1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	F	V	D	A	P	E	S	A	V	L	A	A	A	K	D	M	L	R	R	G	L	V	E	G	T	A	G	N	I	S	A	R	R	S	D	G	N	V	V	I	T	P	S	S	V	D	Y	A	E	M	L	L	H	D	L	V	L	V
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	A	G	G	A	V	L	H	A	K	D	G	R	S	P	S	T	E	L	N	L	H	L	A	C	Y	R	A	F	D	D	I	G	S	V	I	H	S	H	P	V	W	A	T	M	F	A	V	A	H	E	P	I	P	A	C	I	D	E	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	I	Y	C	G	G	D	V	R	C	T	E	Y	A	A	S	G	T	P	E	V	G	R	N	A	V	R	A	L	E	G	R	A	A	A	L	I	A	N	H	G	L	V	A	V	G	P	R	P	D	Q	V	L	R	V	T	A	L	V	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.
Sequence		R	T	A	Q	I	V	W	G	A	R	A	L	G	G	P	V	P	I	P	E	D	V	C	R	N	F	T	G	V	Y	G	Y	L	R	A	N	P	L
Secondary structure
SS confidence
Disorder														?	?	?	?	?	?														?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 7%) Alpha helix ( 42%) Beta strand ( 16%)

Rank Aligned region

PDB 1ojr chain A Region: 1 - 218 Aligned: 215 Modelled: 218 Confidence: 100.0% Identity: 21% Fold: AraD/HMP-PK domain-like Superfamily: AraD/HMP-PK domain-like Family: AraD-like aldolase/epimerase Phyre2 PDB 4c24 chain A Region: 5 - 210 Aligned: 203 Modelled: 206 Confidence: 100.0% Identity: 35% PDB header:lyase Chain: A: PDB Molecule:l-fuculose phosphate aldolase; PDBTitle: l-fuculose 1-phosphate aldolase Phyre2 PDB 1e4c chain P Region: 1 - 210 Aligned: 205 Modelled: 209 Confidence: 100.0% Identity: 29% Fold: AraD/HMP-PK domain-like Superfamily: AraD/HMP-PK domain-like Family: AraD-like aldolase/epimerase Phyre2 PDB 6btd chain A Region: 4 - 206 Aligned: 200 Modelled: 203 Confidence: 100.0% Identity: 35% PDB header:lyase Chain: A: PDB Molecule:fuculose phosphate aldolase; PDBTitle: crystal structure of deoxyribose-phosphate aldolase from bacillus2 thuringiensis involved in dispatching the ubiquitous radical sam3 enzyme byproduct 5-deoxyribose Phyre2 PDB 3ocr chain A Region: 6 - 217 Aligned: 212 Modelled: 212 Confidence: 100.0% Identity: 17% PDB header:lyase Chain: A: PDB Molecule:class ii aldolase/adducin domain protein; PDBTitle: crystal structure of aldolase ii superfamily protein from pseudomonas2 syringae Phyre2 PDB 4xxf chain A Region: 5 - 212 Aligned: 200 Modelled: 208 Confidence: 100.0% Identity: 22% PDB header:lyase Chain: A: PDB Molecule:fuculose-1-phosphate aldolase; PDBTitle: l-fuculose 1-phosphate aldolase from glaciozyma antarctica pi12 Phyre2 PDB 2z7b chain A Region: 1 - 212 Aligned: 207 Modelled: 209 Confidence: 100.0% Identity: 20% PDB header:lyase Chain: A: PDB Molecule:mlr6791 protein; PDBTitle: crystal structure of mesorhizobium loti 3-hydroxy-2-methylpyridine-4,2 5-dicarboxylate decarboxylase Phyre2 PDB 2opi chain B Region: 5 - 208 Aligned: 199 Modelled: 204 Confidence: 100.0% Identity: 21% PDB header:lyase Chain: B: PDB Molecule:l-fuculose-1-phosphate aldolase; PDBTitle: crystal structure of l-fuculose-1-phosphate aldolase from bacteroides2 thetaiotaomicron Phyre2 PDB 1k0w chain A Region: 3 - 210 Aligned: 206 Modelled: 208 Confidence: 100.0% Identity: 30% Fold: AraD/HMP-PK domain-like Superfamily: AraD/HMP-PK domain-like