDB 2gyc chain J domain 1 Region: 6 - 144 Aligned: 136 Modelled: 139 Confidence: 100.0% Identity: 42% Fold: Ribosomal proteins L15p and L18e Superfamily: Ribosomal proteins L15p and L18e Family: Ribosomal proteins L15p and L18e Phyre2 PDB 4v19 chain P Region: 2 - 146 Aligned: 141 Modelled: 142 Confidence: 100.0% Identity: 33% PDB header:ribosome Chain: P: PDB Molecule:mitoribosomal protein ul15m, mrpl15; PDBTitle: structure of the large subunit of the mammalian mitoribosome, part 12 of 2 Phyre2 PDB 2j01 chain P domain 1 Region: 7 - 146 Aligned: 135 Modelled: 139 Confidence: 100.0% Identity: 47% Fold: Ribosomal proteins L15p and L18e Superfamily: Ribosomal proteins L15p and L18e Family: Ribosomal proteins L15p and L18e Phyre2 PDB 3j21 chain L Region: 14 - 146 Aligned: 132 Modelled: 133 Confidence: 100.0% Identity: 26% PDB header:ribosome Chain: L: PDB Molecule:50s ribosomal protein l15p; PDBTitle: promiscuous behavior of proteins in archaeal ribosomes revealed by2 cryo-em: implications for evolution of eukaryotic ribosomes (50s3 ribosomal proteins) Phyre2 PDB 4a1c chain K Region: 14 - 146 Aligned: 129 Modelled: 133 Confidence: 100.0% Identity: 28% PDB header:ribosome Chain: K: PDB Molecule:60s ribosomal protein l27a; PDBTitle: t.thermophila 60s ribosomal subunit in complex with2 initiation factor 6. this file contains 5s rrna,3 5.8s rrna and proteins of molecule 4. Phyre2 PDB 1vqo chain L domain 1 Region: 14 - 146 Aligned: 128 Modelled: 133 Confidence: 100.0% Identity: 29% Fold: Ribosomal proteins L15p and L18e Superfamily: Ribosomal proteins L15p and L18e Family: Ribosomal proteins L15p and L18e Phyre2 PDB 3zf7 chain B Region: 13 - 146 Aligned: 130 Modelled: 134 Confidence: 100.0% Identity: 25% PDB header:ribosome Chain: B: PDB Molecule: PDBTitle: high-resolution cryo-electron microscopy structure of the trypanosoma2 brucei ribosome Phyre2 PDB 3j39 chain A Region: 13 - 146 Aligned: 130 Modelled: 134 Confidence: 100.0% Identity: 28% PDB header:ribosome Chain: A: PDB Molecule:60s ribosomal protein l8; PDBTitle: structure of the d. melanogaster 60s ribosomal proteins Phyre2 PDB 2zkr chain L Region: 17 - 146 Aligned: 121 Modelled: 130 Confidence: 100.0% Identity: 28% PDB header:ribosomal protein/rna Chain: L: PDB Molecule:rna expansion segment es20; PDBTitle: structure of a mammalian ribosomal 60s subunit within an 80s complex2 obtained by docking homology models of the rna and proteins into an3 8.7 a cryo-em map Phyre2 PDB 1s1i chain V Region: 17 - 146 Aligned: 130 Modelled: 130 Confidence: 100.0% Identity: 23% PDB header:ribosome Chain: V: PDB Molecule:60s ribosomal protein l28; PDBTitle: structure of the ribosomal 80s-eef2-sordarin complex from yeast2 obtained by docking atomic models for rna and protein components into3 a 11.7 a cryo-em map. this file, 1s1i, contains 60s subunit. the 40s4 ribosomal subunit is in file 1s1h. Phyre2 PDB 3iz5 chain O Region: 14 - 146 Aligned: 128 Modelled: 133 Confidence: 100.0% Identity: 27% PDB header:ribosome Chain: O: PDB Molecule:60s ribosomal protein l27a (l15p); PDBTitle: localization of the large subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome Phyre2 PDB 3j21 chain P Region: 71 - 146 Aligned: 63 Modelled: 76 Confidence: 99.4% Identity: 51% PDB header:ribosome Chain: P: PDB Molecule:50s ribosomal protein l18e; PDBTitle: promiscuous behavior of proteins in archaeal ribosomes revealed by2 cryo-em: implications for evolution of eukaryotic ribosomes (50s3 ribosomal proteins) Phyre2 PDB 1vqo chain O domain 1 Region: 71 - 144 Aligned: 61 Modelled: 74 Confidence: 99.3% Identity: 43% Fold: Ribosomal proteins L15p and L18e Superfamily: Ribosomal proteins L15p and L18e Family: Ribosomal proteins L15p and L18e Phyre2 PDB 3j3b chain Q Region: 71 - 146 Aligned: 63 Modelled: 76 Confidence: 98.9% Identity: 27% PDB header:ribosome Chain: Q: PDB Molecule:60s ribosomal protein l18; PDBTitle: structure of the human 60s ribosomal proteins Phyre2 1 c5o60M_ 2 c1vw4J_ 3 c3j3vL_ 4 c3bboN_ 5 d2zjri1 6 c4ce4P_ 7 d2gycj1 8 c4v19P_ 9 d2j01p1 10 c3j21L_ 11 c4a1cK_ 12 d1vqol1 13 c3zf7b_ 14 c3j39a_ 15 c2zkrl_ 16 c1s1iV_ 17 c3iz5O_ 18 c3j21P_ 19 d1vqoo1 20 c3j3bQ_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58