1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	R	Q	Q	L	A	H	L	L	R	R	A	C	A	V	V	G	D	V	D	V	L	V	L	G	S	Q	S	I	L	G	S	F	D	E	N	E	L	P	P	Q	A	T	A	S	Q	E	A	D	I	A	F	V	N	D	P	A	R	D
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		K	A	D	H	V	D	V	A	I	G	E	M	S	D	F	H	R	S	N	G	V	Y	A	E	G	V	H	I	D	T	A	I	L	P	N	G	W	R	D	R	L	V	S	W	T	V	E	S	S	R	P	A	K	P	R	F	L	E	P	H
Secondary structure
SS confidence
Disorder																																																?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	L	A	V	A	K	L	A	A	G	R	E	K	D	K	A	F	V	A	A	L	I	R	S	G	L	L	D	V	G	V	I	Q	A	R	V	L	L	L	P	E	E	T	D	P	R	I	G	Q	R	I	A	A	W	L	N	Y	Y	G	A
Secondary structure
SS confidence
Disorder										?																			?										?	?	?	?	?	?	?	?	?													?	?
Disorder confidence
		.	.	.	.	.
Sequence		G	N	H	S	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 12%) Alpha helix ( 52%) Beta strand ( 9%)

Rank Aligned region

PDB 4e8i chain A Region: 1 - 143 Aligned: 129 Modelled: 143 Confidence: 86.8% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:lincosamide resistance protein; PDBTitle: crystal structure of lincosamide antibiotic adenylyltransferase lina,2 apo Phyre2 PDB 1no5 chain A Region: 1 - 29 Aligned: 29 Modelled: 29 Confidence: 54.7% Identity: 24% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: Catalytic subunit of bi-partite nucleotidyltransferase Phyre2 PDB 1wot chain A Region: 1 - 27 Aligned: 27 Modelled: 27 Confidence: 54.2% Identity: 37% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: Catalytic subunit of bi-partite nucleotidyltransferase Phyre2 PDB 2mdw chain A Region: 92 - 101 Aligned: 10 Modelled: 10 Confidence: 50.3% Identity: 50% PDB header:de novo protein Chain: A: PDB Molecule:designed protein; PDBTitle: nmr structure of a strand-swapped dimer of the ww domain Phyre2 PDB 2ky8 chain A Region: 88 - 119 Aligned: 32 Modelled: 32 Confidence: 48.6% Identity: 25% PDB header:transcription/dna Chain: A: PDB Molecule:methyl-cpg-binding domain protein 2; PDBTitle: solution structure and dynamic analysis of chicken mbd2 methyl binding2 domain bound to a target methylated dna sequence Phyre2 PDB 3fm2 chain A Region: 6 - 31 Aligned: 25 Modelled: 26 Confidence: 44.1% Identity: 32% PDB header:heme-binding protein Chain: A: PDB Molecule:uncharacterized protein, distantly related to a heme PDBTitle: crystal structure of a putative heme-binding protein (ava_4353) from2 anabaena variabilis atcc 29413 at 1.80 a resolution Phyre2 PDB 1ig4 chain A Region: 88 - 119 Aligned: 32 Modelled: 32 Confidence: 39.4% Identity: 22% Fold: DNA-binding domain Superfamily: DNA-binding domain Family: Methyl-CpG-binding domain, MBD Phyre2 PDB 1ylq chain A domain 1 Region: 6 - 29 Aligned: 24 Modelled: 24 Confidence: 38.4% Identity: 17% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: Catalytic subunit of bi-partite nucleotidyltransferase Phyre2 PDB 2l9d chain A Region: 81 - 102 Aligned: 22 Modelled: 22 Confidence: 36.3% Identity: 23% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of the protein yp_546394.1, the first structural2 representative of the pfam family pf12112 Phyre2 PDB 1ub1 chain A Region: 84 - 119 Aligned: 36 Modelled: 36 Confidence: 35.8% Identity: 25% Fold: DNA-binding domain Superfamily: DNA-binding domain Family: Methyl-CpG-binding domain, MBD Phyre2 PDB 3zvr chain A Region: 4 - 29 Aligned: 26 Modelled: 26 Confidence: 33.7% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:dynamin-1; PDBTitle: crystal structure of dynamin Phyre2 PDB 1tu1 chain A Region: 86 - 106 Aligned: 21 Modelled: 21 Confidence: 30.6% Identity: 19% Fold: Mog1p/PsbP-like Superfamily: Mog1p/PsbP-like Family: PA0094-like Phyre2 PDB 2gc6 chain A domain 1 Region: 4 - 32 Aligned: 29 Modelled: 29 Confidence: 27.8% Identity: 17% Fold: MurD-like peptide ligases, peptide-binding domain Superfamily: MurD-like peptide ligases, peptide-binding domain Family: Folylpolyglutamate synthetase, C-terminal domain Phyre2 PDB 3snh chain A Region: 21 - 29 Aligned: 9 Modelled: 9 Confidence: 26.3% Identity: 44% PDB header:endocytosis Chain: A: PDB Molecule:dynamin-1; PDBTitle: crystal structure of nucleotide-free human dynamin1 Phyre2 PDB 5xmc chain A Region: 81 - 118 Aligned: 31 Modelled: 38 Confidence: 25.3% Identity: 32% PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase itchy; PDBTitle: crystal structure of the auto-inhibited nedd4 family e3 ligase itch Phyre2 PDB 2qdy chain A domain 1 Region: 132 - 176 Aligned: 45 Modelled: 45 Confidence: 23.0% Identity: 27% Fold: Nitrile hydratase alpha chain Superfamily: Nitrile hydratase alpha chain Family: Nitrile hydratase alpha chain Phyre2 PDB 1v29 chain A Region: 133 - 176 Aligned: 44 Modelled: 44 Confidence: 22.9% Identity: 27% Fold: Nitrile hydratase alpha chain Superfamily: Nitrile hydratase alpha chain Family: Nitrile hydratase alpha chain Phyre2 PDB 3qyh chain G Region: 135 - 176 Aligned: 42 Modelled: 42 Confidence: 22.6% Identity: 31% PDB header:lyase Chain: G: PDB Molecule:co-type nitrile hydratase alpha subunit; PDBTitle: crystal structure of co-type nitrile hydratase beta-h71l from2 pseudomonas putida. Phyre2 PDB 4l9c chain A Region: 78 - 97 Aligned: 20 Modelled: 20 Confidence: 22.5% Identity: 20% PDB header:protein binding Chain: A: PDB Molecule:f-box only protein 7; PDBTitle: crystal structure of the fp domain of human f-box protein fbxo72 (native) Phyre2 PDB 2ysc chain A Region: 85 - 100 Aligned: 16 Modelled: 16 Confidence: 22.4% Identity: 38% PDB header:protein binding Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding family PDBTitle: solution structure of the ww domain from the human amyloid2 beta a4 precursor protein-binding family b member 3, apbb3 Phyre2 1 c4e8iA_ 2 d1no5a_ 3 d1wota_ 4 c2mdwA_ 5 c2ky8A_ 6 c3fm2A_ 7 d1ig4a_ 8 d1ylqa1 9 c2l9dA_ 10 d1ub1a_ 11 c3zvrA_ 12 d1tu1a_ 13 d2gc6a1 14 c3snhA_ 15 c5xmcA_ 16 d2qdya1 17 d1v29a_ 18 c3qyhG_ 19 c4l9cA_ 20 c2yscA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99