Family: AraD-like aldolase/epimerase Phyre2 PDB 2fk5 chain B Region: 5 - 197 Aligned: 186 Modelled: 193 Confidence: 100.0% Identity: 27% PDB header:lyase Chain: B: PDB Molecule:fuculose-1-phosphate aldolase; PDBTitle: crystal structure of l-fuculose-1-phosphate aldolase from thermus2 thermophilus hb8 Phyre2 PDB 1pvt chain A Region: 5 - 196 Aligned: 190 Modelled: 192 Confidence: 100.0% Identity: 27% Fold: AraD/HMP-PK domain-like Superfamily: AraD/HMP-PK domain-like Family: AraD-like aldolase/epimerase Phyre2 PDB 4m6r chain A Region: 1 - 199 Aligned: 196 Modelled: 199 Confidence: 100.0% Identity: 20% PDB header:lyase Chain: A: PDB Molecule:methylthioribulose-1-phosphate dehydratase; PDBTitle: structural and biochemical basis for the inhibition of cell death by2 apip, a methionine salvage enzyme Phyre2 PDB 2irp chain A Region: 4 - 192 Aligned: 186 Modelled: 189 Confidence: 100.0% Identity: 23% PDB header:lyase Chain: A: PDB Molecule:putative aldolase class 2 protein aq_1979; PDBTitle: crystal structure of the l-fuculose-1-phosphate aldolase (aq_1979)2 from aquifex aeolicus vf5 Phyre2 PDB 3m4r chain A Region: 8 - 188 Aligned: 171 Modelled: 181 Confidence: 100.0% Identity: 18% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: structure of the n-terminal class ii aldolase domain of a conserved2 protein from thermoplasma acidophilum Phyre2 PDB 4xae chain B Region: 125 - 162 Aligned: 38 Modelled: 38 Confidence: 59.2% Identity: 16% PDB header:oxidoreductase Chain: B: PDB Molecule:feruloyl coa ortho-hydroxylase 1; PDBTitle: structure of feruloyl-coa 6-hydroxylase (f6h) from arabidopsis2 thaliana Phyre2 PDB 1w9y chain A domain 1 Region: 126 - 162 Aligned: 37 Modelled: 37 Confidence: 27.7% Identity: 14% Fold: Double-stranded beta-helix Superfamily: Clavaminate synthase-like Family: Penicillin synthase-like Phyre2 PDB 1odm chain A Region: 127 - 162 Aligned: 36 Modelled: 36 Confidence: 27.6% Identity: 17% Fold: Double-stranded beta-helix Superfamily: Clavaminate synthase-like Family: Penicillin synthase-like Phyre2 PDB 5gj9 chain A Region: 127 - 162 Aligned: 36 Modelled: 36 Confidence: 26.8% Identity: 19% PDB header:oxidoreductase Chain: A: PDB Molecule:1-aminocyclopropane-1-carboxylate oxidase 2; PDBTitle: crystal structure of arabidopsis thaliana aco2 in complex with poa Phyre2 PDB 6g1c chain V Region: 161 - 206 Aligned: 43 Modelled: 46 Confidence: 26.1% Identity: 14% PDB header:antitoxin Chain: V: PDB Molecule:antitoxin hicb; PDBTitle: crystal structure of the n-terminal domain of burkholderia2 pseudomallei antitoxin hicb Phyre2 PDB 1gp6 chain A Region: 125 - 162 Aligned: 38 Modelled: 38 Confidence: 26.0% Identity: 16% Fold: Double-stranded beta-helix Superfamily: Clavaminate synthase-like Family: Penicillin synthase-like Phyre2 1 d1ojra_ 2 c4c24A_ 3 d1e4cp_ 4 c6btdA_ 5 c3ocrA_ 6 c4xxfA_ 7 c2z7bA_ 8 c2opiB_ 9 d1k0wa_ 10 c2fk5B_ 11 d1pvta_ 12 c4m6rA_ 13 c2irpA_ 14 c3m4rA_ 15 c4xaeB_ 16 d1w9ya1 17 d1odma_ 18 c5gj9A_ 19 c6g1cV_ 20 d1gp6a_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99